Rheumatology Research
Major areas of investigative interest focus on the molecular biology and genetics underlying multisystem inflammatory rheumatic and autoimmune diseases, especially systemic lupus erythematosus, scleroderma, Sjogren's syndrome, polymyositis, rheumatoid arthritis and the spondyloarthropathies. State-of-the-art molecular genetic technology and analyses are being used to map susceptibility genes to these diseases and to identify biomarkers of disease activity and prognosis as well as to identify molecular pathways which can be targeted therapeutically.
Examples of our research include (click on study icon see bibliography):
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The Austro-Anglo-American Spondylitis Consortium |
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Centers of Research Translation in Scleroderma Maureen D. Mayes, M.D., MPH, PI |
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Ongoing projects at the UT Houston Division of Rheumatology
TITLE |
AGENCY |
INVESTIGATOR |
| Candidate Gene Polymorphisms in Scleroderma: Defining Genetic Susceptibility Factors | DoD | Maureen D. Mayes, MD MPH |
| Genome-Wide Association Study in Systemic Sclerosis (GWAS) | NIH/NIAMS | Maureen D. Mayes, MD MPH |
| The Integrative Studies of Genetic and Environmental Factors in Scleroderma | DoD | Xiaodong Zhou, MD |
| UTSA - COGNITION study in Lupus UAB Program Project in the Genetics of SLE | NIH | John D. Reveille, MD PI - Robin Brey, MD (UTSA) |
| UAB Program Project in the Genetics of SLE | NIH-NIAMS | John D. Reveille, MD PI – Robert Kimberly, MD (UAB) |
| The Architecture of the HLA Region in Systemic Sclerosis and Ankylosing Spondylitis | NIH/NIAID | Xiaodong Zhou, MD |
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Division of Renal Diseases and Hypertension
The Division of Renal Diseases and Hypertension strives to provide state-of-the-art patient care, innovative teaching, and cutting edge research.
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