ELECTRON MICROSCOPE REPORT TEMPLATES

Andy Nguyen, M.D. / UT-Medical School at Houston, Pathology/ Last Revision on: 7/6/2011

PLATELET EM

Microscopic:

The whole blood is centrifuged to obtain a platelet pellet for electron microscopy. Adequate numbers of platelets are available for evaluation. Ultra-structural photomicrographs show platelets with normal size. The platelets show adequate presence of both alpha and dense granules. A few of the platelets contain cytoplasmic glycogen, and several show pseudopod formation. The open canalicular system is normally formed. The contractile tubules, mitochondria also show normal morphology.

Diagnosis:

Platelets, electron microscopy:

- Normal platelet ultra-structure, see Comment.

- No evidence of platelet storage pool disease is seen.

CPT:88348 x1                       

Comment:

Review of patient’s laboratory results (MHH-EMR) shows normal platelet aggregation study, PT, PTT, and von Willebrand panel (samples collected on 10/8/2010)

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WBC EM:

Diagnosis:

Leukocytes, electron microscopy:

- Normal ultra structure.

- No evidence of cytoplasmic inclusions seen in MYH9-related disorders.

Comment:

Peripheral blood smear review (Memorial Hermann Laboratory, accession number xxxx, on xx/xx/2010) shows marked thrombocytopenia (plt 9k), small platelets, normal morphology of neutrophils with no evidence of Dohle-like bodies in cytoplasm.

EM
The whole blood sample is centrifuged to obtain a leukocyte pellet for electron microscopy. Adequate numbers of polymorphonuclear cells are available for evaluation. They show normal ultrastructure. No cytoplasmic patches typically associated with MYH9-related disorders are seen (patches consisting of small glycogen granules with fine electron-dense fibrils).

CPT 88348x1

+++++