Optimizing Nutrition in Very Low Birth Weight Patients with Prolonged Transition to Full Enteral Feedings
PI: Cody Arnold
Although most very low birth weight (VLBW) newborns are born with appropriate size for gestational age, they grow very poorly between birth and their due dates. Published studies have shown that VLBW infants rarely receive the calories and protein that are needed to support in-utero growth. Protein and calorie deficits are particularly severe in VLBW with a prolonged transition from parenteral (intravenous) to full enteral (gastrointestinal) nutrition. Published research also suggests that individualized computer-assisted prescriptions for parenteral nutrition could safely and effectively reduce the calorie and protein deficit in patients who experience a prolonged transition relative to current practice (i.e. prescriptions using standard solutions or individualized prescriptions formulated with a hand held calculator). The opportunity for improvement can be evaluated in a retrospective chart review study, comparing intravenous calories and protein prescribed to what might have been prescribed in the same fluid volume.
Progress and Outcomes
Data collection is complete. Data analysis and manuscript preparation are in progress.