Enhancing Remyelination as a Mechanism for Spinal Cord Repair
The major goal of this project is to test if a combinatory strategy, including blocking inhibitory Notch signaling, increasing expression of growth factor D15A, and transplantation of OPCs will promote remyelination and facilitate functional recovery after spinal cord injury. Funded by NIH/NCRR
Combinatory Strategies to Functional Remyelination after Spinal Cord Injury
The goal of this grant is to examine the roles of active astrocytes on remyelination and to identify the optimal strategies to promote remyelination and functional recovery after the demyelinated and contused injury in rats. Funded by NIH/NINDS
Dr. Cao is setting up the Mission Connect Center at The University of Texas Health Science Center at Houston where he will explore the therapeutic utility of oligodendrocyte-restricted precursor cells, a type of stem cell, to treat people with spinal cord injury. Funded substantially by Mission Connect Foundation.
