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© Jonathan Ophir, 1974, 1975, 1976, 1977, 1979. 1980, 1981, 1982, 1983, 1984, 1985, 1986, 1987, 1988, 1989, 1990, 1991, 1992, 1993, 1994, 1995, 1996, 1997, 1998, 1999, 2000, 2001, 2002, 2003, 2004, 2005, 2006, 2007. 2008, 2009. You are granted permission for the non-commercial use, reproduction, distribution or display of these documents under the following restrictions. Appropriate credit is given as to its source and authorship. This permission is valid for a period of 45 (forty five) days from the time this document was obtained from wwww.elastography.com. All other rights reserved by the author(s). It is understood that all individuals copying this information will adhere to the terms/constraints invoked by each author's copyright.
   
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1974

Goldstein, A., Ophir, J. and Templeton, A. W.: A computerized ultrasound processing, acquisition and display (CUPAD) system: Research in Ultrasound image generation. Ultrasound in Medicine, Vol. 1, pp. 475-480, Plenum Press, NY, 1974.Download/View PDF file (2.29MB)

Ophir, J., Goldstein, A. and Templeton, A.W.: The CUPAD system real time handling of randomly acquired clinical ultrasound data. Ultrasound in Medicine, Vol. 1, pp. 481-487 Plenum Press, NY, 1974. Download/View PDF file (3.01MB)

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1975

Goldstein, A., Ophir, J. and Templeton, A.W.: Research in ultrasound image generation: A computerized ultrasound processing, acquisition and display system. Acoustic Holography, Vol. 6, pp. 57-70, Plenum Press, NY, 1975.     Download/View PDF file (7.63MB)

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1976

 Ophir, J. and Goldstein, A.: The principles of digital scan conversion and their application to diagnostic ultrasound. Ultrasound in Medicine, Vol. 3B, pp. 1707-1713, Plenum Press, NY, 1976. Download/View PDF file (5.49MB)

Goldstein, A. and Ophir, J.: True amplitude reconstruction in ultrasound image generation. Ultrasound in Medicine, Vol. 3B, pp. 1421-1431, Plenum Press, NY, 1976. Download/View PDF file (7.11MB)

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1977

 Ophir, J. and Goldstein, A.: A versatile active attenuator for wideband and narrowband applications in ultrasound pulse echo systems. IEEE Trans. Biomed. Engr., Vol 24, No. 2, pp. 186-187, March 1977. Download/View PDF file (4.48MB)

Ophir, J.: A computer based medical ultrasound B-scan system. Doctor of Engineering thesis, University Microfilms, Ann Arbor, Michigan, 1977.  

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1979

 Ophir, J. and Maklad, N.F.: Characterization of medical ultrasonic transceivers. Ultrasound in Medicine and Biology, Vol. 5, pp. 69-73, August, 1979. Download/View PDF file (3.65MB)

Ophir, J. and Maklad, N.F.:  Digital Scan Converters in Diagnostic Ultrasound Imaging.  Proceedings of the IEEE, vol. 67, No. 4, pp. 654-664, April 1979.  Download/View PDF file (18.7MB)

Ophir, J., McWhirt, R.E. and Maklad, N.F.: Aqueous solutions as potential ultrasonic contrast agents. Ultrasonic Imaging, Vol. 1, No. 3, pp. 365-379, July, 1979. Download/View PDF file (18.5MB)

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1980

 Ophir, J., Gobuty, A., McWhirt, R.E. and Maklad, N.F.: Ultrasonic backscatter from contrast producing collagen microspheres. Ultrasonic Imaging, Vol. 2, No. 1, pp. 67-77, January 1980. Download/View PDF file (10.5MB)

Cook, L., Cook, P., Lee, L., Batnitsky, S., Wong, B., Fritz, S., Ophir, J., Dwyer, S., Bigongiari, L. and Templeton, A.: An algorithm of volume estimation based on polyhedral approximation. IEEE Trans. of Biomed. Engineering, Vol. BME-27, No. 9, pp. 493-533, September 1980. 

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1981

 Tyler, T.D., Ophir, J. and Maklad, N.F.: In vivo enhancement of ultrasonic image luminance by aqueous solutions with high speed of sound. Ultrasonic Imaging, Vol. 3, pp. 323-329, 1981. Download/View PDF file (6.01MB)

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1982

Ophir, J. and Jaeger, P.: A ternary solution for acoustic impedance and speed of sound matching to biological tissues. Ultrasonic Imaging, Vol. 4, No. 2, pp. 163-170, April 1982. Download/View PDF file (3.37MB)

Ophir, J. and Jaeger, P.: Spectral shifts of ultrasonic propagation through media with nonlinear dispersive attenuation. Ultrasonic Imaging, Vol. 4, No. 3, pp. 282-289, 1982. Download/View PDF file (5.62MB)

Ophir, J., Maklad, N.F. and Bigelow, R.H.: Ultrasonic attenuation measurements of in vivo human muscle. Ultrasonic Imaging, Vol. 4, No. 3, pp. 290-295, July 1982. Download/View PDF file (3.67MB)

Ophir, J. and Brinch, J.M.: Moiré undersampling artifacts in digital ultrasound. Ultrasonic Imaging, Vol. 4, pp. 311-320, 1982.  Download/View PDF file (5.98MB)

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1983

Narayana, P.A. and Ophir, J.: Spectral shifts of ultrasonic propagation: A study of theoretical and experimental models. Ultrasonic Imaging, Vol. 5, pp. 22-29, 1983. Download/View PDF file (5.84MB)

Narayana, P.A. and Ophir, J.: A closed form method for the measurement of attenuation in nonlinearly dispersive media. Ultrasonic Imaging, Vol. 5, pp. 17-21, 1983. Download/View PDF file (3.0MB) 

Narayana, P.A. and Ophir, J.: On the validity of the linear approximation in the parametric measurement of attenuation in tissues. Ultrasound in Medicine and Biology, Vol. 9 (4), pp. 357-361, 1983. Download/View PDF file (5.03MB) 

Ophir, J. and Narayana, P.A.: Effect of half-wavelength membranes on the axial resolution of real-time ultrasonic scanners. J. Acoust. Soc. Am., Vol. 74, pp. 687-690, 1983. Download/View PDF file (4.56MB)

Narayana, P.A. and Ophir, J.: On the frequency dependence of attenuation in normal and fatty liver. IEEE Transactions on Sonics and Ultrasonics, Vol. SU-30 (6), pp. 379-383, 1983. Download/View PDF file (539 KB)

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1984

Ophir, J.: Parametric vs nonparametric measurements in tissues with nonlinear frequency dependent attenuation. Ultrasound in Medicine & Biology, Vol. 10 (6), pp. 709-713, 1984. Download/View PDF file (5.37MB) 

Ophir, J.:  Attenuation Estimation in Reflection: Progress and Prospects, Ultrasonic Imaging, 6, pp.349-395, 1984.  Download/View PDF file (32.7MB)

Narayana, P.A., Ophir, J. and Maklad, N.F.: The attenuation of ultrasound in biological fluids. J. Acoust. Soc. Am., 76 (1), pp. 1-4, 1984. Download/View PDF file (5.71MB)

Narayana, P.A. and Ophir, J.: The measurement of attenuation in non-linearly attenuating media by the zero-crossing method. Ultrasound in Medicine & Biology, Vol. 10 (6), pp. 715-718, 1984. Download/View PDF file (3.31MB)

Maklad, N.F., Ophir, J. and Balsara, V.: Attenuation of ultrasound in normal liver and diffuse liver disease in vivo. Ultrasonic Imaging, Vol. 6, pp. 117-125, 1984. Download View PDF file (8.21MB)

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1985

Ophir, J., McWhirt, R.E., Maklad, N.F. and Jaeger, P.M.: A narrowband pulse echo technique for in vivo ultrasonic attenuation estimation. IEEE Trans. Biomed. Eng., BME-32, No. 3, pp. 205-212, 1985. Download/View PDF file (10.6MB) 

Ophir, J. and Maklad, N.F.: Range dependent variance artifacts in narrowband estimation of in vivo liver attenuation. IEEE Trans. Sonics and Ultrasonics SU-32 (3), pp. 465-472, 1985. Download/View PDF (825 KB)

Ophir, J., Ghouse, M.A. and Ferrari, L.A.: Attenuation estimation with the zero crossing technique: Phantom studies. Ultrasonic Imaging, Vol. 7, pp. 122-132, 1985. Download/View PDF file (6.84MB)

Ophir, J., Gobuty, A., Maklad, N.F., Tyler, T., Jaeger, P. and McWhirt, R.E.: Quantitative assessment of in vivo backscatter enhancement from gelatin microspheres. Ultrasonic Imaging, Vol. 7, pp. 293-299, 1985. Download/View PDF file (5.51MB)

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1986

 Ophir, J.: Effect of quadratic frequency dependent absorption on ultrasonic spectra. J. Acoust. Soc. Am., 79 (4), pp. 1184-1185, 1986.  Download/View PDF file (3.56MB)

Ophir, J.: Estimation of the speed of ultrasound propagation in biological tissues: A beam tracking method. IEEE Trans. on Ultrasonics, Ferroelectrics and Frequency Control, Vol. UFFC-33 (4), pp. 359-368, 1986. Download/View PDF file (12.6MB) 

Robinson, D.E., Bamber, J.C., Doust, B., Fukuda, M., Greenleaf. J.F., Lizzi, F., Ophir, J., Reid, J.M., Thijssen, J.M. and Wilson, L.S.: Tissue Characterization at WFUMB '85. Ultrasound in Medicine and Biology, Vol. 12 (9), pp. 725-728, 1986. Download/View PDF file (5.56MB)

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1987

 Kontonassios, T. and Ophir, J.: Variance reduction of speed of sound estimation in tissues using the beam tracking method. IEEE Trans. Ultrason., Ferroelect. and Freq. Cont., Vol. UFFC-34, No. 5, pp. 524-530, 1987. Download/View PDF file (8.66MB)

Lin, T.S., Ophir, J. and Potter, G.: Frequency dependent ultrasonic differentiation of normal and diffusely diseased liver. J. Acoust. Soc. Am., Vol. 82 (4), pp. 1131-1138, 1987. Download/View PDF file (11.9MB)

Lin, T.S., Ophir, J. and Potter, G.: Correlations of sound speed with tissue constituents in normal and diffuse liver disease. Ultrasonic Imaging, Vol. 9 (1), pp. 29-40, 1987. Download/View PDF file (6.16MB)

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1988

 Ophir, J. and Lin, T.S.: A calibration free method for measurement of sound speed in biological tissue samples. IEEE Trans. Ultrason., Ferroelect. and Freq. Cont., Vol. 35 (5), pp. 573-577, 1988. Download/View PDF file (4.74MB)

Lin, T., Ophir, J. and Potter, G.: Correlation of ultrasonic attenuation with pathologic fat and fibrosis in liver disease. Ultrasound in Med. and Biol., Vol. 14 (8), pp. 729-734, 1988.  Download/View PDF file (5.97B)

Ophir, J. and Mehta, D.: Elimination of diffraction error in acoustic attenuation estimation via axial beam translation. Ultrasonic Imaging, Vol. 10, pp. 139-152, 1988. Download/View PDF file (7.57MB) 

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1989

 Ophir, J. and Parker, K. J.:  Constrast Agents in Diagnostic Ultrasound. Ultrasound in Med. & Biol., vol. 15, no. 4, pp. 319-333, 1989.  Download/View PDF file (21.7MB)

Ophir, J., Yazdi, Y., Lin, T.S. and Shattuck, D.P.: Optimization of speed of sound estimation from noisy ultrasonic signals. IEEE Trans. Ultrason., Ferroelect. and Freq. Cont., Vol. 36, (1) pp. 16-24, 1989. Download/View PDF file (8.47MB)

Ophir, J., Johnson, W., Yazdi, Y., Shattuck, D.P. and Mehta, D.: Correlation artifacts in speed of sound estimation in scattering media. Ultrasound in Med and Biol., Vol. 15 (4), pp. 341-353, 1989. Download/View PDF file (10.3MB)

Shattuck, D.P., Ophir, J., Johnson, G.W., Yazdi, Y. and Mehta, D.: Correction of refraction and other angle errors in beam tracking speed of sound estimation using multiple tracking transducers. Ultrasound in Med. and Biol., Vol. 15 (7), pp. 673-681, 1989. Download/View PDF file (9.29MB)

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1990

Ophir, J. and Yazdi, Y.: A Transaxial compression technique (TACT) for localized pulse echo estimation of sound speed in biological tissues. Ultrasonic Imaging, Vol. 12, pp. 35-46, 1990. Download/View PDF file (7.22MB)

Céspedes, I. and Ophir, J.: Diffraction Correction Methods for pulse echo acoustic attenuation estimation. Ultras. Med. and Biol., Vol. 16 (7), pp. 707-717, 1990.  Download/View PDF file (9.17MB)

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1991

 Ophir, J., Moriya, T. and Yazdi, Y.: A single-transducer transaxial compression technique for pulse echo estimation of sound speed. Ultrasonic Imaging, Vol. 13 (3), pp. 269-279, July 1991. Download/View PDF file (5.85MB) 

Ophir, J., Céspedes, I., Ponnekanti, H., Yazdi, Y. and Li, X: Elastography: a method for imaging the elasticity of biological tissues. Ultrasonic Imaging, Vol 13 (2), pp. 111-134, 1991. Download/View PDF file (26.5MB)

Robinson, D. E., Ophir, J., Wilson, L. S., and Chen, C. F.:  Pulse-echo ultrasound speed measurements: Progress and Prospects.  Ultrasound in Med. & Bio., vol. 17, no. 6, pp. 633-646, 1991. Download/View PDF file (15.2MB)

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1992

 Céspedes, I., Ophir, J. and Huang, Y.: On the feasibility of sound speed estimation in small regions: simulation studies. J. Ultras. Med. Biol., Vol. 18 (3), pp. 283-291, 1992. Download/View PDF file (8.5MB)

Céspedes, I. and Ophir, J.: Correction of diffraction errors in attenuation estimation with dynamic beam translation. J. Ultras. Med. Biol., Vol. 18 (2), pp. 213-218, 1992. Download/View PDF file (6.71MB)

Ponnekanti, H., Ophir, J. and Céspedes, I: Axial stress distributions between coaxial compressors in elastography: an analytical model. J. Ultras. Med. Biol., Vol. 18 (8), pp. 667-673, 1992. Download/View PDF file (7.02MB)

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1993

 Céspedes, I., Ophir, J., Ponnekanti, H. and Maklad, N. F.: Elastography: elasticity imaging using ultrasound with application to muscle and breast in vivo Ultrasonic Imaging, Vol. 15 (2), pp. 73-88, 1993. Download/View PDF file (17.0MB)

Céspedes, I. and Ophir, J.: Reduction of image noise in elastography. Ultrasonic Imaging, Vol. 15 (2), pp. 89-102, 1993.  Download/View PDF file (8.82MB)

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1994

 Ophir, J., Miller, R.K., Ponnekanti, H., Céspedes, I. and Whittaker, A.: Elastography of beef muscle. J. Meat Science, Vol. 36, pp. 239-250, 1994. Download/view PDF file (9.0MB)

Ponnekanti, H., Ophir, J. and Céspedes, I: Ultrasonic imaging of the stress distribution in elastic media due to an external compressor. J. Ultras. Med. Biol., Vol 20 (1), pp. 27-33, 1994. Download/View PDF file (8.87MB)

Belaid, N., Céspedes, I., Thijssen, J. and Ophir J.: Lesion Detection in Simulated Elastographic and Echographic Images: A Psychophysical Study. J. Ultras. Med. Biol.,Vol. 20(6), pp. 877-891, 1994. Download/View PDF file (23.1MB)

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1995

Ponnekanti, H., Ophir, J., Huang, Y. and Céspedes, I.: Fundamental mechanical limitations on the visualization of elasticity contrast in elastography. J. Ultras. Med. Biol., Vol. 21, pp. 533-543, 1995. Download/View PDF file (13.7MB)

Céspedes, I., Huang, Y., Ophir, J. and Spratt, S.: Methods for the estimation of subsample time-delays of digitized echo signals. Ultrasonic Imaging, Vol. 17, pp. 142-171, 1995. Download/View PDF (15.0MB)

Céspedes, I., Insana, M.S. and Ophir, J.: Theoretical bounds on strain estimation in elastography. IEEE Trans. Ultrasonics, Ferroelectrics and Frequency Control, Vol. 42 (5), 1995. Download/View PDF file (4.09MB)

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1996

Kallel, F. and Bertrand, M.: Tissue Elasticity Reconstruction Using Linear Perturbation Method.  IEEE Transactions on Medical Imaging, vol. 15, no. 3, June 1996.  Download/View PDF file (20.01MB)

Kallel, F., Bertrand, M. and Ophir, J.: Fundamental limitations on the contrast-transfer efficiency in elastography: an analytic study. J. Ultras. Med. and Biol, Vol. 22 (4), pp. 463-470, 1996. Download/View PDF file (7.54MB)

Konofagou, E. E., Dutta, P., Ophir, J. and Céspedes, I.,: Reduction of stress nonuniformities by apodization of compressor displacement in elastography. J. Ultras. Med. and Biol., Vol. 22 (9), pp. 1229-1236, 1996. Download/View PDF file (8.59MB)

Ophir, J., Céspedes, I., Garra, B., Ponnekanti, H., Huang, Y. and Maklad, N.: Elastography:ultrasonic imaging of tissue strain and elastic modulus in vivo.  European Journal of Ultrasound, Vol. 3 (1996), pp. 49-70. Download/View PDF file (23.9MB)

Ophir,J., Céspedes, I., Maklad, N., Ponnekanti, H. Ultrasonic Tissue Characterization: Chapter 7: Elastography: A Method for Imaging the Elastic Properties of Tisue in vivo. 1996. Download/View PDF File (4 MB)

Varghese, T., Ophir, J. and Céspedes, I.: Noise reduction in elastograms using temporal stretching with multicompression averaging. Ultrasound Med. Biol., Vol. 22 (8), pp. 1043-1052, 1996. Download/View PDF file (11.2MB)

Varghese, T., and Ophir, J.: Performance optimization in elastography: Multicompression with temporal stretching. Ultrasonic Imaging, Vol. 18(3), pp.193-214, 1996. Download/View PDF File (12.2MB)

Varghese, T., and Ophir, J.: Estimating tissue strain from signal decorrelation using the correlation coefficient. Ultrasound Med. Biol., vol. 22 (9), pp. 1249-1254, 1996. Download/View PDF File (6.9MB)

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1997

Alam, S. K. and Ophir, J.: On the use of baseband and RF signal decorrelation as tissue strain estimators. Ultras. Med. and Biol., Vol. 23(9), pp. 1427-1434, 1997. Download/View PDF File (6,525KB)

Alam, S. K. and Ophir, J.: Reduction of signal decorrelation from mechanical compression of tissues by temporal stretching-applications to elastography. Ultrasound in Medicine and Biology, vol 23(1), pp.95-105, 1997. Download/View PDF File (10,311KB)

Céspedes, I., Ophir, J., and Alam, S. K.: The combined effect of signal decorrelation and random noise on the variance of time delay estimation. IEEE Trans. on Ultrason., Ferroelec., & Freq. Contr., Vol. 44(1), pp.220-225, 1997. Download/View PDF File(6,288KB)

Garra, B.S., Céspedes, I., Ophir, J., Spratt, S., Zuurbier, R. A., Magnant, C. M. and Pennanen, M. F.: Elastography of Breast lesions: initial clinical results. Radiology, Vol. 202, pp. 79-86, 1997. Download/View PDF File (18,852KB)

Kallel, F., Varghese, T., Ophir, J. and Bilgen, M.: The nonstationary strain filter in elastography, part II Lateral and elevational decorrelation. J. Ultrasound Med. Biol., Vol. 23(9), pp. 1357-1370, 1997. Download/View PDF File (13,429KB)

Kallel, F. and Ophir, J.: A least squares estimator for elastography. Ultrasonic Imaging, Vol. 19 (3), pp. 195-208, 1997. Download/View PDF File (8,961KB)

Kallel, F., and Ophir, J.: Three-dimensional tissue motion and its effect on image noise in elastography, IEEE Trans. Ultrason., Ferroelec., Freq. Contr., Vol. 44(6), pp. 1286-1296, (1997).  Download/View PDF File (13,429KB)

Konofagou, E. E., Ophir, J., Kallel, F., and Varghese, T.: Elastographic dynamic range expansion using variable applied strains. Ultrasonic Imaging, vol 19(2), pp 145-166, 1997. Download/View PDF File (17,315KB)

Konofagou, E. E., Varghese, T. and Ophir, J.: Variable compressions with RF and baseband processing for dynamic range expansion of elastograms. Invited paper, Japan. J. Medical Ultrasonics, Vol. 24(5), pp.753-760, 1997. Download/View PDF File (12,843KB)

Ophir, J., Kallel, F., Varghese, T., Bertrand, M., Céspedes, I., Ponnekanti, H.:  Elastography: A Systems Approach.  Int. J. Imaging Syst. Technol., 8, pp 89-103, 1997.  Download/View PDF File (18,173KB)

Varghese, T. and Ophir, J.: A theoretical framework for performance characterization of elastography : The Strain Filter. IEEE Trans. Ultrason. Ferroel. Freq. Cont., pp.164-172, 1997. Download/View PDF File (10,969KB)

Varghese, T., and Ophir, J.: Enhancement of echo-signal correlation in elastography using temporal stretching. IEEE Trans. Ultrason. Ferroel. Freq. Cont., pp 173-180, 1997. Download/View PDF File (8,608KB)

Varghese, T., and Ophir, J.: The nonstationary strain filter in elastography, Part I Frequency dependent attenuation. J. Ultrasound Med. Biol., Vol. 23(9), 1343-1356, 1997. Download/View PDF File (12,708KB)

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1998

Alam, S. K. and Ophir, J.: An adaptive strain estimator for elastography, IEEE Trans. UFFC, Vol.45(2), pp. 461-472, 1998. Download/View PDF File (22,575KB)

Alam, S. K., Ophir J., Cespedes, I. and Varghese, T.: A deconvolution filter for improvement of time-delay estimation in elastography. IEEE Trans. UFFC, Vol. 45(6), pp. 1565 - 1572, 1998.  Download/View PDF File (7,595KB)

Kallel, F. and Ophir, J.: Limits on the contrast of stress-concentrations in elastography. Ultrasound in Medicine and Biology, Vol. 24(8), pp.1215-1219, 1998. Download/View PDF File (5,883KB)

Kallel, F., Ophir, J., Magee, K., and Krouskop, T. A.: Elastographic imaging of low-contrast elastic modulus distributions in tissue. Ultras. Med. and Biol., pp. 409-425, 1998.  Download/View PDF File (38,539KB)

Konofagou, E. E. and Ophir, J.: A new elastographic method for estimation and imaging of lateral displacements, lateral strains, corrected axial strains and Poisson's ratios in tissues. Ultrasound in Medicine and Biology, Vol. 24(8), pp. 1183-1199, 1998. Download/View PDF File (24,307KB)

Krouskop, T. A., Wheeler, T. M., Kallel, F., Garra, B. S., and Timothy Hall:  Elastic Moduli of Breast and Prostate Tissues Under Compression.  Ultrasonic Imaging, 20, pp.260-274, 1998.  Download/View PDF File (12,017KB)

Stafford, R. J., Kallel, F., Hazle, J., Cromeens, D., Price, R. and Ophir, J.: Elastographic imaging of thermal lesions in soft-tissue: a preliminary study in-vitro. Ultrasound in Medicine and Biology, Vol. 24(9), pp. 1449-1458, 1998.  Download/View PDF File (16,803KB)

Varghese, T. and Ophir J., Characterization of elastographic noise using the envelope of echo signals. Ultras. Med. and Biol., Vol 24(4), pp 543-555, 1998. Download/View PDF File (18,996KB)

Varghese, T., Bilgen, M. and Ophir, J.: Multiresolution Imaging in elastography. IEEE Trans. Ultrason. Ferroel. Freq. Cont., Vol. 45 (1), pp. 65-75, 1998.  Download/View PDF File (15,779KB)

Varghese, T. and Ophir, J.: An analysis of elastographic contrast-to-noise ratio performance. Ultras. Med & Biol., Vol 24 (6), pp. 915-924, 1998.  Download/View PDF File (11,715KB)

Kallel, F. and Ophir, J.:IEEE Transactions on Ultrasonics, and Ferroelectrics, and Frequency Control, Volume 45,
July 1998 Cover.
Download/View PDF File (40 KB).

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1999

Varghese, T. and Ophir, J.: A Method for Experimental Characterization of the Noise Performance of Elastographic Systems. Ultrasonic Imaging, Vol 21(1), pp. 17-30, 1999. Download/View PDF File (38.6MB)

Berg, E. P., Kallel, F., Hussein, F., Miller, R. K., Kehtarnavaz, N., and Ophir, J., The Use of Elastography to measure quality characteristics of pork semimembranosus muscle. Meat Science, 53, pp 31-35, 1999.  Download/View PDF File (5.92MB)

Kallel, F., Stafford, R.J., Price, R. E., Righetti, R., Ophir, J. and Hazle, J.D.: The Feasibility of Elastographic Visualization of HIFU-Induced Thermal Lesions in Soft-Tissue. Ultras. Med. and Biol., Vol 25(4), pp.641-647, 1999.  Download/View PDF File (3.65MB)

Kallel, F., Price, R. E., Konofagou, E., and Ophir, J.:  Elastographic Imaging of the Normal Canine Prostate In Vitro.  Ultrasonic Imaging 21, 201-215, 1999.  Download/View PDF File (19.7MB)

Konofagou, E. E., Varghese, T., Ophir J. and Alam S. K.: Incoherent and Direct Spectral Strain Estimators in Elastography. Ultras. Med & Biol., vol 25, no. 7, pp1115-1129, 1999.  Download/View PDF File (19.4MB)

Miller, R. K., Ophir, J., Kallel, F., Berg, E. P., Moore, L. L. and Rubio, M.S.: Elastography to estimate beef and pork meat quality. Seminars in Food Analysis, Vol. 4(2), pp. 131-145, May 1999. Download/View PDF File (37.2MB)

Ophir, J., Alam, S. K., Garra, B.S., Kallel, F., Konofagou, E. E., Krouskop, T. A., and Varghese, T.: Elastography: Ultrasonic Estimation and Imaging of the Elastic Properties of Tissues. Journal of Engineering in Medicine, Vol. 213, (H3), pp 203-233, 1999. Download/View Complete PDF File (43.6MB) or if you prefer to download/view the PDF files in three parts: I (16,000KB)   II (14,440KB)  III (14,500KB)

Righetti, R., Kallel, F., Stafford, R.J., Price, R. E., Krouskop, T. A., Hazle J.D. and Ophir, J.: Elastographic Characterization of HIFU-induced lesions in canine livers. Ultras. Med & Biol., Vol. 25 (7), pp. 1099-1113, 1999. Download/View PDF File (639KB)

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2000

Konofagou, E. E., Varghese, T. and Ophir, J.: Theoretical Bounds on the Estimation of Transverse Displacement, Transverse Strain and Poisson's Ratio in Elastography. Ultrasonic Imaging, Volume 22, No. 3, pp. 153-177, July, 2000. Download/View PDF File (249 KB)

Konofagou, E. E., Varghese, T. and Ophir, J.: Spectral Estimators in Elastography. Ultrasonics, Vol. 38, No. 1-8, pp. 412-416, 2000.  Download/View PDF File (282 KB)

Varghese, T., Konofagou, E. E., Ophir, J., Alam, S. K. and Bilgen, M.: Direct Strain Estimation in Elastography Using Spectral Cross-Correlation. Ultrasound in Medicine and Biology, Vol.26, No. 9, pp. 1525-1537, 2000.   Download/View PDF File (458 KB)

Varghese, T., Ophir, J. and Krouskop, T.: Nonlinear Stress-Strain Relationships in Tissue and Their Effect on the Contrast-To-Noise Ratio in Elastograms. Ultrasound in Medicine and Biology, Vol 26, No. 5, pp.839 – 851, 2000.  Download/View PDF File (738 KB)

Konofagou, E.E., Harrigan, T. and Ophir, J.: Shear strain estimation and lesion mobility assessment in elastography. Ultrasonics, Vol. 38 (1-8), ppg. 400-404, March 2000Download/View PDF File (531 KB)

Alam, S. K. and Ophir, J.: The Effect of Nonlinear Signal Transformations on Bias Errors in Elastography. Correspondence, IEEE Trans UFFC, Vol. 47 (1), pp 297-303, January 2000. Download/View PDF File (857 KB)

Alam, S. K., Ophir, J. and Varghese, T,: Elastographic Axial Resolution Criteria: An Experimental Study.? Correspondence, IEEE Trans UFFC, Vol. 47 (1), pp 304-309, January 2000.  Download/View PDF File (584 KB)

Ophir, J., Garra, B., Kallel, F., Konofagou, E. E., Krouskop, T., Righetti, R. and Varghese, T.: Elastographic Imaging. Ultrasound In Medicine and Biology, The Future of Biomedical Ultrasound, Vol. 26, suppl. 1, ppg. S23-S29, 2000. Invited review.   Download/View PDF File (414 KB)

Konofagou, E.E. and Ophir, J.: Precision Estimation and Imaging of Normal and Shear Components of the 3D Strain Tensor in elastography. Physics in Medicine and Biology, Vol. 45, pp. 1553-1563, 2000. Invited paper. Download/View PDF File (270 KB)

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2001

Varghese, T., Ophir, J., Konofagou, E.E., Kallel, F. and Righetti, R.: Tradeoffs In Elastographic Imaging, Ultrasonic Imaging, October 23(4), pp. 216-248, 2001. Download/View PDF File (621 KB)

Varghese, T. and Ophir, J.: Experimental corroboration of the nonstationary strain estimation errors in elastography, Ultrasound in Medicine and Biology, Vol. 27, No. 12, pp. 1677-1682, 2001.  Download/View PDF File (114 KB)\

Kallel, F., Prihoda, C.D. and Ophir, J.: Contrast-transfer efficiency for continuously varying tissue moduli: simulation and phantom validation. Ultrasound in Medicine and Biology, Vol. 27, No. 8, pp. 1115-1125, 2001.  Download/View PDF File (529 KB)

Konofagou, E.E., Harrigan, T.P., Ophir, J. and Krouskop, T.A.: Poroelastography: imaging the poroelastic properties of tissues. Ultrasound in Medicine & Biology, Vol 27 (10), pp 1387-1397, 2001.  Download/View PDF File (2.60 MB)

Varghese, T., Bilgen, M. and Ophir, J.: Phase Aberration Effects in Elastography. Ultrasound in Medicine and Biology. Ultrasound in Medicine and Biology, Vol. 27, No. 6, pp. 819-827, 2001.  Download/View PDF File (327 KB)

Ophir, J., Kallel, F., Varghese, T., Konofagou, E., Alam, K., Krouskop, T., Garra, B. & Righetti, R. Elastography. Comptes Rendus De L'Academie des Sciences, serie IV, No. 8, ppg. 1193 -1212. October 2001.- Optical and Acoustic Imaging of Biological Media. Invited review.  Download/View PDF File

Front-cover Citation; Front cover of Comptes Rendus De L'Academie Des Sciences (French Academy of Sciences, Physics and Astrophysics), Tome 2, Serie IV, No. 8, October 2001. Kidney images (elastogram) from research (with Faouzi Kallel, Ph.D.).  Download/View PDF File (1.21 MB)

Konofagou, E., Garra, B., Ophir, J.: IEEE Transactions on Ultrasonics, and Ferroelectrics, and Frequency Control, Vol. 48 No. 3. May 2001 Cover.   Download/View PDF File (1335 KB)

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2002

Srinivasan, S., Ophir, J., and Alam, S.K.: Elastographic Imaging Using Staggered Strain Estimates. Ultrasonic Imaging, vol. 25, pp. 229-245, 2002.  Download/View PDF File (230 MB)

Srinivasan, S., Kallel, F., Souchon, R. and Ophir, J.: Analysis of an Adaptive Strain Estimation Technique in Elastography. Ultrasonic Imaging, Apr; 24(2), 109-118, 2002.  Download/View PDF File (256 KB)

Souchon, R., Soualmi, L., Bertrand, M., Chapelon, JY., Kallel, F. and Ophir, J.: Ultrasonic Elastography Using Sector Scan Imaging and Radial Compression. Ultrasonics May 40 (1-8): pp. 867-871, May 2002.  Download/View PDF File (274 KB)

Konofagou, E.E., D'hooge, J. and Ophir, J.: Myocardial Elastography - A feasibility study. Ultrasound in Medicine and Biology,Vol. 28, No.4, 2002.  Download/View PDF File (478 KB)

Alaniz, A., Kallel, F., Hungerford, E. and Ophir, J.: Variational method for modeling continuously varying lenses in HIFU, sonography, and sonography-based cross-correlation methods. Journal of Acoustical Society of America. Vol. 111 (1), pt. 1, pp 468-474, Jan. 2002.  Download/View PDF File (381 KB)

Srinivasan, S., Kallel, F. and Ophir, J: Estimating the elastographic signal-to-noise ratio using correlation coefficients. Ultrasound in Medicine and Biology. Mar; 28(3), pp 359-368. 2002.  Download/View PDF File (466 KB)

Righetti, R., Ophir, J. and Ktonas, P.: Axial Resolution in Elastography. Ultrasound in Medicine and Biology. Jan;28(1), pp. 101-113, 2002.  Download/View PDF File (273 KB)

Srinivasan, S., Kallel, F. and Ophir, J.: The effects of digitization on the elastographic signal-to-noise ratio. Ultrasound in Medicine and Biology, Nov.-Dec; 28(11-12), pp. 1521-1534. 2002.  Download/View PDF File (293)

Ophir, J., Alam, S.K., Garra, B.S., Kallel, F., Konofagou, E.E., Krouskop, T., Merritt, C.R.B., Righetti, R., Souchon, R., Srinivasan, S. and Varghese, T.: Elastography: Imaging the Elastic Properties of Soft Tissues with Ultrasound. Journal of Med Ultrasound, Vol. 29, Winter, pp. 155-171, 2002. Invited Review Article. Download/View PDF File (3.64 MB)

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2003

Krouskop, T.A., Younes, P.S., Srinivasan, S., Wheeler, T. and Ophir, J.: Differences in the compressive stress-strain response of infiltrating ductal carcinomas with and without lobular features - implications for mammography and elastography. Ultrasonic Imaging Vol. 25, pp 162-170, 2003.  Download/View PDF File (400 KB)

Souchon, R., Rouviere, O., Gelet, A., Detti, V., Srinivasan, S., Ophir, J. and Chapelon, JY.: Visualization of HIFU Lesions Using Elastography of the Human Prostate In Vivo: Preliminary Results. Ultrasound in Medicine and Biology. Vol. 29, No. 7, pp 1007-1015, 2003.  Download/View PDF File (322 KB)

Madsen, E.L., Frank, G.R., Krouskop, T.A., Varghese, T., Kallel, F. and Ophir, J.: Tissue-Mimicking Oil-in-Gelatin Dispersions for Use in Heterogeneous Elastography Phantoms. Ultrasonic Imaging, Vol. 25, pp. 17-38. 2003.  Download/View PDF File (283 KB)

Fortin, M., Buschmann, M.D., Bertrand, M.J., Foster, F.S. and Ophir, J.: Dynamic Measurement of of Internal Solid Displacement in Articular Cartilage Using Ultrasound Bacscatter. Journal of Biomechanics 36, pp 443-447, 2003.  Download/View PDF File (148 KB)

Bilgen. M., Srinivasan, S., Lachman, L.B., and Ophir, J.:Elastography Imaging of Small Animal Oncology Models: A feasibility Study. Ultrasound in Medicine and Biology, Volume 29, Issue 9, pp 1291-1296, 2003.  Download/View PDF File (304 KB)

Srinivasan, S. and Ophir, J.: A zero-crossing strain estimator in elastography. Ultrasound in Medicine and Biology, vol 29, No. 2, pp 227-238. 2003.  Download/View PDF File (502 KB)

Srinivasan, S., Righetti, R., and Ophir, J.: Tradeoffs between the axial resolution and the signal-to-noise ratio in elastography. Ultrasound in Medicine and Biology, Vol. 29, No. 6, pp. 847-866, 2003.  Download/View PDF File (534 KB)

Righetti, R., Srinivasan, S. and Ophir, J.: Lateral Resolution in Elastography. Ultrasound in Medicine and Biology, Vol. 29, No. 5, pp. 695-704, 2003.  Download/View PDF File (260 KB)

Souchon, R., Curiel, L., Rouvière, O., Gelet, A., Ophir, J. and Chapelon, J-Y: Comparison of US Elastograms and MR Images of Thermal Lesions in the Prostate. WCU, Paris, September 7-10, 2003. Download/View PDF (745 KB)

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2004

Srinivasan, S., Krouskop, T., Ophir, J.: Comparing Elastographic Strain Images with Modulus Images Obtained Using Nano-Indentation: Preliminary Results Using Phantoms and Tissue Samples. Ultrasound in Medicine and Biology, Vol.30, No.3, pp.329-343, 2004.  Download/View PDF File (574 KB)

Righetti, R., Ophir, J., Srinivasan, S. and Krouskop, T.: The Feasibility of Using Elastography for Imaging the Poisson's Ratio in Porous Media. Ultrasound in Medicine and Biology, Vol. 30, No. 2, pp. 215-228, 2004.  Download/View PDF File (692 KB)

Srinivasan, S., Righetti, R. and Ophir, J.: An experimental characterization of elastographic spatial resolution: Analysis of the tradeoffs between spatial resolution and contrast-to-noise ratio. Ultrasound in Medicine and Biology, Vol. 30, No. 10, pp. 1269-1280, 2004. Download/View PDF File (701 KB)

Srinivasan, S., Alam, S.K., and Ophir, J.: Theoretical Derivation of SNR, CNR and spatial resolution for a local-adaptive strain estimator for elastography. Ultrasound in Medicine and Biology, Vol. 30, No. 9, pp. 1185-197, 2004.  Download/View PDF (547 KB)

Srinivasan, S., Krouskop, T. and Ophir, J.: A quantitative comparison of modulus images obtained using nanoindentation with strain elastograms. Ultrasound in Medicine and Biology, Vol. 30, No. 7, pp. 899-918, July 2004. 
Download/View PDF   (1215 KB)

Langevin, H., Konofagou, EE., Badger, G., Churchill, D., Fox, J., Ophir, J. and Garra, BS: Tissue displacements during acupuncture using ultrasound elastography techniques. Ultrasound in Medicine and Biology, Vol. 30. No. 9, pp. 1173-1183, 2004. Download/View PDF (497 KB)

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2005

Righetti, R., Ophir, J. and Krouskop, TA: A method for generating permeability elastograms and poisson's ratio time-constant elastograms. Ultrasound in Medicine and Biology, Vol. 31, No. 6 pp. 803-816. 2005.  Download/View PDF (95 KB)

Hoyt, K., Forsberg, F., Merritt, C.R.B., Liu, J.B. and Ophir, J: In vivo elastographic investigation of ethanol induced hepatic lesions. Ultrasound Med Biology, Vol. 31, No. 5, pp. 607-612, 2005. Download/View PDF (219 KB)

Doyley, MM., Srinivasan, S., Pendergrass, SA., Wu, Z and Ophir, J.: Comparative Evaluation of strain-based and model-based modulus elastography. Ultrasound in Medicine and Biology, Vol. 31, No. 6, pp. 787-802, 2005.
Download/View PDF (7925 KB)

Hoyt, K., Forsberg, F. and Ophir, J: Investigation of parametric spectral estimation techniques for elasticity imaging. Ultrasound In Medicine and Biology,Vol. 31, No. 8, pp. 1109-1121, 2005. Download/View PDF (544 KB)

Doyley, MM, Srinivasan, S, Dimidenko, E, Soni, N, and Ophir, J: Enhancing the perfomance of model-based elastography by incorporating additional a priori information in the modulus image reconstruction process. Physics in Medicine and Biology, 50, pp. 1-18, 2005. Download/View PDF 1.24 MB

ThitaiKumar, A., Ophir, J. and Krouskop, TA: Noise performance and signal-to-noise ratio of shear strain elastograms. Ultrasonic Imaging, 27, pp 145-165. September 2005. Download/View PDF 2.17 MB

Righetti, R., Ophir, J., Chandrasekhar, RM., Garra, BS. And Krouskop, TA: A new method for generating poroelastograms in noisy environments. Ultrasonic Imaging, 27, pp. 181-198, September 2005.
Download/View PDF 4.44 MB

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2006

Hoyt, K., Forsberg, F. and Ophir, J: Comparison of shift estimation strategies in spectral elastogaphy. Ultrasonics 44, pp. 99-108, 2006. Download/View PDF (327 KB)

Hoyt, K., Forsberg, F. and Ophir, J: Analysis of hybrid spectral strain estimation technique in elastography. Physics in Medicine and Biology, Institute of Physics Publishing, 5, pp. 197-209, 2006. Download/View PDF (283 KB)

Chandrasekhar, R., Ophir, J., Krouskop, T. and Ophir, K.: Elastographic image quality vs tissue motion in vivo. Ultrasound in Medicine and Biology, Vol. 32, No. 6, pp. 847-855, 2006. Download/View PDF 455 KB

Thitaikumar, A., Righetti, R., Krouskop, TA. and Ophir, J.: Resolution of axial shear strain elastography. Physics in Medicine and Biology, 51, pp. 5245-5257, 2006.  Download/View PDF (342 KB)

Srinivasan, S., Krouskop, T., Ophir, J.   Comparing nano-indenter-based modulus images with strain elastograms. IEEE TUFFC Cover Page, August, 2006.    Download/View PDF (534 KB)

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2007

Thitalkumar A, Krouskop T, Ophir J. Signal-to-noise ratio, contrast-to-noise ratio, and their tradeoffs with resolution in axial-shear strain elastography. Phys. Med. Biol. 52 (2007) 13-28. Download/View PDF (559 KB)

Righetti R, Righetti M, Ophir J, Krouskop TA. The feasibility of estimating and imaging the mechanical behavior of poroelastic materials using axial strain elastography Physics in Medicine and Biology, Vol. 52, pp. 3241-3259, 2007.
Download/View PDF (908 KB)

ThitaiKumar, A., Krouskop, TA., Garra BS, and Ophir, J.: Visualization of Bonding at an Inclusion Boundary using Axial Shear Strain Elastography: A Feasibility Study. Physics in Medicine and Biology, 52, 2615-2633 (2007).
Download/View PDF (1.75 MB)

Righetti, R., Ophir, J., ThitaiKumar, A. and Krouskop, T.: Assessing image quality in effective Poisson's ratio elastography and poroelastography - part II. Physics in Medicine and Biology. Vol. 52 (2007). pp. 1321-1333. Download/View PDF (463 KB)

Righetti, R., Srinivasan, S., ThitaiKumar, A., Ophir, J. and Krouskop, T.: Assessing image quality in effective Poisson's ratio elastography and poroelastography - part I. Physics in Medicine and Biology, Vol. 52 (2007), pp.1303-1320.
Download/View PDF (298 KB)

ThitaiKumar A., and Ophir, J.; Effect of lesion boundary conditions on Axial Strain Elastograms:
A Parametric Study; Ultrasound in Medicine and Biology Vol. 33, No. 9, pp. 1463-1467 (2007)
Download/View PDF (192 KB)

Righetti R, Garra BS, Mobbs LM, Kraemer-Chant CM, Ophir J, Krouskop TA. The feasibility of using poroelastography techniques for distinguishing between normal and lymphedematous tissues in vivo. Physics in Medicine and Biology (2007), pp. 6525-6541. Download/View PDF (3.37 MB)


2008

Patil, Abhay V.; Krouskop, Thomas A.; Ophir, Jonathan; and Srinivasan, Seshadri. On the differences between two-dimensional and three-dimensional simulations for assessing elastographic image quality: a simulation study. Ultrasound in Medicine and Biology, Volume 34, Number 7, pp. 1129-1138. Download/View PDF (1336 KB)

Thitaikumar, Arun; Ophir, Jonathan; IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, August 2008, vol 55, no. 8. August 2008 Cover. Download / View PDF (2.04 MB)

Arun Thitaikumar, Louise M. Mobbs, Christina M. Kraemer-Chant, Brian S. Garra, and Jonathan Ophir. Breast Tumor Classification using axial shear strain elastography: a feasibility study. Phys. Med. Biol. 53 (2008) 4809-4823.
Download/View PDF (981 KB)


2009

Fehrenbach, Jerome; Thitai-Kumar, Arun; Ophir, Jonathan; and Souchon, Remi. A new method to estimate tissue motion from ultrasonic measurements, with high signal-to-noise ratio and accurate spatial resolution. In press.
Download/View PDF. (192 KB)


2010

Thittai, Arun, Galaz, Belfor and Ophir, Jonathan, Axial-Shear Strain Distributions In An Elliptical Inclusion Model: Experimental Validation And In Vivo Examples With Implications To Breast Tumor Classification. Ultrasound in Med. & Biol., Vol. 36, No. 5, pp. 814-820, 2010
Download/View PDF (2291 KB)

Thittai, Arun K.; Galaz, Belfor; and Ophir, Jonathan. Importance of axial compression verification to correct interpretation of axial-shear strain elastograms in breast lesions. Ultrasonic Imaging, Vol. 32, pp. 190- 198 (2010).
Download/View PDF (1264 KB)


2011

Arun K. Thittai, Jose-Miguel Yamal, Louise M. Mobbs, Christina M. Kraemer-Chant, Srinivasa Chekuri, Brian S. Garra, and Jonathan Ophir. Axial-Shear Strain Elastography For Breast Lesion Classification: Further Results From In Vivo Data. Ultrasound in Med. & Biol., Vol. 37, No. 2, pp. 189–197, 2011.
Download/View PDF (1055 KB)

Thittai, Arun K., Galaz, Belfor and Ophir, Jonathan. Visualization Of HIFU-Induced Lesion Boundaries By Axial-Shear Strain Elastography: A Feasibility Study. Ultrasound in Med. & Biol., Vol. 37, No. 3, pp. 426–433, 2011.
Download/View PDF (854 KB)

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Last Updated January 13, 2009