Cell Biology of Generative and Regressive Events in the
Central Nervous System Across Life-Span
Lazaros Triarhou, Ph.D.
University of Macedonia, Greece
Introductory
Neuroscience, Cell Biology
Course
Description:
The topics
that will be covered include: 1) Cell biology of neural development:
Fundamental principles of neurogenesis, synaptogenesis and epigenesis. 2)
Mammalian C.N.S. development and plasticity: Clues from neurological mutations
in the laboratory mouse. 3) Deciphering mechanisms of neuron loss in
degenerative phenotypes through cell count analyses: Toward a 'Mathematical
Neuropathology'. 4) Nervous tissue transplantation and regeneration in
development and adulthood.
Reading List
BOOKS
Gray F, De Girolami U, Poirier J (2004) Escourolle and Poirier Manual of
Basic Neuropathology, 4th edn. Butterworth-Heinemann,
Triarhou LC (2002) Dopaminergic Neuron Transplantation in the Weaver
Mouse Model of Parkinson’s Disease. (Advances in Experimental
Biology and Medicine, vol. 517).
ARTICLES
Clarke G, Lumsden CJ (2005) Heterogeneous cellular environments modulate one-hit neuronal death kinetics. Brain Research Bulletin 65: 59-67
Sotelo C (1980) Mutant mice and the
formation of cerebellar circuitry. Trends in
Neurosciences 3: 33-36
Triarhou, L.C. (1998) Rate of neuronal fallout in a transsynaptic
cerebellar model. Brain Research Bulletin 47: 219-222