Translating Research
into Medicine
The Center for Translational Injury Research is a part of The University of Texas Health Science Center at Houston.
Research:
PROMMTT
Prospective, Observational, Multi-center Massive Transfusion sTudy
The U.S. Department of Defense has awarded The University of Texas Health Science Center at Houston a grant to conduct a multi-center clinical trial that could lead to an improved survival rate for trauma patients who require massive blood transfusions. www.prommtt.org
PROPPR
Prospective Randomized Optimum Platelet and Plasma Ratios
PROPPR is a multicenter, prospective, randomized trial which will compare different ratios of blood products given to trauma patients who are predicted to require massive transfusions (greater than 10 units of PRBCs within the first 24 hours).
Trauma Research Center
The Trauma Research Center is a multi-institutional, multidisciplinary research unit supported by the National Institute of General Medical Sciences (NIGMS) of the United States' National Institutes of Health (NIH). The Center's major focus is to study the role of plasma in hemorrhagic shock.
Research funded by National Institute of General Medical Sciences P50 GM038529.
Hemorrhagic Shock
The T32 funding mechanism is a federally funded grant mechanism to develop the careers of promising young scientists. Each T32 program has a specific focus, and UTHSCH was awarded this grant in 2001 to investigate the Role of the Gut in Multiple Organ Failure.Since it’s creation, the focus of the research has evolved and is now aimed at the role of plasma in hemorrhagic shock. Currently, three trainees (with a Ph.D. or M.D.) devote themselves for two years to basic science, bench, and clinical research. Funding for renewal was granted in 2006, and currently, Dr. Holcomb is the Principle Investigator of this program. The success of the T32 is due to the combined efforts of faculty members and collaborators.
Mission Connect
Mission Connect is a unique collaborative research effort, led by TIRR Foundation, focusing on basic and clinical research with a goal to reverse the consequences of spinal cord injury, brain injury and neurological disorders. more
Composite Tissue Allotransplantation (CTA)
CTA offers the possibility of restoring physical and emotional wholeness to a population of individuals who may have very few traditional reconstructive options, but because of these technical, medical and psychological challenges, a complete CTA program necessitates a multi-disciplinary approach to the broader application of the technology. UTHealth has a longitudinal experience with solid-organ transplantation and an experienced team of experts, including surgeons, nurses, immunologists and ethicists. MD Anderson's Department of Plastic Surgery has faculty with expertise in microsurgical transfer, hand and facial surgery, as well as research experience in CTA.
