Dynamics of Neurons Controlling Movements of a Locust Hind Leg: Wiener Kernel Analysis of the Responses of Proprioceptive Afferents. Kondoh, Y., J. Okuma, and P. L. Newland. Wako Research Center, Wako, Saitama 351_01, Japan; and Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, England.
APStracts 2:0046N, 1995.
SUMMARY AND CONCLUSIONS
1. The response properties of proprioceptive sensory neurons providing input to the local circuits controlling leg movements of the locust have been analysed by the Wiener kernel method. The proprioceptor, the femoral chordotonal organ, encodes the position and movements of the tibia about the femorotibial joint. 2. Intracellular recordings were made from sensory neurons while the apodeme of the organ was moved with a band-limited Gaussian white noise signal with a cutoff frequency of 27, 58, or 117 Hz. To define the input-output characteristics of the neurons, the first- and second-order Wiener kernels were computed by a cross-correlation between the spike response of the afferents and the white noise stimulus. 3. White noise stimulation elicited sustained spiking in 50 out of 54 afferents throughout the 20-s periods of stimulation and recording. The first-order kernels, the linear response properties, of these afferents were of six basic types that were dependent on the cutoff frequency of the white noise stimulus. These included 1 ) flexion-sensitive afferents that were primarily position sensitive irrespective of stimulus frequency, 2 ) flexion-sensitive afferents that were position sensitive at low frequencies but also coded velocity at higher frequencies, 3 ) flexion-sensitive afferents that coded velocity at all stimulus frequencies, 4 ) flexion-sensitive afferents that coded velocity at low stimulus frequencies but also acceleration at high frequencies, 5 ) extension-sensitive afferents that coded velocity at all stimulus frequencies, and 6 ) extension-sensitive afferents that coded velocity at low stimulus frequencies and acceleration at high frequencies. A seventh type contained the four remaining afferents that adapted rapidly to the stimulus within 3_5 s. These were all extension-acceleration_sensitive irrespective of stimulus frequency. 4. The gain curves (produced by Fourier transform of the 1st- order kernels) and the power spectra of the linear models (produced by convolving the 1st-order kernels with the white noise) demonstrated that responses in the position-sensitive afferents are representative of a constant gain low-pass filter with a cutoff frequency of _80 Hz, whereas those in the velocity- and acceleration-sensitive afferents are band passed, having peaks at 80 Hz. 5. The main nonlinearity was a signal compression in which the diagonal peak(s) of the second-order nonlinear kernels offset one or more peaks of the first-order kernels and represents a rectification or directional sensitivity of the afferents. 6. A summation of the first- and second-order models produced by convolving the stimulus input with the first- and second- order kernels could predict the occurrence of 90% of spikes at best. Thus the two lower order kernels can characterize, in detail, the response dynamics of the afferents.

Received 5 July 1994; accepted in final form 18 January 1995.
APS Manuscript Number J398-4.
Article publication pending J. Neurophysiol.
ISSN 1080-4757 Copyright 1995 The American Physiological Society.
Published in APStracts on  3 April 1995.