Wan, David Q., M.D.

FILED AS:

Faculty, Nuclear Medicine

UPDATED ON:

January 11th, 2011

TAGGED:

Assistant Professor

Professional Focus:

I am an American Board of Nuclear Medicine certified physician. My special interest is in the clinical application of PET in cancer diagnosis and neurological applications, such as Alzheimer’s disease.

My research interest is diagnosis and treatment of thyroid disease, including hyperthyroidism, thyroid cancer with metastases.

Graduate/Medical Degrees:

MD China Medical University, China

Postgraduate Training:

Residency: Memorial Sloan Kettering Cancer Center, New York, NY
Fellowship: University of Washington, Seattle, WA

Board Certifications:

American Board of Nuclear Medicine
Certification Board of Nuclear Cardiology

Publications:

18F-Fluorodeoxy glucose (FDG) uptake in nontraumatic bilateral adrenal hemorrhage secondary to heparin-associated thrombocytopenia syndrome (HATS)—a case report. Usha A. Joseph, Bruce J. Barron, and David Q. Wan. Clinical Imaging, Volume 31, Issue 2, March-April 2007, Pages 137-140. Full Text and Links

Y. M. Kong, D. J. McCormick, Q. Wan, R. W. Motte, A. A. Giraldo, B. E. Fuller, and C. S. David: Primary hormonogenic sites as conserved autoepitopes in murine autoimmune thyroiditis: Second role of iodination. The Journal of Immunology, 1995, 155: 5847-5854.

M. Nakashima, Y. M. Kong, Q. Wan, T. F. Davies: Prospective study of T cell receptor utilization following the induction of murine thyroiditis. Experimental and Clinical Endocrinology & Diabetes, 1996, 104, suppl. 4: 46-51.

Q. Wan, R. W. Motte, B. E. Fuller, A. A. Giraldo, D. J. McCormick, C. S. David and Y. M. Kong: Primary hormonogenic sites as conserved autoepitopes in murine autoimmune thyroiditis: Role of MHC Class II. Clinical Immunology and Immunopathology. 85(2), 187-194, 1997.

Q. Wan, D. J. McCormick, C. S. David and Y. M. Kong: Thyroglobulin peptides of specific primary hormonogenic sites can generate cytotoxic T cells and serve as target autoantigens in experimental autoimmune thyroiditis. Clinical Immunology and Immunopathology. 86(1), 110-114, 1998. 50, 22-30, 1999.

Q. Wan, R. Shah, D. J. McCormick, L. C. Lomo, A. A. Giraldo, C. S. David and Y. M. Kong: H2E transgenic class II-negative mice can distinguish self from non-self in susceptibility to heterologous thyroglobulins in autoimmune thyroiditis. Immunogenetics.

Y. Yan, J. Panos, D. J. McCormick, Q. Wan, A. A. Giraldo, V. Brusic, C. S. David and Y. M. Kong: Characterization of a navel H2A -E+ transgenic model susceptible to heterologous but not self thyroglobulin in autoimmune thyroiditis: Thyroiditis transfer with Vß8+ T cells. Cellular Immunology, 212, 63-70, 2001.

Q. Wan, M. Kita, J.C. Flynn, J.C. Panos, R.W. Motte, T. F. Davies, A.A. Giraldo, C.S. David and Y.M. Kong: Participation of Vß 13 and Vß 1 T cells in transfer thyroiditis after activation of mouse thyroglobulin-primed T cells by Superantigen staphylococcal enterotoxin A. Cellular Immunology, 213, 149-157, 2001.

Q. Wan, R. Shah, J.C. Panos, A. A. Giraldo, C. S. David and Y. M. Kong, HLA-DR and HLA-DQ polymorphism in human thyroglobulin-induced autoimmune thyroiditis: DR3 and DQ8 transgenic mice are susceptible. Human Immunology, 63, 301-310, 2002.

J. C. Flynn, Q. Wan, J. Panos, D. J. McCormick, A. A. Giraldo, C. S. David and Y. M. Kong, Coexpression of susceptible and resistant HLA class II transgenes in murine experimental autoimmune thyroiditis: DQ8 molecules down regulate DR3-mediated thyroiditis. J Autoimmunity, 18(3): 213-20. 2002.

Y. M. Kong, J. C. Flynn, Q. Wan, and C. S. David: HLA and H2 Class II transgenic mouse models to study susceptibility and protection in autoimmune thyroiditis: J. Autoimmunity, 36 (6-7): 397-404. 2003.

J.C. Flynn, A. Gardas, Q. Wan, M. Gora, G. Alsharabi, W.Z. Wei, A. A. Giraldo, C.S. David, Y.M. Kong and J.P. Banga: Superiority of thyroid peroxidase DNA over protein immunization in replicating human thyroid autoimmunity in HLA-DRB1*0301 (DR3) transgenic mice. Clinical and Experimental Immunology, 137 (3): 503-512 Sep 2004.

J.C. Flynn, D.J. McCormick, V. Brusic, Q. Wan, J. Panos,A.A. Giraldo, C. S. David and Y.M. Kong: Pathogenic human thyroglobulin peptides in HLA-DR 3 transgenic mouse model of autoimmune thyroiditis”. Cellular Immunology, 229(2): 79-85. June 2004.

R. J. Robbins, Q. Wan, R. K. Grewal, R. Reibke, M. Gonen, H. W. Strauss, R. M. Tuttle, W. Drucker, S.M. Larson: Real-time Prognosis for Metastatic Thyroid Carcinoma Based on FDG-PET Scanning. J Clin Endocrinol Metab. 2005-epub ahead of print. Nov 22, 2005.

Presentations:

Barron B, Joseph U, Wan D.: Mysterious Radiopharmaceutical Localization: A Pictorial Interactive Exhibit. Accepted for computerized electronic presentation at the ARRS 2007 annual meeting, Orlando, FL, May 6-11, 2007.