Kathleen Haaland
University of New Mexico School of Medicine
Albuquerque, NM
No Prerequisites—Course will be taught on a graduate level
I. Hemispheric Control of Skilled Movement
A. Strict contralateral control
B. Bilateral control from either hemisphere
C. Bilateral control primarily from the left hemisphere
D. Bilateral control primarily from the right hemisphere
II. Intrahemispheric Control of Skilled Movement: Cortical and subcortical influences
III. Limb Apraxia
A. Different forms of apraxia
B. Left Hemisphere Dominance
C. Assessment
D. Neuroanatomical correlates: Cortical and subcortical regions
E. Functional Implications
IV. Motor Sequencing
A. Cognitive Mechanisms: Response organization, response selection and retrieval, and timing
B. Left hemisphere Dominance: Cognitive mechanisms and neuroanatomical correlates based on data in focal lesion stroke and Parkinson’s Disease patients and functional imaging studies
C. Intrahemispheric Control: Roles of the left frontal and parietal lobes
* Required, others optional
2. Harrington,
D.L. and Haaland, K.Y. Sequencing in Parkinson's disease:
Abnormalities in programming and controlling movement. Brain,
114: 99 115, 1991.
3. * Harrington, D.L. and Haaland, K.Y. Motor
sequencing deficits with left hemisphere damage: Are some
cognitive deficits specific to limb apraxia? Brain, 115: 857 874,
1992.
4. * Rao, S.M., Harrington, D.L., Haaland, K.Y., et
al. Distributed neural systems underlying the timing of movements.
Journal of Neuroscience. 17, 5528-5535, 1997.
5. Harrington, D.L., Haaland, K.Y., &
Hermanowicz, N. Temporal processing in the basal ganglia.
Neuropsychology, 12, 3-12, 1998.
6. Haaland, K.Y., Harrington, D.L., Knight, R.T.
Spatial deficits in ideomotor limb apraxia: A kinematic analysis
of
aiming movements. Brain, 122, 1169-1182, 1999.
7. * Haaland, K.Y., Harrington, D.L., Knight, R.T.
Neural representations of skilled movement. Brain, 123, 2306-2313, 2000.
8. Hamilton, J.M., Haaland, K.Y., Adair, J.C.,
Brandt, J. Ideomotor limb apraxia in Huntington’s Disease: Implications
for corticostriate involvement. Neuropsychologia, 41, 1-8, 2003.
9. * Haaland, K.Y., Elsinger, C., Mayer, A.,
Durgerian, S., Rao, S. Motor sequence complexity and performing
hand produce differential patterns of hemispheric lateralization,
Journal of Cognitive Neuroscience, In Press.
10. Kakei, S., Hoffman, D. S., Strick, P. L. (1999).
Muscle and movement representations in the primary motor cortex.
Science,
285, 2136-2139.
11. * Karni, A., Meyer, G., Jezzard, P., Adams, M. M.,
Turner, R., & Ungerleider, L. G. (1995). Functional MRI evidence
for adult
motor cortex plasticity during motor skill learning. Nature, 377,
155-158.
12. Moll, J., Oliveira-Souza, R., Passman, L. J.,
Cimini Cunha, F., Souze-Lima, F., & Ardreiuolo, P. A. (2000).
Functional MRI correlates of real and imagined tool-use pantomimes.
Neurology, 54, 1331-1336
13. * Muellbacher, W., Ziemann, U., Wissel, J.,
Dang, N., Kofler, M., Facchini, S. et al. (2002). Early consolidation
in human primary motor cortex. Nature, 415, 640-644.
14. Petrides, M. & Pandya, D. N. (1984).
Projections to the frontal cortex from the posterior parietal region in
the rhesus monkey. Journal of Comparative Neurology, 228, 105-116.
15. Rushworth, M. F., Paus, T., & Sipila, P. K.
(2001). Attention systems and the organization of the human parietal
cortex. J.Neurosci., 21, 5262-5271.Shadmehr, R. & Holcomb, H. H.
(1997). Neural correlates of motor memory consolidation. Science, 277,
821-825.
16. * Schluter ND, Krams M, Rushworth MF, Passingham
RE. Cerebral dominance for action in the human brain: the selection of
actions. Neuropsychologia 2001; 39: 105-113.
17. Schluter ND, Rushworth MFS, Passingham R, Mills
KR. Temporary interference in human lateral premotor cortex suggests
dominance for the selection of movements. Brain 1998; 121: 785-799.
Reviews
1. Goodale, M. A. & Milner, A. D. (1992). Separate
visual pathways for perception and action. Trends in Neuroscience, 15,
35-62.
2. * Haaland, K.Y. and Harrington, D.L. Hemispheric asymmetry of
movement. Current Opinion in Neurobiology, 6: 796-800, 1996.
3. * Kalaska JF, Scott S, Cisek P, Sergio LE. Cortical control of
reaching movements. Curr Opin Neurobiol 1997; 7: 849-859.
4. * Koski, L., Iacoboni, M., & Mazziotta, J. C. (2002).
Deconstructing apraxia: understanding disorders of intentional movement
after
stroke. Curr.Opin.Neurol., 15, 71-77.
5. * Rizzolatti, G., Luppino, M., & Matelli, M. (1998).
The organization of the cortical motor system: New concepts.
Electroencephalography and Clinical Neurophysiology, 106, 283-296.