The presence of leukocytes, decreased strength, and delayed
soreness in muscle after eccentric exercise.
Macintyre, Donna L., W. Darlene Reid, Donald M. Lyster, Ivan J. Szasz,
Donald C. McKenzie.
School of Rehabilitation Sciences, Division of Nuclear Medicine,
School of Human Kinetics, University of British Columbia, Vancouver,
BC, Canada V6T 2B5
APStracts 2:0486A, 1995.
The purposes of this study were to assess the presence of Technetium
-99m (Tc-99m) white blood cells (WBC) in exercised muscle compared to
non-exercised muscle over time, and to determine the time course of
delayed onset muscle soreness (DOMS) and eccentric torque in ten
female subjects. A pre-test was followed by 300 eccentric repetitions
of the right quadriceps. DOMS and eccentric torque were measured at
two, four, 20, 24, 48 and 72 hours post-exercise. Eccentric torque
was also tested at 0 hour. Radionuclide images of both quadriceps
were taken at two, four, 20 and 24 hours post-exercise. The presence
of Tc-99m WBC in the exercised muscle was significantly greater
(p<0.001) than the non-exercised muscle. Eccentric torque
declined at 0 hour and 24 hours post-exercise. DOMS peaked at 24
hours post-exercise. The presence of Tc-99m WBC in the exercised
muscle in the first 24 hours suggests acute inflammation occurs as a
result of exercise-induced muscle injury. The bimodal pattern of
eccentric torque supports the hypothesis that more than one mechanism
is involved.
Received 5 January 1995; accepted in final form 24 October 1995.
APS Manuscript Number A10-5.
Article publication pending Journal of Applied Physiology.
ISSN 1080-4757 Copyright 1995 The American Physiological Society.
Published in APStracts on 30 November 95