Muscle fibers in regenerating crayfish motor nerves.
Joanne Pearce, Kristin M. Krause and C.K. Govind.
Life Sciences Division, University of Toronto at Scarborough, 1265 Military
Trail, Scarborough, Ontario M1C 1A4, Canada, and 2St Thomas Aquinas College,
125 Route 340, Sparkill, New York 10976, USA..
APStracts 4:196N, 1997.
ABSTRACT
Single discrete muscle fibers were found in regenerating motor nerves in adult
crayfish. The regenerating nerves were from native or transplanted ganglia in
the third abdominal segments and consisted of several motor axons. The
proximal end of these motor axons showed numerous sprouts. Muscle fibers in
these regenerating nerves appeared newly developed and were innervated by
excitatory nerve terminals. A likely source of these novel muscle fibers may
be blood cells in the nerve or satellite cells from neighboring muscle.
Contacts made by axon sprouts with other axon sprouts, glia, and muscle fiber,
in the form of a dense bar with clustered clear vesicles, characterized the
regenerating nerve. These contacts may provide a possible signaling pathway
for axon regeneration and myogenesis.
Received 14 July 1997; accepted in final form 12 August 1997.
APS Manuscript Number J581-7.
Article publication pending J. Neurophysiol.
ISSN 1080-4757 Copyright 1997 The American Physiological Society.
Published in APStracts on 28 August 1997