APStracts 3:0073F, 1996.

The effect of atrial natriuretic peptide on renal hemodynamics and sodium excretion during human pregnancy . Irons, D. W., P. H. Baylis, and J. M. Davison. Department of Obstetrics and Gynaecology, 4th Floor Leazes Wing, Royal Victoria Infirmary, Newcastle upon Tyne, NE1 4LP, U.K. and Department of Medicine, University of Newcastle upon Tyne, UK.

APStracts 3:0073F, 1996.

The effect of infused atrial natriuretic peptide (ANP) on sodium excretion (UNa), glomerular filtration rate (GFR) and effective renal plasma flow (ERPF) was studied in 12 normotensive primigravidae at 32 weeks gestation (late pregnancy, [LP]) and again 4 months post-partum (non pregnant, [NP]). Three 20 min steady state (renal) clearances of inulin and para-aminohippurate were used to measure GFR and ERPF, respectively, before and after infusion of ANP at 2 pmol/kg/min.

Received 13 November 1995; accepted in final form 10 April 1996.
APS Manuscript Number F383-5.
Article publication pending Am. J. Physiol. (Renal Fluid Electrolyte
Physiology).
ISSN 1080-4757 Copyright 1996 The American Physiological Society.
Published in APStracts on 23 April 96