The University of Texas Medical School at Houston department of Diagnostic and Interventional Imaging
Department of Diagnostic and Interventional Imaging
The Department of Diagnostic and Interventional Imaging

Faculty Biography






Khader M. Hasan, Ph.D.



Faculty List

Professional Focus:

My research at UT has culminated in the establishment of the Diffusion Tensor Imaging Lab (MSB 6.532, (713-500-7683) which currently provides help to more than 10 different research active groups. The DTI lab is part of the MRI research wing of the department and its major role is promote and support the department MRI main research. The DTI lab provides computational support, training, processing and consultation on data acquisition, management, detailed and professional quality control measures for researchers, clinical center trials and complete processing of data acquired from many scanners, at different scales that span the mouse, rat and the human CNS. My main research focuses on developing specialized acquisition and computational techniques to enhance contrast and increase specificity of DTI. The fusion of DTI and MEG, fMRI, perfusion, conventional MRI and MRSI will be important to identify noninvasive markers for quantifying and localizing human neurodegenerative diseases such as multiple sclerosis (collaborative work with Drs Jerry Wolinsky, Ponnada A. Narayana and Flavia Nelson), neurodevelopmental disorders such as Spina Bifida and Dyslexia (collaborative work with Drs Jack Fletcher, Maureen Dennis, Andrew Papanicolaou, Larry Kramer, Susan Blaser), pediatric traumatic brain injury (collaborative work with Dr Linda Ewing-Cobbs), neurotoxins such as cocaine and MDM (collaborative work with Drs Gerry Moeller and Joel L Steinberg). Many other applications of DTI such as fetal brain maturation and development and clinical applications (stroke, tumors, epilepsy, Hypoxic injury) are also ongoing (collaborative work with Dr Rakesh K Gupta, Andrew Papanicolaou, Corwin Boake), modeling of spinal cord injury recovery and therapy (collaborative work with Dr Ponnada A. Narayana) and modeling of animal disease such as Parkinson's, ALS, HIV (collaborative work with Drs Michael Boska and Howard Gillerman). Other collaborative DTI applications to human CNS conditions such as Schizophrenia, ADHD and Autism are also underway (Manzar Ashtari, Joel L Steinberg, Mike Brandt).

Summer students, graduate and postdoctoral fellows are encouraged to visit and apply to the DTI lab to learn and contribute.

Major Honors or Awards:

1998 Trainer of New Physics Graduate Teaching Assistants
1996 Outstanding Teaching Assistant in Physics
1995 Outstanding Teaching Assistant in Physics
1994 Outstanding Teaching Assistant in Physics
1992 Outstanding Teaching Assistant in Physics

Book Chapters:

Printer-friendly version of Publications and Presentations

1. Hasan KM. Fundamentals of Diffusion Tensor Imaging of the Entire Human Brain: Review of Basic Theory, Data Acquisition, Processing and Potential Applications at 1.5 T and 3.0 T. Chapter 1. p 1-80. In Chen FJ. Progress in Brain Mapping Research. Nova Science Publishers, Hauppauge NY, 2006 https://www.novapublishers.com/catalog/product_info.php?products_id=3764

2. Hahn KR, Prigarin S, Heim S, Hasan KM. Random noise in Diffusion Tensor Imaging, its Destructive Impact and Some Corrections. In: J. Weickert and H. Hagen, editors. Visualization and Processing of Tensor Fields. Berlin: Springer; 2005.

3. Ewing-Cobbs, L., Prasad, M., & Hasan, K.M. Developmental plasticity and reorganization of function following early brain injury. In Nelson CA and Luciana M (Eds). Handbook of Developmental Cognitive Neuroscience (2nd Ed), MIT Press, Cambridge, Mass. In press.

Publications:

1. Hasan KM, Narayana PA. Magnetic Resonance Imaging–Based Quantitative Iron Mapping at 7-Tesla Remains to Be Elusive in Multiple Sclerosis. Annals of Neurology 2009 (DOI: 10.1002/ana.21665).

2. Hasan KM, Pedraza O. Improving the Reliability of Manual and Automated Methods for Hippocampal and Amygdala Volume Measurements. Neuroimage 2009 (in press; doi:10.1016/j.neuroimage.2009.05.004).

3. Hasan KM, Iftikhar A, Kamali A, Kramer A, Ashtari M, Cirino PT, Papanicolaou AC, Fletcher JM, Ewing-Cobbs L. Development and Aging of the Healthy Human Brain Uncinate Fasciculus across the Lifespan using Diffusion Tensor Tractography. Brain Research 2009 (in press; doi:10.1016/j.brainres.2009.04.025).

4. Dennis M, Hopyan T, Juranek J, Cirino PT, Hasan KM, Fletcher JM. Strong-meter and weak-meter rhythm identification in spina bifida meningomyelocele and volumetric parcellation of rhythm-relevant cerebellum regions. Annals of the New York Academy of Sciences 2009 (in press).

5. Ma L, Hasan KM, Steinberg JL, Narayana PA, Lane SD, Zuniga EA, Kramer LA, Moeller FG. Diffusion Tensor Imaging in Cocaine Dependence: Regional Effects of Cocaine on Corpus Callosum and Effect of Cocaine Administration Route. Drug and Alcohol Dependence 2009 (in press).

6. Hahn KR, Prigarin S, Rodenacker K, Hasan KM. Denoising for Diffusion Tensor Imaging with low Signal to Noise Ratios: Method and Monte Carlo Validation. International Journal for Biostatistics and Biomathematics 2009 (in press).

7. Kumar R, Husain M, Gupta RK, Hasan KM, Haris M, Agarwal AK, Pandey CM, Narayana PA. Serial Changes in the White Matter Diffusion Tensor Imaging Metrics in Moderate Traumatic Brain Injury and Correlation with Neuro-Cognitive Function. Journal of Neurotrauma 2009; 26:1–16.

8. Kamali A, Kramer LA, Butler IJ, Hasan KM. Diffusion Tensor Tractography of the Somatosensory System in the Human Brainstem: Initial findings using high isotropic spatial resolution at 3.0 T. Eur Radiol. 2009;19(6):1480-1488

9. Hasan KM. A questionable gold standard for hippocampal volumetry and asymmetry. Neuroradiology 2009; 51:201-202.

10. Hasan KM, Kamali A, Kramer L. Mapping the human brain white matter tracts relative to cortical and deep gray matter using diffusion tensor imaging at high spatial resolution. Magn Reson Imaging 2009; 27(5): 631-636.

11. Hasan KM, Halphen C, Kamali A, Nelson F, Wolinsky JS, Narayana PA. Caudate Nuclei Volume, Diffusion Tensor Metrics, and T2 Relaxation in Healthy Adults and Relapsing- Remitting Multiple Sclerosis Patients: Implications for Understanding Gray Matter Degeneration. Journal of Magnetic Resonance Imaging 2009; 29(1):70-77.

12. Hasan KM, Kamali A, Iftikhar A, Kramer LA, Papanicolaou AC, Fletcher JM, Ewing-Cobbs L. Diffusion Tensor Tractography Quantification of the Human Corpus Callosum Fiber Pathways across the Lifespan. Brain Research 2009; 1245;91-100

13. Castillo EM, Fletcher JM, Zhimin L, Mayre H, Hasan KM, Passaro A, Papanicolaou AC. Transcallosal connectivity and cortical rhythms in Spina Bifida and Hydrocephalus. Neuroreport 2009 (in press).

14. Hasan KM, Kamali A, Kramer LA, Papanicolaou AC, Fletcher JM, Ewing-Cobbs L. Diffusion Tensor Quantification of the Human Midsagittal Corpus Callosum Subdivisions across the Lifespan. Brain Research 2008;1227:52-67.

15. Hasan KM, Ewing-Cobbs L, Kramer LA, Fletcher JM, and Ponnada A. Narayana. Diffusion tensor quantification of the macrostructure and microstructure of human midsagittal corpus callosum across the lifespan. NMR Biomed. NMR Biomed. 2008; 21(10):1094-1101.

16. Hasan KM, Sankar A, Halphen C, Kramer LA, Ewing-Cobbs L, Dennis M, Fletcher JM. Quantitative Diffusion Tensor Imaging and Intellectual Outcomes in Spina Bifida. Journal of Neurosurgery Pediatrics 2008; 2(1):75-82.

17. Hasan KM. Experimental validation, quality control methods and unified theory for DTI error propagation are needed: a rebuttal, Magnetic Resonance Imaging 2008; 26(8):1199-1200 (Letter to the Editor).

18. Frye RE, Hasan K, Xue L, Strickland D, Malmberg B, Liederman J, Papanicolaou A. Splenium microstructure is related to two dimensions of reading skill. Neuroreport. 2008;19(16):1627-1631.

19. Hasan KM, Eluvathingal TJ, Kramer LA, Ewing-Cobbs L, Dennis M, Fletcher JM. White Matter Microstructural Abnormalities in Children with Spina Bifida Myelomeningocele and Hydrocephalus: A Diffusion Tensor Tractography Study of the Association Pathways. Journal of Magnetic Resonance Imaging 2008;27:700–709.

20. Hasan KM, Halphen C, Boska MD, Narayana PA. Diffusion Tensor Metrics, T2 Relaxation and Volumetry of the Naturally Aging Human Caudate Nuclei in Healthy Young and Middle-Aged Adults: Possible Implications to the Neurobiology of Human Brain Aging and Disease. Magn Reson Med 2008; 59(1):7-13.

21. Hasan KM. A Framework for Quality Control and Parameter Optimization in Diffusion Tensor Imaging: Theoretical Analysis and Validation. Magnetic Resonance Imaging 2007; 25(8):1196-1202.

22. Hasan KM, Sankar A, Halphen C, Kramer LA, Brandt ME, Juranek J, Cirino PT, Fletcher JM, Papanicolaou AC, Ewing-Cobbs L. Development and Organization of Human Brain Tissue Compartments across Lifespan using Diffusion Tensor Imaging. Neuroreport 2007;18(16):1735-1739.

23. Hasan KM, Halphen C, Sankar A, Eluvathingal TJ, Kramer L, Stuebing KK, Ewing-Cobbs L, Fletcher JM. Diffusion Tensor Imaging Based Tissue Segmentation: Validation and Application to the Developing Child and Adolescent Brain. Neuroimage 2007;34(4):1497-1505.

24. Ewing-Cobbs L, Prasad M, Swank P, Kramer L, Cox C, Fletcher JM, Barnes M, Zhang X, Hasan KM. Arrested Development and Disruption of Myelin in the Corpus Callosum following Pediatric Traumatic Brain Injury. Neuroimage 2008; 42:1305-1315.

25. Poonawalla AH, Hasan KM, Gupta RK, Ahn C, Nelson F, Wolinksy JS, Narayana PA. Diffusion Tensor Imaging of Cortical Lesions in Multiple Sclerosis - Initial Findings. Radiology 2008; 246(3):880-886.

26. Juranek J, Fletcher JM, Hasan KM, Breier JI, Cirino PT, Pazo-Alvarez P, Diaz JJ, Ewing-Cobbs L, Dennis M, Papanicolaou AC. Neocortical reorganization in spina bifida. NeuroImage 2008;40:1516–1522

27. Breier JI, Hasan KM, Zhang W, Men D, Papanicolaou AC. Language dysfunction after stroke and damage to white matter tracts using diffusion tensor imaging. AJNR Am J Neuroradiol. 2008;29(3):483-487.

28. Eluvathingal TJ, Hasan KM, Kramer L, Fletcher JM, Ewing-Cobbs L. Quantitative Diffusion Tensor Tractography of Association and Projection Fibers in Normally Developing Children and Adolescents. Cereb Cortex. 2007;17(12):2760-2768. (http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2084482)

29. Papanicolaou AC, Hasan KM, Boake C, Eluvathingal TJ, Kramer L. Disruption of limbic pathways in a case of profound amnesia.Neurocase. 2007;13(4):226-826.

30. Boska MD, Hasan KM, Kibuule D, Banerjee R, McIntyre E, Nelson JA, Hahn T, Gendelman HE, Mosley RL. Quantitative diffusion tensor imaging detects dopaminergic neuronal degeneration in a murine model of Parkinson's disease. Neurobiol Dis. 2007;26(3):590-596.

31. Breier JI, Maher LM, Schmadeke S, Hasan KM, Papanicolaou AC. Changes in Language-specific Brain Activation after Therapy for Aphasia using Magnetoencephalography: A Case Study. Neurocase. 2007;13(3):169-177.

32. Moeller FG, Steinberg JL, Lane SD, Buzby M, Swann AC, Hasan KM, Kramer LA, Narayana PA. Diffusion Tensor Imaging in MDMA Users and Controls: Association with Decision Making. Am J Drug Alcohol Abuse. 2007;33(6):777-789.

33. Moeller FG, Hasan KM, Steinberg JL, Kramer LA, Valdes I, Lai LY, Swann AC, Narayana PA. Diffusion tensor imaging eigenvalues: Preliminary evidence for altered myelin in cocaine dependence. Psychiatry Research: Neuroimaging 2007;154(3):253-258.

34. Ashtari M, Cervellione KL, Hasan KM, Wu J, McIlree C, Kester H, Babak A. Ardekani BA, Roofeh D, Szeszko PR, Kumra S. White Matter Development during Late Adolescence in Healthy Males: A Cross-Sectional Diffusion Tensor Imaging Study Neuroimage 2007; 35:501-510.

35. Eluvathingal TJ, Hasan KM, Kramer L, Fletcher JM, Ewing-Cobbs L. Quantitative Diffusion Tensor Tractography of Association and Projection Fibers in Normally Developing Children and Adolescents. Cereb Cortex. 2007;17(12):2760-2768. (http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2084482)

36. Mosley RL, Benner EJ, Kadiu I, Thomas M, Boska MD, Hasan KM, Laurie C, Gendelman HE. Neuroinflammation, oxidative stress, and the pathogenesis of Parkinson’s disease. Clinical Neuroscience Research 2006; 6:261–281.

37. Malik GK, Trivedi R, Gupta RK, Hasan KM, Hasan M, Gupta A, Pandey CM, Narayana PA. Related Articles. Serial Quantitative Diffusion Tensor MRI of the Term Neonates with Hypoxic-Ischemic Encephalopathy (HIE). Neuropediatrics. 2006;37(6):337-343.

38. Haris M, Gupta RK, Husain N, Hasan KM, Husain M, Narayana PA. Measurement of DTI metrics in hemorrhagic brain lesions: possible implication in MRI interpretation. J Magn Reson Imaging. 2006;24(6):1259-1268.

39. Hasan KM., Narayana PA. Retrospective Measurement of the Diffusion Tensor Eigenvalues from Diffusion Anisotropy and Mean Diffusivity in DTI. Magnetic Resonance in Medicine, 2006:56:(1):130-137.

40. Hasan KM. Diffusion tensor eigenvalues or both mean diffusivity and fractional anisotropy are required in quantitative clinical diffusion tensor MR reports: fractional anisotropy alone is not sufficient. Radiology. 2006;239(2):611-612.

41. Deo AA, Grill R.J., Hasan KM, Narayana P.A. In Vivo Longitudinal Diffusion Tensor Imaging of Experimental Spinal Cord Injury. J Neurosci Res. 2006;83(5):801-810.

42. Ewing-Cobbs L, Hasan KM, Prasad MR, Kramer L, Bachevalier J. Corpus callosum diffusion anisotropy correlates with neuropsychological outcomes in twins disconcordant for traumatic brain injury. AJNR Am J Neuroradiol. 2006;27(4):879-881.

43. Trivedi R, Gupta R.K., Agarawal A, Hasan KM, Getaneh Bayu, Divya Rathore, Ram Kishore S Rathore, Narayana PA. Assessment of white matter damage in subacute sclerosing panencephalitis using quantitative diffusion tensor MRI. AJNR, 2006;27(8):1712-1716.

44. Gupta R.K., Saksena S., Hasan KM., Agarwal A., Haris M, Chandra M., Pandey CM, Narayana PA. Focal Wallerian Degeneration of Corpus Callosum in Large Middle Cerebral Artery Stroke: Serial Diffusion Tensor Imaging. Journal of Magnetic Resonance Imaging 2006; 24(3):549-555.

45. Trivedi R, Gupta RK, Hasan KM, Hou P, Prasad KN, Narayana PA. Related Articles, Links Diffusion tensor imaging in polymicrogyria: a report of three cases. Neuroradiology 2006;48(6):422-427.

46. Kale RA, Gupta RK, Saraswat VA, Hasan KM, Trivedi R, Mishra AM, Ranjan P, Pandey CM, Narayana PA. Demonstration of interstitial cerebral edema with diffusion tensor MR imaging in type C hepatic encephalopathy. Hepatology. 2006;43(4):698-706. Abstract, References, HTML, PDF.

47. Gupta RK, Saksena S, Agarwal A, Hasan KM, Husain M, Gupta V, Narayana, PA. Diffusion Tensor Imaging in Late Posttraumatic Epilepsy. Epilepsia 46(9):1465-1471. Available at: http://www.blackwell-synergy.com/doi/abs/10.1111/j.1528-1167.2005.01205.x?journalCode=epi&volume=46&issue=9&cookieSet=1

48. Hasan KM, Rakesh K. Gupta, Santos RM, Wolinsky JS, Narayana PA. Fractional Diffusion Tensor Anisotropy of the seven segments of the Normal-Appearing White Matter of the Corpus Callosum in Healthy Adults and Relapsing Remitting Multiple Sclerosis. Journal of Magnetic Resonance Imaging, 2005;21(6):735-743. PDF, Abstract.

49. Hasan KM, Narayana PA. DTI parameter optimization at 3.0 T: potential application in entire normal human brain mapping and multiple sclerosis research. MedicaMundi 2005; 49(1):30-45 - which is also available @ http://www.medical.philips.com/main/news/assets/docs/medicamundi/mm_vol49_no1/07_Hasan.pdf

50. Gupta RK, Hasan KM, Mishra AM, Jha D, Husain M, Prasad KN, Narayana PA. High Fractional Anisotropy in Brain Abscesses versus Other Cystic Intracranial Lesions. AJNR Am J Neuroradiol. 2005; 26(5):1107-1114. PDF, Abstract.

51. Gupta RK, Hasan KM, Trivedi R, Pradhan M, Das V, Parikh NA, Narayana PA. Diffusion tensor imaging of the developing human cerebrum. J Neurosci Res. 2005 Jul 15;81(2):172-8.

52. Madi S, Hasan KM, Narayana PA. Diffusion tensor imaging of in vivo and excised rat spinal cord at 7 T with an icosahedral encoding scheme. Magn Reson Med 53(1):118-125, 2005.

53. Moeller FG, Hasan KM, Joel L. Steinberg JL, Kramer L, Dougherty DM, Santos RM Valdez , Swann AC, Barratt ES, Ponnada A. Narayana. Reduced Anterior Corpus Callosum White Matter Integrity as Measured by Diffusion Tensor Imaging is Related to Impulsivity in Cocaine-Dependent Subjects. Neuropsychopharmacology 30(3):610-617, 2005.

54. Hou P, Hasan KM, Sitton CW, Wolinsky JS, Narayana PA, Phase Sensitive T1 Inversion Recovery Imaging: A Time Efficient Interleaved Technique for Improved Tissue Contrast in Neuroimaging. AJNR Am J Neuroradiol. 2005; 26(6):1432-1438.

55. Field AS, Alexander AL, Wu YC, Hasan KM, Witwer B, Badie B. Diffusion tensor eigenvector directional color imaging patterns in the evaluation of cerebral white matter tracts altered by tumor. J Magn Reson Imaging 20(4):555-562, 2004.

56. Hasan KM, Narayana PA. Does Fractional Anisotropy Have Better Noise Immunity Characteristics than the Relative Anisotropy in Diffusion Tensor MRI: An Analytical Approach? Magn Reson Med 2004; 51:413-417. PDF, Abstract, Full Text.

57. Field S, Hasan K, Jellison BJ, Arfanakis K, Alexander ALA. Diffusion Tensor Imaging in an Infant with Traumatic Brain Swelling. AJNR Am J Neuroradiology 24(7):1461-1464; 2003. PDF, Full Text, Abstract.

58. Hasan KM and Narayana PA. Computation of the Mean Diffusivity, and Fractional Anisotropy Maps Without Tensor Decoding and Diagonalization: Theoretical Analysis and Experimental Validation. Magnetic Resonance in Medicine, 50: 589-598; 2003. PDF version, HTML.

59. Lazar M, Weinstein DM, Tsuruda JS, Hasan KM, Arfanakis K, Meyerand ME, Badie B, Rowley HA, Haughton V, Field A, Alexander AL. White matter tractography using diffusion tensor deflection. Hum Brain Mapp. 2003 Apr; 18(4):306-21.

60. Witwer BP, Moftakhar R, Hasan KM, Deshmukh P, Haughton V, Field A, Arfanakis K, Noyes J, Moritz CH, Meyerand ME, Rowley HA, Alexander AL, Badie B. Diffusion-tensor imaging of white matter tracts in patients with cerebral neoplasm. J. Neurosurg. 97(3):568-575 (2002).

61. Hasan KM, Parker DL, Alexander AL. Magnetic resonance water self-diffusion tensor encoding optimization methods for full brain acquisition. Image Analysis and Stereology 21(2):87-96 (2002). (Invited paper) (Missing_IAS_figures_7_10).

62. Hasan KM, Parker DL, Alexander AL. Comparison of Optimization Procedures for Diffusion-Tensor Encoding Directions. JMRI 13:769-780 (2001).

63. Hasan KM, Basser PJ, Parker DL, Alexander AL. Analytical Computation of the Eigenvalues and Eigenvectors in DT-MRI. JMR 152(1): 41-47 (2001).

64. Alexander AL, Hasan KM, Kindlmann G, Parker DL, Tsuruda J. A Geometric Analysis of Diffusion Tensor Measurements of the Human Brain. Magnetic Resonance in Medicine 44: 283-291 (2000).

65. Alexander AL, Hasan KM, Lazar M, Tsuruda J, Parker DL. Analysis of Partial Volume Effects in Diffusion-Tensor MRI. Magn. Reson. Med. 45:770-780 (2001).

66. Sato T, Hasan KM, Alexander AL, Minato K. Structural connectivity in white matter using the projected diffusion-tensor distance. Medinfo 10(2):929-932 (2001).

Abstracts and Presentations:

 1. Hasan KM, Kamali A, Juranek J. Mapping the Human Brain Fiber Tracts Relative to Deep and Cortical Gray Matter Using Diffusion Tensor Imaging at High Angular and Spatial Resolution. The Houston Society for Engineering in Medicine and Biology (HSEMB 08 Conference), Houston, 02/07/2008 (Invited Talk).

 2. Hasan KM, Halphen C, Kamali A, Wolinsky JS, Narayana PA. Caudate Nuclei Degeneration in Multiple Sclerosis: A Multi-Modal Quantitative MRI Approach. Proceedings of the 16th ISMRM Meeting and Exhibition. Toronto, Canada. May 3-9, 2008: p1615.

 3. Hasan KM, Halphen C, Kamali A, Wolinsky JS, Narayana PA. A Diffusion Tensor Imaging Surrogate Marker of Brain Atrophy in Multiple Sclerosis. Proceedings of the 16th ISMRM Meeting and Exibition, Toronto, Canda May 3-9, 2008: p 708.

 4. Kamali A, Juranek J, Hasan KM. Mapping the Human brain fiber pathways using diffusion tensor imaging at high angular and spatial resolution. Neuroscience Research Center 14th Annual Poster Session, 12/1/2007, #32.

 5. Hasan KM, Kamali A, Iftikhar A, Kramer LA, Papanicolaou AC, Fletcher JM, Ewing-Cobbs L. Diffusion Tensor Tractography Quantification of the Human Corpus Callosum Fiber Pathways across the Lifespan. Brain Research 2009; 1245;91-100 (doi:http://dx.doi.org/10.1016/j.brainres.2008.10.026).

 6. Dennis M, Hopyan-Misakyan T, Juranek, J., Cirino, P, Hasan KM, Fletcher, J. Strong and Weak Metric Rhythm Identification in Spina Bifida Meningomyelocele in Relation to Parcellated Anterior and Posterior Cerebellar Volumes. Neuroscience & Music III: Disorders & Plasticity. June 25-28, 2008, Montreal, Canada.

 7. Moeller FG, Lewis CP, Hasan KM, Kramer, L.A., Narayana PA, Swann AC. Diffusion Tensor Imaging Measured Whole Brain White Matter Integrity and Impulsivity in Cocaine Dependence. American College of Neuropsychopharmacology Annual Meeting, Boca Ratton, Florida December, 2007.

 8. Halphen C, Hasan KM, Narayana PA. Diffusion Tensor Imaging, T2 Relaxation and Volumetry of the Aging Human Caudate. Presented at the 10th University of Texas Neuroscience Research Conference (Dec 10 2006).

 9. Hasan KM and others # 2713. A Multi-Scale Whole-Brain Optimized Diffusion Tensor Imaging of Dyslexics at 3.0T ISMRM 2007, Berlin Germany

10. Boska M, Hasan KM and others #5031. Quantitative Diffusion Tensor Imaging in a murine model of Parkinson’s Disease ISMRM 2007, Berlin Germany

11. Kramer LA, Hasan KM and colleagues #78. Comparison of Left and Right Ventricle Functional Measurements Using Steady State Free Precession-Short Axis versus Four Chamber Analysis ISMRM 2007, Berlin Germany.

12. Poonawalla AH, Hasan KM, and others #4898. Increased Fractional Anisotropy in cortical lesions in multiple sclerosis. ISMRM 2007, Berlin Germany.

13. Hahn K, Hasan KM and coleagues. Can we expect reproducible and unbiased information from denoised Diffusion Tensor Imaging with low SNR. #2797

14. Hasan KM. Diffusion Tensor Imaging of the Corpus Callosum in Multiple Sclerosis and Healthy Adults. University of Texas Houston, U of T, Research Retreat, the Houstonian March 04, 2005 (talk).

15. Hasan KM. Diffusion Tensor Imaging of Wallerian Degeneration: Application to Multiple Sclerosis. University of British Coloumbia, Vancouver, Canada Dec 1st, 2004 (Invited Talk).

16. Hasan KM. Diffusion Tensor Imaging of Wallerian Degeneration: Application to Multiple Sclerosis. University of Texas Houston, Grand Rounds in Neurology Feb 04, 2005 (Invited Talk).

17. Hasan KM. Applications of Diffusion Tensor Imaging to Human Brain Mapping. University of Nebraska Medical Schhool, Omaha, Jul 14, 2005 (Invited Talk).

18. Hasan KM. Department of Diagnostic Imaging wide Research Seminar. Diffusion Tensor Imaging of the Human Brain, June 2006.

19. Hasan KM, Rodenacker K and Hahn KR. Evaluation of SNR Performance and Utility of High Spatial and Angular Resolution Denoised 1mm3 Isotropic DTI of Entire Human Brain at 3.0 T International Society of Magnetic Resonance in Medicine 14 th Meeting in Seatle, Washington, USA, May 6-12, 2006 (talk)

20. Hasan KM,Sankar A, Kramer L, Linda Ewing-Cobbs L, Brandt M, Hannay J, Blaser S, Dennis M, Fletcher JM. Diffusion Tensor Imaging of the Spina Bifida Menigomyelocele at 3.0T: Preliminary evidence of Neurodevelopmental Brain plasticity . International Society of Magnetic Resonance in Medicine 14 th Meeting in Seatle, Washington, USA, May 6-12, 2006 (talk)

21. Hasan KM, Sankar A, Kramer L, Prasad M, Ewing-Cobbs L. Arcuate Fasciculus Maturation is Impaired in Pediatric Traumatic Brain Injury: A DTI Study at 3.0 T. International Society of Magnetic Resonance in Medicine 14 th Meeting in Seattle, Washington, USA, May 6-12, 2006 (talk)

22. Hasan KM, Ahn C, Gupta RK, Kramer L, Ewing-Cobbs L, Fletcher Jack, Narayana PA Diffusion Tensor Longitudinal Diffusivity Differences In the Body of the corpus callosum of Age-Matched Male and Female Adults. International Society of Magnetic Resonance in Medicine 14 th Meeting in Seatle, Washington, USA, May 6-12, 2006 (talk)

23. Deo AA, Grill RJ, Hasan KM, Narayana PA. In vivo Longitudinal Diffusion Tensor Imaging of Spinal Cord Injury in Rats International Society of Magnetic Resonance in Medicine 14 th Meeting in Seatle, Washington, USA, May 6-12, 2006 (talk given on behalf of Deo)

24. Deo AA, Grill R, Hasan KM, Narayana PA. In vivo Regional Diffustion Tensor Metrics of Rodent Spinal Cord. International Society of Magnetic Resonance in Medicine 14 th Meeting in Seattle, Washington, USA, May 6-12, 2006.

25. Kramer LA, Hasan KM, Sankar A, Prasad MR, Bachevalier J, Fletcher JM, Ewing-Cobbs L Anisotropy and Diffusivity in Corpus Callosal Subregions after Pediatric TBI International Society of Magnetic Resonance in Medicine 14 th Meeting in Seatle,Washington, USA, May 6-12, 2006.

26. Kishore V. Mogatadakala KV, Datta S, Poonavalla A, Hasan KM, Wolinsky JS, Narayana PA Identification of Abnormal White Matter in Multiple Sclerosis. International Society of Magnetic Resonance in Medicine 14 th Meeting in Seatle, Washington, USA, May 6-12, 2006. 27. Saksena S, Gupta RK, Hasan KM, Agarwal A, Haris M, Pandey CM, Narayana PA. Focal Walleria

n Degeneration of Corpus Callosum in Large Middle Cerebral Artery Stroke: Serial Diffusion Tensor Imaging. International Society of Magnetic Resonance in Medicine 14 th Meeting in Seatle, Washington, USA, May 6-12, 2006.

28. Haris M, Gupta RK, Husain N, Hasan KM, L. Pal L, Narayana PA. Measurement of DTI metrics in Hemorrhagic Brain Lesions: Its possible implication in imaging interpretation. International Society of Magnetic Resonance in Medicine 14 th Meeting in Seatle, Washington, USA, May 6-12, 2006.

29. Mishra AM, Gupta RK, Nath K, Prasad A, Hasan KM, Prasad KN, Husain M, Husain N, Kumar S,Narayana PA.Diffusion Tensor Fractional Anisotropy is a Potential Surrogate Marker for Neuroinflammatory Molecules in Brain Abscess. International Society of Magnetic Resonance in Medicine 14 th Meeting in Seatle, Washington, USA, May 6-12, 2006.

30. Trivedi R, Malik GK, Gupta RK, Hasan KM, Hasan M, Gupta A, Pandey CM, Narayana PA Serial Quantitative Diffusion Tensor MRI of the Term Neonates with Hypoxic-ischemic Encephalopathy (HIE) International Society of Magnetic Resonance in Medicine 14 th Meeting in Seatle, Washington, USA, May 6-12, 2006.

31. Trivedi R, Gupta A, Malik GK, Gupta RK, Hasan KM, Prasad KN, Narayana PA. Quantitative DTI Assessment of Periventricular White Matter changes in Neonatal Meningitis International Society of Magnetic Resonance in Medicine 14 th Meeting in Seatle, Washington, USA, May 6-12, 2006.

32. Trivedi R, Gupta RK, Agarwal A, Hasan KM, Gupta A, Prasad KN, Narayana PA. Assessment of White Matter Damage in Subacute Sclerosing Panencephalitis using Quantitative Diffusion Tensor MRI International Society of Magnetic Resonance in Medicine 14 th Meeting in Seatle, Washington, USA, May 6-12, 2006.

33. Ashtari M, Hasan KM, Kester H, Ardekani B, Cervellione K, Wu J, McIIree, PR Szesko, Kumra S White Matter Development During Late Adolescence in Healthy Males: A cross-Sectional Diffusion Tensor Imaging Study. International Society of Magnetic Resonance in Medicine 14 th Meeting in Seatle, Washington, USA, May 6-12, 2006.

34. Hasan KM, Linda Ewing-Cobbs and Ponnada A.Narayana. Comparison and Modeling of Entire Brain Same Subject DTI Results at 1.5 T and 3.0 T using Icosahedral Schemes: Application to Normal, Multiple Sclerosis and Pediatric Post Traumatic Brain Injury. Abstract #12, presented at the ISMRM workshop on Methods for Quantitative Diffusion MRI of Human Brain, 13-16 March 2005, Alberta Canada.

35. Hasan KM, Sajja BR, Gupta RK, Wolinsky JS, Narayana PA. Diffusion Tensor Fractional Anisotropy and Compact Fiber Tracking of the Normal-Appearing Seven Segments of the Corpus Callosum in Healthy Adults and Relapsing-Remitting Multiple Sclerosis Patients. Proceedings of the 13th International Society of Magnetic Resonance in Medicine. Miami, Florida 2005, p 652 (Talk).

36. Gupta RA, Hasan KM, Trivedi R, Kanabar BP, Pradhan M, Das V, Parikh NA, Narayana PA Diffusion Tensor Imaging of Developing Human Cerebrum. Proceedings of the 13th International Society of Gupta V, Gupta RK, Saksena S, Hasan KM, Husain M, Trivedi R, Agarwal A, P. A. Narayana. Diffusion Tensor Imaging of Post-traumatic Epilepsy. Proceedings of the 13th International Society of Magnetic Resonance in Medicine. Miami, Florida 2005, p 1379.

37. Gupta RK, Hasan KM, Mishra AM, Jha D, Husain M, Prasad KN, Narayana PA. Does Increased Fractional Anisotropy in Brain Abscess Imply White Matter Tracts on DTI? Proceedings of the 13th International Society of Magnetic Resonance in Medicine. Miami, Florida 2005, p 1351.

38. Magnetic Resonance in Medicine. Miami, Florida 2005, p 292 (Talk).

39. Hahn KR, Prigarin S, Hasan KM. The Feasibility of Diffusion Tensor Imaging for the Human Brain at 1 mm3 Resolution. Proceedings of the 13th International Society of Magnetic Resonance in Medicine. Miami, Florida 2005, p161 (Talk).

40. Kanabar BP, Hasan KM, Sajja BR, Narayana PA. A Diffusion Tensor Imaging based semi-automated segmentation and subdivision of the human corpus callosum: correlation of anisotropy and callosal area and application to gender based differences. Proceedings of the 13th International Society of Magnetic Resonance in Medicine. Miami, Florida 2005, p 1347.

41. Moeller F, Hasan KM, Steinberg JL, Kramer LA, Narayana PA. DTI: Relationship to Behavior in Cocaine Dependence. Proceedings of the 13th International Society of Magnetic Resonance in Medicine. Miami, Florida 2005, p1383.

42. Sundberg LM, Grill RJ, A. Deo, Hasan KM, Narayana PA. DTI - Histology Correlation in Spinal Cord. Proceedings of the 13th International Society of Magnetic Resonance in Medicine. Miami, Florida 2005, p2375.

43. Hou P, Hasan KM, Sitton CW,Wolinsky JS, Narayana PA. Quantitative Analysis of Contrast Efficiency of Phase Sensitive T1IR and Its Primary Applications to Neuroimaging. Proceedings of the 13th International Society of Magnetic Resonance in Medicine. Miami, Florida 2005, p 2811.

44. Sundberg LM, Grill RJ, A. Deo, Hasan KM, Narayana PA. DTI - Histology Correlation in Spinal Cord. Presented at the 2005 University of Texas Medical School Graduate School Competition.

45. Hasan KM, Patel VK, Ewing-Cobbs L, Moeller GF, Steinberg JL, Wolinsky JW, Narayana PA. Mapping the entire human brain in 5 minutes using optimized diffusion tensor imaging: Toward building in vivo a digital fiber atlas of the developing, normal and pathological brain. Tenth Annual Neuroscience Poster Session. University of Texas at Houston (Nov 19, 2004), #116.

46. Moeller FG, Hasan KM, Steinberg JL,Narayana PA, D.M. Dougherty DM, L.A. Kramer LA, Santos RM, Swann AC, Barratt ES. Corpus Callosum White Matter Integrity as Measured by Diffusion Tensor Imaging is Related to Impulsivity in Cocaine-Dependent Subjects. P 464.1. Society of Neuroscience, 2004.

47. Moeller FG, Steinberg JL, Dougherty DM, Hasan KM, Swann AC, Narayana P, Renshaw PF, Kramer LA, Barratt ES. Brain neurobiology related to impulsivity: Risk factor or consequence of cocaine dependence? INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY 7: S310-S310 Suppl. 1, JUN 2004.

48. Steinberg JL, Moeller FG, Hasan KM, Narayana PA, Dougherty DM, Kramer L, Renshaw PF (USA). Functional magnetic resonance imaging and diffusion tensor imaging in cocaine dependence. Presentation at World Psychiatric Association International Congress. Treatments in Psychiatry: an Update, Florence, Italy. November 10-13, 2004.

49. Hasan KM Applications of Diffusion Tensor Imaging of the Entire Human Brain (Invited Talk). University of Texas at Houston Medical School Research Retreat 2004. The Woodlands, Texas February 13, 2004.

50. Hasan KM. Current Research Issues in Water Diffusion Tensor Mapping using Magnetic Resonance Imaging. Biostatistics Seminar, UT School of Public Health (Invited Talk, March 22, 2004).

51. Hasan KM, Bhavik P. Kanabar, Rafeal M. Santos RM, Ewing-Cobbs L, Narayana PA. Age Dependence of the Fractional Anisotropy of Genu and Splenium of Human Corpus Callosum Using Optimized DT-MRI. Proc. 12th International Society of Magnetic Resonnance (ISMRM talk) in Kyoto, Japan, p338 (2004).

52. Hasan KM, Kanabar BP, Rafael M. Santos RM, Kramer L, Mary Prasad, Narayana PA, Ewing-Cobbs L. Diffusion Tensor MRI after Pediatric Brain Injury. Proc. 12th International Society of Magnetic Resonance in Medicine Meeting in Kyoto, Japan, p1350, (2004).

53. Hasan KM, Kanabar BP, Santos RM, Wolinsky JS, Narayana PA. Diffusion Tensor MRI Regional Fractional Anisotropy as a surrogate to detect Axonal Damage in Multiple Sclerosis. Proc.12th International Society of Magnetic Resonance in Medicine Meeting May in Kyoto, Japan, p1498 (2004).

54. Hahn KR, Prigarin S and Hasan KM. A novel Denoising Technique for very noisy diffusion tensor MRI data. Proc. 12th International Society of Magnetic Resonance in Medicine Meeting May 2004 in Kyoto, Japan, p1208 (2004).

55. Kramer LA, Hasan KM, Vu TT. Dynamic Contrast MR of Hepatic Hemangiomas: Evaluation of Temporal Signal Intensity Changes. Proc. 12th International Society of Magnetic Resonance in Medicine Meeting May 2004 in Kyoto, Japan, p2617 (2004).

56. Field AS, Wu YJ, Alexander AL, Wu YC, Hasan KM. Duncan ID. Axial and Radial Components of the Diffusion Tensor in the Myelin Mutant Shaking Pup. 12th International Society of Magnetic Resonance in Medicine Meeting in Kyoto, Japan, p722 (2004).

57. Steinberg JL, Frederick G. Moeller, Ponnada A. Narayana, Donald M. Dougherty, Khader M. Hasan, Larry A. Kramer LA, Renshaw PF. Functional MRI of MDMA Users and Control Subjects During Delayed Memory Task 12th International Society of Magnetic Resonance in Medicine Meeting in Kyoto, Japan, p1162 (2004).

58. Hasan KM and Narayana PA. A novel Multi-faceted Icosahderal Diffusion Tensor Encoding Scheme for mapping the full Human Brain in Ten Minutes. Tenth Annual Neuroscience Poster Session. University of Texas at Houston (Dec 6, 2003)

59. Ewing-Cobbs L, Hasan KM, Kramer L, Prasad M, Narayana PA. Diffusion Tensor MRI after Pediatric Brain Injury: Relation to Cognitive Outcome 32nd Annual meeting of the International Neuropsychological Society, Baltimore, MD (Feb 5, 2004).

60. Moeller, FG, Dougherty, DM, Hasan, KM, Swann, AC, Narayana, PA, Renshaw, PF, Kramer, LA, Barratt, ES. Brain Neurobiology Related to Impulsivity: Risk Factor or Consequence of Cocaine Dependence? International Journal of Neuropsychopharmacology Supp. Vol. 7, June, 2004 pg. S310. (Poster Presentation at the XXIV CINP Congress, Paris, France)

61. Kanabar BP, Santos RM, Narayana PA, Hasan KM. Diffusion Tensor MRI Analysis Tools for Visualization and Quantification of Brain Tissue Microstructure. Tenth Annual Neuroscience Poster Session. University of Texas at Houston (December 6, 2003)

62. Hasan KM, Narayana PA. Computation of the ADC, Relative and Fractional Anisotropy maps in DT-MRI without a Diffusion Tensor Model. Proc. of the 11th ISMRM, Toronto p 2142. (2003).

63. Hasan KM, Narayana PA. A Novel Multi-Faceted Icosahedral Diffusion Tensor Encoding Scheme for Mapping the Full Human Brain in 10 Minutes. World Congress on Medical Physics and Biomedical Engineering p1060 (2003).

64. Hasan KM, Narayana PA. Theoretical, Technical and Computational Issue in Water Diffusion Tensor Magnetic Resonance Imaging of the Full Human Brain. Houston Society for Engineering, Biology and Medicine (April 4, 2003, invited)

65. Hasan KM, Narayana PA. Diffusion Tensor Imaging of the Human Brain: A Potential Technique for Mapping White Matter Fibers. 9th Annual UTHSC Research Day, Houston, TX. (Nov. 2002).

66. Zegarra S, Field A, Alexander A, Hasan KM, Arfanakis K, Badie B: Diffusion Tensor Imaging and Tractography of Cerebral White Matter: Review of Fiber Tract Anatomy and Tumor Imaging Patterns. Annual Meeting of the Radiological Society of North America. Chicago, IL. Magna Cum Laude (Dec. 2002)

67. Hasan KM, Arfanakis, K, Alexander AL. A Referenceless, Balanced and Efficient Encoding Scheme for Diffusion Tensor Imaging. Proc. of the 10th ISMRM, Honolulu p 1107 (2002).

68. Alexander AL, Hasan KM, Arfakanis K, Witwer BP, Field AS, Moftakhar R, Seshmuk P, Haughton, V, Rowley, H, Noyes J, Hermann, B., Meyrend, ME, Badie B. Assessment of Tumor/White Matter Interaction with Diffusion Tensor MRI” Proc. of the 10th ISMRM, Honolulu p 2077 (2002).

69. Hasan KM, Alexander AL Diffusion Tensor Encoding Strategies: Optimization and Considerations. ISMRM DTI Workshop, Saint-Malo, p 210-213 (2002).

70. Field AS, Alexander, AL, Hasan KM, Arfakanis K, Witwer, BP, Moftakhar R, Deshmukh P, Haughton V, Rowley H, Noyes J, Hermann B, Meyerand ME, Badie B. Diffusion-Tensor MR Imaging Patterns in White Matter Fiber Tracts Altered By Neoplasm. ISMRM DTI Workshop, Saint-Malo p 137 (2002).

71. Wilbur BS, Hasan KM, Alexander AL, Parker DL. Optimal Sampling for 3D Projection Reconstruction Imaging. Proc. of the 9th ISMRM, Glasgow p. 682 (2001).

72. Sato T, Hasan KM, and Alexander AL. An Algorithm for White Matter Connectivity in the Human Brain Using Projected Diffusion Tensor Distance. Proc. of the 9th ISMRM, Glasgow p.1520 (2001).

73. Lazar M, Hasan KM, Alexander AL. Bootstrap Analysis of DT-MRI Tractography Techniques: Streamlines and Tensorlines. Proc. of the 9th ISMRM, Glasgow p.1527 (2001).

74. Hasan KM, Parker DL, Roberts J, Alexander AL. Comparison of Optimization Procedures for Diffusion-Tensor Encoding Directions. Proc. of the 8th ISMRM, Denver p.792 (2000).

75. Hasan KM, Parker DL, Alexander AL. Bootstrap Analysis of DT-MRI Encoding Techniques Proc. of the 8th ISMRM, Denver p. 789 (2000).

76. Alexander AL, Hasan KM, Kindlman G, Parker DL,Tsuruda JA. Geometric Analysis of Diffusion Tensor Measurements of the Human Brain” Proc. of the 8th ISMRM, Denver p. 86 (2000).

77. Alexander AL, Hasan KM, Lazar M, Tsuruda J, Parker DL. Analysis of Partial Volume Effects in Diffusion-Tensor MRI. Proc. of the 8th ISMRM, Denver p. 781 (2000).

78. Lazar M, Weinstein D. Hasan KM, Alexander AL. Axon Tractography with Tensorlines. Proc. of the 8th ISMRM, Denver p. 482 (2000).

79. Fukuzaki M, Alexander AL, Goodrich C, Hasan KM, Buswell HR, Gullberg GT, Parker DL. The Ability of Line Scan Diffusion Imaging Method" Proc. of the 7th ISMRM Philadelphia p.1833 (1999).

80. Alexander AL, Burr R, Hasan KM, Jones, G, Chong B, and Tsuruda J. A Technique for Functional Localization of the Sensory Motor Cortex with Diffusion Anisotropy. Proc. of the 7th ISMRM Philadelphia p. 326 (1999).

Graduate/Medical Degrees:

Ph.D.:                  University of Utah, Salt Lake City, UT
Medical Physics:
Analysis, Optimization and Evaluation of Water Spin Self-Diffusion Tensor Imaging Encoding and Acquisition Schemes. Dissertation, Department of Physics: Salt Lake City, University of Utah, 2000; 216 p
U of U Marriott Library Catalog: R117.5;2000.H38;
http://wwwlib.umi.com/dxweb/details?doc_no=943273

M.Sc.:                  Brigham Young University, Provo, UT
Surface Physics

B. Sc.:                  Birzeit University, Birzeit, Palestine
Physics

Postgraduate Training:

Keck Laboratory for Functional and Behavioral Imaging: University of Wisconsin, Madison, WI

Staff Assistant:

Jodi Flores

Office Address: The University of Texas Medical School at Houston
                        Department of Diagnostic and Interventional Imaging
                        6431 Fannin Street, MSB 2.130B
                        Houston, TX 77030

Office Phone:    713-500-7678
Office Fax:        713-500-7684

Faculty Biography

Khader M. Hasan, Ph.D.
  • Khader M. Hasan, Ph.D.
    Associate Professor

  • Dept. of Diagnostic and Interventional Imaging
  • University of Texas Medical School at Houston

    6431 Fannin Street
    MSB 2.130B
    Houston, Texas 77030
  • Phone: 713-500-7678
    Fax:       713-500-7684

    Email: Khader.M.Hasan@
    uth.tmc.edu
Khader M. Hasan, Ph.D.