Postprandial free fatty acids stimulate the activity of human
corticosteroid binding globulin.
M, Haourigui, Sakr S, Martin M. E, Thobie N, Girard-Globa A,
Benassayag C. and Nunez E. A.
U-224 INSERM and Groupe Lipoproteines, Facult[acute]e de
M[acute]edecine Xavier Bichat, Laboratoire de Biochimie, 75870, BP
146 Paris, France
APStracts 2:0156E, 1995.
The effect of postprandial variation of free fatty acids (FFA) upon
serum corticosteroid binding globulin (CBG) properties and on
cortisol concentrations were explored in 11 women (20-30 years)
during 8h after an oral load of Tallow (26% C16:0, 18% C18:0, and 43%
C18:1), Oleic Sunflower (Oleic Sf) (73% C18:1), Sunflower (Sf) (67%
C18:2) and Mixed oil (Mo) (39% C18:1 and 48% C18:2). Serum FFA
increased little after Sf and Mo, but more than doubled in the late
postprandial period (6 and 8hrs) after Oleic Sf (due to
monounsaturated FFA) or Tallow (due to saturated and monounsaturated
FFA).
Received 15 February 1995; accepted in final form 10 July 1995.
APS Manuscript Number E68-5.
Article publication pending Am. J. Physiol. (Endocrinol. Metab.).
ISSN 1080-4757 Copyright 1995 The American Physiological Society.
Published in APStracts on 30 July 1995.