In any 24-hour period, phlebotomy for research studies (all studies) in infants, children, and adults should not exceed 5% of the total blood volume and ideally should be less than 3% of the total blood volume.
In any one-month period, phlebotomy for research studies in infants, children, and adults should not exceed 10% of the total blood volume. The investigator must justify to CPHS the blood volume being requested from research participants.
AGE |
ESTIMATED TOTAL BLOOD VOLUME |
Pre-term newborn |
90 ml/kg |
Term newborn |
80 ml/kg |
1-12 months |
75 ml/kg |
1-3 years |
70 ml/kg |
4-12 years |
67.5 ml/kg |
Post-pubescent & Adults |
4000 ml – 5000 ml |
Please use the Pediatric Risk Assement Form for new protocols involving subjects less than 18 years of age. This form is avaible in the iRIS system.
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