Department of Internal Medicine
Department of Internal Medicine

Rheumatology Research

Major areas of investigative interest focus on the molecular biology and genetics underlying multisystem inflammatory rheumatic and autoimmune diseases, especially systemic lupus erythematosus, scleroderma, Sjogren's syndrome, polymyositis, rheumatoid arthritis and the spondyloarthropathies. State-of-the-art molecular genetic technology and analyses are being used to map susceptibility genes to these diseases and to identify biomarkers of disease activity and prognosis as well as to identify molecular pathways which can be targeted therapeutically.

Examples of our research include (click on study icon see bibliography):

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The The Austro-Anglo-American Spondylitis Consortium
John D. Reveille, M.D., PI

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LASR 21st Century
Lupus, Arthritis, Scleroderma Research into the 21st century
Frank C. Arnett, M.D., PI
Serological and Immunogenetics Database for Research in Scleroderma and Other Autoimmune Connective Tissue Diseases

UTCORT

Centers of Research Translation in Scleroderma Frank C. Arnett MD, PI

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SCOT
Scleroderma Cyclophosphamide or Transplant
(2005-2012)
Maureen D. Mayes, M.D., MPH, PI

Ongoing projects at the UT Houston Division of Rheumatology

TITLE
AGENCY
INVESTIGATOR
The Austro-Anglo-American Spondylitis Consortium
NIH-NIAMS
John D. Reveille, MD
Center of Research Translation in Scleroderma
NIH-NIAMS
Frank C. Arnett, MD
Center for Clinical and Translational Sciences
NIH-NCRR
Frank C. Arnett, MD
Candidate Gene Polymorphisms in Scleroderma: Defining Genetic Susceptibility Factors
DoD
Maureen D. Mayes, MD MPH
The Integrative Studies of Genetic and Environmental Factors in Scleroderma
DoD
Xiadong Zhou, MD
UTSA - COGNITION study in Lupus
NIH
John D. Reveille, MD PI - Robin Brey, MD (UTSA)
UAB Program Project in the Genetics of SLE
NIH-NIAMS
John D. Reveille, MD PI – Robert Kimberly, MD (UAB)

Rheumatology and Clinical Immunogenetics