Predicting body cell mass with bioimpedance using theoretical
methods.
Lorenzo, A. De, A. Andreoli, J. Matthie, and P. Withers.
University of Rome `Tor Vergata', Rome, Italy and Xitron
Technologies, Inc., San Diego, California, USA
APStracts 3:0531A, 1996.
The body cell mass (BCM), defined as intracellular water (ICW), was
estimated in 73 healthy males and females by total body potassium and
by bioimpedance spectroscopy (BIS). In 14 other subjects
extracellular water (ECW) and total body water (TBW) was measured by
bromide dilution and deuterium oxide dilution, respectively. For all
subjects, impedance spectral data were fit to the Cole model and ECW
and ICW volumes predicted using model terms RE and RI in an equation
derived from Hanai mixture theory. The BIS ECW prediction bromide
dilution was r = 0.91, SEE 0.90 L. The BIS TBW prediction of
deuterium space was r = 0.95, SEE 1.33 L. The BIS ICW prediction of
the dilution determined ICW was r = 0.87, SEE 1.69 L. The BIS ICW
prediction of the TBK determined ICW for the 73 subjects was r =
0.85, SEE = 2.22 L. These results add further support to the validity
of the Hanai theory, the equation used and that ECW and ICW volume
can be predicted by an approach based solely on fundamental
principles.
Received 23 May 1996; accepted in final form 13 November 1996.
APS Manuscript Number A489-6.
Article publication pending Journal of Applied Physiology.
ISSN 1080-4757 Copyright 1996 The American Physiological Society.
Published in APStracts on 31 December 1996