Jay-Jiguang Zhu, M.D., Ph.D.
Associate Professor, The Vivian L. Smith Department of Neurosurgery
Director, Neuro Oncology
Education & Training
- Undergraduate Degree:
Shandong University, Shandong, China
- Ph.D. in Molecular Biology:
State University of New York, Buffalo, New York
- MDCM:
McGill University, Montreal, Quebec, Canada
- Internship:
Berkshire Medical Center, Pittsfield, Massachusetts
- Residency in Neurology:
Tufts University School of Medicine, Boston, Massachusetts
- Fellowship in Neuro-Oncology:
Massachusetts General Hospital, Boston, Massachusetts
Board Certifications
- American Board of Psychiatry and Neurology
Clinical Studies
- Performing translational researches on identification of effective chemotherapies for primary brain tumors including malignant gliomas, meningiomas, PCNSL and brain metastasis.
Selected Bibliography
- Hwang, S, Eisenberg, RL,Yao, K, Pfannl, R, Mignano, J, Zhu, J. J., Strauss, G, Wu, J. Impact of Gamma Knife after Surgical Resection of Brain Metastases. Neuro-oncology, 2009, pending publication
- Zhu, J. J., Gerstner, ER. Engler D. Mrugala M. Nugent W. Nierenberg K. Hochberg F. Betensky R. Batchelor, TT. High-dose methotrexate for elderly patients with primary CNS lymphoma. Neuro-oncology. 11: 211-215, 2009
- Gaviani, P; Gonzalez, R G.; Zhu, J. J.; Batchelor, T T.; Henson, J W. Central neurogenic hyperventilation and lactate production in brainstem glioma. Neurology. 64(1):166-167, January 11, 2005.
- Wilson J. C., Zhu, J. J., Black P. McL. The p27/Kip1 locus shows no loss of heterozygosity in human pituitary adenomas. 1999. J. of Neuro-Oncology, 44 (1):35-9.
- Zhu, J. J., Maruyama T., Jacoby L. B., Herman J. G., Gusella J. F., Black P. McL. and Wu J. K., Clonal analysis of a case of multiple meningiomas using multiple molecular genetic approaches. 1999. Neurosurgery. 45(2):409-416.
- Le S. Zhu, J. J., Anthony D. Greider C., Black P. McL., Telomerase activity in human gliomas. 1998, Neurosurgery.42:1120-1124.
- Zhu, J. J., Santarius T., Wu X., Tsong J., Guha A., Wu J. K., Hudson T. J. and Black P. McL., Screening for loss of heterozygosity and microsatellite instability in oligodendrogliomas. 1998, Genes, Chromosomes and Cancer. 21:207-216.
- Zhu, J. J., Leon, S., Guo S. Z., Folkerth, R. D., Wu J. K. and Black P. McL., Evidence for Clonal Origin of Neuronal and Glial Neoplastic Cells in Gangliogliomas. 1997, American J. of Pathology, 151, 565-571.
- Kirsch, M., Zhu, J. J. and Black P. McL., Loss of heterozygosity analysis of BRCA-1 and BRCA-2 genes in meningiomas. 1997. Genes, Chromosomes and Cancer, 20:53-59.
- Zhu J., Guo S. Z., Beggs A. H., Dashner K., Olson N., Wu J. K. and Black P. McL., Microsatellite Instability Analysis of Primary Human Brain Tumors. 1996. Oncogene, 12, 1417-1423.