Local Control of Veins: Biomechanical, Metabolic, and Humoral Aspects.
Monos, Emil, Viktor Berczi and Gyorgy Nadasy.
Experimental Research Department, Second Institute of Physiology,
Semmelweis, University of Medicine, Budapest, Hungary.
APStracts 2:0001P, 1995.
ABSTRACT
The incidence of vein diseases (varicosity, thrombophlebitis,
phlebosclerosis,orthostatic intolerance) is extremely high. In several
countries it may exceed that of the arterial pathology by an order of
magnitude. In the last decades, this recognition and the rapid accumulation
of experimental data have resulted in a progressive reevaluation of the
physiological significance of the venous system, which had been rather
neglected earlier by scientists. The major aim of this review is to provide a
critical survey of recent selected literature related to different
physiological functions of the venous system as well as to biomechanical,
metabolic, and humoral (ionic, hormonal) aspects of the local venous control.
Local neural control mechanisms, including effects of catecholamines and other
transmitters, are regarded to be beyond the scope of this work. At present,
the synthesis of information available in the literature meets certain
difficulties, because occasionally poorly defined methodological techniques
and physiological parameters have been applied. On the other hand, a
significant part of works dealing with venous physiology is excellent and
inspirational. We have good reason to believe that the fast accumulation of
reliable scientific data on this very important field will soon reach a new
critical level, then an even more effective integration of knowledge will be
possible.
APS Manuscript Number P-0002-5.
Article publication scheduled July 1995 Physiological Reviews.
ISSN 1080-4757 Copyright 1995 The American Physiological Society.
Published in APStracts on 16 May 1995.