Molecular Basis of Microbial Pathogenesis

MicPath Articles - March

Identifying Virulence Factors using a Model Host

(Dr. Garsin)

Tuesday, March 3, 2009.  Developing a Model Host System

Assigned Article:

Jha, A. K., H. P. Bais, and J. M. Vivanco. 2004. Enterococcus faecalis Mammalian Virulence-Related Factors Exhibit Potent Pathogenicity in the Arabidopsis thaliana Plant Model. Infection and Immunity 73:464-475.  Link

Useful Book Chapter (in MMG Library):

Gilmore, M. S., P. S. Coburn, S. R. Nallapareddy, and B. E. Murray. 2002. Enterococcal

Virulence in The Enterococci: Pathogenesis, Molecular Biology, and Antibiotic Resistance, M.S.

Gilmore, Editor. 2002, ASM Press: Washington, DC. p. 316-325.

 

Thursday, March 5, 2009.  Identifying Immune Responses Using Model Hosts I

Assigned Articles:

Styer, K. L., V. Singh, E. Macosko, S. E. Steele, C. I. Bargmann, A. Aballay. 2008. Innate Immunity is Regulated by Neurons Expressing NPR-1/GPCR. Science. 322:460-64.  Link

Reddy, K. C., E. C. Andersen, L. Kruglyak, D. H. Kim. 2009. A Polymorphism in npr-1 is a Behavioral Determinant of Pathogen Susceptibility in C. elegans. 323:382-84.  Link

 

Tuesday, March 17, 2009.  Identifying Immune Responses Using Model Hosts II

Assigned Article:

Ha, E. M., C. T. Oh, Y. S. Bae, W. J. Lee. 2005. A Direct Role for Dual Oxidase in Drosophilia Gut Immunity. Science. 310:847-850. Link

Groundwork Paper

Ha, E. M., C. T. Oh, J. H. Ryu, Y. S. Bae, S. W. Kang, I. H. Jang, P. T. Brey, W. J. Lee.  2005. Developmental Cell. 18:125-132.  Link

 

Bacterial Effector Protein Interactions 

(Drs. Xu and Hook)

Thursday, March 19, 2009. 

Assigned Review Article:

Mattoo, S., Y. M. Lee, and J. E. Dixon. 2007. Interactions of bacterial effector proteins with host proteins. Curr. Opin. Immunol. 19:392-401. Link

Tuesday, March 24, 2009. 

Assigned Article:

Alto, N. M., F. Shao, C. S. Lazar, R. L. Brost, G. Chua, S. Mattoo, S. A. McMahon, P. Ghosh, T. R. Hughes, C. Boone, and J. E. Dixon. 2006. Identification of a bacterial type III effector family with G protein mimicry functions. Cell 124:133-45. Link

Thursday, March 26, 2009. 

Assigned Article:

Chavakis, T., M. Hussain, S. M. Kanse, G. Peters, R. G. Bretzel, J. I. Flock, M. Herrmann, and K. T. Preissner. 2002. Staphylococcus aureus extracellular adherence protein serves as anti-inflammatory factor by inhibiting the recruitment of host leukocytes. Nat Med 8:687-93. Link

Tuesday, March 31, 2009. 

Assigned Article:

Machner, M. P., and R. R. Isberg. 2007. A bifunctional bacterial protein links GDI displacement to Rab1 activation. Science 318:974-7. Link

 

 

Under construction

If you have trouble with obtaining the .pdf file via the link, please contact Dr. Norris at Steven.J.Norris@uth.tmc.edu.)