APStracts 4:0174N, 1997.

An Analysis of Primate Inhibitory Burst Neuron Spike Trains using System Identification Techniques: Relationship to Eye Movement Dynamics during Head- Fixed Saccades. Kathleen E. Cullen and Daniel Guitton. Aerospace Medical Research Unit and the Montreal Neurological Institute, McGill University, Montreal, Quebec H3G 1Y6, Canada.

APStracts 4:0174N, 1997.

ABSTRACT
The dynamic behavior of primate (Macaca fasicularis) inhibitory burst neurons (IBNs) during head-fixed saccades was analyzed using system identification techniques. Neurons were categorized as IBNs on the basis of their anatomical location, as well as by their activity during horizontal head-fixed saccadic and smooth pursuit eye movements, and vestibular nystagmus. Each IBN’s latency or “dynamic lead time” (td) was determined by shifting the unit discharge in time until an optimal fit to the firing rate frequency, B(t), profile was obtained using the simple model based on eye movement dynamics, B(t) = r + b1E((t); where E( is eye velocity. For the population of IBNs, the dynamic estimate of lead time provided a significantly lower value than a method which used the onset of the first spike.

Received 13 August 1996; accepted in final form 2 July 1997.
APS Manuscript Number J648-6.
Article publication pending J. Neurophysiol.
ISSN 1080-4757 Copyright 1997 The American Physiological Society.
Published in APStracts on 28 August 1997