Density of fat-free body mass: relationship with race, age, and level of body fatness. Visser, Marjolein, Dympna Gallagher, Paul Deurenberg, Jack Wang, Richard N Pierson, Steve B Heymsfield. Department of Human Nutrition, Wageningen Agricultural University, Wageningen, the Netherlands, Department of Medicine, Obesity Research Center, St.Luke's-Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY, USA
APStracts 4:0009E, 1997.
The two-compartment body composition method assumes that fat-free body mass (FFM) has a density of 1.100 kg/L. This study tested the hypothesis that FFM density is independent of race, age, and body fatness. Subjects were 703 black and white subjects, ages 20-94 years, with body mass index (BMI) 17-35 kg/m2. Body composition was assessed using a four-compartment model based on tritium dilution volume, body density by underwater weighing, bone mineral by dual -energy x-ray absorptiometry, and body weight. No relationship was observed between FFM density and race or BMI. A tendency was observed for a lower FFM density only in older white women. The difference in percent body fat (_fat) between the four-compartment model and underwater weighing was <2% for all groups. Race, age, and BMI explained only 2.3% (women) and 1.4% (men) of the variance in _fat, while the total body water fraction of FFM explained 77%. In contrast to current thinking, these results show that the assumption of constant FFM density is valid in black, elderly, and obese subjects.

Received 2 July 1996; accepted in final form 31 December 1996.
APS Manuscript Number E312-6.
Article publication pending Am. J. Physiol. (Endocrinol. Metab.).
ISSN 1080-4757 Copyright 1997 The American Physiological Society.
Published in APStracts on 19 February 1997