Energy expenditure in rhesus monkeys (macaca mullata) during
spaceflight using doubly labeled water (2h218o).
Stein, T. Peter, Margarita A. Dotsenko, Vladimir I. Korolkov, David W.
Griffin, and Charles A. Fuller.
Section of Neurobiology, Physiology and Behavior and California
Primate Research Center, University of California, Davis, CA, 95616
-8519, Department of Surgery, University of Medicine and Dentistry of
New Jersey School of Osteopathic Medicine, Stratford NJ, 08084;
Institute of Biomedical Problems (IBMP), Moscow, Russia
APStracts 3:0175A, 1996.
The mean daily energy expenditure rates of three Rhesus monkeys
(Macaca mulatta) were determined during spaceflight on the joint
U.S./Russian Cosmos 2044 and 2229 missions by the doubly labeled
water (DLW, 2H218O) method. Inflight values were compared with ground
data obtained from seven measurements taken from six chair adapted
control monkeys. The mean energy expenditure for the ground control
determinations was 94.5 7.0 kcal/kg/day (n=6). The mean inflight
energy expenditure, 55.1 + 8.0 kcal/kg/day (n=3), was significantly
less than the mean ground control values (p<0.05). These data
suggest that energy expenditure in restrained Rhesus monkeys is
significantly reduced during spaceflight.
Received 28 December 1994; accepted in final form 27 December
1995.
APS Manuscript Number A1370-4.
Article publication pending Journal of Applied Physiology.
ISSN 1080-4757 Copyright 1996 The American Physiological Society.
Published in APStracts on 16 April 96