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Associate Professor
Center for Clinical Neurosciences
Department of Children's Learning Institute
University of Texas Medical School/Houston
Houston, Texas, USA

Joshua I. Breier, Ph.D. is a Clinical Neuropsychologist and Associate Professor in the Department of Children's Learning Institute/Center for Clinical Neurosciences at the University of Texas Health Science Center, Houston, Texas. His clinical practice includes evaluation of both children and adults with a wide variety of learning disabilities as well as illnesses affecting the central nervous system referred from neurologists, neurosurgeons, and other medical practitioners throughout the Houston and surrounding areas. Appointments for neuropsychological evaluation can be made by calling 832-325-7090.

Current research projects include imaging of language function using magnetoencephalography in adults with chronic aphasia secondary to stroke and in children as well as adults with epilepsy and co-morbid learning disabilities. Dr. Breier also studies primary processing of acoustic information in children with reading disabilities.

 


 


 

 

 

UNDERGRADUATE EDUCATION

  • B.A. (1969 - 1973) Major: Musical Composition, Berklee College of Music, Boston, Massachusetts.


  • B.S. (1962 - 1966) Major: Biochemistry, Cornell University, Ithaca, New York.

 

GRADUATE EDUCATION

  • APA approved Internship in Clinical Psychology (1992 - 1993), Neuropsychology Specialty Track, Department of Clinical and Health Psychology, University of Florida, Gainesville, Florida.


  • Ph.D. (1991 - 1993) Clinical Neuropsychology, Department of Psychology, University of Houston, Houston, Texas.


  • M.A. (1989 - 1991) Clinical Neuropsychology, Department of Psychology, University of Houston, Houston, Texas.

 

POSTGRADUATE TRAINING

  • Post-Doctoral Research Fellow (1993 - 1994) Neuropsychology Laboratory, Department of Clinical and Health Psychology, University of Florida, Gainesville, Florida.

  • Research: Magnetic resonance imaging of white and gray matter and hippocampal volumes in epilepsy, agnosia for hemiplegia during WADA testing, memory in epilepsy, psychophysiology of implicit memory.

  • Clinical: Neuropsychological assessment in neurological and psychiatric populations.

 

ACADEMIC APPOINTMENTS

  • Assistant Professor (1994 - 1999) Department of Neurosurgery, The University of Texas Medical School/Houston.


  • Associate Professor (1999-present) Department of Neurosurgery, The University of Texas Medical School/Houston.

    Clinical: (1996-present) Head of neuropsychology in the Department of Neurosurgery; Senior adult neuropsychologist at Hermann Hospital. Perform neuropsychological assessment of approximately 250 adult, adolescent, and pediatric patients per year, representing approximately 2000 hours of patient interaction. Approximately 60% of assessment is as the chief neuropsychologist with the Texas Comprehensive Epilepsy Program and includes neuropsychological testing for the purposes of lesion localization, Wada testing, and intraoperative and extraoperative functional mapping of receptive and expressive language cortex.

    Research: Neuropsychological and functional brain mapping (positron emission tomography, magnetoencephalography), and psychoacoustics in clinical populations.

    Teaching: Lectures to Neurology Residents at the University of Texas Medical School at Houston and Graduate students in Psychology at the University of Houston. Serve on the Medical School Admissions Committee as a Faculty Interviewer. Supervise 3 to 4 Neuropsychology Practicum students from the Clinical Psychology Graduate Program, University of Houston and 3 to 4 Post-Doctoral Fellows each year.


  • Adjunct Faculty (1996-present) Department of Psychology, The University of Houston: Train and supervise graduate students in the Clinical Neuropsychology program; sit on Thesis and Dissertation committees, give lectures on neuropsychological assessment and functional imaging.

 

HOSPITAL APPOINTMENTS

  • Credentialed at Hermann Hospital, Houston, Texas

 

LICENSURE

  • Licensed Clinical Psychologist, State of Texas - License # 2-5247

 

CERTIFICATION

  • Certified Clinical Psychologist, State of Texas
     

PROFESSIONAL ORGANIZATIONS:

  • International Neuropsychological Society (1989 - present)

  • Houston Neuropsychological Society (1994-present)

  • American Psychological Association (1998 - present)

  • American Epilepsy Association (1998-present)

  • Society for Neuroscience (1999 – present)

 

EDITORIAL POSITIONS:

 

Ad hoc reviewer for :

  • Developmental Psychology.

  • Epilepsia.

  • Archives of Neurology

  • Scientific Studies of Reading

  • Neuropsychology

  • Developmental Neuropsychology

  • Journal of Experimental Child Psychology

  • Brain Research

  • Learning Disabilities: A Contemporary Journal

 

SERVICE ON THE UNIVERSITY OF TEXAS - HOUSTON MEDICAL SCHOOL COMMITTEES:

  • Faculty Interviewer for prospective medical students (1996-1997)

  • Peer Review Committee, Department of Neurosurgery (1997-1998)

  • Played an integral role in organizing and writing the Department of Neurosurgery Self Study as part of the 6 year Departmental Review  (1997-1998)

  • Faculty Interviewer for prospective medical students (1997-1998);

  • Peer Review Committee, Department of Neurosurgery (1998-1999)

  • Faculty Interviewer for prospective medical students (1998-1999);

  • Peer Review Committee, Department of Neurosurgery (1999-2000)

  • Faculty Interviewer for prospective medical students (1999-2000);

  • Faculty Interviewer for prospective medical students (2000-2001);

  • Faculty Interviewer for prospective medical students (2001-2002);

  • Faculty Senator (1999 - present)

 

SERVICE TO THE COMMUNITY:

  • Science Fair Judge – Poe Elementary School (1998; 1999)

  • Coach children’s athletic teams: Little League Baseball; YMCA Basketball and Soccer; Church League basketball

  • Work with neighborhood Civic Association to reinstate deed restrictions.

  • Board Member – Near Town Little League, Houston, Texas

 

CURRENT TEACHING RESPONSIBILITIES:

  • Supervision of Neuropsychology graduate students from the University of Houston, Department of Psychology in Clinical Practicum.

  • Supervision of 3 to 4 Post-Doctoral Fellows in Neuropsychology

  • Lectures to residents in the Department of Neurology.

  • Guest lecturer at the University of Houston.

  • Reader on comprehensive examinations for PhD candidates at the University of Houston, Department of Psychology.

  • Chair and member of thesis and dissertation committees for graduate students -

  • Member, Dissertation Committee: "The formulation and standardization of a battery of tests of visual-perceptual-motor function for the adult cerebro-vascular accident patient" Marjorie Eileen Concha, Wits University, Johannesburg, South America (1998)

  • Chair, Dissertation Committee:  "Effects of atypical language laterality on memory performance during Wada testing". Kathleen Fuchs - University of Houston Department of Psychology, Neuropsychology Track. (1999)

  • Member, Thesis Committee: “Effects of left temporal lobe epilepsy on the retrieval stage of memory”. Lynne Cole, University of Houston Department of Psychology, Neuropsychology Track. (2000)

  • Chair, Thesis Committee: “Differential effects of language reorganization in response to unilateral left temporal lobe epilepsy on semantic and episodic memory” Allison Clark,  University of Houston Department of Psychology, Neuropsychology Track. (2001)

  • Member, Dissertation Committee: “Organization of language cortex in bilingual speakers using magnetoencephalography” Robert N. Davis, University of Houston Department of Psychology, Neuropsychology Track. (2001)

 

CURRENT GRANT SUPPORT:

  • Principal Investigator (40% effort) – “Functional brain reorganization in recovery from aphasia”. Project 1 of the Program Project Grant entitled “Functional Brain Reorganization in Stroke Recovery” (Andrew C. Papanicolaou, PI). NINDS, NIH Grant 5PO1NS046588.

  • Co-Investigator (5% effort) – "Early Development of Auditory Temporal Processing" Principal Investigator: Lincoln Gray, Ph.D.; NIH $753, 426 (2001-2005).

  • Co-Investigator (25% effort) – “Brain Activation Profiles in Dyslexia: A MEG Study”  (Papanicolaou)   1 RO1 HD38346-01A1,  National Institutes of Health. $ 1,488,374 (2000 - 2005).

 

PAST GRANT SUPPORT:

  • Principal Investigator (40% effort)- “Auditory temporal processing in children with dyslexia”, 1 RO1 HD/DC35938-01A1, National Institute of Child Health and Human Development, $701,335 (1998 - 2003).

  • Co-Investigator (20% effort) - "Contributions of MEG to the Surgical Management of Epilepsy" (Papanicolaou), 1 RO1 NS37941-01A1. National Institutes of Health, $ 2,674,447. (1999-2004).

  • Co- Investigator (5% effort) – "Early Development of Auditory Temporal Processing" Principal Investigator: Lincoln Gray, Ph.D.;  March of Dimes #12-FY-00-0166. $178, 851 (2000-2003).

  • Co- Investigator - (Instrumentation grant) ”Acquisition of Magnetic Source Imaging System for Cognitive and Educational Neruroimaging.” PI: Andrew C. Papanicolaou, National Science Foundation. BCS-0116150. $2,000,000 (2001-2002).     

  • Principal Investigator - “Auditory temporal processing in children with reading disabilities”, 1 12-FY98-0214, March of Dimes Birth Defects Foundation. (1998 - 1999).

  • Co- Investigator - “Effects of early auditory experience on binaural hearing”. NIH grant  5 RO1 DC00018-06 (Gray) 9/1/94 - 9/1/98.         

 

PUBLICATIONS:

 

Abstracts and Presentations:

1.Breitmeyer, B.G., and Breier, J. I.: Background color effects on visual reaction time and scanning rate. Paper presented at the annual meeting of the Psychonomic Society, Washington, D.C., Nov. 5 - 7. 1993.

 

2.Breier, J. I., and Gray, L.:  Sound source localization in pre- and post-operative unilateral atresia patients. Journal of Clinical and Experimental Neuropsychology 15:39, 1993.

 

3.Breier J. I., Culhane K. A., Rettig, G. M., and Rutecki, P. The relationship of indices of language and memory laterality formed from Wada test data to variables affecting interhemispheric reorganization of these functions. Journal of Clinical and Experimental Neuropsychology 15:39, 1993.

 

4.Breier J. I., Leonard C. M., Bauer R. M., Gilmore R., and Roper S.  Interhemispheric asymmetries in an index of temporal lobe cortical volume in patients with temporal lobe epilepsy.  Epilepsia 35:147, 1994.

 

5.Leonard, C. M., Lombardino, L. J., Mercado, L., Foundas, A. L., Browd, S., Breier, J. I., Agee, O. F., and Heilman, K. M.  Increased asymmetry of the planum temporale parallels improved phonological conceptual ability during childhood.  Society for Neuroscience Abstracts, 1994.

 

6.Breier, J. I., Gray, L., and Jahrsdoerfer, R. A. Accuracy and precision in horizontal localization after correction for congenital conductive hearing loss. Association for Research in Otolaryngology Abstracts 19:188, 1995.

 

7.Breier, J. I., Plenger, P. M., Wheless, J. W., Thomas, A. B., Brookshire, B. L., Willmore, L. J., and Papanicolaou,  A. C.  Differential effects of early onset seizure activity on figural and spatial memory in patients with temporal lobe epilepsy. Epilepsia 36:132, 1995.

 

8.Plenger, P. M., Breier, J. I., Wheless, J. W., Brookshire, B. L., Papanicolaou, A. C., Thomas, A. B., and Willmore, L. J. The Utility of the MMPI in differentiating non-epileptic seizure disorder from frontal lobe epilepsy.  Annual Meeting of the American Epilepsy Society, Baltimore, MD. Epilepsia 36:136, 1995.

 

9.Breier, J.I., Plenger, P.M., Wheless, J.W., Thomas, A.B., Brookshire, B.L., Curtis, V.L., Papanicolaou, A.C., Willmore, L.J. Evidence or re-organization of spatial and figural memory following early seizure activity. American Epilepsy Society, 1995.

 

10. Bauer, R. M., Breier J. I., Crosson, B., Gilmore, R., Fennell, E. B., and Roper, S.: Neuropsychological functioning before and after unilateral temporal lobectomy for intractable epilepsy.  Journal of the International Neuropsychological Society 1:362, 1995.

 

11. Gray, L., Breier, J. I., and Jahrsdoerfer, R. Localization of reverberant and anechoic virtual stimuli after correction for congenital conductive hearing losses. Association for Research in Otolaryngology Abstracts 19:188, 1995.

 

12. Breier, J. I., Plenger, P. M., Fuchs, K., Castillo, R., Wheless, J. W., Thomas, A. B., Brookshire, B. L., Willmore, L. J., and Papanicolaou, A. C.  Effects of temporal lobe epilepsy on spatial and figural aspects of memory for a complex geometric figure. 24th Annual Meeting of the International Neuropsychological Society, Chicago, IL, 1996; Journal of the International Neuropsychological Society 2:53, 1996.

 

13. Plenger, P.M., Breier, J.I., Willmore, L.J., Wheless, J.W., Thomas, A.B., Brookshire, B.L., Papanicolaou, A.C. Relationship of neuropsychological tests of frontal functioning to frontal lob seizures. Annual International Neuropsychological Society Meeting, Chicago, IL, 1996.

 

14. Breier, J. I., Thomas, A. B., Mullani, N., Plenger, P. M., Wheless, J. W.,   Papanicolaou, A.C., and Willmore, L. J.  Effects of age at onset and duration of chronic seizure disorder on asymmetries in temporal lobe metabolism and blood flow in complex partial epilepsy. Epilepsia 37 (Suppl. 5):1996. 

 

15. Brookshire, B. L., Breier, J. I., Fletcher, J. M., Plenger, P. M., Wheless, J. W., Thomas, A. B., Papanicolaou, A. C., and Willmore, L. J.  Cognitive profiles of adults with temporal lobe epilepsy and academic deficits.  Annual Meeting of the American Epilepsy Society, December, 1996; Epilepsia 37 (Suppl. 5):128, 1996.

 

16. Breier, J.I.; Thomas, A.B.; Mullani, N.; Plenger, P.M.; Wheless, J.W.; Papanicolaou, A.C.; Willmore, L.J. Effects of age at onset and duration of chronic seizure disorder on asymmetries in temporal lobe metabolism and blood flow in complex partial epilepsy. Poster presented at the Annual Meeting of the American Epilepsy Society, December 1996.

 

17. Brookshire, B.L.; Breier, J.I.; Fletcher, J.M.; Plenger, P.M.; Wheless, J.W.; Thomas, A.B.; Papanicolaou, A.; Willmore, L.J. Cognitive profiles of adults with temporal lobe epilepsy and academic deficits. Poster presented at the annual meeting of the American Epilepsy Society, December, 1996.

 

18. Plenger, P.M., Breier, J.I., Brookshire, B.L., Wheless, J.W., Thomas, A.B., Papanicolaou, A.C., and Willmore, L.J. Enhancing the discrimination of left temporal lobe epilepsy during the intracarotid sodium amobarbital procedure. Epilepsia 37 (Suppl. 5):133, 1996.

 

19. Breier, J. I., Brookshire, B. L., Fletcher, J. M., Plenger, P. M., Wheless, J. W., Thomas, A. B., Papanicolaou, A. C., and Willmore, L. J.  Identification of side of seizure onset in temporal lobe epilepsy using memory tests in the context of academic achievement deficit. Journal of the International Neuropsychological Society 3:9, 1997.  

 

20. Plenger, P. M., Breier, J. I., Mullani, N., Wheless, J. W., Thomas, A. B., Papanicolaou, A., and Willmore, L. J.  Asymmetries in frontal lobe glucose uptake and executive functions in temporal lobe epilepsy. Journal of the International Neuropsychological Society 3:73, 1997.

 

21. Fuchs, K., Breier, J. I., Brookshire, B. L., Wheless, J. W., Thomas, A .B., Papanicolaou, A. C., Willmore, L. J. The relationship between memory and language performance during the Intracarotid Amobarbital Procedure. Annual Meeting of the American Epilepsy Society; Boston, MA; December, 1997; Epilepsia 38 (Suppl. 8): 217-218, 1997.

 

22. Caudle, D.; Breier, J.I.; Brookshire, B.L.; Wheless, J.W.; Thomas, A.B.; Papanicolaou, A.; Willmore, L.J. MMPI profiles as a function of side of seizure operation in temporal lobe epilepsy. Journal of the International Neuropsychological Society 4(1):19, 1998.

 

23. Fuchs, K., Breier, J. I., Brookshire, B. L., Breier, J. I., Wheless, J. W., Thomas, A. B., Papanicolaou, A. C., and Willmore, L. J.  Language laterality affects Wada test performance.  Journal of the International Neuropsychological Society 4(1):73, 1998.

 

24. Papanicolaou, A.; Simos, P.; Breier, J.; Zouridakis, G. Language Mapping with Magnetoencephalography (MEG).   Journal of the International Neuropsychological Society 7:S211, 1998.

 

25. Papanicolaou, A. C., Simos, P., Breier, J. I., and Zouridakis G.  Language mapping with magnetoencephalography. Poster presented at the Annual International Meeting of the International Neuropsychological Society, July, 1998.

 

26. Zouridakis, G., Simos, P., Breier, J. I., and Papanicolaou, A. C.  Assessment of functional hemispheric asymmetries in a visual task using MEG. Paper presented at the 16th Annual Houston Conference on Biomedical Research. Houston, Texas, April 2 -3, 1998.

 

27. Kuldau, J. M., Leonard, C. M., Breier, J. I., Zuffante, P., Gautier, E. R., Heron, D. C., Laverv, E. M., Packing, J., Williams, S. A., and DeBose, C.  Cumulative effect of cerebral risk factors on the diagnosis of schizophrenia: An MRI study. Society of Neuroscience Abstracts, 1998.

 

28. Breier, J.I., Simos, P.G., Zouridakis, G., Papanicolaou, A.C. Reliability of MEG lateralization and localization of receptive language areas. 52nd Annual Meeting of the American Epilepsy Society; December 1998; Epilepsia 39 (Suppl. 6):143, 1998. 

 

29. Papanicolaou, A.C., Breier, J.I., Gormley, W.B., Simos, P.G., Wheless, J.W., Constantinou, J.E.C., and Willmore, L.J. Comparison of language mapping using extra- and intraoperative electrocortical stimulation and magnetoencephalography. Epilepsia 39 (Suppl. 6):107-108, 1998.

 

30. Wilson, M.E., Shelley, K.S., McMullen, M., Breier, J.I. People with epilepsy in the work place. Epilepsia 39 (Suppl. 6):238, 1998.

 

31. Willmore, L.J., Wheless, J.I., Breier, J.I., Kataki, M., Smith, J.R., King, D.W., Meador, J.K., Park, Y.D., and Loring, D.W. A comparison of magnetoencephalography (MEG), MRI, and V-EEG in patients evaluated for epilepsy surgery. Epilepsia 39 (Suppl. 6):64, 1998.

 

32. Simos, P.G., Breier, J.I., & Zouridakis, G. Papanicolaou, A.C. Identification of language-related brain activity using magnetoencephalography. 11th International Conference on Biomagnetism, Biomag98, Sendai Japan, August 28-September 2, 1998. 

 

33. Zouridakis, G., Simos, P.G., Breier, J.I., & Papanicolaou, A.C. Cerebral dominance assessment using magnetoencephalography. 11th International Conference on Biomagnetism, Biomag98, Sendai Japan August 28-September 2, 1998.

 

34. Papanicolaou, A.C., Simos, P.G., Breier, J.I., & Zouridakis, G. Mapping of Language specific cortex with MEG.  11th International Conference on Biomagnetism, Biomag98, Sendai, Japan August 28-September 2, 1998.

 

35. Zouridakis G., Simos P.G., Breier J.I., and Papanicolaou A.C. “Assessment of Functional Hemispheric Asymmetries in a Visual Language Task via MEG.” Biomag98, P-IX-35, p230, 1998.

 

36. Papanicolaou, A.C., Simos, P.G., Breier, J.I., & Zouridakis, G. Language mapping with magnetoencephalography (MEG). Neuroimage, 7, S178, 1998.

 

37. Papanicolaou, A.C., Simos, P.G., Breier, J.I., & Zouridakis, G. Language mapping with magnetoencephalography. Fourth International Conference on Functional Mapping of the Human Brain, June 1998.

 

38. Maggio W.W., Simos P.G., Breier J.I., Zouridakis G., Gormley W.B., Constantinou J.E.C., Wheless J.W., Papanicolaou A.C. Magnetic Source Imaging Speech Mapping: Comparison with Intraoperative Speech Mapping. Rocky Mountain Association Meeting, 1999.

 

39. Simos, P.G., Breier, J.I., Zouridakis, G., Papanicolaou, A.C. MEG correlates of categorical perception of temporal cues for voicing in humans. Journal of the International Neuropsychological Society, 5: S135, 1999.

 

40. Breier, J.I., Simos, P.G., Zouridakis, G., & Papanicolaou, A.C. Timing of neuronal activity in distinct areas of the brain during a verbal recognition memory task. Journal of International Neuropsychology Society 5:153, 1999.

 

41. Wright, M., Breier, J.I., Wheless, J.W., Constantinou, J.E.C., and Willmore, L.J. Anxiety and conversion symptoms in adolescent pseudoseizures. Journal of International Neuropsychology Society 5:135, 1999.

 

42. Simos, P.G., Breier, J.I., Zouridakis, G., & Papanicolaou, A.C. MEG correlates of categorical perception of temporal cues for voicing in humans. Paper presented at the February 1999 International Neuropsychological Society Meeting. Journal of International Neuropsychology Society 5:125-126, 1999.

 

43. Breier, J.I., Zouridakis, G., Simos, P.G., & Papanicolaou, A.C. Timing of Activity in Distinct Brain Areas During a Recognition Memory Task for Words. Paper presented at the 17th Annual Houston Conference on Biomedical Engineering Research, February 10-13, 1999, Houston, Texas.

 

44. Papanicolaou, A.C., Simos, P., Breier, J., Zouridakis, G. MEG-Derived Maps of Language-Specific Cortex. 27th Annual Meeting of the International Neuropsychological Society; Boston, Massachusetts; February 10-13, 1999.

 

45. Zouridakis, G., Simos, P.G., Breier, J.I., Gormley, W.B., Wheless, J.W., Constantinou, J.E.C. & Papanicolaou, A.C. Language Mapping via Magnetoencephalography. Paper presented at the 17th Annual Houston Conference on Biomedical Engineering Research, February 10-13, 1999, Houston, Texas. 

 

46. Papanicolaou, A.C., Zouridakis, G., Simos, P., Breier, J.I., Maggio, W.W., Gormley, W.B., Constantinou, J.E.C., Wheless, J., Willmore, L.J., Kramer, L.A. Comparison of MSI and Invasive Brain Mapping Procedures: Normative and Clinical Studies of Language. 5th International Conference on Functional Mapping of the Human Brain. Dusseldorf, Germany; June 22-26, 1999.

 

47. Papanicolaou, A.C., Simos, P., Zouridakis, G., Breier, J.I., Gormley, W.B., Constantinou, J.E., Wheless, J.W., Maggio, W.W. Applications of MEG to the Mapping of the Language Cortex. 2nd Annual Symposium on Non-Invasive Functional Source Imaging. Dubrovnik, Croatia; September 3-7, 1999.

 

48. Papanicolaou, A.C., Simos, P.G., Zouridakis, G., Breier, J.I., Gormley, W.B. Constantinou, J.E., Wheless, J.W., & Maggio, W.W. Mapping the language cortex with MSI. 23rd Annual International Epilepsy Congress; September 12-17, 1999; Prague, Czech Republic.

 

49. Maggio, W.W. Simos, P.G., Breier, J.I., Zouridakis, G., Gormley, W.B. Constantinou, J.E., Wheless, J.W., & Papanicolaou, A.C. Speech mapping with MSI: Comparison with intraoperative speech mapping. 23rd Annual International Epilepsy Congress; September 12-17, 1999; Prague, Czech Republic.

 

50. Papanicolaou, A.C., Simos, P.G., Zouridakis, G., Breier, J.I., Gormley, W.B., Constantinou, J.E., Wheless, J.W., Maggio, W.W. Mapping the Receptive Language Cortex. 1999 Annual Meeting, Society for Neuroscience, October 23-28, 1999.  Society for Neuroscience Abstracts, 25(2): 1635, 1999.

 

51. Simos, P.G., Breier, J.I., Fletcher, J.M., & Papanicolaou, A.C. Failure to engage brain areas involved in phonological decoding in dyslexic children: A magnetic source imaging study.  Society for Neuroscience Abstracts, 25(2): 2170, 1999.

 

52. Papanicolaou, A.C., Simos, P.G., Breier, J.I., Zouridakis, G., Constantinou, J.E., Wheless, J.W., Maggio, W.W. Applications of MEG to the mapping of the language cortex. 53rd Annual Meeting of the American Epilepsy Society; Orlando, Florida; December 3-9, 1999.

 

53. Simos, P.G., Fletcher, J., Breier, J.L., Berman, E., Zouridakis, G., Papanicolaou, A.C. Failure to Engage Brain Areas Involved in Phonological Access in Dyslexia: A Magnetic Source Imaging study. 1999 Annual Meeting, Society for Neuroscience, October 23-28, 1999.  Society of Neuroscience Abstracts, 25(2): 2170, 1999. 

 

54. Papanicolaou, A.C., Simos, P.G., Breier, J.I., Zouridakis, G., Constantinou, J.E., Wheless, J.W., & Maggio, W.W. Applications of MEG to the mapping of language specific cortex. Abstract presented at the 53rd Annual Meeting of the American Epilepsy Society, December 3-9, 1999.  Epilepsia 40(7): 178, 1999.

 

55. Breier, J.I., Clark, A., Cass, J. Wheless, J.W., Constantinou, J.E.C. Profiles of cognitive performance in TLE patients with and without learning disability. Abstract presented at the 53rd Annual Meeting of the American Epilepsy Society, December 3-9, 1999.  Epilepsia 40(7): 47, 1999.

 

56. Maggio, W.W., Simos, P.G., Breier, J.I., Zouridakis, G., Gormley, W.B., Constantinou, J.E.C., Wheless, J.W., Papanicolaou, A.C. Speech Mapping with Magnetic Source Imaging: Comparison with Intraoperative Speech Mapping. Epilepsia 40 (Suppl. 2): 50, 1999.

 

57. Breier, J., Clark, A., Cass, J., Wheless, J., Constantinou, J.E.  Profiles of Cognitive Performance in TLE Patients With and Without Learning Disability.  Epilepsia.  40(Suppl. 7):  47, 1999.

 

58. Papanicolaou, A.C., Simos, P.G., Zouridakis, G., Breier, J.I, Gormley, W.B., Constantinou, J.E., Wheless, J.W., Maggio, W.W. Mapping the Language Cortex with MSI. Epilepsia 40 (Suppl. 2): 50-51, 1999.

 

59. Maggio, W.W.; Simos, P.G.; Breier, J.I.; Zouridakis, G.; Gormley, W.B.; Constantinou, J.E.C.; Wheless, J.W.; Papanicolaou, A.C. Magnetic Source Imaging Speech Mapping: Comparison with Intraoperative Speech Mapping. Paper presented at the annual meeting of the Rocky Mountain Association, 1999.

 

60. Simos, P.G., Breier, J.I., Fletcher, J.M., Foorman, B.R., Bergman, E., & Papanicolaou, A.C. Consistent failure to engage brain areas involved in phonological decoding in dyslexia: A magnetic source imaging study of two consecutive series in children. Journal of the International Neuropsychological Society, 6:211, 2000.

 

61. Breier, J., Clark, A., Cass, J., Fletcher, J., Brookshire, B., Wheless, J., Constantinou, J.  Specific Reading Disability in Temporal Lobe Epilepsy and Reorganization of Language Function.  Journal of the Neuropsychological Society. 6(Suppl. 2): 197, February, 2000.

 

62. Simos, P., Breier, J., Fletcher, J., Foorman, E., Bergman, E., Papanicolaou, A.C.  Consistent Failure to Engage Brain Areas Involved in Phonological Decoding in Dyslexia:  A Magnetic Source Imaging Study of Two Consecutive Series of Children.  Journal of the Neuropsychological Society. 6(Suppl. 2):  211, February, 2000.

 

63. Papanicolaou, A.C., Simos, P.G., Breier, J.I., Zouridakis, G., Constantinou, J.E., Wheless, J.W., Maggio, W.W.  Applications of MEG to the Mapping of the Language-Specific Cortex.  Epilepsia.  40(Suppl. 7): 179, 2000.

 

64. Maggio, W.W., Simos, P.G., Breier, J.I., Zouridakis, G., Gormley, W.B., Constantinou, J., Wheless, J.W., Papanicolaou, A.C.  Magnetic Source Imaging Speech Mapping:  Comparison with Interoperative Speech Mapping.  Epilepsia.  40(Suppl. 7):  181, 2000.

 

65. Simos, P.G., Breier, J.I., Fletcher, J.M., Foorman, B.R., Bergman, E., Papanicolaou, A.C. Consistent failure to engage brain areas involved in phonological coding in dyslexia: A Magnetic Source Imaging study of two consecutive series of children (submitted). 28th Annual Meeting of the International Neuropsychological Society; Denver, Colorado; February 9-12, 2000.

 

66. Simos, P.G., Breier, J.I., Wheless, J.W., Maggio, W.W., Papanicolaou, A.C. Mechanisms for Reading Words and Pseudowords: Insights from Functional Imaging and Electrocortical Stimulation (submitted). 23rd Mid Year Annual Meeting of the International Neuropsychological Society; Brussels, Belgium; July 12-15, 2000.

 

67. Simos, P.G.; Breier, J.I.; Fletcher, J.M.; Foorman, B.R.; Mouzake, A.; Papanicolaou, A.C. Age-related Changes in Regional Brain Activation During Phonological Decoding and Printed Word Recognition (submitted). 23rd Mid Year Annual Meeting of the International Neuropsychological Society; Brussels, Belgium; July 12-15, 2000.

 

68. Breier, J.I., Wheless, J.W., Simos, P.G., Constantinou, J.E.C., Baumgarter, J.E., Venkatarman, V., & Papanicolaou, A.C. Language dominance in children as determined by magnetic source imaging and the intracarotid amobarbital procedure: A comparison. Paper presented at the 29th Annual Meeting of the Child Neurology Society. St. Louis, MO, October 25 – 28, 2000.

 

69. Castillo, E.M., Simos, P.G., Fletcher, J.M., Francis, D.J., Maestu, F., Breier, J.I. Ph.D., Maggio, W.W., Papanicolaou, A.C. Mapping of receptive language in Bilinguals using Magnetic Source Imaging. Poster presented at the annual Session at the Neuroscience Research Center, University of Texas Medical School/Houston, Houston, Texas, December 2, 2000.

 

70. Wheless, J.W., Breier, J.I., Simos, P.G., Constantinou, J.E.C., Baumgarter, J.E., Venkatarman, V., & Papanicolaou, A.C. A comparison of language dominance in children as determined by magnetic source imaging and the intracarotid amobarbital procedure. Epilepsia.  41(Suppl. 7): 81, 2000.

 

71. Breier, J.I., Gray, L., Klaas, P., Fletcher, J.M., Foorman, B. Dissociation of sensitivity and response bias in children with ADHD during central auditory masking. Paper presented at the annual meeting of the Association for Research in Otolaryngology. Orlando, FL. Feb 4 – 11, 2001.

 

72. Castillo, E.M., Davis, R.N., Simos, P.G., Breier, J.I., and Papanicolaou, A.C. Is the Left Superior Temporal Gyrus Specialized for Speech Processing? An Investigation Using Magnetoencephalography. Nineteenth Annual Houston Conference on Biomedical Engineering Research, February 8-9, 2001.

73. Papanicolaou, A.C., Simos, P.G., Breier, J.I., Wheless, J.W., and Maggio, W.W. Mechanisms for reading words and pseudowords: Insights from functional imaging and electrocortical stimulation. Journal of the International Neuropsychological Society 6:213, 2001.

 

74. Papanicolaou, A.C., Simos, P.G., Breier, J.I., Fletcher, J.M., Foorman, B.R., and Mouzaki, A. Age-related changes in regional brain activation during phonological decoding and printed word recognition. Journal of the International Neuropsychological Society 6:103, 2001.

 

75. Davis, R.N., Castillo, E.M., Simos, P.G., Breier, J.I., and Papanicolaou, A.C.  Mapping of   Receptive Language Cortex in English-Spanish Bilinguals Using Magnetoencephalography. Nineteenth Annual Houston Conference on Biomedical Engineering Research, February 8-9, 2001.

 

76. Davis, R.N., Castillo, E.M., Simos, P.G., Breier, J.I., and Papanicolaou, A.C. Language mapping using MSI: An overview poster presented at the Sixth Annual Public Forum for Brain Awareness Week,  Houston, TX.  March, 2001.

 

77. Papanicolaou, A.C., Simos, P.G., Breier, J.I., Castillo, E.M., Davis, R.N., Wheless, J. W., Venkataraman, V., Kim, H.L., and Maggio, W.W.  MEG:  A method comparable to the Wada procedure for language laterality assessment.  Epilepsia 42 (Suppl. 7):75, 2001.

 

78. Gray, L., & and Breier, J. Development of perceptual dimensions lags the ability to perceive details. Journal of the Acoustical Society of America. (In press).

 

79. Ishibashi, H., Simos, P.G., Castillo, E.M., Maggio, W.W., Wheless, J.W., Kim, H.L., Venkataraman, V., Sanders, D.K., Breier, J.I., Zhang, W., Davis, R.N., and Papanicolaou, A.C.  Detection and significance of focal, interictal slow wave activity for localization of the primary epileptogenic region using Magnetoencephalography.  Epilepsia 42 (Suppl. 7):272, 2001.

 

80. Breier, J.I., Gray, L., Klaas, P., Fletcher, J.M., Foorman, B. Auditory temporal processing in children with dyslexia with and without attention deficit/hyperactivity disorder. Paper presented at the annual meeting of the Association for Research in Otolaryngology. Orlando, FL. Feb 4 – 11, 2002.

 

81. Castillo, E., Davis, R., Simos, P.G., Breier, J.I., Fitzgerald, M., Ishibashi, H., Zhang, W. & Papanicolaou, A.C. Two brain mechanisms mediating different levels of word processing and memory performance. Journal of the International Neuropsychological Society 8: 163, 2002.

 

82. Papanicolaou, A.C., Simos, P.G., Breier, J.I., Castillo, E., & Davis, R. Language mapping with magnetoencephalography (MEG) yields results comparable to the Wada test. Journal f the International Neuropsychological Society 8: 216-217, 2002.

 

83. Castillo, E., Davis, R., Simos, P.G., Breier, J.I., Fitzgerald, M., Ishibashi, H., Zhang, W. & Papanicolaou, A.C. Dynamics of activation in medial temporal lobe structures during encoding and recognition. Journal of the International Neuropsychological Society 8: 227, 2002.

 

84. Zhang W., MD, PhD, Simos, P.G., MD, PhD, Ishibashi, H., MD, PhD, Castillo E.M., PhD, Breier J, PhD, Baumgartner, J.E, MD, Wheless, J.W., MD, Papanicolaou A.C. PhD. Neuroimaging Features of Epidermal Nevus Syndrome, ASNR(American Society of Neuroradiology) 40th Annual Meeting,  Vancouver, Canada, May 13-17, 2002

 

87. Zhang W., MD, PhD, Simos, P.G., MD, PhD, Ishibashi, H., MD, PhD, Wheless, J.W., MD, Maggio, W.W., MD, Castillo E.M., PhD, Baumgartner, J.E, MD, Breier J, PhD, Papanicolaou A.C. PhD. MEG assists in finding subtle cortical dysplasia.  Epilepsia 43: 78, 2002.

 

88. Breier, J.I., Fletcher, J.M., Foorman, B., Gray, L. Perceptual maps of a voice onset time series in children at risk for dyslexia. Paper to be presented at the 34th annual meeting of the International Neuropsychological Society, Hawaii, USA. Dec 4 – 7, 2002.

 

89. Papanicolaou, A.C., Simos, P.G., Castillo, E.M., Breier, J.I., Wheless, J.W., Maggio, V., Billingsley, R.L., Sarkari, S., Pataraia, E., Clear, T., Maggio, W.W. MEG is comparable to the Wada procedure for language laterality assessment. Epilepsia, 44(Suppl. 9): 251-252, 2003. Paper presented at the Annual meeting of the American Epilepsy Society, Boston, MA., Dec. 5 – 10.

 

90. Pataraia, E., Simos, P.G., Billingsley, R.L., Castillo, E.M., Sarkari, S., Maggio, V., Wheless, J.W., Fitzgerald, M., Breier, J.I., Papanicolaou, A.C. Contribution of magnetoencephalography to the presurgical determination of the epileptogenic zone in patients with frontal lobe epilepsy. Epilepsia, 44(Suppl. 9): 252, 2003. Paper presented at the Annual meeting of the American Epilepsy Society, Boston, MA., Dec. 5 – 10.

 

91. Castillo, E.M., Simos, P.G., Breier, J.I., Wheless, J.W., Butler, I.J., Billingsley, R.L., Papanicolaou, A.C. Epileptic activity interfering with word processing in landau-kleffer syndrome: the role of the non-affected hemisphere in linguistic deficit manifestation. Paper to be presented at the Annual meeting of the American Epilepsy Society, Boston, MA., Dec. 5 – 10.

 

92. Davis, R. N., Witgert, M. E., & Breier, J. I.  Is basic memory structure invariant across epilepsy patient subgroups? Paper presented at the International Neuropsychological Society 37th Annual Meeting, Baltimore, MD., Feb. 4-7, 2004.

 

93. Davis, R. N., Cole Davis, L., & Breier, J. I. Predicting side of epileptic focus using actuarial vs. clinical prediction: A preliminary comparison. Poster presented at the International Neuropsychological Society 37th Annual Meeting, Baltimore, MD., Feb. 4-7, 2004.

 

94. Castillo, E.M., Breier, J.I., Wheless, J.W., Pataraia, E., Papanicolaou, A.C.  Planning epilepsy surgery when language is compromised: comparisons of MEG-derived maps of activation with the Wada test and with direct electrical stimulation mapping.  6th European Congress on Epileptogology.  Vienna, Oral presentation platform.  May30th – June 3rd, 2004.

 

95. Castillo, E.M., Simos, P.G., Wheless, J.W., Baumgartner, J.E., Breier, J.I., Sarkari, S., Fitzgerald, M.E., Papanicolaou, A.C.  Mapping sensorimotor function in patients with perirolandic lesions: a comprehensive MEG protocol.  14th International Conference on Biomagnetism, Boston, August 8-12, 2004.

 

96. Pataraia, E., Castillo, E.M., Simos, P.G., Billingsley-Marshall, R.L., Sarkari, S., Breier, J.I., Papanicolaou, A.C. Relative merits of MEG for identification of the epileptogenic zone as compared with invasive EEG. 14th International Conference on Biomagnetism, Boston, August 8-12, 2004.

 

97. Castillo, E.M., Breier, J.I., Wheless, J.W., Baumgartner, J.E., Pataraia, E., Papanicolaou, A.C.  Is linguistic function still there after multiple subpial transactions over Wernicke’s area?  American Epilepsy Society, 58th Annual Meeting, New Orleans, December 3-8, 2004.

 

98.  Perkins, F.F., Clarke, D.F., Breier, J.I., Chacon, M.M., Castillo, E.M., Weers, D., Wheless, J.W.  Benign Rolandic Epilepsy: Neuropsychological Testing and Magnetic Source Imaging Analysis.  American Epilepsy Society, 58th Annual Meeting, New Orleans, December 5-8, 2004. 

 

99.  Breier, J.I., Simos, P.G., Castillo, E.M., Pataraia, E., Billingsley, R.L., Wheless, J.W., and Papanicolaou, A.C.  Abnormal Activation of Language Cortex in Patients With Chronic Seizures and Academic Achievement Deficit.  American Epilepsy Society, 58th Annual Meeting, New Orleans, December 5-8, 2004. 

 

100.  Pataraia, E., Billingsley-Marshall, R.L., Castillo, E.M., Breier, J.I., Simos, P.G., Sarkari, S., Fitzgerald, M., Clear, T., and Papanicolaou, A.C.  Organization of Receptive Language-Specific Cortex Before and After Left Temporal Lobectomy. American Epilepsy Society, 58th Annual Meeting, New Orleans, December 5-8, 2004.

 

101. Castillo, E.M., Breier, J.I., Wheless, J.W., Slater, J.D., Tandon, N., Baumgartner, J.E., McManis, M.H., Papanicolaou, A.C. Contributions of Direct Cortical Stimulation and MEG Recordings to Identify “Essential” Language Cortex. American Epilepsy Society and American Clinical Neuropsychology Society Joint Annual Meeting, Washington, DC, December 206, 2005.

 

102. Pataraia, E., Simos, P.G., Billingsley-Marshall, R.L., Castillo, E.M., Breier, J.I., Sarkari, S., Papanicolaou, A.C. Assessment of the Localization Accuracy of Magnetoencephalography in Temporal Lobe Epilepsy – Comparison with Invasive EEG. American Epilepsy Society and American Clinical Neurophysiology Society Joint Annual Meeting, Washington DC, December 2-6, 2005.

 

103. Slater, J.D., McManis, M.H., Clarke, D., Perkins, F.F., McGregor, A.L., Wheless, J.W., Breier, J.I., Castillo, E.M., Papanicolaou, A.C. Magnetic Source Localization in Patients with Idiopathic Generalized Epilepsies. American Epilepsy Society and American Clinical Neurophysiology Society Joint Annual Meeting, Washington DC, December 2-6, 2005.

 

104. Breier, J. I., Maher, L., Castillo, E. M., Novak, B., Papanicolaou, A. Neurophysiological Changes in Receptive Language Cortex with Age Using Magnetoencephalograpgy. Journal of the International Neuropsychological Society (in press).

 

 

 

Referred Original Articles in Journals:

 

1.Breitmeyer, B. G., and Breier, J. I. Effects of background color on reaction time to stimuli varying in size and contrast: inferences about human M channels. Vision Res. 34:1039-1045, 1994.

 

2.Breier, J. I., Adair, J., Fennell, E. B., Gold. M., Gilmore, R., and Heilman, K. M. Dissociation of anosognosia for hemiplegia and aphasia during left hemisphere anesthesia. Neurology 45:65-67, 1995.

 

3.Breier, J. I., Plenger, P. M., Wheless, J. W., Thomas, A. B., Brookshire, B. L., Curtis, V. L., Willmore, L. J., Papanicolaou, A. C., and Clifton, G. L.  Memory tests distinguish between patients with focal temporal and extra-temporal lobe epilepsy. Epilepsia 37:165-170, 1996.

 

4.Breier, J. I., Leonard, C. M., Bauer, R. M., Roper, S., and Gilmore, R. Quantified volumes of temporal lobe structures in patients with epilepsy.  Journal of Neuroimaging 6:108-114, 1996.

 

5.Plenger, P. M., Breier, J. I., Wheless, J. W., Brookshire, B. L., Papanicolaou, A. C., Thomas, A. B., and Willmore, L. J. The nonverbal selective reminding test: Efficacy in the assessment of adults with temporal lobe epilepsy.  Journal of Epilepsy 9:65-69, 1995.

 

6.Leonard, C. M., Lombardino, L. J., Mercado, L., Browd, S. R., Breier, J. I., and Agee, O. F. Cerebral asymmetry and cognitive development in children: a magnetic resonance imaging study.  Psychological Science. 7:89-95, 1996.

 

7.Breier, J. I., Dede, D., Fiano, K., Fennell, E., Leach, L., Uthman, B., and Gilmore, R. Evidence for differential lateralization of languages in a bilingual speaker during the Wada procedure. Neurocase 2:341-345, 1996.

 

8.Breier, J. I., Plenger, P. M., Fuchs, K., Castillo, R., Wheless, J. W., Thomas, A. B., Brookshire, B. L., Willmore, L. J., and Papanicolaou, A. C. Effects of temporal lobe epilepsy on spatial and figural memory for a complex geometric figure.  Journal of the International Neuropsychological Society 2:535-540, 1996.

 

9.Plenger, P. M., Breier, J. I., Wheless, J. W., Brookshire, B. L., Papanicolaou, A. C., and Willmore, L. J. Lateralization of memory for music: Evidence from the intracarotid sodium amobarbital procedure. Neuropsychologia 34:1015-1018, 1996.

 

10. Breier, J. I., Brookshire, B. L., Fletcher, J. M., Plenger, P. M., Wheless, J. W., Thomas, A.B., Papanicolaou, A. C., and Willmore, L. J. Identification of side of seizure onset in temporal lobe epilepsy using memory tests in the context of academic achievement deficit. Journal of Clinical and Experimental Neuropsychology 19:161-171, 1997.

 

11. Breier, J. I., Mullani, N., Thomas, A. B., Plenger, P. M., Wheless, J. W., Papanicolaou, A.C., and Willmore, L. J.  Effects of duration of epilepsy on the uncoupling of metabolism and blood flow in complex partial seizures. Neurology 48:1047-1053, 1997.

 

12. Breier, J. I., Thomas, A. B., Plenger, P. M., Wheless, J. W., Brookshire, B. L., Papanicolaou, A. C., and Willmore, L. J. Asymmetries in the effect of side of seizure onset on recognition memory following intracarotid amobarbital injection. Epilepsia 38:1209-1215, 1997.

 

13. Breier, J. I., Gray, L., Hiscock, M., and Jahrsdoerfer, R.  Dichotic listening after correction of congenital hearing loss: Evidence for a critical period in the establishment of ear advantage. Neuropsychologia 36:209-216, 1998.

 

14. Simos, P. G., Breier, J. I., Zouridakis, G., and Papanicolaou, A. C. Magnetic Fields elicited by a tone onset time continuum in humans. Cognitive Brain Research 6:285-294, 1998.