Laboratory of Jia Qian Wu, Ph.D.

Welcome to the Jiaqian Wu Lab. We use interdisciplinary approaches including molecular biology, genetics, genomics, proteomics and bioinformatics to study gene expression and transcriptional regulation in stem cells and the nervous system. You can learn more about who we are and what we do if you are interested.

Dr. Jia Qian Wu stands within her laboratory

Dr. Jia Qian Wu stands within her laboratory

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Immunofluorescence labeling of neurons derived from H1 human embryonic stem cells (hESCs). beta-tubulin (TujIII red) labels both immature and mature neurons. Nuclei (blue) are stained by DAPI.

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Isoform specialization—Splicing diversity is the highest in hESCs and decreases when cells commit to neural differentiation.

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TCF7, together with RUNX1, regulates a transcriptional regulatory network.