Electrochemical nitric oxide and nitrogen dioxide analyzer for use
with inhaled nitric oxide.
Nelin, Leif D, N Thomas Christman, James F Morrisey, and Christopher A
Dawson.
Departments of Pediatrics and Physiology, Medical College of
Wisconsin, Research Service, Zablocki VAMC, and Biomedical
Engineering Department, Marquette University, Milwaukee, WI
APStracts 3:0184A, 1996.
The use of inhaled nitric oxide (NO) in research and clinical
applications requires the monitoring of NO and its auto-oxidation
product nitrogen dioxide (NO2) in inspired gas and in the ambient
environment. We describe an inexpensive electrochemical NO and NO2
analyzer using a critical orifice constant flow controller and a
microprocessor cross-over correction for the measurement of NO and
NO2 in the concentration range relevant to the use of inhaled NO. The
analyzer proved to have good accuracy and precision for NO and NO2 in
therange of concentrations relevant to studies of inhaled NO. In this
range the performance was similar to that of a chemiluminescence
analyzer, and the response characteristics were not affected by
varying the oxygen concentration of the mixtures analyzed.
Received 4 January 1996; accepted in final form 27 March 1996.
APS Manuscript Number A18-6.
Article publication pending Journal of Applied Physiology.
ISSN 1080-4757 Copyright 1996 The American Physiological Society.
Published in APStracts on 16 April 96