Research

Current Research projects:

  1. Reach to Grasp: Outfitting the RiceWrist with Grasp Sensing for Robotic Rehabilitation after SCI
    Principal Site Investigator – Dr. Francisco
    $7,000 - 01/01/2011 -12/31/2011
  2. Pre-clinical and clinical testing of FDA-approved compounds for the treatment of neuropathic pain following spinal cord injury.
    Principal Site Investigator – Dr. Francisco
    $ 104,347 -  01/01/11 – 12/31/11
  3. Robotic training of arm and hand movement after spinal cord injury
    - Mission Connect; TIRR Foundation
    Principal Investigator – Dr. Francisco
          $120,000 , 2009-12
  4. Riluzole Study 
    - Mission Connect; TIRR Foundation
    - $75,000 Co-Investigator Dr. Francisco with Dr. Robert G. Grossman (PI) in the Texas Component of NACTN
  5. Traumatic Brain Injury Model Systems Grant
    National Institute for Disability and Rehabilitation Research (NIDRR)
    Dr. Francisco -Co-investigator (5% Effort); Mark Sherer, PhD, Principal Investigator
    $2,151,750.00, Competitive Renewal - Award #H133A70043, October 1, 2007-
    through September 30, 2012
  6. Intrinsic Hand Muscle Strength and Dexterity in Persons with Neurological impairment
    Principal Site Investigator: Gerard E.Francisco, MD
    Funding: UTHealth Department of Physical Medicine and Rehabilitation
  7. A randomized, controlled, open-label, parallel-group, multicenter study to compare the effect of Intrathecal Baclofen Therapy (ITB Therapy) versus Best Medical Treatment (BMT) on severe spasticity in post-stroke patients after 6 months active treatment
    Principal Site Investigator: Gerard E.Francisco, MD
    Funding: Medtronic International Trading Sàrl
  8. A phase III, multicentre, double blind, prospective, randomised, placebo controlled study, assessing the efficacy and safety of Dysport used for the treatment of lower limb spasticity in adult subjects with hemiparesis due to stroke or traumatic brain injury.
    Principal Site Investigator: Gerard E.Francisco, MD
    Funding: IPSEN Pharma SAS
  9. A phase III, prospective, multicentre, open label, extension study, to assess the long term safety and efficacy of repeated treatment of Dysport intramuscular injection in the treatment of lower limb spasticity in adult subjects with spastic hemiparesis due to stroke or traumatic brain injury
    Principal Site Investigator: Gerard E.Francisco, MD
    Funding: IPSEN Pharma SAS
  10. A Phase III, multicentre, prospective, double blind, randomised, placebo controlled study, assessing the efficacy and safety of Dysport intramuscular injections used for the treatment of upper limb spasticity in adult subjects with spastic hemiparesis due to stroke or traumatic brain injury.
    Principal Site Investigator: Gerard E.Francisco, MD
    Funding: IPSEN Pharma SAS
  11. A Phase III, mutlicentre, prospective, open label extension study to assess the long term safety and efficacy of repeated treatment of Dysport intramuscular injections used for the treatment of upper limb spasticity in adult subjects with spastic hemiparesis due to stroke or traumatic brain injury.
    Principal Site Investigator: Gerard E.Francisco, MD
    Funding: IPSEN Pharma SAS
  12. The respiratory-motor coupling
    Principal Investigator – Dr. Li
    Funding: NIH/NINDS R01NS060774, $918,748
    Project period: 7/1/2009 – 6/30/2013
  13. Clinical Application of High-Density surface EMG
    Principal Investigator – Dr. Li; co-Investigator – Dr. Francisco (3% effort)
    Funding: NIH/NICHD/NCMRR R24 HD050821-08, $90,000
    Project period: 7/1/2011 – 6/30/2013
  14. Pathophysiology of Spasticity
    (Dr. Li, Dr. Francisco)
  15. Management of Chronic Neuropathic Pain
    (Dr. Li)