Enlargement of glycogen store in rat liver and muscle by fructose
diet intake and exercise training.
Murakami, Taro, Yoshiharu Shimomura, Noriaki Fujitsuka, Koji Okamura,
and Shuichi Sakamoto.
Department of Bioscience, Nagoya Institute of Technology, Gokiso,
Showa-Ku, Nagoya 466, Japan, Otsuka Pharmaceutical Co., LTD.,
Kanzaki-Gun, Saga 842-01, Japan
APStracts 3:0536A, 1996.
This study investigated the effect of long-term intake of a fructose
diet and exercise training on glycogen content in liver and skeletal
muscle in female rats. Thirty-six rats (8 weeks old) were divided
into two dietary groups and were fed with control (chow) diet or
fructose diet (containing 20% fructose) for 12 weeks. During this
period, half of rats in each dietary group were trained using a
motor-driven treadmill (running speed 25 m/min and duration for 90
min/day, 5 days/week). The liver glycogen was increased by intake of
a fructose diet and exercise training and the content was as
following order; control diet-sedentary rats < fructose diet
-sedentary rats < control diet-trained rats < fructose diet
-trained rats at the ratio of 1:3.4:3.6:5.0. The glycogen content in
gastrocnemius muscle showed the same trend as that in liver; the
ratio of 1:1.3:1.3:1.6. These results indicate that both long-term
intake of the fructose diet and exercise training synergistically
increased glycogen in both tissues.
Received 25 September 1995; accepted in final form 12 November
1996.
APS Manuscript Number A1034-5.
Article publication pending Journal of Applied Physiology.
ISSN 1080-4757 Copyright 1996 The American Physiological Society.
Published in APStracts on 31 December 1996