Properties of postganglionic sympathetic fibers isolated from the right recurrent laryngeal nerve. Bakowiec, Agnieszka, and Pawe Szulczyk. Katedra i Zakad Fizjologii Czowieka, Akademii Medycznej w Warszawie, Krakowskie Przedmiecie 26/28, 00 325 Warszawa, POLAND
APStracts 2:0134A, 1995.
The pattern of response of 45 single postganglionic sympathetic axons dissected from the right recurrent laryngeal nerve was examined in chloralose-anesthetized cats. Both vago-aortic nerves were cut and both sinus nerves were left intact. Each neuron, based on the presence of cardiac and respiratory rhythmicities in its resting activity, and reaction to systemic hypoxia (10% O2 in N2 for 2 min.), was classified into one of three classes. Class I neurons (n=29, 64%) were activated during systemic hypoxia and had a pronounced cardiac and inspiration-related rhythmicity in their resting activity. Class II neurons (n=12, 27%) were inhibited during systemic hypoxia and their cardiac and respiratory rhythmicities were either negligible or totally absent. Class III neurons (n=4, 9%), similarly to class I, had a pronounced cardiac and inspiratory rhythmicity but were not affected by systemic hypoxia. The systemic hypoxia was always accompanied by an increase in blood pressure. We conclude that class I, and possibly class III neurons innervate the arteries of upper airways. We also discuss the possibility that class II neurons are the ones responsible for regulating the smooth muscles of upper airways.

Received 27 December 1994; accepted in final form 16 March 1995.
APS Manuscript Number A1336-4.
Article publication pending Journal of Applied Physiology.
ISSN 1080-4757 Copyright 1995 The American Physiological Society.
Published in APStracts on  4 April 1995.