Scleroderma-related
Publications Since Inception of the Center of
Research
Translation
(formerly the SCOR)
- Tan F, Stivers DN, Chakraborty R, Foster MW, Howard RF,
Milewicz DM, Arnett FC: Association of microsatellite markers near
the fibrillin 1 gene on human chromosome 15q with scleroderma in a
Native American population. Arthritis Rheum. 1998,
41:1729-1737 PubMed
- Tan F, Stivers DN, Arnett FC, Chakraborty R, Howard RF,
Reveille JD: HLA haplotypes and microsatellite polymorphisms in and
around the MHC region in a Native American population with a high
prevalence of scleroderma (systemic sclerosis). Tissue Antigens
1999, 53:74-80 Publication
- Tan FK, Arnett FC, Stephan S, Sinichiro S, Mirachi A, Speira H,
Takeshi S, Shoichi O, LeRoy C, Postlethwaite AE, Bona C: Autoantibodies
to the extra-cellular matrix microfibrillar protein, fibrillin-1 in
patients with scleroderma and other connective tissue diseases. J
Immunol 1999, 163: 1066-1072 Publication
- Arnett FC, Tan FK, Uziel Y, Krafchik BR, Laxer RM, Antohi S,
Bona CA: Autoantibodies to the extracellular matrix microfibrillar
protein, fibrillin-1 in patients with localized scleroderma.
Arthritis Rheum 1999, 42:2656-2659 PubMed
- Tan FK, Arnett FC. Genetic factors in the etiology of
systemic sclerosis and Raynaud phenomenon. Curr Opin Rheumatol.
2000 12:511-9 Publication
- Zhou X, Tan FK, Stivers DN, Arnett FC: Microsatellites and
intragenic polymorphisms of transforming growth factor beta and
platelet derived growth factor and their receptor genes in Native
Americans with systemic sclerosis (scleroderma): a preliminary genetic
analysis showing no genetic association. Arthritis Rheum 2000, 43:
1068-1073 PubMed
- Tan FK, Arnett, FC, Reveille JD, Ahn, C, Antohi, S, Kasturi,
K., Sasaki, T, Nishioka, Bona CA: Autoantibodies to fibrillin-1 in
systemic sclerosis: ethnic differences in antigen recognition and lack
of correlation with specific clincal features or HLA alleles.
Arthritis Rheum 2000, 43: 2464-24 PubMed
- Tan FK, Wang N, Kuwana M, Chakraborty R, Bona C, Milewicz D,
Arnett FC: Association of fibrillin-1 single nucleotide
polymorphisms (SNP) haplotypes with systemic sclerosis in Native
American and Japanese populations. Arthritis Rheum 2001, 44:
893-901 PubMed
- Guo D, Tan FK, Cantu A, Plon SE, Milewicz: FBN1 exon 2
splicing error in a patient with Marfan syndrome. Am J Med Genet
2001, 101: 130-134 Publication
- Wallis DD, Tan FK, Kielty CM, Arnett FC, Milewicz DM: Abnormalities
in fibrillin-1 containing microfibrils in dermal fibroblasts cultures
from patients with systemic sclerosis (scleroderma). Arthritis
Rheum 2001, 44:1855-1864 PubMed
- Tew MB, Reveille JD, Arnett FC, Friedman AW, McNearney T,
Fischbach M, Ahn C, Tan FK: Glutathione-S-transferase genotypes in
systemic sclerosis. Genes Immunity 2001, 2:236-238 Publication
- Johnson RW, Reveille, JD, McNearney T., Fischbach M., Friedman
AF, Ahn C, Arnett FC, Tan FK: Lack of association of a
functionally relevant single nucleotide polymorphism in the
metalloproteinase 1 promoter with systemic sclerosis, Genes
Immunity 2001, 2:273-275 Publication
- Zhou XD, Tan FK, Xiong M, Milewicz DM, Feghali C, Fritzler M,
Arnett FC: Systemic Sclerosis (Scleroderma) - specific autoantigen
genes are selectively over-expressed in scleroderma fibroblasts, J
Immunol 2001, 167:7126-7133 Publication
- Arnett FC, Cho M, Chatterjee S, Aguilar MB, Reveille JD, Mayes
MD. Familial occurrence frequencies and relative risks for systemic
sclerosis (scleroderma) in three United States cohorts. Arthritis
Rheum. 2001 44:1359-1362 PubMed
- Reveille JD, Fischbach M, McNearney T, Friedman AW, Aguilar MB,
Lisse J, Fritzler MJ, Ahn C, Arnett FC; GENISOS Study Group. Systemic
sclerosis in 3 US ethnic groups: a comparison of clinical,
sociodemographic, serologic, and immunogenetic determinants. Semin
Arthritis Rheum. 2001 30:332-46 Publication
- Denton CP, Zheng B, Shiwen X, Zhang Z, Bou-Gharios G,
Eberspaecher H, Black CM, de Crombrugghe B. Activation of a
fibroblast-specific enhancer of the proalpha2(I) collagen gene in
tight-skin mice. Arthritis Rheum. 2001 44:712-22 PubMed
- Tew MB, Arnett FC, Reveille JD, Tan FK: Mutations of
the bone morphogenetic protein receptor 2 (BMPR2) are not found in
patients with pulmonary hypertension and underlying connective tissue
disease. Arthritis Rheum 2002, 46:2829-2830 Publication
- Zhou XD, Tan FK, Reveille JD, Wallis D, Milewicz DM, Ahn C,
Wang A, Arnett FC: Association of novel polymorphims with the
expression of SPARC in normal fibroblasts and with susceptibility to
scleroderma.. Arthritis Rheum 2002, 46: 2990-2999 Publication
- Kodera T, Tan FK, Sasaki T, Arnett FC, Bona CA. Association
of 5'-untranslated region of the Fibrillin-1 gene with Japanese
scleroderma. Gene 2002; 297:61-67 Publication
- Johnson RW, Tew MB, Arnett FC. The genetics of systemic
sclerosis. Curr Rheumatol Rep. 2002 4:99-107 PubMed
- Ahmed SS, Tan FK, Arnett FC. The complex genetics of
scleroderma. Am J Med. 2002 112:584-586 Publication
- Arnett FC: Systemic sclerosis (scleroderma), in Molecular
Pathology of Autoimmunity, 2nd Edition. Edited by AN
Theofilopoulos and CA Bona, Taylor and Francis, New York, 2002, pp
453-469.
- Zhou X, Tan FK, Wang, Chakraborty R, Arnett FC:Genome-wide
association study for systemic sclerosis susceptibility regions in a
Native American population with a high disease prevalence.
Arthritis Rheum 2003, 48: 2585-2592 Publication
- Tan FK, Tercero G, Wang N, Chakraborty R, Arnett FC. Association
of fibrillin-1 single nucleotide polymorphisms (SNP) haplotypes with
systemic sclerosis in Native American and Japanese populations:
Examination of biologically relevant candidates around FBN1,
Arthritis Rheum, 2003 48:3295-3296 Publication
- Reveille JD. Ethnicity and race and systemic sclerosis: how
it affects susceptibility, severity, antibody genetics, and clinical
manifestations. Curr Rheumatol Rep. 2003 ;5:160-167
PubMed
- Ho KT, Reveille JD. The clinical relevance of
autoantibodies in scleroderma. Arthritis Res Ther. 2003 5:80-93.
Epub 2003 Feb 12 Publication
- Tan FK. Systemic sclerosis: the susceptible host (genetics
and environment). Rheum Dis Clin North Am. 2003 29:211-37 PubMed
- Mayes MD. Scleroderma epidemiology. Rheum Dis Clin
North Am. 2003 29:239-254 PubMed
- Mayes MD. Endothelin and endothelin receptor antagonists in
systemic rheumatic disease. Arthritis Rheum. 2003 48:1190-9 Publication
- Mayes MD, Lacey JV Jr, Beebe-Dimmer J, Gillespie BW, Cooper B,
Laing TJ, Schottenfeld D. Prevalence, incidence, survival, and
disease characteristics of systemic sclerosis in a large US population.
Arthritis Rheum. 2003 48 :2246-55 Publication
- Reveille JD, Solomon DH; American College of Rheumatology Ad
Hoc Committee of Immunologic Testing Guidelines. Evidence-based
guidelines for the use of immunologic tests: anticentromere, Scl-70,
and nucleolar antibodies. Arthritis Rheum. 2003 49:399-412 Publication
- Ahmed SS, Tan FK. Identification of novel targets in
scleroderma: update of population studies, cDNA arrays, SNP analysis,
and mutations. Curr Opin Rheumatol. 2003 15:766-71 Publication
- Planque S, Zhou Y, Nishiyama Y, Sinha M, O’Connor-McCourt M,
Arnett F, Paul S: Autoantibodies to the epidermal growth factor
receptor in systemic sclerosis, lupus and autoimmune mice. FASEBJ 2003
17: 136-143, 2003 Publication
- Mayes MD, O'Donnell D, Rothfield NF, Csuka ME. Minocycline
is not effective in systemic sclerosis: results of an open-label
multicenter trial. Arthritis Rheum. 2004 50:553-557 Publication
- Wang N, Zhou X, Tan FK, Foster MW, Arnett FC, Chakraborty R: Genetic
signatures of pre-expansion bottleneck in the Choctaw population of
Oklahoma. Am J Phys Anthropol 2004, 124:373-379 Publication
- Wallis DD, Tan FK, Keasler R, Milewicz DM. Fibrillin-1
abnormalities in dermal fibroblast cultures from first degree relatives
of patients with systemic sclerosis (Scleroderma). Arthritis Rheum
2004, 50:329-332 Publication
- Cepeda EJ, Reveille JD. Autoantibodies in systemic
sclerosis and fibrosing syndromes: clinical indications and relevance.
Curr Opin Rheumatol. 2004 16:723-32
Publication
- Arnett FC, Reveille JD, O’Hanlon TP. HLA-DRB1 alleles in a Caucasian population
from Houston USA. Hum Immunol 2004 65:1238-1241 Publication
- Zhou X, Dimachkie MM, Xiong M, Tan FK, Arnett FC: cDNA microarrays reveal distinct gene
expression clusters in idiopathic inflammatory myopathies. Med
Sci Monit 2004 10: BR191-BR197 Publication
- Zhou X, Tan FK, Guo X, Wallis D, Milewicz DM, Xue S, Arnett FC.
Short interfering RNA inhibition of SPARC attenuates the
profibrotic effect of transforming growth factor b1 in cultured normal
human fibroblasts. Arthritis Rheum 2005 52:257-261
Publication
- Basu D, Reveille JD. Anti-Scl70.
Autoimmunity 2005, 38:65-72 PubMed
- Tan FK, Hildebrand BA, Lester M, Stivers DN, Pounds S, Zhou X,
Wallis DD, Milewicz DM, Reveille JD, Mayes MD, Jin L, Arnett FC. Classification
analysis of the transcriptosome of non-lesional cultured dermal
fibroblasts from scleroderma patients with early disease. Arthritis
Rheum 2005, 52:865-876 Publication
Supplemental
data
- Assasi S, Reveille JD, Arnett FC, Mayes MD, McNearny T,
Fischbach M, Tan FK. Polymorphisms of the endothelial nitric oxide
synthase and angiotensin-converting enzyme show no association with
systemic sclerosis. Am J Med 2005, 118: 907-911 Publication
- Zhou X, Tan FK, Wallis D, Bona C, Milewicz DM, Arnett F: Autoantibodies to fibrillin-1 activate
normal human fibroblasts in culture through the TGF beta pathway and
recapitulate the “scleroderma phenotype” J Immunol, 2005,
175:4555-4560 Publication
- Xiong M, Arnett FC, Feghali-Bostwick CA, Zhou X. A systems biology approach to complex
diseases. FEBS Lett, 2005, 579:5325-5332 Publication
- Zhou XD, Tan FK, Xiong M, Arnett FC, Feghali-Bostwick C. Clinically
discordant scleroderma monozygotic twins show concordance for
fibroblast gene expression profiles. Arthritis Rheum, 2005,
52:3305-3314 Publication
Supplemental
data
- Assassi S, Tan FK. Genetics
of scleroderma: update on SNP analysis and microarrays. Current
Opin Rheumatol, 2005, 17:761-767 Publication
- Tan FK, Zhou X, Mayes MD, Gourh P, Guo X, Marcum C, Jin L,
Arnett FC. Signatures
of differentially regulated interferon gene expression and
vasculotropism in the peripheral blood cells of systemic sclerosis
patients. Rheumatology (Oxford), 2006, 45: 694-702 Publication
Supplemental
data
- Gardner
H, Shearstone J, Bandaru R, Crowell T, Lynes M, Trojanowska M,
Pannu J, Kubo M, Smith E, Jablonlska S, Blaszczyk, Tan FK, Mayes
MD. Gene
profiling of scleroderma skin reveals robust signatures of disease
which are imperfectly reflected in the transcript profiles of explanted
fibroblasts. Arthritis Rheum 2006, 43:1961-1973 Publication
- Tan, F. K. Autoantibodies
against PDGF Receptor in Scleroderma. N Engl
J Med 2006, 354: 2709-2711 Publication
- Tashkin DP, Elashoff R, Clements PJ, Goldin J, Roth MD, Furst
DE, Arriola E, Silver R, Strange C, Bolster M, Seibold JR, Riley DJ,
Hsu VM, Varga J, Schraufnagel DE, Theodore A, Simms R, Wise R, Wigley
F, White B, Steen V, Read C, Mayes M, Parsley E, Mubarak K, Connolly
MK, Golden J, Olman M, Fessler B, Rothfield N, Metersky M; Scleroderma
Lung Study Research Group. Cyclophosphamide
versus placebo in scleroderma lung disease. N Engl J Med, 2006
354:2655-2666 Pubmed
- Ahmed SS, Tan FK, Arnett FC, Jin L, Geng YJ. Induction of
apoptosis and fibrillin 1 expression in human dermal endothelial cells
by scleroderma sera containing anti-endothelial cell antibodies.
Arthritis Rheum, 2006 54:2250-2262 Publication
- Zhou X, Tan FK, Guo X, Arnett FC. Attenuation of collagen
production with small interfering RNA of SPARC in cultured fibroblasts
form the skin of patients with scleroderma. Arthritis Rheum,
2006
54:2626-2631 Publication
- Arnett, FC. Is
scleroderma an autoantibody mediated
disease? Curr Opin Rhematol, 2006 18: 579-581 Publication
- Zhou XD, Xiong M, Tan FK, Guo XJ, Arnett FC. SPARC, an upstream regulator of connective
tissue growth factor to transforming growth factor beta stimulation. Arthritis Rheum, 2006
54:3885-3889 Publication
- Gourh P, Tan FK, Assassi S, Ahn CW. McNearney TA,
Fischbach M, Arnett FC, Mayes MD. Association of the PTPN22
R620W polymorphism with topoisomerase I and centromere autoantibody
positive systemic sclerosis. Arthritis Rheum 2006, 54:3945-2953 Publication
- Sonnylal S, Denton CP, Zheng B, Keene DR, He R, Adams HP,
Vanpelt CS, Geng YJ,Deng JM, Behringer RR,de Crombrugghe B. Postnatal induction of transforming growth
factor beta signaling in fibroblasts of mice recapitulates clinical,
histologic, and biochemical features of scleroderma. Arthritis
Rheum. 2007 56:334-44 Publication
- Mcnearny TA, Reveille JD, Fischbach M, Friedman AF, Lisse JR,
Goel N, Tan FK, Zhou X, Ahn C, Feghali-Bostwick CA,
Fritzler M, Arnett FC, Mayes MD. Pulmonary
involvement in systemic
sclerosis: Associations with genetic, serologic, sociodemographic, and
behavioral factors. Arthritis Care Res, 2007 57: 318-326 Publication
- Alkassab F, Gourh P, Tan FK, McNearny T, Fischbach M, Ahn C,
Arnett FC, Mayes MD. An allograft
inflammatory factor 1 (AIF1) single
nucleotide polymorphism (SNP) is associated with anticentromere
antibody positive systemic sclerosis. Rheumatology (Oxford),
2007 Publication
- Assassi S, Arnett FC, Reveille JD, Gourh P, Mayes MD. Clinical, immunologic, and genetic
features of familial systemic sclerosis. Arthritis Rheum, 2007
56: 2031 - 2037 Publication
- Goruh P, Mayes MD, Arnett FC. CTGF
polymorphism associated with systemic sclerosis. N Engl J Med,
2008 358:308-309 Publication
- Agarwal SK, Tan FK, Arnett FC. Genetics and Genomic studies in
scerloderma (systemic sclerosis). Rheum Dis Clin N Am, 2008
34:17-40 Publication
- Xiong M, Arnett FC, Guo X, Xiong H, Zhou X. Differential dynamic properties of
scleroderma fibroblasts in response to environmental stimuli. PLoS
ONE, 2008 3:e1693 Publication
- Kim D, Peck A, Santer
D, Patole P, Schwartz S. Molitor JA, Arnett FC, Elkon K. Induction
of interferon-a by
scleroderma sera containing autoantibodies to
topoisomerase I: Association of higher interferon-a activity with lung
fibrosis. Arthritis Rheum, 2008 58:2174-2182 Publication