I.06

 

Development, Approval and Maintenance of Policies and Procedures

 

 

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Objective

The University of Texas Health Science Center at Houston (UTHSC-H) Committee for the Protection of Human Subjects (CPHS) maintains written policies and procedures in compliance with federal regulations, State/local laws, UTHSC-H policies and procedures, and standards of regulatory, accrediting, and funding agencies that apply to research conducted under its jurisdiction.  This policy/procedure describes the processes for developing, approving, and maintaining them.

Policy/Procedure

I.              The UTHSC-H CPHS policies and procedures are developed and maintained by the Director of the Office of Research Support Committees (ORSC) under the direction of the CPHS Executive Committee Chairman.

 

II.           CPHS polices and procedures are to be reviewed every 2 years and when changes in regulations, laws, and institutional policies necessitate revision.

 

III.         The CPHS is charged with the implementation and enforcement of its policies and procedures.

 

IV.        It is the responsibility of the Principal Investigator (PI) to routinely view the CPHS website for new or revised CPHS policies and procedures.  In addition, new information can be disseminated via iRIS, during study coordinator meetings, and by regular updates to the electronic Investigator Handbook.

 

V.           Updates to the Investigator Handbook will be made every two years, alternating with the scheduled updates to the policies and procedures.

 

VI.        The Director of the Office of Research Support Committees (ORSC) will discuss with the CPHS Executive Committee and Office of Research Support Committees staff any necessary revisions of policies and procedures.

 

VII.      The CPHS and the Office of Legal Affairs and Institutional Compliance will maintain a joint relationship to discuss changes and assist with interpretation of Federal, State and local regulations affecting CPHS polices and procedures.

 

VIII.   The Director of the ORSC will provide educational sessions to the CPHS members and staff regarding CPHS policies and procedures, as well as updates or revisions in a timely manner.

 

IX.        The ORSC staff will use the CPHS policies and procedures when processing research activities and responding to PI queries.

 

X.           If the ORSC staff notices that a policy or procedure is inaccurate or out of date, the staff member should bring it to the attention of the Director of the ORSC who will verify the issue and bring it to the attention of the CPHS Executive Committee Chairman.  It is all ORSC staff’s responsibility to keep the CPHS policies and procedures current and applicable to the daily processes.

 

 

Applicable Regulations and Guidelines

21 CFR 50 ( http://www.access.gpo.gov/nara/cfr/waisidx_04/21cfr50_04.html )

21 CFR 50( http://www.access.gpo.gov/nara/cfr/waisidx_04/21cfr56_04.html )

38 CFR 16 ( http://www.access.gpo.gov/nara/cfr/waisidx_04/38cfr16_04.html )

45 CFR 46 ( http://www.access.gpo.gov/nara/cfr/waisidx_04/45cfr46_04.html )

ICH E6 ( http://www.ich.org/MediaServer.jser?@_ID=482&@_MODE=GLB )

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Updated 6/5/2007, Report broken links