Figure 1. Hierarchical clustering of PBC (genes and samples)

The genes panel used here were the 382 genes differentially expressed at a conditional false discovery rate of ≤ 0.10 (p<0.006). Centered correlation metric and average linkage clustering was used.  The genes comprising several clusters of interest (#15, #27, #37, #64 and #71) are shown to the right of the heatmap. rSSc - scleroderma PBCs; rC - matched control PBCs

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PBC_cluster