Medical errors are a common and expensive problem in the U.S. healthcare system. To address this public health problem, the Institute of Medicine, the general public, and numerous researchers cite the aviation industry as an example for the healthcare industry to follow. We have assembled a multidisciplinary research team that has a track record of developing, translating, and utilizing aviation safety practices in healthcare. The individual projects of the Center are unified by the theme of translating safety practices from aviation to healthcare.