Timothy King

Ph.D. Focus: Tissue Engineering (Biophysics)

Thesis Title: Enhanced In Vivo Angiogenesis Within A Model Tissue Engineered Construct Using Biodegradable Microspheres Containing Encapsulated VEGF Click here for abstract

Thesis Advisor: Charles Patrick, Jr., Ph.D., M.D. Anderson

Alumnus - June 2001

I received my bachelors and masters degrees in bioengineering from Texas A&M University in 1991 and 1993 respectively. My masters degree thesis was the development of a non-invasive optical glucose monitor utilizing the Pockel's effect for diabetic home monitoring. The device, if brought to market, would measure the glucose concentration in the anterior chamber of the eye using multispectral laser light and correlate it to the blood glucose concentration.

I completed my Ph.D. in the Reparative Biology and Bioengineering Laboratory in the Department of Plastic Surgery at M.D. Anderson Cancer Center under the advisment of Charles Patrick, Jr., PhD. My Ph.D. thesis is in the field of Tissue Engineering. Specifically, my project involved the in vivo investigation of neovascularization using microspheres with encapsulated VEGF in a model tissue engineered construct. For more information, click here to see the abstract from my PhD defense, or click here to go to my webpage where you can read a copy of my dissertation and see a movie of a microsphere produced using the manufacturing technique I invented (patent pending).

I am currently in the combined Plastic Surgery program at NYU. The program consists of three years of general surgery followed by three years of plastic surgery. My long-term career goals are to combine plastic and reconstructive surgery with tissue engineering for the treatment of tissue deficiencies and improvement of wound healing.

When I am not in the hospital, I am usually with my best friend and wife, Christy Tock. We like camping, hiking, and just about anything else involving the outdoors. I also like photography, cooking, and fooling around with computers. (I used to maintain this web site!) If you have any questions, please feel free to email me at twk@writeme.com.
 

Curriculum Vitae

Education

B.S. Bioengineering - Texas A&M University, 1991
M.S. Bioengineering - Texas A&M University, 1993
Ph.D. University of Texas Houston Graduate School of Biomedical Sciences, 2000
M.D. University of Texas Medical School - Houston, 2001

Residency & Fellowships

Residency: Plastic Surgery - New York University, New York, NY, 2001-2007

Publications

King TW, Tock CL, Chauvin PB, Johnston C, Patrick Jr. CW. VEGF-encapsulated biodegradable microspheres enhance in vivoangiogenesis within a model tissue engineered construct. Submitted for review.

King TW, Tock CL, Chauvin PB, Reece GR, Johnston C, Patrick Jr. CW. VEGF-impregnated fibrin gel enhances in vivo angiogenesis within a model tissue engineered construct. Submitted for review.

King TW, Gallas MT, Chen VY, Ramos M, Lalani Z, Miller MJ. Flap Selection for Optimal Functional and Aesthetic Outcome in Posterior Mandible Reconstruction. Submitted for review.

King TW, Brey E, Youssef A, Johnston C, Patrick Jr. CW. Quantification of vascular density using a semi-automated technique for immuno-stained specimens. Submitted for review.

King TW, Patrick Jr. CW. Development and In VitroCharacterization of Vascular Endothelial Growth Factor (VEGF)-Loaded Poly(DL-Lactic-Co-Glycolic Acid)/Poly(Ethylene Glycol) Microspheres Using a Solid Encapsulation/Single Emulsion/Solvent Extraction Technique. Journal of Biomedical Materials Research.51(3): 383-390, September 5, 2000. Selected as Journal Cover Article/Photograph.

Bick RJ, Liao JP, King TW, LeMaistre A, McMillin JB, Buja LM. Temporal Effects of Cytokines on Neonatal Cardiac Myocyte Ca²⁺ Transients and Adenylate Cyclase Activity. American Journal of Physiology - Heart & Circulatory Physiology.41(4): H1937-H1944, April 1997.

King TW, Coté GL, McNichols R, Goetz, Jr. MJ. Multispectral Polarimetric Glucose Detection Using a Single Pockels Cell. Optical Engineering.33(8): 2746-2753, August 1994.

Munoz E, King TW, Frazier OH, Taegtmeyer H. Defective Glucose Metabolism in Uremic Hearts: A Possible mechanism for Contractile Dysfunction. Surgical Forum for the American College of Surgeons Clinical Congress.43: 290-291, October 11-16, 1992.

Patents

King TW, Patrick Jr. CW. Fabrication of biodegradable microspheres as carriers for bioactive proteins using a solid encapsulation/single emulsion/solvent extraction technique. Pending. Filed September 2000.

Book Chapters

King TW, Patrick Jr. CW. Ethical Considerations of Tissue Engineering on Society. In: Frontiers in Tissue Engineering, eds. Patrick Jr. CW, Mikos AG, McIntire LV. Elsevier Science, Oxford. January 1998.