APStracts (ISSN 1080-4757) Vol. 3, 1996

The American Physiological Society

• Surfactant metabolism in surfactant protein a deficient mice. Ikegami, Machiko, Thomas R. Korfhagen, Michael D. Bruno, Jeffrey A. Whitsett, Alan H. Jobe. Department of Pediatrics, UCLA School of Medicine, Harbor-UCLA Medical Center, Torrance, CA 90509, Department of Pediatrics, Division of Pulmonary Biology, Cincinnati Children's Hospital, Cincinnati, OH 45229 APStracts 3:0199L, 1996.
• Tnf[alpha] inhibits isoproterenol-stimulated adenylyl cyclase activity in cultured airway smooth muscle cells. Emala, C. W., J. Kuhl, C. L. Hungerford, and C. A. Hirshman. Departments of Anesthesiology, Medicine and Environmental Health Sciences, The Johns Hopkins Medical Institutions APStracts 3:0200L, 1996.
• Enhanced alveolar type ii cell growth on a pulmonary extracellular matrix over fibroblasts. Adamson, I. Y. R., L. Young, and J. Bakowska. Department of Pathology, University of Manitoba, Winnipeg, Canada APStracts 3:0201L, 1996.
• Camp and genistein stimulate hco3 conductance through cftr in human airway epithelia. Illek, Beate, James R. Yankaskas, and Terry E. Machen. University of California at Berkeley, Department of Molecular and Cell Biology, Division of Cell and Developmental Biology, 231 Life Science Addition, Berkeley, California 94720-3200, USA, Phone: (412) 648 8963, Fax: (412) 648 8330, E-mail: Beate+@Pitt.EDU or Machen@garnet.Berkeley.EDU APStracts 3:0202L, 1996.
• Rna in polysomes is an inhibitor of manganese superoxide dismutase rna-binding protein activity. Chung, David J., and Linda Biadasz Clerch. Lung Biology Laboratory, Departments of Physiology and Biophysics and Pediatrics, Georgetown University School of Medicine, Washington, DC 20007 APStracts 3:0203L, 1996.
• Increased cyclic amp levels in stimulated neutrophils inhibit their adhesion to human bronchial epithelial cells. Bloemen, Pauline G. M., Marja C. Van Den Tweel, Paul A. J. Henricks, Ferdi Engels, Monique H. A. Kester, Peet G. F. Van De Loo, Frans J. Blomjous, and Frans P. Nijkamp. Department of Pharmacology and Pathophysiology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, and Department of Pathology, St. Antonius Hospital Nieuwegein, The Netherlands APStracts 3:0204L, 1996.
• Developmental changes of fetal rat lung na,k-atpase following maternal treatment with dexamethasone. Ingbar, David H., Sara Duvick, S. Kay Savick, Dennis E. Schellhase, Robin Detterding, James D. Jamieson, and John M. Shannon. Department of Medicine, University of Minnesota, Minneapolis, MN; Departments of Medicine and Cell Biology, Yale University School of Medicine, New Haven, CT, and Departments of Medicine and Pediatrics, National Jewish Asthma Center and the University of Colorado Health Sciences Center, Denver, CO APStracts 3:0205L, 1996.
• Mechanism of hemoglobin-induced protection against endotoxemia in rats: a ferritin independent pathway. Otterbein, Leo, Beek Yoke Chin, Sherrie L. Otterbein, Valerie C. Lowe, Henry E. Fessler, and Augustine M. K. Choi. Division of Pulmonary & Critical Care, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 and Scios-Nova Pharmaceutical Inc., Baltimore, Maryland 21224 APStracts 3:0206L, 1996.
• Stabilization of lung surfactant particles against conversion by a cycling interface. Hall, S. B., R. W. Hyde, and M. C. Kahn. Department of Medicine, Oregon Health Sciences University, Portland, Oregon and Departments of Medicine and Environmental Medicine, University of Rochester, Rochester, New York APStracts 3:0207L, 1996.
• Human airway epithelial cells express interleukin-2 in vitro. Aoki, Yosuke, Daoming Qiu, Anne Uyei, and Peter N. Kao. Pulmonary and Critical Care Medicine, Stanford University Medical Center, MSLS P322, Stanford, CA 94305 APStracts 3:0208L, 1996.
• Chronic lung injury in preterm lambs: disordered pulmonary elastin deposition. Pierce, Richard A, Kurt H Albertine, Barry C Starcher, John F Bohnsack, David P Carlton, and Richard D Bland. Department of Internal Medicine, Washington University School of Medicine at Barnes-Jewish Hospital, St. Louis, MO 63110, Department of Pediatrics, Division of Developmental Lung Biology, University of Utah School of Medicine, Salt Lake City, UT 84132, Department of Biochemistry, University of Texas, Tyler, TX 75710 APStracts 3:0209L, 1996.
• Effect of hyperoxia on adhesion molecule expression in human endothelial cells and neutrophils. Suzuki, Yukio, Takuya Aoki, Osamu Takeuchi, Kazumi Nishio, Kouichi Suzuki, Atsushi Miyata, Yoshitaka Oyamada, Tomoaki Takasugi, Masaaki Mori, Hirofumi Fujita, and Kazuhiro Yamaguchi. Department of Internal Medicine and Division of BioMedical Research, BioMedical Laboratory, Kitasato Institute Hospital, Tokyo 108, Department of Medicine, School of Medicine, Keio University, Tokyo 160, JAPAN APStracts 3:0210L, 1996.
• Differential effects of polycationic protein on cl- secretory and na& absorptive airways. Smith, Michael D., Christopher M. Penland, and Michael R. Van Scott. Department of Physiology, East Carolina University School of Medicine, Greenville, NC APStracts 3:0211L, 1996.
• Mechanical forces alter growth factor release by pleural mesothelial cells. Waters, Christopher M., Julie Y. Chang, Mathew R. Glucksberg, Natacha Depaola, and James B. Grotberg. Departments of Anesthesia and Biomedical Engineering, Northwestern University, Chicago, IL 60611 APStracts 3:0212L, 1996.
• Leukotrienes are indicated as mediators of hyperoxia-inhibited alveolarization in newborn rats.. Boros, Veronika, Jacqueline S. Burghardt, Catherine J. Morgan, and David M. Olson. Departments of Pediatrics, Physiology, and Obstetrics and Gynecology, Perinatal Research Centre, The University of Alberta, Edmonton, Alberta, Canada and the Department of Pediatrics, Szent Janos Hospital, Budapest, Hungary APStracts 3:0213L, 1996.
• Separation of human alveolar macrophages by flow cytometry. Maus, Ulrich, Simone Rosseau, Werner Seeger, and J[umlaut]urgen Lohmeyer. Department of Internal Medicine, Justus-Liebig-University, Giessen, Germany APStracts 3:0214L, 1996.
• Ontogeny of [delta]-glutamyl transferase in the rat lung. Oakes, Sean M., Yuji Takahashi, Mary C. Williams, and Martin Joyce -Brady. Pulmonary Center, Department of Medicine, Boston University School of Medicine APStracts 3:0215L, 1996.
• Most basal isc in calu-3 human airway cells is bicarbonate dependent cl secretion. Singh, Meetpaul, Mauri Krouse, Samina Moon, and Jeffrey J. Wine. Cystic Fibrosis Research Laboratory, Stanford University, Stanford, CA 94305-2130 APStracts 3:0216L, 1996.
• The endothelin-a receptor antagonist bq610 blocks cigarette smoke induced mitogenesis in rat airways and vessels. Dadmanesh, F., and J. L. Wright. Department of Pathology, University of British Columbia APStracts 3:0217L, 1996.
• Glycosaminoglycans regulate the inhibition of human leukocyte elastase by oxidized secretory leukoprotease inhibitor. Ying, Qi-Long, Michael Kemme, Derek Saunders, Sanford R. Simon. Departments of Pathology and Biochemistry and the Institute for Cell and Developmental Biology, State University of New York at Stony Brook, Stony Brook, New York 11794, USA, Institut f[umlaut]ur Biochemie, Technische Hochschule Darmstadt, Petersenstra[beta]e 22, D-64287 Darmstadt, and Department of Biotechnological Development, Gr[umlaut]unenthal GMBH, D-52220 Stolberg, Germany APStracts 3:0218L, 1996.
• Differential expression of fibronectin and chronic lung injury by anthropogenic combustion particles in three rat strains. Kodavanti, Urmila P., Richard H. Jaskot, Wei Yi Su, Daniel L. Costa, Andrew J. Ghio, and Kevin L. Dreher. Pulmonary Toxicology Branch, Experimental Toxicology Division, Human Studies Division, National Health and Environmental Effects Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, NC 27711 and Duke University Medical Center, Durham, NC, 27710 APStracts 3:0219L, 1996.
• Nitric oxide inhibits acetylcholine-induced intracellular calcium oscillations in porcine tracheal smooth muscle. Prakash, Y. S., Mathur S. Kannan, and Gary C. Sieck. Departments of Anesthesiology, and Physiology & Biophysics, Mayo Foundation, Rochester, MN 55905, Department of Veterinary PathoBiology and Pediatrics, University of Minnesota, St. Paul, MN 55108 APStracts 3:0220L, 1996.
• Contribution of protein kinase c to [beta] -hexosaminidase-induced airway smooth muscle proliferation. Lew, D. Betty, Eric R. Brown, B. Kinard Dempsey, Harold M. Wright, and Kafait U. Malik. Crippled Children's Foundation Research Center at LeBonheur Children's Medical Center, Departments of Pediatrics and Pharmacology, College of Medicine, University of Tennessee, Memphis, Tennessee 38103 APStracts 3:0221L, 1996.
• Nitric oxide attenuates lung endothelial injury caused by sublethal hyperoxia in rats. McElroy, M. C., J. P. Wiener-Kronish, H. Miyazaki, T. Sawa, K. Modelska, L. G. Dobbs, and J. F. Pittet. Cardiovascular Research Institute, and Departments of Anesthesia and Medicine, Univ. of California, San Francisco, CA, 94143 APStracts 3:0222L, 1996.
• Cell proliferation contributes to pulmonary neuroendocrine cell hyperplasia following acute airway injury. Stevens, Timothy P., John T. McBride, Janice L. Peake, Kent E. Pinkerton, Barry R. Stripp. Departments of Pediatrics and Environmental Medicine, School of Medicine and Dentistry, University of Rochester, Rochester NY, USA, _Department of Anatomy, School of Veterinary Medicine, University of California, Davis, Davis California, USA APStracts 3:0223L, 1996.
• Qualitative immunoblot analysis of pkc isoforms expressed in airway smooth muscle. Togashi, Hideaki, Carol A. Hirshman, and Charles W. Emala. Departments of Anesthesiology* and Environmental Health Sciences, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21205 APStracts 3:0224L, 1996.
• Effects of hyperoxia on type ii cell na,k-atpase function and expression. Carter, Ethan P., O. Douglas Wangensteen, Scott M. Oogrady, David H. Ingbar. Departments of Physiology, Medicine and Pediatrics, School of Medicine, University of Minnesota, Minneapolis, MN 55455 APStracts 3:0225L, 1996.
• Regulated stimulation of epithelial cell dna synthesis by fibroblast-derived mediators. Pasternack, Morris, Xiaoli Liu, Robert A. Goodman, and D. Eugene Rannels. Departments of Medicine, Cellular & Molecular Physiology, and Anesthesia APStracts 3:0226L, 1996.
• Pulmonary soluble guanylate cyclase, a nitric oxide receptor, is increased during the perinatal period. Bloch, Kenneth D., Galina Filippov, Lucienne S. Sanchez, Masaki Nakane, and Suzanne M. De La Monte. Cardiovascular Research Center and the Cancer Center of the Medical Services and the Departments of & Anesthesia and Pathology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, and Abbott Laboratories, Inc., Abbott Park, IL. APStracts 3:0227L, 1996.
• Thrombin inhibits myosin light chain dephosphorylation in endothelial cells. Shasby, D. Michael, Troy Stevens, Dana Ries, Alan B. Moy, Jay M. Kamath, Anant M. Kamath, and Sandra S. Shasby. Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, IA (1) and the Department of Pharmacology, University of South Alabama Mobile, AL (2). This work was conducted in part during Dr. A.B. MoyOs tenure as a Physician Scientist of the American Heart Association. The work was also supported by NIH grant HL 33540 APStracts 3:0228L, 1996.
• Ozone-induced il-8 expression and transcription factor binding in respiratory epithelial cells. Jaspers, I., E. Flescher, L. C. Chen. Department of Environmental Medicine, New York University Medical Center, Tuxedo, NY 10987 APStracts 3:0229L, 1996.
• Glucocorticoid treatment decreases muscarinic receptor expression in canine airway smooth muscle. Emala, C. W., J. Clancy, and C. A. Hirshman. Depts of Anesthesiology and Environmental Health Sciences, Johns Hopkins Medical Institutions, Baltimore, Maryland 21205 APStracts 3:0230L, 1996.
• Effect of anion transport inhibition on mucus secretion by airway submucosal glands. Inglis, Sarah K., Michel R. Corboz, Aubrey E. Taylor, and Stephen T. Ballard. Department of Physiology, College of Medicine, University of South Alabama, Mobile, AL 36688 APStracts 3:0231L, 1996.
• Nitric oxide as an inflammatory mediator of radiation pneumonitis in rats. Nozaki, Yasuhiro, Yoshinori Hasegawa, Akihide Takeuchi, Zuo-Heng Fan, Ken-Ichi Isobe, Izumi Nakashima, Kaoru Shimokata. First Department of Internal Medicine and Department of Immunology, Nagoya University School of Medicine, Showa-ku, Nagoya, Japan. Department of Immunology, National Institute for Longevity Sciences, Ohbu, Aichi, Japan APStracts 3:0232L, 1996.
• Localization of cholinergic nerves in the lower airways of the guinea pig using antisera to choline acetyltransferase. Canning, Brendan J., and Axel Fischer. The Johns Hopkins Asthma & Allergy Center, 5501 Hopkins Bayview Circle, Baltimore, MD 21224 USA (BJC) and Institute for Anatomy and Cell Biology, Justus-Liebig-University Giessen, Germany (AF) APStracts 3:0233L, 1996.
• Activation of endothelial cell phospholipase d by polycations. V., Suryanarayana, Scribner, W. M. and Natarajan. V. Department of Medicine, Indiana University School of Medicine, Indianapolis, IN USA APStracts 3:0234L, 1996.
• Pulmonary mechanical and immunologic dysfunction in a murine model of aids. Hartsfield, Cynthia L., David Lipke, Yih-Loong Lai, Donald A. Cohen, and Mark N. Gillespie. University of Kentucky A.B. Chandler Medical Center, College of Pharmacy, Division of Pharmacology and Experimental Therapeutics, and College of Medicine, Department of Microbiology and Immunology, Lexington, KY 40536-0082 APStracts 3:0235L, 1996.
• Laminin e8 alveolarization site: heparin sensitivity, putative nonintegrin receptors and role in cell spreading. Chen, Lanlin, Vladislav Shick, Michelle L. Matter, Susan M. Laurie, Roy C. Ogle, and Gordon W. Laurie. Department of Cell Biology, University of Virginia, Charlottesville, VA, Department of Neurological Surgery, University of Virginia, Charlottesville, VA APStracts 3:0236L, 1996.