ResearchClinical and basic research are major aspects of the Departments programs. Almost all faculty are engaged in research with the aim of discovering new knowledge and/or developing ways to apply new knowledge to improve diagnosis and management of disease. The research programs within the University, including Pathology and Laboratory Medicine, have grown dramatically in recent years as evidenced by funding levels and awards including the 1998 Nobel Prize in Medicine. The Department offers MS and Ph.D training through the GSBS (Graduate School of Biomedical Sciences at Houston). This school comprises both The University of Texas Medical School at Houston and the UT M.D. Anderson Cancer Center.
Centers / Facilities:
The FLUORESCENCE MICROSCOPY AND IMAGING CORE LABORATORY is a multi-user facility located in the Department of Pathology and Laboratory Medicine, on the second floor of The University of Texas Medical School at Houston. The microscopy suite itself can be found in the white section (Room 2.221L: 713-500-5260).
The purpose of this facility is to allow research scientists access to state of the art fluorescence microscopy and imaging equipment, thereby furthering understanding in many diverse areas of clinical and basic research. We welcome local, national and international researchers with the hope that they will use these facilities fostering symbiotic and collaborative undertakings.
CIRC participants are engaged in research and development in the following fields: study of immunological defense by naturally occurring catalytic antibodies in infection by Human Immunodeficiency Virus-1, Hepatitis Virus C and Staphylococcal aureus; development of catalytic monoclonal antibodies and electrophilic vaccines to these pathogens; antigen-specific B cell tolerance induction in hemophilia; study of the role of catalytic antibodies to amyloid beta peptide in Alzheimer’s Disease and development of monoclonal antibodies for immune therapy against cognitive dysfunction; development of electrophilic analogs of alloantigens and autoantigens for inducing therapeutic B and T cell tolerance; study of crystal structures of chemically reactive antibodies; and, study of the reaction pathways employed by catalytic and irreversibly binding antibodies using enzymology and immunochemical methods.
- Brought to you by the Treponema pallidum Molecular Genetics Group Coordinated by Steve Norris at The University of Texas Medical School at Houston.
- Summer research projects for undergraduates and Ph.D. fellowships in Infectious Disease Research are available within the world-famous Texas Medical Center in Houston, Texas. Our goal is to provide training in the latest technologies that will lead to a career in one of the most exciting and dynamic areas in science today.
- Our laboratory uses high resolution electron cryomicroscopy to explore the biology of alphavirus replication including assembly and the host-virus interactions that are necessary for infection.