Assessing total body protein, mineral, and bone mineral content
from total body water and body density.
Siconolfi, Steven F., Randal J. Gretebeck, William W. Wong.
Exercise Physiology Laboratory, Space Biomedical Research Institute
SD5/Space Biomedical Research Institute, NASA Johnson Space Center
NASA Johnson Space Center, Houston, TX 77058 Houston, TX 77058,
Voice: (713) 483-7110, FAX (713) 483-6227, University Space Research
Association, Space Center Drive, Houston, TX 77058, Stable Isotope
Program, USDA/ARS Children's Nutrition Research Center, Department of
Pediatrics, Baylor College of Medicine, 1100 Bates Street, Houston,
TX 77030
APStracts 2:0300A, 1995.
We hypothesized that investigators could assess bone mineral content
(BMC), total body mineral (M), and protein (P) from body water (W)
and density (Db) based on Siri's (15, 16) theory for body composition
analysis. Siri used one or more of the body components and the
densities of the body, fat (F), W, M, and P to estimate one of the
remaining fractional masses. We compared M, BMC, P, F, and FFM in 31
subjects (15F/16M) computed from measures of W and Db with (4C model)
and without (3C model) BMC (from dual x-ray absorptiometry). 4C-P was
calculated by difference (P=FFM-W-M). Mean difference (p>0.05)
ranged from 0.1 to 0.8%. Correlations (+/-SEE%) between 4C and 3C
values were significant (M r=0.907+/-8.8%, BMC r=0.907+/-8.7%, P
r=0.969+/-6.6%, F r=0.998+/-2.0%, and FFM r=0.999+/-0.7%). We
concluded that investigators can assess M, BMC, and P from W and Db.
Received 2 November 1994; accepted in final form 15 June 1995.
APS Manuscript Number A1125-4.
Article publication pending Journal of Applied Physiology.
ISSN 1080-4757 Copyright 1995 The American Physiological Society.
Published in APStracts on 18 July 1995.