Molecular Basis of Microbial Pathogenesis

MicPath Articles - January

The human microbiota - You have to know what's normal to know what's pathogenic!

(Dr. Norris)

Tuesday, Jan. 13

Assigned article

Palmer, C., E. M. Bik, D. B. DiGiulio, D. A. Relman, and P. O. Brown. 2007. Development of the human infant intestinal microbiota. PLoS Biology 5:e177. Link

Eukaryotic Pathogenesis

(Dr. Lorenz)

Thursday, Jan. 15 How to write a grant, plus

Assigned article

Verstrepen, et al. (2004) Intragenic tandem repeats generate functional variability. Nat. Genet. 37:986. Link

Introductory review

Verstrepen, et al. (2004) Origins of variation in the fungal cell surface. Nat. Rev. Micro. 2:533. Link

Tuesday, Jan. 20

Assigned article

Nobile, et al. (2008) Complementary adhesin function in C. albicans biofilm formation. Curr. Biol. 18:1017. Link

Introductory review

Dranganis, et al. (2007) A biochemical guide to yeast adhesins: glycoproteins for social and antisocial occasions. Microbiol. Mol. Biol. Rev. 71:282. Link

Thursday, Jan. 22

Assigned article

Phan, et al. (2007) Als3 is a Candida albicans invasin that binds to cadherins and induces endocytosis by host cells. PLoS Biol. 5:e64. Link

Introductory review

Filler (2006)Candida –host cell receptor–ligand interactions. Curr. Opin. Micro. 9:333. Link

Tuesday, Jan. 27

Assigned article

Almeida, et al. (2008) The hyphal-associated adhesin and invasin Als3 ofCandida albicans mediates iron acquisition from host ferritin. PLoS Pathog. 4:e1000217. Link

Thursday, Jan. 29

Assigned articles

Halme, et al. (2004) Genetic and epigenetic regulation of the FLO gene family generates cell-surface variation in yeast. Cell 116:405. Link

and

Domergue, et al. (2005) Nicotinic acid limitation regulates silencing ofCandida adhesins during UTI. Science 308:866. Link

If you have trouble with obtaining the .pdf file via the link, please contact Dr. Norris at Steven.J.Norris@uth.tmc.edu.)