APStracts (ISSN 1080-4757) Vol. 7, 2000

The American Physiological Society

• Mechanism of dexamethasone-mediated interleukin-8 gene suppression in cultured airway epithelial cells. Chang, Mary Mann-Jong, Maya Juarez, Dallas M. Hyde, and Reen Wu. 1Center for Comparative Respiratory Biology and Medicine, 2Department of Internal Medicine, School of Medicine, and 3Department of Anatomy, Physiology, and Cell Biology, School of Veterinary Medicine, University of California at Davis, Davis, California 95616 APStracts 7:0239L, 2000.
• Activation of epidermal growth factor receptors is responsible for mucin synthesis induced by cigarette smoke. Takeyama, Kiyoshi, Birgit Jung, Jae Jeong Shim, Pierre-Regis Burgel, Trang Dao-Pick, Iris F. Ueki, Ursula Protin, Peer Kroschel, and Jay A. Nadel. 1Cardiovascular Research Institute and Departments of Medicine and Physiology, University of California San Francisco, San Francisco, California 94143«hyphen»0130 and 2Department of Pulmonary Research, Boehringer Ingelheim, 55216 Ingelheim, Germany APStracts 7:0240L, 2000.
• Nitric oxide attenuates H2O2-induced endothelial barrier dysfunction: mechanisms of protection. Gupta, Mahesh P., Michael D. Ober, Carolyn Patterson, Mohammed Al-Hassani, Viswanathan Natarajan, and C. Michael Hart. 1Department of Medicine, Indiana University and Richard L. Roudebush Veterans Affairs Medical Centers, Indianapolis, Indiana 46202; and 2Department of Medicine, Johns Hopkins University, Baltimore, Maryland 21224 APStracts 7:0241L, 2000.
• TNF-alpha and IL-1beta are not essential to the inflammatory response in LPS- induced airway disease. Moreland, Jessica G., Robert M. Fuhrman, Christine L. Wohlford-Lenane, Timothy J. Quinn, Erin Benda, Jonathan A. Pruessner, and David A. Schwartz. 1Department of Pediatrics and 2Pulmonary, Critical Care, and Occupational Medicine Division, Department of Internal Medicine, The University of Iowa, Iowa City, Iowa 52242 APStracts 7:0242L, 2000.
• Muc1 mucins on the cell surface are adhesion sites for Pseudomonas aeruginosa. Lillehoj, E. P., S. W. Hyun, B. T. Kim, X. G. Zhang, D. I. Lee, S. Rowland, and K. C. Kim. Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland 21201 APStracts 7:0243L, 2000.
• Prostaglandin E2-induced interleukin-6 release by a human airway epithelial cell line. Tavakoli, S., M. J. Cowan, T. Benfield, C. Logun, and J. H. Shelhamer. Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland 20892 APStracts 7:0244L, 2000.
• Expression and localization of lung surfactant protein B in Eustachian tube epithelium. Paananen, Reija, Virpi Glumoff, Raija Sormunen, Wim Voorhout and Mikko Hallman. 1Biocenter Oulu, 2Department of Pediatrics, and 3Department of Pathology, University of Oulu, 90014 Oulu, Finland; and 4Department of Biochemistry and Cell Biology, Faculty of Veterinary Medicine, Utrecht University, ?? ???? Utrecht, The Netherlands APStracts 7:0245L, 2000.
• Effect of glycosaminoglycan degradation. Jamal, Rehab Al, Peter J. Roughley, and Mara S. Ludwig. 1Meakins Christie Laboratories, Royal Victoria Hospital and 2Genetics Unit, Shriner's Hospital for Crippled Children, McGill University, Montreal, Quebec, Canada H2X 2P2 APStracts 7:0246L, 2000.
• Regulation of PDGFR-a in rat pulmonary myofibroblasts by staurosporine. Lindroos, Pamela M., Yi-Zhe Wang, Annette B. Rice, and James C. Bonner. Laboratory of Pulmonary Pathobiology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709 APStracts 7:0247L, 2000.
• The NO donor molsidomine reduces endothelin-1 gene expression in chronic hypoxic rat lungs. Blumberg, Friedrich C., Konrad Wolf, Peter Sandner, Cornelia Lorenz, Günter A. J. Riegger, and Michael Pfeifer. 1Department of Internal Medicine II and 2Institute of Physiology, University of Regensburg, 93042 Regensburg, Germany APStracts 7:0248L, 2000.
• Cooperative effects of rhinovirus and atopic sensitization on airway responsiveness. Grunstein, Michael M., Hakon Hakonarson, Richard L. Hodinka, Neil Maskeri, Cecilia Kim, and Sing Chuang. Divisions of Pulmonary Medicine and Allergy, Immunology, and Infectious Diseases, Joseph Stokes, Jr. Research Institute, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 APStracts 7:0249L, 2000.
• Intercellular Ca2+ signaling in alveolar epithelial cells through gap junctions and by extracellular ATP. Isakson, Brant E., W. Howard Evans, and Scott Boitano. 1Department of Zoology and Physiology, University of Wyoming, Laramie, Wyoming 82071«hyphen»3166; and 2Department of Medical Biochemistry, University of Wales College of Medicine, Heath Park, Cardiff CF4 4XN, Wales APStracts 7:0250L, 2000.
• Attenuation of bleomycin-induced pneumopathy in mice by a caspase inhibitor. Kuwano, Kazuyoshi, Ritsuko Kunitake, Takashige Maeyama, Naoki Hagimoto, Masayuki Kawasaki, Tokuji Matsuba, Michihiro Yoshimi, Ichiro Inoshima, Koichiro Yoshida, and Nobuyuki Hara. Research Institute for Diseases of the Chest, Graduate School of Medical Sciences, Kyushu University, Higashiku, Fukuoka 812«hyphen»8582, Japan APStracts 7:0251L, 2000.
• Ion exchange activity in pulmonary artery smooth muscle cells: the response to hypoxia. Madden, Jane A., Daniel E. Ray, Peter A. Keller, and Jack G. Kleinman. Departments of 1Neurology and 3Medicine, The Medical College of Wisconsin, and 2Research Service, Zablocki Veterans Affairs Medical Center, Milwaukee, Wisconsin 53295 APStracts 7:0252L, 2000.
• Connexin expression by alveolar epithelial cells is regulated by extracellular matrix. Guo, Yihe, Cara Martinez-Williams, Clare E. Yellowley, Henry J. Donahue, and D. Eugene Rannels. Departments of 1Cellular and Molecular Physiology, 2Orthopaedics and Rehabilitation, and 3Anesthesia, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033 APStracts 7:0253L, 2000.
• IFN-ß mediates coordinate expression of antigen-processing genes in RSV-infected pulmonary epithelial cells. Mohammad Jamaluddin, Shaofei Wang, Roberto P. Garofalo, Todd Elliott, Antonella Casola, Samuel Baron, and Allan R. Brasier. Departments of 1Medicine and 4Sealy Center for Molecular Science, 2Pediatrics and 3Microbiology and Immunology, The University of Texas Medical Branch, Galveston, Texas 77555«hyphen»1060 APStracts 7:0254L, 2000.
• Cytokines decrease sGC in pulmonary artery smooth muscle cells via NO-dependent and NO-independent mechanisms. Takata, Masao, Galina Filippov, Heling Liu, Fumito Ichinose, Stefan Janssens, Donald B. Bloch, and Kenneth D. Bloch. Cardiovascular Research Center and Arthritis Unit, Massachusetts General Hospital, and Departments of Medicine and Anesthesia, Harvard Medical School, Charlestown, Massachusetts 02129; and Center for Transgene Technology and Gene Therapy, Flanders Interuniversity Institute for Biotechnology, and the Cardiac Unit, University Hospital Gasthuisberg, University of Leuven, Belgium APStracts 7:0255L, 2000.
• Airway vasculature after mycoplasma infection: chronic leakiness and selective hypersensitivity to substance P. Kwan, Marilyn L., Antonio D. Gómez, Peter Baluk, Hiroya Hashizume, and Donald M. McDonald. Cardiovascular Research Institute and Department of Anatomy, University of California, San Francisco, California 94143 APStracts 7:0256L, 2000.
• Il-10 gene knockout attenuates allergen-induced airway hyperresponsiveness in C57bl/6 mice. Justice, J. Paul, Y. Shibata, S. Sur, J. Mustafa, M. Fan, and M. R. Van Scott. 1Departments of Physiology and Pharmacology, Brody School of Medicine at East Carolina University, Greenville, North Carolina 27858; and 2Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas APStracts 7:0257L, 2000.
• Chloride channel function is linked to epithelium-dependent airway relaxation. Fortner, Christopher N., John N. Lorenz, and Richard J. Paul. University of Cincinnati College of Medicine, Department of Molecular and Cellular Physiology, University of Cincinnati, Cincinnati, Ohio 45267 APStracts 7:0258L, 2000.
• Association between airway hyperreactivity and bronchial macrophage dysfunction in individuals with mild asthma. Alexis, Neil E, Joleen Soukup, Stefan Nierkens, and Susanne Becker. 1Center For Environmental Medicine and Lung Biology, University of North Carolina, Chapel Hill 27599; and 2United States Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, RTP, North Carolina 27711 APStracts 7:0259L, 2000.
• Neutrophils induce apoptosis of lung epithelial cells via release of soluble Fas ligand. Serrao, Karl L., James D. Fortenberry, Marilyn L. Owens, Frank L. Harris, and Lou Ann S. Brown. Divisions of 1Critical Care and 2Neonatology, Department of Pediatrics, Emory University School of Medicine, and 3Division of Critical Care Medicine, Children's Healthcare of Atlanta at Egleston, Atlanta, Georgia 30322 APStracts 7:0260L, 2000.
• Requirement for Ca2+ signaling in the mechanism of thrombin-induced increase in endothelial permeability. Sandoval, Raudel, Asrar B. Malik, Tabassum Naqvi, Dolly Mehta, and Chinnaswamy Tiruppathi. Department of Pharmacology, College of Medicine, The University of Illinois at Chicago, Chicago, Illinois 60612 APStracts 7:0261L, 2000.
• Intra-amniotic endotoxin increases pulmonary surfactant proteins and induces SP-B processing in fetal sheep. Bachurski, Cindy J., Gary F. Ross, Machiko Ikegami, Boris W. Kramer, and Alan H. Jobe. Division of Pulmonary Biology, Children's Hospital Research Foundation, Cincinnati, Ohio 45229 APStracts 7:0262L, 2000.
• Toll-like receptor 4 mediates ozone-induced murine lung hyperpermeability via inducible nitric oxide synthase. Kleeberger, Steven R., Sekhar P. M. Reddy, Liu-Yi Zhang, Hye-Youn Cho, and Anne E. Jedlicka. Department of Environmental Health Sciences, The Johns Hopkins University School of Public Health, Baltimore, Maryland 21205 APStracts 7:0263L, 2000.
• Protein tyrosine phosphatase-dependent proteolysis of focal adhesion complexes in endothelial cell apoptosis. Harrington, Elizabeth O., Anthony Smeglin, Julie Newton, Gajarah Ballard, and Sharon Rounds. Pulmonary/Critical Care Medicine Section, Providence Veterans Affairs Medical Center, and Department of Medicine, Brown University School of Medicine, Providence, Rhode Island 02908 APStracts 7:0264L, 2000.
• Phosphodiesterase 5 inhibition restores impaired ACh relaxation in hypertensive conduit pulmonary arteries. Oka, Masahiko. Department of Respiratory Medicine, Juntendo University School of Medicine, Tokyo 113«hyphen»8421, Japan APStracts 7:0265L, 2000.
• l-Arginine attenuates lipopolysaccharide-induced lung chemokine production. Calkins, Casey M., Denis D. Bensard, Julie K. Heimbach, Xianzhong Meng, Brian D. Shames, Edward J. Pulido, and Robert C. McIntyre, Jr. 1Department of Surgery, University of Colorado Health Sciences Center and The Veterans Affairs Hospital, Denver 80262; and 2Department of Pediatric Surgery, The Children's Hospital, Denver, Colorado APStracts 7:0266L, 2000.
• Type 2 rhinovirus infection of cultured human tracheal epithelial cells: role of LDL receptor. Suzuki, Tomoko, Mutsuo Yamaya, Masahito Kamanaka, Yu X. Jia, Katsutoshi Nakayama, Masayoshi Hosoda, Norihiro Yamada, Hidekazu Nishimura, Kiyohisa Sekizawa, and Hidetada Sasaki. 1Department of Geriatric and Respiratory Medicine, Tohoku University School of Medicine, Sendai 980«hyphen»8574; 3Virus Center, Clinical Research Division, Sendai National Hospital, Sendai 983«hyphen»0045; and 2Department of Pulmonary Medicine, Institute of Clinical Medicine, University of Tsukuba, Tsukuba 305«hyphen»8575, Japan APStracts 7:0267L, 2000.