Pathway Comparison Results

Description of the problem:

Number of classes: 2
Column of the Experiment Descriptors sheet that defines class variable: Group
Number of genes used for random variance estimation: 8541
Number of genes that passed filtering criteria: 8541
Number of investigated pathways: 426 Broad/MIT
Random variance model was used

Pathways which have more genes differentially expressed among the phenotype classes than expected by chance:

Table - The first 21 Pathway are significant at the nominal 0.005 level of the LS permutation test or KS permutation test (sorted by p-values of the LS permutation test).


	Broad Pathway	Pathway description	Number of genes	LS Permutation p-value	KS Permutation p-value
1	h_egfPathway	The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.	11	0.0001781	0.0007173
2	h_at1rPathway	Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.	19	0.0004368	0.0095861
3	h_igf1Pathway	BioCarta	9	0.0006275	0.0004011
4	h_ghPathway	BioCarta	11	0.0010702	0.0324908
5	h_pyk2Pathway	BioCarta	17	0.0011765	0.0104516
6	h_spryPathway	BioCarta	7	0.0012316	0.0038862
7	MAPK_Cascade_h	GO	10	0.0012932	0.0167688
8	h_radiation_sensitivity	BioCarta	20	0.0013331	0.0149414
9	h_insulinPathway	BioCarta	9	0.0014628	0.0090869
10	h_cellcyclePathway	Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.	17	0.0016052	0.004197
11	HOXA9_DOWN_h	Dorsam_et_al_2004	25	0.0016679	0.0428986
12	h_gata3Pathway	BioCarta	8	0.0022081	0.0692661
13	h_ctla4Pathway	T cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APCs CD80 or 86.	11	0.0027336	0.0673271
14	cell_cycle_checkpointII_h	GO	7	0.0031081	0.0028034
15	h_g1Pathway	BioCarta	17	0.0042274	0.0077604
16	EMT_UP_h	Jechlinger_et_al_2003	32	0.0042758	0.0361
17	h_tumor_supressor	BioCarta	15	0.0044661	0.0847671
18	h_drug_resistance_and_metabolism	BioCarta	62	0.0045301	0.0571057
19	h_pmlPathway	BioCarta	10	0.0048356	0.0997659
20	h_EGF_receptor_signaling_pathway	BioCarta	9	0.0071864	0.0032054
21	GPCRs_Class_A_Rhodopsin-like_h	GO	58	0.0716031	0.0022145

The significant genes can be found by clicking the link here.

Pathways which discriminate among classes by running the Hotelling T-square test for testing the hypothesis that for each pathway no genes in the set are differentially expressed between classes:

The number of principal components: 3

Table - The first 109 pathways are significant at the nominal 0.005 level of the Hotelling T-square test (sorted by p-values).


	Broad Pathway	Pathway description	Number of genes	Hotelling test p-value
1	h_spryPathway	BioCarta	7	1.1e-06
2	h_ST_p38_MAPK_Pathway	Signalling Transduction KE	20	6.9e-06
3	EMT_UP_h	Jechlinger_et_al_2003	32	1.34e-05
4	h_egfPathway	The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.	11	1.92e-05
5	h_insulinPathway	BioCarta	9	3.63e-05
6	h_igf1Pathway	BioCarta	9	3.67e-05
7	h_il6Pathway	BioCarta	10	5.91e-05
8	GLUCOSE_DOWN_h	Peng_et_al_2002	89	6.99e-05
9	h_ghPathway	BioCarta	11	9.38e-05
10	h_il2rbPathway	BioCarta	22	9.39e-05
11	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	24	9.47e-05
12	h_pdgfPathway	BioCarta	12	0.0001013
13	h_igf1rPathway	BioCarta	8	0.0001044
14	MAPK_Cascade_h	GO	10	0.0001361
15	FRASOR_ER_DOWN_h	Frasor_et_al_2004	37	0.0001462
16	SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h	SignallingAlliance	13	0.0001492
17	h_mapkPathway	BioCarta	54	0.0001557
18	MAP00010_Glycolysis_Gluconeogenesis_h	GenMAPP	23	0.0001634
19	h_pyk2Pathway	BioCarta	17	0.0001722
20	h_mta3Pathway	BioCarta	5	0.0001966
21	h_gata3Pathway	BioCarta	8	0.0002448
22	h_fcer1Pathway	In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.	19	0.0002452
23	h_metPathway	BioCarta	16	0.0002699
24	cell_motility_h	Any process involved in the controlled movement of a cell.	58	0.0002877
25	ca_nf_at_signalling_h	GEArray	58	0.0002992
26	h_nfatPathway	BioCarta	29	0.0003129
27	h_il3Pathway	BioCarta	8	0.0003487
28	FETAL_LIVER_HS_ENRICHED_TF_JP_h	Manually Curated	46	0.0004007
29	h_epoPathway	Erythropoietin, which activates the MAPK pathway, stimulates erythrocyte production and is an effective treatment for anemia.	8	0.0004264
30	h_nthiPathway	BioCarta	15	0.0004378
31	HOXA9_DOWN_h	Dorsam_et_al_2004	25	0.0004546
32	fmlppathway_h	The fMLP receptor is a G-protein coupled receptor in neutrophiles that recognizes formylated bacterial peptides and activates NADPH oxidase.	20	0.0004828
33	h_at1rPathway	Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.	19	0.000559
34	h_tumor_supressor	BioCarta	15	0.0005798
35	NFKB_INDUCED_h	Hinata_et_al_2003	60	0.000606
36	DNA_DAMAGE_SIGNALLING_h	GO	66	0.0006144
37	GPCRs_Class_A_Rhodopsin-like_h	GO	58	0.0007054
38	MAP00230_Purine_metabolism_h	GenMAPP	50	0.0007068
39	h_raccycdPathway	BioCarta	15	0.0007662
40	h_stressPathway	BioCarta	15	0.0008401
41	MAP00190_Oxidative_phosphorylation_h	GenMAPP	20	0.0009015
42	h_atrbrcaPathway	BRCA1 and 2 block cell cycle progression in response to DNA damage and promote double-stranded break repair; mutations induce breast cancer susceptibility.	12	0.0009417
43	EMT_DOWN_h	Jechlinger_et_al_2003	21	0.0009966
44	h_ngfPathway	BioCarta	8	0.0010117
45	CR_TRANSCRIPTION_FACTORS_h	PNAS_2013	46	0.0011226
46	h_erkPathway	Cell growth is promoted by Ras activation of the anti-apoptotic p44/42 MAP kinase pathway.	17	0.0011573
47	h_ST_G_alpha_i_Pathway_	Signalling Transduction KE	20	0.0011874
48	h_tpoPathway	BioCarta	8	0.0012393
49	h_gleevecPathway	BioCarta	12	0.0012794
50	h_il2Pathway	BioCarta	13	0.0013664
51	h_pparaPathway	BioCarta	34	0.0014403
52	GNF_FEMALE_GENES_h	na	50	0.0016619
53	MAP00510_N_Glycans_biosynthesis_h	GenMAPP	11	0.0016653
54	CR_PROTEIN_MOD_h	PNAS_2010	96	0.0017479
55	h_p27Pathway	BioCarta	10	0.0017628
56	SA_PTEN_PATHWAY_h	SigmaAldrich	10	0.0018065
57	CR_TRANSPORT_OF_VESICLES_h	PNAS_2015	18	0.002019
58	h_il1rPathway	BioCarta	15	0.002075
59	h_tollPathway	BioCarta	19	0.0022275
60	MAP00240_Pyrimidine_metabolism_h	GenMAPP	29	0.0023595
61	h_g2Pathway	BioCarta	18	0.002402
62	h_gabaPathway	BioCarta	5	0.002409
63	h_keratinocytePathway	BioCarta	26	0.0024116
64	h_lairPathway	BioCarta	9	0.0024136
65	MAP00030_Pentose_phosphate_pathway_h	GenMAPP	11	0.0024356
66	ANDROGEN_UP_GENES_h	na	32	0.0025209
67	h_SIG_InsulinReceptorPathwayInCardiacMyocytes	SignallingAlliance	29	0.0025548
68	h_crebPathway	CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling.	14	0.0027324
69	h_ST_JNK_MAPK_Pathway	Signalling Transduction KE	24	0.0027719
70	h_radiation_sensitivity	BioCarta	20	0.0027867
71	h_mtorPathway	BioCarta	14	0.0028072
72	h_glycolysisPathway	BioCarta	5	0.0029056
73	shh_lisa_h	Manually Curated	13	0.0030194
74	h_ST_G_alpha_5_Pathway	Signalling Transduction KE	7	0.0030305
75	h_ptdinsPathway	BioCarta	16	0.0030497
76	h_insulin_signalling	BioCarta	58	0.0030521
77	h_biopeptidesPathway	Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases.	19	0.0030677
78	h_ST_Ga13_Pathway	Signalling Transduction KE	25	0.0031494
79	h_ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway	Signalling Transduction KE	22	0.0031671
80	cell_adhesion_h	The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules.	97	0.0032822
81	h_ceramidePathway	Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type.	16	0.0033054
82	h_eea1Pathway	The FYVE-finger proteins EEA1 and HRS are localized to endosome membranes and regulate sorting and ubiquitination in the vesicle transport system.	7	0.0033393
83	ST_B_Cell_Antigen_Receptor_h	Signalling Transduction KE	24	0.0033761
84	h_tidPathway	BioCarta	9	0.0033789
85	DOWNREG_BY_HOXA9_h	Manually Curated	22	0.0034111
86	ST_GRANULE_CELL_SURVIVAL_PATHWAY_h	Signalling Transduction KE	19	0.0035205
87	h_bcrPathway	B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen.	17	0.0035561
88	h_egfr_smrtePathway	EGF receptor activation inhibits SMRT, a transcriptional co-repressor that interacts with transcription factor complexes and gene silencers.	6	0.0035752
89	HEMO_TF_LIST_JP_h	Manually Curated	45	0.0036197
90	h_hcmvPathway	BioCarta	11	0.0036815
91	MAP00051_Fructose_and_mannose_metabolism_h	GenMAPP	12	0.003728
92	MAP_kinase_kinase_activity_h	GenMAPP	5	0.0038348
93	LEU_UP_h	Peng_et_al_2002	77	0.0038565
94	h_p53Pathway	BioCarta	11	0.0038582
95	h_ppargPathway	BioCarta	6	0.0038969
96	h_ST_ERK1_ERK2_MAPK_Pathway	Signalling Transduction KE	20	0.0039951
97	MAP00710_Carbon_fixation_h	GenMAPP	8	0.004022
98	h_drug_resistance_and_metabolism	BioCarta	62	0.0040238
99	h_il10Pathway	BioCarta	7	0.0041077
100	h_rbPathway	BioCarta	9	0.0041223
101	h_mprPathway	BioCarta	14	0.0041417
102	h_S1P_Signaling	BioCarta	17	0.0042391
103	MAP00600_Sphingoglycolipid_metabolism_h	GenMAPP	8	0.0043908
104	h_ST_Differentiation_Pathway_in_PC12_Cells	Signalling Transduction KE	24	0.0044761
105	h_integrinPathway	BioCarta	24	0.0046608
106	h_longevityPathway	BioCarta	5	0.0047172
107	h_p53_signalling	BioCarta	58	0.0048118
108	ST_ADRENERGIC_h	Signalling Transduction KE	24	0.0048368
109	h_ptenPathway	BioCarta	9	0.004882

The significant genes can be found by clicking the link here.

Table - Significant pathway which have more genes differentially expressed among the phenotype classes than expected by chance consist of the following genes (sorted by p-values).


	Broad Pathway	Pathway description	Unique id	Anno- tations	Description	Clone	GB acc	UG cluster	Gene symbol	Defined genelists	Parametric p-value	Geometric mean of ratios (class Disesase /class Normal )
1	egfPathway_h	The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.	H002040_01	Info	Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)	H002040_01	X00588	77432	EGFR	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degredation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc	0.0004362	0.669
2	egfPathway_h	The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.	H002186_01	Info	Serum response factor (c-fos serum response element-binding transcription factor)	H002186_01	J03161	155321	SRF	EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription	0.0017465	0.722
3	egfPathway_h	The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.	H002055_01	Info	Growth factor receptor-bound protein 2	H002055_01	M96995	296381	GRB2	Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...	0.0022348	1.459
4	egfPathway_h	The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
5	egfPathway_h	The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.	H003611_01	Info	Mitogen-activated protein kinase kinase 4	H003611_01	L36870	75217	MAP2K4	Perou's- Intrinsic- Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system	0.012502	0.753
6	egfPathway_h	The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.	H001365_01	Info	Protein kinase C, beta 1	H001365_01	X07109	77202	PRKCB1	Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbal Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction	0.0304335	1.379
7	egfPathway_h	The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.	H003178_01	Info	Mitogen-activated protein kinase 3	H003178_01	X60188	861	MAPK3	Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...	0.0986041	1.184
8	egfPathway_h	The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.	H001600_01	Info	RAS p21 protein activator (GTPase activating protein) 1	H001600_01	M23379	758	RASA1	EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction	0.1015906	0.844
9	egfPathway_h	The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.	H003158_01	Info	Mitogen-activated protein kinase 8	H003158_01	L26318	190913	MAPK8	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...	0.1287835	1.166
10	egfPathway_h	The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.	H001349_01	Info	Janus kinase 1 (a protein tyrosine kinase)	H001349_01	M64174	50651	JAK1	EGF Signaling Pathway, IFN alpha signaling pathway, IFN gamma signaling pathway , IL 2 signaling pathway, IL 4 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, PDGF Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction	0.2754104	1.129
11	egfPathway_h	The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.	H002722_01	Info	Mitogen-activated protein kinase kinase 1	H002722_01	L11284	3446	MAP2K1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...	0.7377933	0.973
12	at1rPathway_h	Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.	H002040_01	Info	Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)	H002040_01	X00588	77432	EGFR	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degredation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc	0.0004362	0.669
13	at1rPathway_h	Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.	H002055_01	Info	Growth factor receptor-bound protein 2	H002055_01	M96995	296381	GRB2	Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...	0.0022348	1.459
14	at1rPathway_h	Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
15	at1rPathway_h	Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.	H003006_01	Info	Serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 8	H003006_01	K02215	3697	SERPINA8	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Angiotensin-converting enzyme 2 regulates heart function, Bioactive Peptide Induced Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, immunology	0.0063778	1.296
16	at1rPathway_h	Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.	H002573_01	Info	Protein tyrosine kinase 2 beta	H002573_01	U43522	20313	PTK2B	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CXCR4 Signaling Pathway, IL-7 Signal Transduction, Ion Channel and Phorbal Esters Signaling Pathway, Links between Pyk2 and Map Kinases, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Thrombin signaling and protease-activated receptors, angiogenesis, immunology, signal_transduction	0.0091935	1.367
17	at1rPathway_h	Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.	H003611_01	Info	Mitogen-activated protein kinase kinase 4	H003611_01	L36870	75217	MAP2K4	Perou's- Intrinsic- Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system	0.012502	0.753
18	at1rPathway_h	Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.	H003493_01	Info	MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B)	H003493_01	X63380	78881	MEF2B		0.0145042	1.328
19	at1rPathway_h	Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.	H001992_01	Info	Activating transcription factor 2	H001992_01	X15875	198166	ATF2	ALK in cardiac myocytes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , The 4-1BB-dependent immune response, The information-processing pathway at the IFN-beta enhancer	0.0178377	0.749
20	at1rPathway_h	Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.	H001365_01	Info	Protein kinase C, beta 1	H001365_01	X07109	77202	PRKCB1	Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbal Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction	0.0304335	1.379
21	at1rPathway_h	Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.	H003178_01	Info	Mitogen-activated protein kinase 3	H003178_01	X60188	861	MAPK3	Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...	0.0986041	1.184
22	at1rPathway_h	Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.	H002287_01	Info	P21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related)	H002287_01	U24152	62402	PAK1	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, FAS signaling pathway ( CD95 ), fMLP induced chemokine gene expression in HMC-1 cells, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Rac 1 cell motility signaling pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, TNFR1 Signaling Pathway	0.1104284	0.815
23	at1rPathway_h	Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.	H003158_01	Info	Mitogen-activated protein kinase 8	H003158_01	L26318	190913	MAPK8	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...	0.1287835	1.166
24	at1rPathway_h	Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.	H002501_01	Info	Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	H002501_01	D25274	173737	RAC1	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signalling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments	0.1980127	1.118
25	at1rPathway_h	Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.	H002112_01	Info	PTK2 protein tyrosine kinase 2	H002112_01	L13616	740	PTK2	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Apoptotic Signaling in Response to DNA Damage, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, CCR3 signaling in Eosinophils, Cell to Cell Adhesion Signaling, CXCR4 Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, HIV-I Nef: negative effector of Fas and TNF, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Phospholipids as signalling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Trefoil Factors Initiate Mucosal Healing, uCalpain and friends in Cell spread, VEGF, Hypoxia, and Angiogenesis, angiogenesis, signal_transduction	0.2346929	0.896
26	at1rPathway_h	Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.	H002405_01	Info	Mitogen-activated protein kinase kinase 2	H002405_01	L11285	72241	MAP2K2	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor	0.3118803	1.093
27	at1rPathway_h	Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.	H011336_01	Info	Guanine nucleotide binding protein (G protein), q polypeptide	H011336_01	U43083	296261	GNAQ	Activation of PKC through G protein coupled receptor, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CCR3 signaling in Eosinophils, CXCR4 Signaling Pathway, Effects of calcineurin in Keratinocyte Differentiation, G-Protein Signaling Through Tubby Proteins, Links between Pyk2 and Map Kinases, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase, Signaling Pathway from G-Protein Families, Thrombin signaling and protease-activated receptors, immunology	0.3713616	0.89
28	at1rPathway_h	Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.	H002722_01	Info	Mitogen-activated protein kinase kinase 1	H002722_01	L11284	3446	MAP2K1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...	0.7377933	0.973
29	at1rPathway_h	Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.	H002404_01	Info	Synaptotagmin I	H002404_01	M55047	154679	SYT1		0.8170962	0.971
30	at1rPathway_h	Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.	H000579_01	Info	Calmodulin 2 (phosphorylase kinase, delta)	H000579_01	D45887	182278	CALM2		0.9689776	1.004
31	igf1Pathway_h	BioCarta	H000732_01	Info	Insulin receptor substrate 1	H000732_01	S62539	96063	IRS1	Perou's- Intrinsic- Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology	0.0013348	0.643
32	igf1Pathway_h	BioCarta	H002186_01	Info	Serum response factor (c-fos serum response element-binding transcription factor)	H002186_01	J03161	155321	SRF	EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription	0.0017465	0.722
33	igf1Pathway_h	BioCarta	H002055_01	Info	Growth factor receptor-bound protein 2	H002055_01	M96995	296381	GRB2	Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...	0.0022348	1.459
34	igf1Pathway_h	BioCarta	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
35	igf1Pathway_h	BioCarta	H002473_01	Info	Insulin-like growth factor 1 receptor	H002473_01	NM_000875	239176	IGF1R	Perou's- Intrinsic- Breast-Cancer-Genes, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Erk1/Erk2 Mapk Signaling pathway, IGF-1 Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Telomeres, Telomerase, Cellular Aging, and Immortality, The IGF-1 Receptor and Longevity, immunology	0.079692	1.158
36	igf1Pathway_h	BioCarta	H003178_01	Info	Mitogen-activated protein kinase 3	H003178_01	X60188	861	MAPK3	Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...	0.0986041	1.184
37	igf1Pathway_h	BioCarta	H001600_01	Info	RAS p21 protein activator (GTPase activating protein) 1	H001600_01	M23379	758	RASA1	EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction	0.1015906	0.844
38	igf1Pathway_h	BioCarta	H003158_01	Info	Mitogen-activated protein kinase 8	H003158_01	L26318	190913	MAPK8	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...	0.1287835	1.166
39	igf1Pathway_h	BioCarta	H002722_01	Info	Mitogen-activated protein kinase kinase 1	H002722_01	L11284	3446	MAP2K1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...	0.7377933	0.973
40	ghPathway_h	BioCarta	H000732_01	Info	Insulin receptor substrate 1	H000732_01	S62539	96063	IRS1	Perou's- Intrinsic- Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology	0.0013348	0.643
41	ghPathway_h	BioCarta	H002186_01	Info	Serum response factor (c-fos serum response element-binding transcription factor)	H002186_01	J03161	155321	SRF	EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription	0.0017465	0.722
42	ghPathway_h	BioCarta	H002055_01	Info	Growth factor receptor-bound protein 2	H002055_01	M96995	296381	GRB2	Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...	0.0022348	1.459
43	ghPathway_h	BioCarta	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
44	ghPathway_h	BioCarta	H002890_01	Info	Ribosomal protein S6 kinase, 90kD, polypeptide 1	H002890_01	L07597	149957	RPS6KA1	Cell Cycle: G2/M Checkpoint, Erk1/Erk2 Mapk Signaling pathway, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, MAPKinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Role of Erk5 in Neuronal Survival, Transcription factor CREB and its extracellular signals, Phosphatidylinositol signaling system	0.0138896	1.42
45	ghPathway_h	BioCarta	H001365_01	Info	Protein kinase C, beta 1	H001365_01	X07109	77202	PRKCB1	Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbal Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction	0.0304335	1.379
46	ghPathway_h	BioCarta	H003178_01	Info	Mitogen-activated protein kinase 3	H003178_01	X60188	861	MAPK3	Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...	0.0986041	1.184
47	ghPathway_h	BioCarta	H002624_01	Info	Insulin receptor	H002624_01	X02160	89695	INSR	Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Growth Hormone Signaling Pathway, Insulin Signaling Pathway, immunology	0.433218	0.919
48	ghPathway_h	BioCarta	H002261_01	Info	Signal transducer and activator of transcription 5B	H002261_01	U47686	244613	STAT5B		0.441402	1.071
49	ghPathway_h	BioCarta	H009068_01	Info	Homo sapiens mRNA; cDNA DKFZp586N1323 (from clone DKFZp586N1323)	H009068_01	AL080218	24064			0.509279	1.056
50	ghPathway_h	BioCarta	H002722_01	Info	Mitogen-activated protein kinase kinase 1	H002722_01	L11284	3446	MAP2K1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...	0.7377933	0.973
51	pyk2Pathway_h	BioCarta	H003200_01	Info	Mitogen-activated protein kinase kinase 3	H003200_01	D87116	180533	MAP2K3	fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway	0.0009666	1.561
52	pyk2Pathway_h	BioCarta	H002055_01	Info	Growth factor receptor-bound protein 2	H002055_01	M96995	296381	GRB2	Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...	0.0022348	1.459
53	pyk2Pathway_h	BioCarta	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
54	pyk2Pathway_h	BioCarta	H002895_01	Info	Mitogen-activated protein kinase 14	H002895_01	L35263	79107	MAPK14	BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAPKinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm ...	0.0086925	1.429
55	pyk2Pathway_h	BioCarta	H002573_01	Info	Protein tyrosine kinase 2 beta	H002573_01	U43522	20313	PTK2B	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CXCR4 Signaling Pathway, IL-7 Signal Transduction, Ion Channel and Phorbal Esters Signaling Pathway, Links between Pyk2 and Map Kinases, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Thrombin signaling and protease-activated receptors, angiogenesis, immunology, signal_transduction	0.0091935	1.367
56	pyk2Pathway_h	BioCarta	H003611_01	Info	Mitogen-activated protein kinase kinase 4	H003611_01	L36870	75217	MAP2K4	Perou's- Intrinsic- Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system	0.012502	0.753
57	pyk2Pathway_h	BioCarta	H003332_01	Info	V-crk avian sarcoma virus CT10 oncogene homolog-like	H003332_01	X59656	37078	CRKL	IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, Signaling of Hepatocyte Growth Factor Receptor, tsonc	0.0164206	0.675
58	pyk2Pathway_h	BioCarta	H001365_01	Info	Protein kinase C, beta 1	H001365_01	X07109	77202	PRKCB1	Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbal Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction	0.0304335	1.379
59	pyk2Pathway_h	BioCarta	H003178_01	Info	Mitogen-activated protein kinase 3	H003178_01	X60188	861	MAPK3	Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...	0.0986041	1.184
60	pyk2Pathway_h	BioCarta	H002287_01	Info	P21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related)	H002287_01	U24152	62402	PAK1	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, FAS signaling pathway ( CD95 ), fMLP induced chemokine gene expression in HMC-1 cells, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Rac 1 cell motility signaling pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, TNFR1 Signaling Pathway	0.1104284	0.815
61	pyk2Pathway_h	BioCarta	H003158_01	Info	Mitogen-activated protein kinase 8	H003158_01	L26318	190913	MAPK8	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...	0.1287835	1.166
62	pyk2Pathway_h	BioCarta	H002501_01	Info	Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	H002501_01	D25274	173737	RAC1	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signalling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments	0.1980127	1.118
63	pyk2Pathway_h	BioCarta	H002405_01	Info	Mitogen-activated protein kinase kinase 2	H002405_01	L11285	72241	MAP2K2	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor	0.3118803	1.093
64	pyk2Pathway_h	BioCarta	H011336_01	Info	Guanine nucleotide binding protein (G protein), q polypeptide	H011336_01	U43083	296261	GNAQ	Activation of PKC through G protein coupled receptor, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CCR3 signaling in Eosinophils, CXCR4 Signaling Pathway, Effects of calcineurin in Keratinocyte Differentiation, G-Protein Signaling Through Tubby Proteins, Links between Pyk2 and Map Kinases, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase, Signaling Pathway from G-Protein Families, Thrombin signaling and protease-activated receptors, immunology	0.3713616	0.89
65	pyk2Pathway_h	BioCarta	H002722_01	Info	Mitogen-activated protein kinase kinase 1	H002722_01	L11284	3446	MAP2K1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...	0.7377933	0.973
66	pyk2Pathway_h	BioCarta	H002404_01	Info	Synaptotagmin I	H002404_01	M55047	154679	SYT1		0.8170962	0.971
67	pyk2Pathway_h	BioCarta	H000579_01	Info	Calmodulin 2 (phosphorylase kinase, delta)	H000579_01	D45887	182278	CALM2		0.9689776	1.004
68	spryPathway_h	BioCarta	H002040_01	Info	Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)	H002040_01	X00588	77432	EGFR	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degredation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc	0.0004362	0.669
69	spryPathway_h	BioCarta	H002055_01	Info	Growth factor receptor-bound protein 2	H002055_01	M96995	296381	GRB2	Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...	0.0022348	1.459
70	spryPathway_h	BioCarta	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
71	spryPathway_h	BioCarta	H002847_01	Info	Protein tyrosine phosphatase, receptor type, B	H002847_01	X54131	123641	PTPRB	Sprouty regulation of tyrosine kinase signals, cell_cycle, cell_signaling	0.0110757	1.299
72	spryPathway_h	BioCarta	H003178_01	Info	Mitogen-activated protein kinase 3	H003178_01	X60188	861	MAPK3	Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...	0.0986041	1.184
73	spryPathway_h	BioCarta	H001600_01	Info	RAS p21 protein activator (GTPase activating protein) 1	H001600_01	M23379	758	RASA1	EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction	0.1015906	0.844
74	spryPathway_h	BioCarta	H002722_01	Info	Mitogen-activated protein kinase kinase 1	H002722_01	L11284	3446	MAP2K1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...	0.7377933	0.973
75	MAPK_Cascade_h	GO	H003200_01	Info	Mitogen-activated protein kinase kinase 3	H003200_01	D87116	180533	MAP2K3	fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway	0.0009666	1.561
76	MAPK_Cascade_h	GO	H001648_01	Info	Myelin basic protein	H001648_01	M13577	69547	MBP		0.0014651	0.667
77	MAPK_Cascade_h	GO	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
78	MAPK_Cascade_h	GO	H002895_01	Info	Mitogen-activated protein kinase 14	H002895_01	L35263	79107	MAPK14	BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAPKinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm ...	0.0086925	1.429
79	MAPK_Cascade_h	GO	H003611_01	Info	Mitogen-activated protein kinase kinase 4	H003611_01	L36870	75217	MAP2K4	Perou's- Intrinsic- Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system	0.012502	0.753
80	MAPK_Cascade_h	GO	H003178_01	Info	Mitogen-activated protein kinase 3	H003178_01	X60188	861	MAPK3	Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...	0.0986041	1.184
81	MAPK_Cascade_h	GO	H000029_01	Info	Mitogen-activated protein kinase kinase kinase 3	H000029_01	U78876	29282	MAP3K3	MAPKinase Signaling Pathway, Phosphatidylinositol signaling system	0.2027051	1.138
82	MAPK_Cascade_h	GO	H002943_01	Info	V-raf murine sarcoma viral oncogene homolog B1	H002943_01	M95712	622	BRAF	MAPKinase Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction, tsonc	0.2376595	0.895
83	MAPK_Cascade_h	GO	H003309_01	Info	Mitogen-activated protein kinase kinase 7	H003309_01	AF013589	110299	MAP2K7	Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAPKinase Signaling Pathway	0.3044184	1.088
84	MAPK_Cascade_h	GO	H002722_01	Info	Mitogen-activated protein kinase kinase 1	H002722_01	L11284	3446	MAP2K1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...	0.7377933	0.973
85	radiation_sensitivity_h	BioCarta	H001935_01	Info	Glyceraldehyde-3-phosphate dehydrogenase	H001935_01	U34995	169476	GAPD		0.0001082	1.485
86	radiation_sensitivity_h	BioCarta	H002040_01	Info	Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)	H002040_01	X00588	77432	EGFR	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degredation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc	0.0004362	0.669
87	radiation_sensitivity_h	BioCarta	H003112_01	Info	Retinoblastoma 1 (including osteosarcoma)	H003112_01	L41870	75770	RB1	BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc	0.0008596	0.674
88	radiation_sensitivity_h	BioCarta	H002681_01	Info	Cyclin D3	H002681_01	M92287	83173	CCND3	Cyclins and Cell Cycle Regulation, cell_cycle	0.0084801	1.28
89	radiation_sensitivity_h	BioCarta	H002092_01	Info	Ataxia telangiectasia and Rad3 related	H002092_01	U49844	77613	ATR	Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Regulation of cell cycle progression by Plk3, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Phosphatidylinositol signaling system, DNA_replication, immunology	0.0105491	0.753
90	radiation_sensitivity_h	BioCarta	H003739_01	Info	Cell division cycle 2, G1 to S and G2 to M	H003739_01	X05360	184572	CDC2	Activation of Src by Protein-tyrosine phosphatase alpha, AKAP95 role in mitosis and chromosome dynamics, cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, How Progesterone Initiates the Oocyte Maturation, Protein Kinase A at the Centrosome, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of Splicing through Sam68, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, Stathmin and breast cancer resistance to antimicrotubule agents, Phosphatidylinositol signaling system, cell_cycle	0.0222229	0.733
91	radiation_sensitivity_h	BioCarta	H002789_01	Info	Tumor protein p53 (Li-Fraumeni syndrome)	H002789_01	NM_000546	1846	TP53	Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc	0.0273242	1.207
92	radiation_sensitivity_h	BioCarta	H002149_01	Info	Cyclin-dependent kinase inhibitor 1A (p21, Cip1)	H002149_01	U03106	179665	CDKN1A	ATM Signaling Pathway, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, Effects of calcineurin in Keratinocyte Differentiation, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia and p53 in the Cardiovascular system, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, immunology, tsonc	0.0349766	1.236
93	radiation_sensitivity_h	BioCarta	H002473_01	Info	Insulin-like growth factor 1 receptor	H002473_01	NM_000875	239176	IGF1R	Perou's- Intrinsic- Breast-Cancer-Genes, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Erk1/Erk2 Mapk Signaling pathway, IGF-1 Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Telomeres, Telomerase, Cellular Aging, and Immortality, The IGF-1 Receptor and Longevity, immunology	0.079692	1.158
94	radiation_sensitivity_h	BioCarta	H002987_01	Info	Cyclin B2	H002987_01	AK001404	194698	CCNB2	Estrogen-responsive protein Efp controls cell cycle and breast tumors growth	0.0829851	0.84
95	radiation_sensitivity_h	BioCarta	H002323_01	Info	Cyclin E1	H002323_01	M74093	9700	CCNE1	Perou's- Intrinsic- Breast-Cancer-Genes, CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression, cell_cycle	0.1107382	0.884
96	radiation_sensitivity_h	BioCarta	H002760_01	Info	RAD51 (S. cerevisiae) homolog (E coli RecA homolog)	H002760_01	D14134	23044	RAD51	ATM Signaling Pathway, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, DNA_damage, DNA_replication	0.1212274	1.154
97	radiation_sensitivity_h	BioCarta	H003605_01	Info	BCL2-associated X protein	H003605_01	L22474	159428	BAX	Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology	0.253339	0.907
98	radiation_sensitivity_h	BioCarta	H003644_01	Info	Tumor necrosis factor receptor superfamily, member 6	H003644_01	X63717	82359	TNFRSF6	apoptosis, immunology	0.4621499	0.927
99	radiation_sensitivity_h	BioCarta	H003538_01	Info	Actin, beta	H003538_01	NM_001101	288061	ACTB	Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes	0.6253266	0.956
100	radiation_sensitivity_h	BioCarta	H003542_01	Info	V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene	H003542_01	M11730	323910	ERBB2	Perou's- Intrinsic- Breast-Cancer-Genes, Role of ERBB2 in Signal Transduction and Oncology, Trefoil Factors Initiate Mucosal Healing, immunology, signal_transduction, tsonc	0.7160857	1.031
101	radiation_sensitivity_h	BioCarta	H006841_01	Info	Homo sapiens mRNA; cDNA DKFZp564P073 (from clone DKFZp564P073)	H006841_01	AL049301	278577		Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology	0.7810094	0.98
102	radiation_sensitivity_h	BioCarta	H003766_01	Info	Mouse double minute 2, human homolog of; p53-binding protein	H003766_01	M92424	170027	MDM2	ATM Signaling Pathway, Cell Cycle: G2/M Checkpoint, CTCF: First Multivalent Nuclear Factor, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Sumoylation by RanBP2 Regulates Transcriptional Repression, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, gene_regulation, transcription, tsonc	0.8018001	0.978
103	radiation_sensitivity_h	BioCarta	H003816_01	Info	Caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase)	H003816_01	M87507	2490	CASP1	Caspase Cascade in Apoptosis, D4-GDI Signaling Pathway, IL 18 Signaling Pathway, apoptosis, immunology	0.9157209	1.011
104	radiation_sensitivity_h	BioCarta	H003027_01	Info	Cyclin D2	H003027_01	D13639	75586	CCND2	Cyclins and Cell Cycle Regulation, cell_cycle	0.9682473	0.996
105	insulinPathway_h	BioCarta	H000732_01	Info	Insulin receptor substrate 1	H000732_01	S62539	96063	IRS1	Perou's- Intrinsic- Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology	0.0013348	0.643
106	insulinPathway_h	BioCarta	H002186_01	Info	Serum response factor (c-fos serum response element-binding transcription factor)	H002186_01	J03161	155321	SRF	EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription	0.0017465	0.722
107	insulinPathway_h	BioCarta	H002055_01	Info	Growth factor receptor-bound protein 2	H002055_01	M96995	296381	GRB2	Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...	0.0022348	1.459
108	insulinPathway_h	BioCarta	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
109	insulinPathway_h	BioCarta	H003178_01	Info	Mitogen-activated protein kinase 3	H003178_01	X60188	861	MAPK3	Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...	0.0986041	1.184
110	insulinPathway_h	BioCarta	H001600_01	Info	RAS p21 protein activator (GTPase activating protein) 1	H001600_01	M23379	758	RASA1	EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction	0.1015906	0.844
111	insulinPathway_h	BioCarta	H003158_01	Info	Mitogen-activated protein kinase 8	H003158_01	L26318	190913	MAPK8	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...	0.1287835	1.166
112	insulinPathway_h	BioCarta	H002624_01	Info	Insulin receptor	H002624_01	X02160	89695	INSR	Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Growth Hormone Signaling Pathway, Insulin Signaling Pathway, immunology	0.433218	0.919
113	insulinPathway_h	BioCarta	H002722_01	Info	Mitogen-activated protein kinase kinase 1	H002722_01	L11284	3446	MAP2K1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...	0.7377933	0.973
114	cellcyclePathway_h	Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.	H003112_01	Info	Retinoblastoma 1 (including osteosarcoma)	H003112_01	L41870	75770	RB1	BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc	0.0008596	0.674
115	cellcyclePathway_h	Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.	H002412_01	Info	Cyclin-dependent kinase 2	H002412_01	M68520	19192	CDK2	CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, immunology, signal_transduction	0.0040171	0.711
116	cellcyclePathway_h	Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.	H002681_01	Info	Cyclin D3	H002681_01	M92287	83173	CCND3	Cyclins and Cell Cycle Regulation, cell_cycle	0.0084801	1.28
117	cellcyclePathway_h	Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.	H000136_01	Info	Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	H000136_01	AF041248	4854	CDKN2C	Cyclins and Cell Cycle Regulation, immunology	0.0088074	0.705
118	cellcyclePathway_h	Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.	H005436_01	Info	Homo sapiens cDNA FLJ20653 fis, clone KAT01739	H005436_01	AK000660	180059		Perou's- Intrinsic- Breast-Cancer-Genes, Cell Cycle: G1/S Check Point , Cyclins and Cell Cycle Regulation, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Influence of Ras and Rho proteins on G1 to S Transition, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction	0.0126769	0.793
119	cellcyclePathway_h	Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.	H003739_01	Info	Cell division cycle 2, G1 to S and G2 to M	H003739_01	X05360	184572	CDC2	Activation of Src by Protein-tyrosine phosphatase alpha, AKAP95 role in mitosis and chromosome dynamics, cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, How Progesterone Initiates the Oocyte Maturation, Protein Kinase A at the Centrosome, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of Splicing through Sam68, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, Stathmin and breast cancer resistance to antimicrotubule agents, Phosphatidylinositol signaling system, cell_cycle	0.0222229	0.733
120	cellcyclePathway_h	Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.	H003410_01	Info	Cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	H003410_01	U26727	1174	CDKN2A	Cell Cycle: G1/S Check Point , CTCF: First Multivalent Nuclear Factor, Cyclins and Cell Cycle Regulation, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc	0.0245577	0.782
121	cellcyclePathway_h	Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.	H003759_01	Info	Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	H003759_01	U40343	29656	CDKN2D	Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation	0.0311312	1.253
122	cellcyclePathway_h	Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.	H002149_01	Info	Cyclin-dependent kinase inhibitor 1A (p21, Cip1)	H002149_01	U03106	179665	CDKN1A	ATM Signaling Pathway, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, Effects of calcineurin in Keratinocyte Differentiation, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia and p53 in the Cardiovascular system, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, immunology, tsonc	0.0349766	1.236
123	cellcyclePathway_h	Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.	H002371_01	Info	Cyclin B1	H002371_01	M25753	23960	CCNB1	Activation of Src by Protein-tyrosine phosphatase alpha, AKAP95 role in mitosis and chromosome dynamics, Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, How Progesterone Initiates the Oocyte Maturation, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, Stathmin and breast cancer resistance to antimicrotubule agents, cell_cycle	0.037756	0.797
124	cellcyclePathway_h	Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.	H002323_01	Info	Cyclin E1	H002323_01	M74093	9700	CCNE1	Perou's- Intrinsic- Breast-Cancer-Genes, CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression, cell_cycle	0.1107382	0.884
125	cellcyclePathway_h	Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.	H001999_01	Info	Cyclin D1 (PRAD1: parathyroid adenomatosis 1)	H001999_01	X59798	82932	CCND1	Perou's- Intrinsic- Breast-Cancer-Genes, BTG family proteins and cell cycle regulation, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G1/S Check Point , Cyclins and Cell Cycle Regulation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, WNT Signaling Pathway, cell_cycle, tsonc	0.3215316	0.898
126	cellcyclePathway_h	Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.	H003750_01	Info	Cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	H003750_01	AF004819	72901	CDKN2B	Cell Cycle: G1/S Check Point , Cyclins and Cell Cycle Regulation, cell_cycle, cell_signaling, signal_transduction, tsonc	0.3235256	0.886
127	cellcyclePathway_h	Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.	H000126_01	Info	Retinoblastoma-like 1 (p107)	H000126_01	L14812	87	RBL1	Cyclins and Cell Cycle Regulation, METS affect on Macrophage Differentiation, cell_cycle	0.4736162	1.053
128	cellcyclePathway_h	Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.	H003162_01	Info	Transcription factor Dp-1	H003162_01	L23959	279576	TFDP1	Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, Regulation of p27 Phosphorylation during Cell Cycle Progression	0.6646128	0.958
129	cellcyclePathway_h	Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.	H002606_01	Info	Cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase)	H002606_01	L20320	184298	CDK7	Perou's- Intrinsic- Breast-Cancer-Genes, Cyclins and Cell Cycle Regulation, Degradation of the RAR and RXR by the proteasome, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction	0.9364784	0.991
130	cellcyclePathway_h	Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.	H003027_01	Info	Cyclin D2	H003027_01	D13639	75586	CCND2	Cyclins and Cell Cycle Regulation, cell_cycle	0.9682473	0.996
131	HOXA9_DOWN_h	Dorsam_et_al_2004	H003124_01	Info	Fc fragment of IgG, receptor, transporter, alpha	H003124_01	U12255	111903	FCGRT		2.86e-05	1.917
132	HOXA9_DOWN_h	Dorsam_et_al_2004	H000825_01	Info	S100 calcium-binding protein A8 (calgranulin A)	H000825_01	X06234	100000	S100A8	immunology	0.0001788	2.746
133	HOXA9_DOWN_h	Dorsam_et_al_2004	H002406_01	Info	Jun B proto-oncogene	H002406_01	X51345	198951	JUNB	GATA3 participate in activating the Th2 cytokine genes expression, tsonc	0.0021761	1.408
134	HOXA9_DOWN_h	Dorsam_et_al_2004	H002878_01	Info	V-yes-1 Yamaguchi sarcoma viral related oncogene homolog	H002878_01	M16038	80887	LYN	BCR Signaling Pathway, Eph Kinases and ephrins support platelet aggregation, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., immunology, signal_transduction, tsonc	0.0068841	1.545
135	HOXA9_DOWN_h	Dorsam_et_al_2004	H000316_01	Info	Delta sleep inducing peptide, immunoreactor	H000316_01	AL110191	75450	DSIPI		0.0102545	1.531
136	HOXA9_DOWN_h	Dorsam_et_al_2004	H006355_01	Info	KIAA1451 protein	H006355_01	AL049923	109694	KIAA1451		0.0105169	1.369
137	HOXA9_DOWN_h	Dorsam_et_al_2004	H000199_01	Info	Translocated promoter region (to activated MET oncogene)	H000199_01	X66397	169750	TPR	tsonc	0.036441	0.801
138	HOXA9_DOWN_h	Dorsam_et_al_2004	H001971_01	Info	Retinoblastoma-binding protein 6	H001971_01	X85133	85273	RBBP6		0.0366619	0.747
139	HOXA9_DOWN_h	Dorsam_et_al_2004	H006255_01	Info	Syndecan binding protein (syntenin)	H006255_01	AF000652	8180	SDCBP		0.0567867	1.234
140	HOXA9_DOWN_h	Dorsam_et_al_2004	H002168_01	Info	GATA-binding protein 2	H002168_01	M68891	760	GATA2	gene_regulation, misc, transcription	0.0841754	0.806
141	HOXA9_DOWN_h	Dorsam_et_al_2004	H004936_01	Info	DKFZP564A122 protein	H004936_01	AL110269	187991	DKFZP564A122		0.0852946	1.175
142	HOXA9_DOWN_h	Dorsam_et_al_2004	H007504_01	Info	Hemoglobin, epsilon 1	H007504_01	NM_005330	117848	HBE1		0.118007	0.749
143	HOXA9_DOWN_h	Dorsam_et_al_2004	H002091_01	Info	V-myc avian myelocytomatosis viral oncogene homolog	H002091_01	K02276	79070	MYC	Cadmium induces DNA synthesis and proliferation in macrophages, CTCF: First Multivalent Nuclear Factor, Erk1/Erk2 Mapk Signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, MAPKinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, WNT Signaling Pathway, gene_regulation, immunology, transcription, tsonc	0.1797519	0.824
144	HOXA9_DOWN_h	Dorsam_et_al_2004	H001023_01	Info	Mannosidase, alpha, class 2A, member 2	H001023_01	L28821	295605	MAN2A2	ER�associated degradation (ERAD) Pathway, Steps in the Glycosylation of Mammalian N-linked Oligosaccarides, N-Glycan biosynthesis	0.2111813	1.139
145	HOXA9_DOWN_h	Dorsam_et_al_2004	H003255_01	Info	CDC37 (cell division cycle 37, S. cerevisiae, homolog)	H003255_01	U43077	160958	CDC37		0.2178008	0.878
146	HOXA9_DOWN_h	Dorsam_et_al_2004	H000068_01	Info	Signal recognition particle 72kD	H000068_01	AF069765	237825	SRP72	Perou's- Intrinsic- Breast-Cancer-Genes	0.2609516	0.897
147	HOXA9_DOWN_h	Dorsam_et_al_2004	H012741_01	Info	Glutaredoxin (thioltransferase)	H012741_01	AF069668	28988	GLRX	pharmacology	0.2704585	1.145
148	HOXA9_DOWN_h	Dorsam_et_al_2004	H006807_01	Info	Cytokine inducible SH2-containing protein	H006807_01	AF132297	8257	CISH	Growth Hormone Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, immunology	0.3746206	0.888
149	HOXA9_DOWN_h	Dorsam_et_al_2004	H004864_01	Info	Ubiquitin specific protease 1	H004864_01	AF117386	35086	USP1		0.3871195	0.908
150	HOXA9_DOWN_h	Dorsam_et_al_2004	H006584_01	Info	Splicing factor, arginine/serine-rich 11	H006584_01	M74002	11482	SFRS11		0.4576641	1.062
151	HOXA9_DOWN_h	Dorsam_et_al_2004	H010826_01	Info	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	H010826_01	AB024334	25001	YWHAG		0.6175419	1.047
152	HOXA9_DOWN_h	Dorsam_et_al_2004	H016588_01	Info	Hypothetical protein DKFZp761B2423	H016588_01	AK026954	91065	DKFZp761B2423		0.6339659	1.046
153	HOXA9_DOWN_h	Dorsam_et_al_2004	H010792_01	Info	Dynein, cytoplasmic, light intermediate polypeptide 2	H010792_01	AF035812	194625	DNCLI2		0.6511108	1.058
154	HOXA9_DOWN_h	Dorsam_et_al_2004	H002850_01	Info	Murine leukemia viral (bmi-1) oncogene homolog	H002850_01	L13689	431	BMI1	Perou's- Intrinsic- Breast-Cancer-Genes, The PRC2 Complex Sets Long-term Gene Silencing Through Modification of Histone Tails, immunology, tsonc	0.7846354	0.976
155	HOXA9_DOWN_h	Dorsam_et_al_2004	H003618_01	Info	Dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)	H003618_01	D17547	301865	DCT	Tyrosine metabolism	0.9648525	0.996
156	gata3Pathway_h	BioCarta	H003200_01	Info	Mitogen-activated protein kinase kinase 3	H003200_01	D87116	180533	MAP2K3	fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway	0.0009666	1.561
157	gata3Pathway_h	BioCarta	H002406_01	Info	Jun B proto-oncogene	H002406_01	X51345	198951	JUNB	GATA3 participate in activating the Th2 cytokine genes expression, tsonc	0.0021761	1.408
158	gata3Pathway_h	BioCarta	H003415_01	Info	Protein kinase, cAMP-dependent, catalytic, beta	H003415_01	M34181	87773	PRKACB	Perou's- Intrinsic- Breast-Cancer-Genes, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction	0.0048904	0.647
159	gata3Pathway_h	BioCarta	H002895_01	Info	Mitogen-activated protein kinase 14	H002895_01	L35263	79107	MAPK14	BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAPKinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm ...	0.0086925	1.429
160	gata3Pathway_h	BioCarta	H006601_01	Info	V-maf musculoaponeurotic fibrosarcoma (avian) oncogene homolog	H006601_01	AF055376	30250	MAF	GATA3 participate in activating the Th2 cytokine genes expression, tsonc	0.079493	0.812
161	gata3Pathway_h	BioCarta	H001698_01	Info	Protein kinase, cAMP-dependent, regulatory, type II, alpha	H001698_01	X14968	289075	PRKAR2A	AKAP95 role in mitosis and chromosome dynamics, Protein Kinase A at the Centrosome, Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation	0.2569617	1.125
162	gata3Pathway_h	BioCarta	H000645_01	Info	Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	H000645_01	M33336	183037	PRKAR1A	Activation of cAMP-dependent protein kinase, PKA, cell_cycle, cell_signaling, signal_transduction	0.4305614	0.935
163	gata3Pathway_h	BioCarta	H002045_01	Info	Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	H002045_01	U80917	96149	NFATC1	BCR Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Effects of calcineurin in Keratinocyte Differentiation, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Role of MEF2D in T-cell Apoptosis, Signaling Pathway from G-Protein Families, T Cell Receptor Signaling Pathway, immunology	0.623508	1.051
164	ctla4Pathway_h	T cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APCs CD80 or 86.	H001032_01	Info	Cytotoxic T-lymphocyte-associated protein 4	H001032_01	L15006	247824	CTLA4	The Co-Stimulatory Signal During T-cell Activation, immunology	0.0001134	0.56
165	ctla4Pathway_h	T cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APCs CD80 or 86.	H002055_01	Info	Growth factor receptor-bound protein 2	H002055_01	M96995	296381	GRB2	Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...	0.0022348	1.459
166	ctla4Pathway_h	T cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APCs CD80 or 86.	H001210_01	Info	Major histocompatibility complex, class II, DR beta 3	H001210_01	V00522	279930	HLA-DRB3	Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, Antigen Dependent B Cell Activation, Antigen Processing and Presentation, B Lymphocyte Cell Surface Molecules, Bystander B Cell Activation, Cytokines and Inflammatory Response, IL 5 Signaling Pathway, Lck and Fyn tyrosine kinases in initiation of TCR Activation, Th1/Th2 Differentiation, The Co-Stimulatory Signal During T-cell Activation, The Role of Eosinophils in the Chemokine Network of Allergy, immunology	0.0031398	1.8
167	ctla4Pathway_h	T cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APCs CD80 or 86.	H003054_01	Info	Major histocompatibility complex, class II, DR alpha	H003054_01	J00194	76807	HLA-DRA	Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, Antigen Dependent B Cell Activation, Antigen Processing and Presentation, B Lymphocyte Cell Surface Molecules, Bystander B Cell Activation, Cytokines and Inflammatory Response, IL 5 Signaling Pathway, Lck and Fyn tyrosine kinases in initiation of TCR Activation, Th1/Th2 Differentiation, The Co-Stimulatory Signal During T-cell Activation, The Role of Eosinophils in the Chemokine Network of Allergy, immunology	0.0045394	1.755
168	ctla4Pathway_h	T cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APCs CD80 or 86.	H002284_01	Info	Major histocompatibility complex, class II, DR beta 5	H002284_01	M20430	308026	HLA-DRB5	Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, Antigen Dependent B Cell Activation, Antigen Processing and Presentation, B Lymphocyte Cell Surface Molecules, Bystander B Cell Activation, Cytokines and Inflammatory Response, IL 5 Signaling Pathway, Lck and Fyn tyrosine kinases in initiation of TCR Activation, Th1/Th2 Differentiation, The Co-Stimulatory Signal During T-cell Activation, The Role of Eosinophils in the Chemokine Network of Allergy, immunology	0.0670054	1.503
169	ctla4Pathway_h	T cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APCs CD80 or 86.	H015660_01	Info	Major histocompatibility complex, class II, DR beta 4	H015660_01	NM_021983	293934	HLA-DRB4	Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, Antigen Dependent B Cell Activation, Antigen Processing and Presentation, B Lymphocyte Cell Surface Molecules, Bystander B Cell Activation, Cytokines and Inflammatory Response, IL 5 Signaling Pathway, Lck and Fyn tyrosine kinases in initiation of TCR Activation, Th1/Th2 Differentiation, The Co-Stimulatory Signal During T-cell Activation, The Role of Eosinophils in the Chemokine Network of Allergy, immunology	0.2187912	0.885
170	ctla4Pathway_h	T cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APCs CD80 or 86.	H003820_01	Info	Lymphocyte-specific protein tyrosine kinase	H003820_01	X05027	1765	LCK	Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, IL 2 signaling pathway, IL-7 Signal Transduction, Lck and Fyn tyrosine kinases in initiation of TCR Activation, T Cell Receptor Signaling Pathway, The Co-Stimulatory Signal During T-cell Activation, immunology, signal_transduction, tsonc	0.2266863	0.873
171	ctla4Pathway_h	T cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APCs CD80 or 86.	H000858_01	Info	Homo sapiens, clone MGC:12387, mRNA, complete cds	H000858_01	M16942	318720		Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, Antigen Dependent B Cell Activation, Antigen Processing and Presentation, B Lymphocyte Cell Surface Molecules, Bystander B Cell Activation, Cytokines and Inflammatory Response, IL 5 Signaling Pathway, Lck and Fyn tyrosine kinases in initiation of TCR Activation, Th1/Th2 Differentiation, The Co-Stimulatory Signal During T-cell Activation, The Role of Eosinophils in the Chemokine Network of Allergy, immunology	0.2327988	1.274
172	ctla4Pathway_h	T cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APCs CD80 or 86.	H001197_01	Info	T cell receptor beta locus	H001197_01	X00437	303157	TRB@		0.4180662	0.913
173	ctla4Pathway_h	T cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APCs CD80 or 86.	H002570_01	Info	Interleukin 2	H002570_01	S82692	89679	IL2	Antigen Dependent B Cell Activation, Cytokine Network, Cytokines and Inflammatory Response, IL 18 Signaling Pathway, IL 2 signaling pathway, OX40 Signaling Pathway, Regulation of hematopoiesis by cytokines, Role of Tob in T-cell activation, Selective expression of chemokine receptors during T-cell polarization, Th1/Th2 Differentiation, The 4-1BB-dependent immune response, The Co-Stimulatory Signal During T-cell Activation, immunology	0.6483346	1.043
174	ctla4Pathway_h	T cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APCs CD80 or 86.	H001267_01	Info	CD3Z antigen, zeta polypeptide (TiT3 complex)	H001267_01	NM_000734	97087	CD3Z	immunology	0.8300402	1.024
175	cell_cycle_checkpointII_h	GO	H003112_01	Info	Retinoblastoma 1 (including osteosarcoma)	H003112_01	L41870	75770	RB1	BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc	0.0008596	0.674
176	cell_cycle_checkpointII_h	GO	H001983_01	Info	Fanconi anemia, complementation group G	H001983_01	AJ007669	8047	FANCG	BRCA1-dependent Ub-ligase activity, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, DNA_damage, immunology	0.0098981	0.692
177	cell_cycle_checkpointII_h	GO	H002092_01	Info	Ataxia telangiectasia and Rad3 related	H002092_01	U49844	77613	ATR	Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Regulation of cell cycle progression by Plk3, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Phosphatidylinositol signaling system, DNA_replication, immunology	0.0105491	0.753
178	cell_cycle_checkpointII_h	GO	H003410_01	Info	Cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	H003410_01	U26727	1174	CDKN2A	Cell Cycle: G1/S Check Point , CTCF: First Multivalent Nuclear Factor, Cyclins and Cell Cycle Regulation, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc	0.0245577	0.782
179	cell_cycle_checkpointII_h	GO	H002789_01	Info	Tumor protein p53 (Li-Fraumeni syndrome)	H002789_01	NM_000546	1846	TP53	Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc	0.0273242	1.207
180	cell_cycle_checkpointII_h	GO	H001967_01	Info	Cyclin E2	H001967_01	AF091433	30464	CCNE2	cell_cycle	0.0814824	0.826
181	cell_cycle_checkpointII_h	GO	H002232_01	Info	Cell division cycle 34	H002232_01	L22005	76932	CDC34	Cell Cycle: G2/M Checkpoint, Cyclin E Destruction Pathway, E2F1 Destruction Pathway, Ubiquitin mediated proteolysis	0.8799021	0.983
182	g1Pathway_h	BioCarta	H003112_01	Info	Retinoblastoma 1 (including osteosarcoma)	H003112_01	L41870	75770	RB1	BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc	0.0008596	0.674
183	g1Pathway_h	BioCarta	H002412_01	Info	Cyclin-dependent kinase 2	H002412_01	M68520	19192	CDK2	CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, immunology, signal_transduction	0.0040171	0.711
184	g1Pathway_h	BioCarta	H002092_01	Info	Ataxia telangiectasia and Rad3 related	H002092_01	U49844	77613	ATR	Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Regulation of cell cycle progression by Plk3, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Phosphatidylinositol signaling system, DNA_replication, immunology	0.0105491	0.753
185	g1Pathway_h	BioCarta	H005436_01	Info	Homo sapiens cDNA FLJ20653 fis, clone KAT01739	H005436_01	AK000660	180059		Perou's- Intrinsic- Breast-Cancer-Genes, Cell Cycle: G1/S Check Point , Cyclins and Cell Cycle Regulation, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Influence of Ras and Rho proteins on G1 to S Transition, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction	0.0126769	0.793
186	g1Pathway_h	BioCarta	H003739_01	Info	Cell division cycle 2, G1 to S and G2 to M	H003739_01	X05360	184572	CDC2	Activation of Src by Protein-tyrosine phosphatase alpha, AKAP95 role in mitosis and chromosome dynamics, cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, How Progesterone Initiates the Oocyte Maturation, Protein Kinase A at the Centrosome, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of Splicing through Sam68, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, Stathmin and breast cancer resistance to antimicrotubule agents, Phosphatidylinositol signaling system, cell_cycle	0.0222229	0.733
187	g1Pathway_h	BioCarta	H003410_01	Info	Cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	H003410_01	U26727	1174	CDKN2A	Cell Cycle: G1/S Check Point , CTCF: First Multivalent Nuclear Factor, Cyclins and Cell Cycle Regulation, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc	0.0245577	0.782
188	g1Pathway_h	BioCarta	H002789_01	Info	Tumor protein p53 (Li-Fraumeni syndrome)	H002789_01	NM_000546	1846	TP53	Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc	0.0273242	1.207
189	g1Pathway_h	BioCarta	H002149_01	Info	Cyclin-dependent kinase inhibitor 1A (p21, Cip1)	H002149_01	U03106	179665	CDKN1A	ATM Signaling Pathway, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, Effects of calcineurin in Keratinocyte Differentiation, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia and p53 in the Cardiovascular system, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, immunology, tsonc	0.0349766	1.236
190	g1Pathway_h	BioCarta	H002323_01	Info	Cyclin E1	H002323_01	M74093	9700	CCNE1	Perou's- Intrinsic- Breast-Cancer-Genes, CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression, cell_cycle	0.1107382	0.884
191	g1Pathway_h	BioCarta	H003207_01	Info	V-abl Abelson murine leukemia viral oncogene homolog 1	H003207_01	NM_005157	146355	ABL1	cell_signaling, signal_transduction, tsonc	0.1292454	0.826
192	g1Pathway_h	BioCarta	H003023_01	Info	Dihydrofolate reductase	H003023_01	NM_000791	83765	DHFR	Cell Cycle: G1/S Check Point , Folate biosynthesis, One carbon pool by folate, immunology, pharmacology	0.1336155	0.862
193	g1Pathway_h	BioCarta	H001999_01	Info	Cyclin D1 (PRAD1: parathyroid adenomatosis 1)	H001999_01	X59798	82932	CCND1	Perou's- Intrinsic- Breast-Cancer-Genes, BTG family proteins and cell cycle regulation, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G1/S Check Point , Cyclins and Cell Cycle Regulation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, WNT Signaling Pathway, cell_cycle, tsonc	0.3215316	0.898
194	g1Pathway_h	BioCarta	H003750_01	Info	Cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	H003750_01	AF004819	72901	CDKN2B	Cell Cycle: G1/S Check Point , Cyclins and Cell Cycle Regulation, cell_cycle, cell_signaling, signal_transduction, tsonc	0.3235256	0.886
195	g1Pathway_h	BioCarta	H009086_01	Info	S-phase kinase-associated protein 2 (p45)	H009086_01	U33761	23348	SKP2	Cell Cycle: G1/S Check Point , E2F1 Destruction Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression	0.330649	1.089
196	g1Pathway_h	BioCarta	H000650_01	Info	Glycogen synthase kinase 3 beta	H000650_01	L33801	78802	GSK3B	ALK in cardiac myocytes, Cell Cycle: G1/S Check Point , Deregulation of CDK5 in Alzheimers Disease, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Presenilin action in Notch and Wnt signaling, Regulation of eIF2, Segmentation Clock, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Sonic Hedgehog (Shh) Pathway, WNT Signaling Pathway, Phosphatidylinositol signaling system	0.353328	1.118
197	g1Pathway_h	BioCarta	H003162_01	Info	Transcription factor Dp-1	H003162_01	L23959	279576	TFDP1	Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, Regulation of p27 Phosphorylation during Cell Cycle Progression	0.6646128	0.958
198	g1Pathway_h	BioCarta	H000578_01	Info	Histone deacetylase 1	H000578_01	D50405	88556	HDAC1	immunology	0.8155423	1.017
199	EMT_UP_h	Jechlinger_et_al_2003	H003225_01	Info	Interferon regulatory factor 7	H003225_01	AF076494	166120	IRF7	gene_regulation, transcription	6.44e-05	1.728
200	EMT_UP_h	Jechlinger_et_al_2003	H000825_01	Info	S100 calcium-binding protein A8 (calgranulin A)	H000825_01	X06234	100000	S100A8	immunology	0.0001788	2.746
201	EMT_UP_h	Jechlinger_et_al_2003	H001850_01	Info	Interferon-stimulated protein, 15 kDa	H001850_01	M13755	833	ISG15		0.0003862	1.943
202	EMT_UP_h	Jechlinger_et_al_2003	H000473_01	Info	Uridine phosphorylase	H000473_01	X90858	77573	UP	Pyrimidine metabolism	0.0005102	1.339
203	EMT_UP_h	Jechlinger_et_al_2003	H002726_01	Info	B-cell CLL/lymphoma 3	H002726_01	M31732	31210	BCL3	tsonc	0.0147426	1.351
204	EMT_UP_h	Jechlinger_et_al_2003	H003466_01	Info	CD68 antigen	H003466_01	S57235	246381	CD68	angiogenesis, immunology, metastasis	0.0179458	1.335
205	EMT_UP_h	Jechlinger_et_al_2003	H003299_01	Info	Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	H003299_01	M59979	88474	PTGS1	Aspirin Blocks Signaling Pathway Involved in Platelet Activation, Eicosanoid Metabolism, Mechanism of Acetaminophen Activity and Toxicity, Prostaglandin and leukotriene metabolism, immunology	0.023304	0.813
206	EMT_UP_h	Jechlinger_et_al_2003	H003029_01	Info	Disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein)	H003029_01	U53446	81988	DAB2		0.0291633	0.78
207	EMT_UP_h	Jechlinger_et_al_2003	H003752_01	Info	Platelet-derived growth factor receptor, beta polypeptide	H003752_01	J03278	76144	PDGFRB	cell_cycle, cell_signaling, immunology, misc, signal_transduction	0.0333891	0.832
208	EMT_UP_h	Jechlinger_et_al_2003	H006885_01	Info	Ribonuclease 6 precursor	H006885_01	NM_003730	8297	RNASE6PL		0.0955467	1.208
209	EMT_UP_h	Jechlinger_et_al_2003	H000998_01	Info	Solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	H000998_01	AB018010	79748	SLC3A2	Perou's- Intrinsic- Breast-Cancer-Genes	0.1156436	0.843
210	EMT_UP_h	Jechlinger_et_al_2003	H001908_01	Info	Discoidin domain receptor family, member 2	H001908_01	X74764	71891	DDR2		0.1167676	0.839
211	EMT_UP_h	Jechlinger_et_al_2003	H001001_01	Info	Procollagen C-endopeptidase enhancer	H001001_01	NM_002593	202097	PCOLCE		0.1228497	0.868
212	EMT_UP_h	Jechlinger_et_al_2003	H000774_01	Info	Collagen, type VI, alpha 1	H000774_01	X15880	108885	COL6A1		0.1448402	0.841
213	EMT_UP_h	Jechlinger_et_al_2003	H002775_01	Info	Platelet-derived growth factor receptor, alpha polypeptide	H002775_01	M21574	74615	PDGFRA	Perou's- Intrinsic- Breast-Cancer-Genes, CBL mediated ligand-induced downregulation of EGF receptors, Erk1/Erk2 Mapk Signaling pathway, PDGF Signaling Pathway, Phospholipids as signalling intermediaries, Rac 1 cell motility signaling pathway, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, immunology, signal_transduction	0.1636921	1.107
214	EMT_UP_h	Jechlinger_et_al_2003	H010646_01	Info	Ribonuclease 6 precursor	H010646_01	AK001769	8297	RNASE6PL		0.1872503	1.127
215	EMT_UP_h	Jechlinger_et_al_2003	H002295_01	Info	Adenosine deaminase	H002295_01	X02994	1217	ADA	Purine metabolism, gene_regulation, immunology, transcription	0.1882263	0.871
216	EMT_UP_h	Jechlinger_et_al_2003	H012626_01	Info	Beta-2-microglobulin	H012626_01	AB021288	75415	B2M	Antigen Processing and Presentation, CTL mediated immune response against target cells , Ras-Independent pathway in NK cell-mediated cytotoxicity, immunology	0.1923361	1.156
217	EMT_UP_h	Jechlinger_et_al_2003	H003645_01	Info	Interleukin 11	H003645_01	X58377	1721	IL11	Cytokines and Inflammatory Response, Erythrocyte Differentiation Pathway, Regulation of hematopoiesis by cytokines, immunology	0.2074062	1.116
218	EMT_UP_h	Jechlinger_et_al_2003	H003593_01	Info	Collagen, type VI, alpha 2	H003593_01	AL096746	159263	COL6A2		0.300891	1.098
219	EMT_UP_h	Jechlinger_et_al_2003	H001198_01	Info	Homo sapiens, alpha-1 (VI) collagen	H001198_01	M20776	25459			0.3632512	1.1
220	EMT_UP_h	Jechlinger_et_al_2003	H002451_01	Info	Flavin containing monooxygenase 1	H002451_01	M64082	1424	FMO1	immunology, misc	0.3681883	0.911
221	EMT_UP_h	Jechlinger_et_al_2003	H000592_01	Info	Interferon-induced protein with tetratricopeptide repeats 1	H000592_01	X03557	20315	IFIT1		0.4335751	1.121
222	EMT_UP_h	Jechlinger_et_al_2003	H002713_01	Info	Phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	H002713_01	U24577	93304	PLA2G7	Glycerophospholipid metabolism	0.4631812	0.89
223	EMT_UP_h	Jechlinger_et_al_2003	H010497_01	Info	Interferon induced transmembrane protein 3 (1-8U)	H010497_01	X57352	182241	IFITM3		0.5875785	1.062
224	EMT_UP_h	Jechlinger_et_al_2003	H003695_01	Info	Secreted protein, acidic, cysteine-rich (osteonectin)	H003695_01	J03040	111779	SPARC	misc	0.6414286	1.051
225	EMT_UP_h	Jechlinger_et_al_2003	H002330_01	Info	Cadherin 15, M-cadherin (myotubule)	H002330_01	D83542	148090	CDH15		0.7996949	0.974
226	EMT_UP_h	Jechlinger_et_al_2003	H002397_01	Info	Methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase	H002397_01	X16396	154672	MTHFD2	Glyoxylate and dicarboxylate metabolism, One carbon pool by folate	0.8081788	0.975
227	EMT_UP_h	Jechlinger_et_al_2003	H002672_01	Info	G protein-coupled receptor	H002672_01	U67784	23016	RDC1		0.8527585	0.967
228	EMT_UP_h	Jechlinger_et_al_2003	H002490_01	Info	Hexabrachion (tenascin C, cytotactin)	H002490_01	X78565	289114	HXB	Perou's- Intrinsic- Breast-Cancer-Genes	0.856155	0.983
229	EMT_UP_h	Jechlinger_et_al_2003	H002283_01	Info	Secretory leukocyte protease inhibitor (antileukoproteinase)	H002283_01	X04470	251754	SLPI	Perou's- Intrinsic- Breast-Cancer-Genes, Proepithelin Conversion to Epithelin and Wound Repair Control, immunology	0.9075348	1.012
230	EMT_UP_h	Jechlinger_et_al_2003	H004245_01	Info	Snail 1 (drosophila homolog), zinc finger protein	H004245_01	AF125377	48029	SNAI1	Downregulated of MTA-3 in ER-negative Breast Tumors	0.9743253	1.003
231	tumor_supressor_h	BioCarta	H001935_01	Info	Glyceraldehyde-3-phosphate dehydrogenase	H001935_01	U34995	169476	GAPD		0.0001082	1.485
232	tumor_supressor_h	BioCarta	H003112_01	Info	Retinoblastoma 1 (including osteosarcoma)	H003112_01	L41870	75770	RB1	BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc	0.0008596	0.674
233	tumor_supressor_h	BioCarta	H002387_01	Info	MutS (E. coli) homolog 2 (colon cancer, nonpolyposis type 1)	H002387_01	NM_000251	78934	MSH2	DNA_damage, tsonc	0.004273	0.694
234	tumor_supressor_h	BioCarta	H000570_01	Info	CREB binding protein (Rubinstein-Taybi syndrome)	H000570_01	U47741	23598	CREBBP	gene_regulation, transcription	0.0048718	1.469
235	tumor_supressor_h	BioCarta	H000208_01	Info	Breast cancer 1, early onset	H000208_01	NM_007295	194143	BRCA1	ATM Signaling Pathway, BRCA1-dependent Ub-ligase activity, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, DNA_damage, immunology, tsonc	0.009032	0.746
236	tumor_supressor_h	BioCarta	H002789_01	Info	Tumor protein p53 (Li-Fraumeni syndrome)	H002789_01	NM_000546	1846	TP53	Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc	0.0273242	1.207
237	tumor_supressor_h	BioCarta	H003759_01	Info	Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	H003759_01	U40343	29656	CDKN2D	Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation	0.0311312	1.253
238	tumor_supressor_h	BioCarta	H002114_01	Info	Neurofibromin 2 (bilateral acoustic neuroma)	H002114_01	L11353	902	NF2	immunology, tsonc	0.2904249	0.837
239	tumor_supressor_h	BioCarta	H002700_01	Info	Transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kD)	H002700_01	L11695	220	TGFBR1	ALK in cardiac myocytes, Function of SLRP in Bone: An Integrated View, MAPKinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, p38 MAPK Signaling Pathway , TGF beta signaling pathway, Phosphatidylinositol signaling system, angiogenesis, development	0.3279632	0.903
240	tumor_supressor_h	BioCarta	H002611_01	Info	Interferon regulatory factor 1	H002611_01	X14454	80645	IRF1	gene_regulation, transcription	0.3284273	0.915
241	tumor_supressor_h	BioCarta	H006635_01	Info	Homo sapiens clone 23607 mRNA sequence	H006635_01	AF038181	167825		ALK in cardiac myocytes, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, Presenilin action in Notch and Wnt signaling, TGF beta signaling pathway, WNT Signaling Pathway, development, immunology, tsonc	0.6181322	1.041
242	tumor_supressor_h	BioCarta	H003538_01	Info	Actin, beta	H003538_01	NM_001101	288061	ACTB	Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes	0.6253266	0.956
243	tumor_supressor_h	BioCarta	H007492_01	Info	Cofilin 1 (non-muscle)	H007492_01	X95404	180370	CFL1	CCR3 signaling in Eosinophils, Rac 1 cell motility signaling pathway, Rho cell motility signaling pathway	0.685636	1.038
244	tumor_supressor_h	BioCarta	H003594_01	Info	Cyclin-dependent kinase inhibitor 1C (p57, Kip2)	H003594_01	U22398	106070	CDKN1C	cell_cycle, immunology, tsonc	0.7532847	0.968
245	tumor_supressor_h	BioCarta	H003151_01	Info	E1A binding protein p300	H003151_01	U01877	25272	EP300	Acetylation and Deacetylation of RelA in The Nucleus, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Control of Gene Expression by Vitamin D Receptor, Hypoxia and p53 in the Cardiovascular system, Hypoxia-Inducible Factor in the Cardiovascular System, IL-7 Signal Transduction, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Melanocyte Development and Pigmentation Pathway, Multi-step Regulation of Transcription by Pitx2, NFkB activation by Nontypeable Hemophilus influenzae, Pelp1 Modulation of Estrogen Receptor Activity, Role of ERBB2 in Signal Transduction and Oncology, Role of MEF2D in T-cell Apoptosis, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, TGF beta signaling pathway, Transcription Regulation by Methyltransferase of CARM1, gene_regulation, transcription	0.9607239	1.004
246	drug_resistance_and_metabolism_h	BioCarta	H001935_01	Info	Glyceraldehyde-3-phosphate dehydrogenase	H001935_01	U34995	169476	GAPD		0.0001082	1.485
247	drug_resistance_and_metabolism_h	BioCarta	H002040_01	Info	Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)	H002040_01	X00588	77432	EGFR	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degredation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc	0.0004362	0.669
248	drug_resistance_and_metabolism_h	BioCarta	H003596_01	Info	O-6-methylguanine-DNA methyltransferase	H003596_01	M29971	1384	MGMT	DNA_adducts, DNA_damage	0.0006291	0.667
249	drug_resistance_and_metabolism_h	BioCarta	H003112_01	Info	Retinoblastoma 1 (including osteosarcoma)	H003112_01	L41870	75770	RB1	BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc	0.0008596	0.674
250	drug_resistance_and_metabolism_h	BioCarta	H002412_01	Info	Cyclin-dependent kinase 2	H002412_01	M68520	19192	CDK2	CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, immunology, signal_transduction	0.0040171	0.711
251	drug_resistance_and_metabolism_h	BioCarta	H000872_01	Info	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	H000872_01	AF104942	108660	ABCC5		0.00423	0.773
252	drug_resistance_and_metabolism_h	BioCarta	H002387_01	Info	MutS (E. coli) homolog 2 (colon cancer, nonpolyposis type 1)	H002387_01	NM_000251	78934	MSH2	DNA_damage, tsonc	0.004273	0.694
253	drug_resistance_and_metabolism_h	BioCarta	H000208_01	Info	Breast cancer 1, early onset	H000208_01	NM_007295	194143	BRCA1	ATM Signaling Pathway, BRCA1-dependent Ub-ligase activity, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, DNA_damage, immunology, tsonc	0.009032	0.746
254	drug_resistance_and_metabolism_h	BioCarta	H003606_01	Info	Retinoid X receptor, alpha	H003606_01	U66306	20084	RXRA	Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Control of Gene Expression by Vitamin D Receptor, Degradation of the RAR and RXR by the proteasome, FXR and LXR Regulation of Cholesterol Metabolism, Map Kinase Inactivation of SMRT Corepressor, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, Transcription Regulation by Methyltransferase of CARM1, Visceral Fat Deposits and the Metabolic Syndrome, development, gene_regulation, transcription	0.0142664	1.308
255	drug_resistance_and_metabolism_h	BioCarta	H001848_01	Info	Glutathione S-transferase M1	H001848_01	J03817	324730	GSTM1	Glutathione metabolism, immunology, pharmacology	0.018415	0.773
256	drug_resistance_and_metabolism_h	BioCarta	H003283_01	Info	Topoisomerase (DNA) II alpha (170kD)	H003283_01	J04088	156346	TOP2A	Apoptotic DNA fragmentation and tissue homeostasis, DNA_adducts, DNA_damage, DNA_replication	0.0203748	0.733
257	drug_resistance_and_metabolism_h	BioCarta	H002533_01	Info	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	H002533_01	AF076622	274260	ABCC6		0.0229826	1.478
258	drug_resistance_and_metabolism_h	BioCarta	H003410_01	Info	Cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	H003410_01	U26727	1174	CDKN2A	Cell Cycle: G1/S Check Point , CTCF: First Multivalent Nuclear Factor, Cyclins and Cell Cycle Regulation, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc	0.0245577	0.782
259	drug_resistance_and_metabolism_h	BioCarta	H002789_01	Info	Tumor protein p53 (Li-Fraumeni syndrome)	H002789_01	NM_000546	1846	TP53	Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc	0.0273242	1.207
260	drug_resistance_and_metabolism_h	BioCarta	H003759_01	Info	Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	H003759_01	U40343	29656	CDKN2D	Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation	0.0311312	1.253
261	drug_resistance_and_metabolism_h	BioCarta	H002149_01	Info	Cyclin-dependent kinase inhibitor 1A (p21, Cip1)	H002149_01	U03106	179665	CDKN1A	ATM Signaling Pathway, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, Effects of calcineurin in Keratinocyte Differentiation, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia and p53 in the Cardiovascular system, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, immunology, tsonc	0.0349766	1.236
262	drug_resistance_and_metabolism_h	BioCarta	H002424_01	Info	Bleomycin hydrolase	H002424_01	X92106	78943	BLMH	immunology, pharmacology	0.0414602	0.81
263	drug_resistance_and_metabolism_h	BioCarta	H007820_01	Info	Retinoic acid receptor-beta associated open reading frame	H007820_01	S82362	1938	LOC51036	Control of Gene Expression by Vitamin D Receptor, DNA_adducts, DNA_damage, gene_regulation, transcription	0.0421365	0.794
264	drug_resistance_and_metabolism_h	BioCarta	H003156_01	Info	V-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptid	H003156_01	M83221	858	RELB	tsonc	0.0527226	1.209
265	drug_resistance_and_metabolism_h	BioCarta	H007892_01	Info	Cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19	H007892_01	M61854	198501	CYP2C19	Fatty acid metabolism, gamma-Hexachlorocyclohexane degradation, Tryptophan metabolism, pharmacology	0.0560255	0.801
266	drug_resistance_and_metabolism_h	BioCarta	H003713_01	Info	Topoisomerase (DNA) II beta (180kD)	H003713_01	X68060	75248	TOP2B	Control of Gene Expression by Vitamin D Receptor, DNA_adducts, DNA_damage, gene_regulation, transcription	0.075384	0.83
267	drug_resistance_and_metabolism_h	BioCarta	H002473_01	Info	Insulin-like growth factor 1 receptor	H002473_01	NM_000875	239176	IGF1R	Perou's- Intrinsic- Breast-Cancer-Genes, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Erk1/Erk2 Mapk Signaling pathway, IGF-1 Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Telomeres, Telomerase, Cellular Aging, and Immortality, The IGF-1 Receptor and Longevity, immunology	0.079692	1.158
268	drug_resistance_and_metabolism_h	BioCarta	H003600_01	Info	Epoxide hydrolase 2, cytoplasmic	H003600_01	L05779	113	EPHX2	Tetrachloroethene degradation, immunology, metabolism, pharmacology	0.092835	0.858
269	drug_resistance_and_metabolism_h	BioCarta	H002323_01	Info	Cyclin E1	H002323_01	M74093	9700	CCNE1	Perou's- Intrinsic- Breast-Cancer-Genes, CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression, cell_cycle	0.1107382	0.884
270	drug_resistance_and_metabolism_h	BioCarta	H003376_01	Info	Aryl hydrocarbon receptor nuclear translocator	H003376_01	M69238	166172	ARNT	Ahr Signal Transduction Pathway, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia-Inducible Factor in the Cardiovascular System, VEGF, Hypoxia, and Angiogenesis, angiogenesis, immunology	0.1249479	1.133
271	drug_resistance_and_metabolism_h	BioCarta	H014546_01	Info	Peptidylprolyl isomerase A (cyclophilin A)	H014546_01	NM_021130	182937	PPIA	IL-2 Receptor Beta Chain in T cell Activation	0.129858	1.176
272	drug_resistance_and_metabolism_h	BioCarta	H003023_01	Info	Dihydrofolate reductase	H003023_01	NM_000791	83765	DHFR	Cell Cycle: G1/S Check Point , Folate biosynthesis, One carbon pool by folate, immunology, pharmacology	0.1336155	0.862
273	drug_resistance_and_metabolism_h	BioCarta	H003550_01	Info	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	H003550_01	S76638	73090	NFKB2	gene_regulation, immunology, transcription, tsonc	0.1593331	1.165
274	drug_resistance_and_metabolism_h	BioCarta	H001986_01	Info	Aryl hydrocarbon receptor	H001986_01	NM_001621	170087	AHR	Ahr Signal Transduction Pathway, gene_regulation, immunology, transcription	0.1792938	1.117
275	drug_resistance_and_metabolism_h	BioCarta	H002091_01	Info	V-myc avian myelocytomatosis viral oncogene homolog	H002091_01	K02276	79070	MYC	Cadmium induces DNA synthesis and proliferation in macrophages, CTCF: First Multivalent Nuclear Factor, Erk1/Erk2 Mapk Signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, MAPKinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, WNT Signaling Pathway, gene_regulation, immunology, transcription, tsonc	0.1797519	0.824
276	drug_resistance_and_metabolism_h	BioCarta	H003810_01	Info	Superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))	H003810_01	X02317	75428	SOD1	Cardiac Protection Against ROS , Free Radical Induced Apoptosis, immunology, pharmacology	0.1871555	1.13
277	drug_resistance_and_metabolism_h	BioCarta	H003242_01	Info	Excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pig	H003242_01	M31899	77929	ERCC3	CARM1 and Regulation of the Estrogen Receptor, Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes, Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, DNA_damage, DNA_replication, immunology	0.2157492	0.873
278	drug_resistance_and_metabolism_h	BioCarta	H003042_01	Info	BCL2-like 1	H003042_01	Z23115	305890	BCL2L1	Apoptotic Signaling in Response to DNA Damage, IL-2 Receptor Beta Chain in T cell Activation, Opposing roles of AIF in Apoptosis and Cell Survival, Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, immunology	0.2336065	1.143
279	drug_resistance_and_metabolism_h	BioCarta	H003605_01	Info	BCL2-associated X protein	H003605_01	L22474	159428	BAX	Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology	0.253339	0.907
280	drug_resistance_and_metabolism_h	BioCarta	H003514_01	Info	Cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2	H003514_01	M55053	1361	CYP1A2	Mechanism of Acetaminophen Activity and Toxicity, Nuclear Receptors in Lipid Metabolism and Toxicity, Fatty acid metabolism, gamma-Hexachlorocyclohexane degradation, Tryptophan metabolism, immunology, pharmacology	0.2704204	1.089
281	drug_resistance_and_metabolism_h	BioCarta	H011468_01	Info	ATP-binding cassette, sub-family G (WHITE), member 2	H011468_01	AF103796	194720	ABCG2		0.2713892	0.876
282	drug_resistance_and_metabolism_h	BioCarta	H002577_01	Info	MutL (E. coli) homolog 1 (colon cancer, nonpolyposis type 2)	H002577_01	U07418	57301	MLH1	DNA_damage, DNA_replication, tsonc	0.2947975	0.894
283	drug_resistance_and_metabolism_h	BioCarta	H003016_01	Info	Insulin-like growth factor 2 receptor	H003016_01	Y00285	76473	IGF2R	immunology	0.3174469	1.143
284	drug_resistance_and_metabolism_h	BioCarta	H001999_01	Info	Cyclin D1 (PRAD1: parathyroid adenomatosis 1)	H001999_01	X59798	82932	CCND1	Perou's- Intrinsic- Breast-Cancer-Genes, BTG family proteins and cell cycle regulation, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G1/S Check Point , Cyclins and Cell Cycle Regulation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, WNT Signaling Pathway, cell_cycle, tsonc	0.3215316	0.898
285	drug_resistance_and_metabolism_h	BioCarta	H002702_01	Info	Retinoic acid receptor, gamma	H002702_01	M38258	1497	RARG	Nuclear Receptors in Lipid Metabolism and Toxicity, development, gene_regulation, transcription	0.4297075	1.087
286	drug_resistance_and_metabolism_h	BioCarta	H002294_01	Info	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	H002294_01	X78338	89433	ABCC1	Multi-Drug Resistance Factors	0.4691659	0.928
287	drug_resistance_and_metabolism_h	BioCarta	H002907_01	Info	Retinoic acid receptor, alpha	H002907_01	X06614	250505	RARA	Degradation of the RAR and RXR by the proteasome, Map Kinase Inactivation of SMRT Corepressor, Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, Nuclear Receptors in Lipid Metabolism and Toxicity, Regulation of transcriptional activity by PML, Transcription Regulation by Methyltransferase of CARM1, development	0.4825926	1.084
288	drug_resistance_and_metabolism_h	BioCarta	H000149_01	Info	Epoxide hydrolase 1, microsomal (xenobiotic)	H000149_01	NM_000120	89649	EPHX1	Eicosanoid Metabolism, Tetrachloroethene degradation, immunology, metabolism, pharmacology	0.512274	0.938
289	drug_resistance_and_metabolism_h	BioCarta	H001952_01	Info	Ribosomal protein L13a	H001952_01	X56932	119122	RPL13A		0.565051	1.059
290	drug_resistance_and_metabolism_h	BioCarta	H006635_01	Info	Homo sapiens clone 23607 mRNA sequence	H006635_01	AF038181	167825		ALK in cardiac myocytes, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, Presenilin action in Notch and Wnt signaling, TGF beta signaling pathway, WNT Signaling Pathway, development, immunology, tsonc	0.6181322	1.041
291	drug_resistance_and_metabolism_h	BioCarta	H002777_01	Info	Cytochrome P450, subfamily IIE (ethanol-inducible)	H002777_01	J02625	75183	CYP2E	Mechanism of Acetaminophen Activity and Toxicity, Nuclear Receptors in Lipid Metabolism and Toxicity, Fatty acid metabolism, gamma-Hexachlorocyclohexane degradation, Tryptophan metabolism	0.6229802	0.953
292	drug_resistance_and_metabolism_h	BioCarta	H003538_01	Info	Actin, beta	H003538_01	NM_001101	288061	ACTB	Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes	0.6253266	0.956
293	drug_resistance_and_metabolism_h	BioCarta	H013267_01	Info	Homo sapiens clone R2 ErbB-3 R2 (c-erbB-3) mRNA, partial cds	H013267_01	U88358	306251		Neuroregulin receptor degredation protein-1 Controls ErbB3 receptor recycling, Role of ERBB2 in Signal Transduction and Oncology, cell_cycle, cell_signaling, signal_transduction, tsonc	0.6380266	1.054
294	drug_resistance_and_metabolism_h	BioCarta	H001853_01	Info	Cellular retinoic acid-binding protein 1	H001853_01	S74445	7678	CRABP1	Perou's- Intrinsic- Breast-Cancer-Genes	0.6817674	0.954
295	drug_resistance_and_metabolism_h	BioCarta	H002094_01	Info	Thymidylate synthetase	H002094_01	X02308	82962	TYMS	One carbon pool by folate, Pyrimidine metabolism, metabolism, pharmacology	0.6945693	1.041
296	drug_resistance_and_metabolism_h	BioCarta	H002029_01	Info	V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3	H002029_01	M34309	199067	ERBB3	Neuroregulin receptor degredation protein-1 Controls ErbB3 receptor recycling, Role of ERBB2 in Signal Transduction and Oncology, cell_cycle, cell_signaling, signal_transduction, tsonc	0.7019431	1.035
297	drug_resistance_and_metabolism_h	BioCarta	H003542_01	Info	V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene	H003542_01	M11730	323910	ERBB2	Perou's- Intrinsic- Breast-Cancer-Genes, Role of ERBB2 in Signal Transduction and Oncology, Trefoil Factors Initiate Mucosal Healing, immunology, signal_transduction, tsonc	0.7160857	1.031
298	drug_resistance_and_metabolism_h	BioCarta	H003482_01	Info	Catechol-O-methyltransferase	H003482_01	NM_000754	240013	COMT	Tyrosine metabolism, behavior, immunology	0.777803	1.026
299	drug_resistance_and_metabolism_h	BioCarta	H006841_01	Info	Homo sapiens mRNA; cDNA DKFZp564P073 (from clone DKFZp564P073)	H006841_01	AL049301	278577		Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology	0.7810094	0.98
300	drug_resistance_and_metabolism_h	BioCarta	H000245_01	Info	Peroxisome proliferative activated receptor, gamma	H000245_01	L40904	100724	PPARG	Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Nuclear Receptors in Lipid Metabolism and Toxicity, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, Visceral Fat Deposits and the Metabolic Syndrome	0.7837641	0.944
301	drug_resistance_and_metabolism_h	BioCarta	H003772_01	Info	Xeroderma pigmentosum, complementation group C	H003772_01	D21089	320	XPC	DNA_damage, immunology	0.7950726	0.977
302	drug_resistance_and_metabolism_h	BioCarta	H003355_01	Info	Retinoid X receptor, gamma	H003355_01	U38480	26550	RXRG	development	0.8348881	1.017
303	drug_resistance_and_metabolism_h	BioCarta	H001977_01	Info	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	H001977_01	AF085692	90786	ABCC3	Multi-Drug Resistance Factors, Nuclear Receptors in Lipid Metabolism and Toxicity	0.8363263	1.021
304	drug_resistance_and_metabolism_h	BioCarta	H002350_01	Info	Peroxisome proliferative activated receptor, alpha	H002350_01	L02932	998	PPARA	Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Nuclear Receptors in Lipid Metabolism and Toxicity, Regulation of PGC-1a, �-arrestins in GPCR Desensitization, Toll-Like Receptor Pathway	0.8655149	1.015
305	drug_resistance_and_metabolism_h	BioCarta	H003711_01	Info	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)	H003711_01	M58603	83428	NFKB1	Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAPKinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a ...	0.8665095	1.017
306	drug_resistance_and_metabolism_h	BioCarta	H002373_01	Info	MutS (E. coli) homolog 3	H002373_01	U61981	42674	MSH3	DNA_damage, immunology	0.8910817	0.986
307	drug_resistance_and_metabolism_h	BioCarta	H015889_01	Info	BCL2-like 1	H015889_01	NM_001191	305890	BCL2L1	Apoptotic Signaling in Response to DNA Damage, IL-2 Receptor Beta Chain in T cell Activation, Opposing roles of AIF in Apoptosis and Cell Survival, Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, immunology	0.996743	1.001
308	pmlPathway_h	BioCarta	H002420_01	Info	Promyelocytic leukemia	H002420_01	M79462	89633	PML	Regulation of transcriptional activity by PML, gene_regulation, immunology, transcription	0.0004143	0.71
309	pmlPathway_h	BioCarta	H003112_01	Info	Retinoblastoma 1 (including osteosarcoma)	H003112_01	L41870	75770	RB1	BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc	0.0008596	0.674
310	pmlPathway_h	BioCarta	H000570_01	Info	CREB binding protein (Rubinstein-Taybi syndrome)	H000570_01	U47741	23598	CREBBP	gene_regulation, transcription	0.0048718	1.469
311	pmlPathway_h	BioCarta	H002789_01	Info	Tumor protein p53 (Li-Fraumeni syndrome)	H002789_01	NM_000546	1846	TP53	Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc	0.0273242	1.207
312	pmlPathway_h	BioCarta	H002049_01	Info	Death-associated protein 6	H002049_01	AB015051	180224	DAXX	FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , Regulation of transcriptional activity by PML, Stress Induction of HSP Regulation, apoptosis	0.0788021	1.159
313	pmlPathway_h	BioCarta	H002506_01	Info	Tumor necrosis factor receptor superfamily, member 1B	H002506_01	M32315	256278	TNFRSF1B	TNFR2 Signaling Pathway, immunology	0.1166754	1.17
314	pmlPathway_h	BioCarta	H007835_01	Info	Sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 1	H007835_01	NM_012238	31176	SIRT1	Regulation of transcriptional activity by PML	0.2402857	0.874
315	pmlPathway_h	BioCarta	H003644_01	Info	Tumor necrosis factor receptor superfamily, member 6	H003644_01	X63717	82359	TNFRSF6	apoptosis, immunology	0.4621499	0.927
316	pmlPathway_h	BioCarta	H002907_01	Info	Retinoic acid receptor, alpha	H002907_01	X06614	250505	RARA	Degradation of the RAR and RXR by the proteasome, Map Kinase Inactivation of SMRT Corepressor, Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, Nuclear Receptors in Lipid Metabolism and Toxicity, Regulation of transcriptional activity by PML, Transcription Regulation by Methyltransferase of CARM1, development	0.4825926	1.084
317	pmlPathway_h	BioCarta	H000554_01	Info	Nuclear antigen Sp100	H000554_01	AF056322	77617	SP100	Regulation of transcriptional activity by PML, gene_regulation, transcription	0.8369981	0.979
318	EGF_receptor_signaling_pathway_h	BioCarta	H002040_01	Info	Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)	H002040_01	X00588	77432	EGFR	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degredation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc	0.0004362	0.669
319	EGF_receptor_signaling_pathway_h	BioCarta	H002055_01	Info	Growth factor receptor-bound protein 2	H002055_01	M96995	296381	GRB2	Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...	0.0022348	1.459
320	EGF_receptor_signaling_pathway_h	BioCarta	H011186_01	Info	Growth factor receptor-bound protein 7	H011186_01	D43772	86859	GRB7	Perou's- Intrinsic- Breast-Cancer-Genes	0.0262471	0.742
321	EGF_receptor_signaling_pathway_h	BioCarta	H000928_01	Info	Epiregulin	H000928_01	D30783	115263	EREG		0.1139333	0.813
322	EGF_receptor_signaling_pathway_h	BioCarta	H010696_01	Info	NCK adaptor protein 2	H010696_01	AF047487	101695	NCK2		0.1245534	1.19
323	EGF_receptor_signaling_pathway_h	BioCarta	H006546_01	Info	Neuronal Shc	H006546_01	D84361	151123	SHC3		0.1304854	1.158
324	EGF_receptor_signaling_pathway_h	BioCarta	H002156_01	Info	Epidermal growth factor receptor pathway substrate 15	H002156_01	Z29064	79095	EPS15	Endocytotic role of NDK, Phosphins and Dynamin, immunology, misc	0.1357021	0.865
325	EGF_receptor_signaling_pathway_h	BioCarta	H002376_01	Info	Epidermal growth factor receptor pathway substrate 8	H002376_01	U12535	2132	EPS8	misc	0.231316	0.841
326	EGF_receptor_signaling_pathway_h	BioCarta	H002632_01	Info	GRB2-associated binding protein 1	H002632_01	U43885	239706	GAB1	Signaling of Hepatocyte Growth Factor Receptor	0.3021702	1.095
327	GPCRs_Class_A_Rhodopsin-like_h	GO	H002088_01	Info	Prostaglandin E receptor 4 (subtype EP4)	H002088_01	L25124	199248	PTGER4	Eicosanoid Metabolism	0.0029063	0.734
328	GPCRs_Class_A_Rhodopsin-like_h	GO	H004080_01	Info	Histamine receptor H3	H004080_01	NM_007232	251399	HRH3		0.0035969	0.66
329	GPCRs_Class_A_Rhodopsin-like_h	GO	H003668_01	Info	Histamine receptor H1	H003668_01	Z34897	1570	HRH1		0.0076811	0.709
330	GPCRs_Class_A_Rhodopsin-like_h	GO	H002813_01	Info	5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)	H002813_01	U68488	73739	HTR7	immunology	0.0089719	1.292
331	GPCRs_Class_A_Rhodopsin-like_h	GO	H002667_01	Info	Prostaglandin E receptor 1 (subtype EP1), 42kD	H002667_01	L22647	159360	PTGER1	Eicosanoid Metabolism, Phospholipase C-epsilon pathway	0.0102067	1.228
332	GPCRs_Class_A_Rhodopsin-like_h	GO	H003590_01	Info	Retinal G protein coupled receptor	H003590_01	U14910	1544	RGR		0.0153777	1.301
333	GPCRs_Class_A_Rhodopsin-like_h	GO	H002494_01	Info	Adrenergic, alpha-1B-, receptor	H002494_01	U03865	123055	ADRA1B	Phospholipase C d1 in phospholipid associated cell signaling	0.0200341	1.572
334	GPCRs_Class_A_Rhodopsin-like_h	GO	H002167_01	Info	Chemokine binding protein 2	H002167_01	U94888	117572	CCBP2		0.0225142	0.731
335	GPCRs_Class_A_Rhodopsin-like_h	GO	H002027_01	Info	Prostaglandin I2 (prostacyclin) receptor (IP)	H002027_01	D25418	393	PTGIR	Eicosanoid Metabolism, immunology	0.0236242	0.789
336	GPCRs_Class_A_Rhodopsin-like_h	GO	H003343_01	Info	Galanin receptor 1	H003343_01	NM_001480	272191	GALR1		0.0260438	0.759
337	GPCRs_Class_A_Rhodopsin-like_h	GO	H002347_01	Info	Leukotriene b4 receptor (chemokine receptor-like 1)	H002347_01	D89078	28408	LTB4R	immunology	0.0284508	1.35
338	GPCRs_Class_A_Rhodopsin-like_h	GO	H003130_01	Info	Interleukin 8 receptor, beta	H003130_01	L19593	846	IL8RB	immunology	0.0345675	1.307
339	GPCRs_Class_A_Rhodopsin-like_h	GO	H002464_01	Info	G protein-coupled receptor 2	H002464_01	AF215981	278446	GPR2	immunology	0.0493902	0.772
340	GPCRs_Class_A_Rhodopsin-like_h	GO	H006487_01	Info	Neuropeptide Y receptor Y6 (pseudogene)	H006487_01	D86519	73086	NPY6R		0.0535714	1.212
341	GPCRs_Class_A_Rhodopsin-like_h	GO	H003428_01	Info	5-hydroxytryptamine (serotonin) receptor 2A	H003428_01	X57830	298623	HTR2A	immunology	0.0558704	1.169
342	GPCRs_Class_A_Rhodopsin-like_h	GO	H002592_01	Info	Opioid receptor, mu 1	H002592_01	L25119	2353	OPRM1	behavior, immunology	0.0609704	0.812
343	GPCRs_Class_A_Rhodopsin-like_h	GO	H003745_01	Info	Neuropeptide Y receptor Y1	H003745_01	NM_000909	169266	NPY1R	Perou's- Intrinsic- Breast-Cancer-Genes, immunology	0.0754043	1.285
344	GPCRs_Class_A_Rhodopsin-like_h	GO	H002332_01	Info	Bradykinin receptor B2	H002332_01	NM_000623	250882	BDKRB2	Actions of Nitric Oxide in the Heart, angiogenesis, immunology	0.0806551	0.852
345	GPCRs_Class_A_Rhodopsin-like_h	GO	H003670_01	Info	Adrenergic, beta-1-, receptor	H003670_01	J03019	99913	ADRB1	behavior, immunology	0.0878218	1.205
346	GPCRs_Class_A_Rhodopsin-like_h	GO	H002366_01	Info	Chemokine (C-C motif) receptor 9	H002366_01	NM_006641	225946	CCR9		0.0908646	1.196
347	GPCRs_Class_A_Rhodopsin-like_h	GO	H002585_01	Info	G protein-coupled receptor 17	H002585_01	Z94155	46453	GPR17		0.1077387	1.234
348	GPCRs_Class_A_Rhodopsin-like_h	GO	H002758_01	Info	Chemokine-like receptor 1	H002758_01	U79526	159553	CMKLR1	immunology	0.1103372	1.187
349	GPCRs_Class_A_Rhodopsin-like_h	GO	H003899_01	Info	Chemokine (C-C motif) receptor 1	H003899_01	D10925	301921	CCR1	Selective expression of chemokine receptors during T-cell polarization, immunology	0.1258208	1.15
350	GPCRs_Class_A_Rhodopsin-like_h	GO	H002321_01	Info	G protein-coupled receptor 30	H002321_01	AF015257	113207	GPR30	immunology	0.1344665	1.164
351	GPCRs_Class_A_Rhodopsin-like_h	GO	H015702_01	Info	G protein-coupled receptor 44	H015702_01	NM_004778	299567	GPR44		0.1450231	1.171
352	GPCRs_Class_A_Rhodopsin-like_h	GO	H002567_01	Info	Thyroid stimulating hormone receptor	H002567_01	M31774	123078	TSHR	immunology	0.1458901	0.876
353	GPCRs_Class_A_Rhodopsin-like_h	GO	H002097_01	Info	Dopamine receptor D2	H002097_01	X51362	73893	DRD2	behavior, immunology	0.1531006	0.865
354	GPCRs_Class_A_Rhodopsin-like_h	GO	H002110_01	Info	Coagulation factor II (thrombin) receptor	H002110_01	NM_001992	128087	F2R	Perou's- Intrinsic- Breast-Cancer-Genes, Acute Myocardial Infarction, Extrinsic Prothrombin Activation Pathway, Fibrinolysis Pathway, Intrinsic Prothrombin Activation Pathway, immunology	0.1560498	0.883
355	GPCRs_Class_A_Rhodopsin-like_h	GO	H002476_01	Info	Chemokine (C-C motif) receptor 5	H002476_01	NM_000579	54443	CCR5	HIV Induced T Cell Apoptosis, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, NO2-dependent IL 12 Pathway in NK cells, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Selective expression of chemokine receptors during T-cell polarization, immunology	0.1574808	0.842
356	GPCRs_Class_A_Rhodopsin-like_h	GO	H015524_01	Info	AD026 protein	H015524_01	NM_020683	28847	AD026		0.1577677	1.184
357	GPCRs_Class_A_Rhodopsin-like_h	GO	H002454_01	Info	Follicle stimulating hormone receptor	H002454_01	M65085	1428	FSHR	Regulation of Spermatogenesis by CREM	0.1580303	1.111
358	GPCRs_Class_A_Rhodopsin-like_h	GO	H002487_01	Info	Complement component 5 receptor 1 (C5a ligand)	H002487_01	M62505	2161	C5R1	immunology	0.1622511	1.213
359	GPCRs_Class_A_Rhodopsin-like_h	GO	H000667_01	Info	Purinergic receptor (family A group 5)	H000667_01	AF000546	189999	P2Y5		0.1930389	0.884
360	GPCRs_Class_A_Rhodopsin-like_h	GO	H009013_01	Info	Dopamine receptor D2	H009013_01	AF176812	73893	DRD2	behavior, immunology	0.2238033	1.119
361	GPCRs_Class_A_Rhodopsin-like_h	GO	H003535_01	Info	Galanin receptor 3	H003535_01	AF073799	158353	GALR3		0.227577	1.12
362	GPCRs_Class_A_Rhodopsin-like_h	GO	H003381_01	Info	Melatonin receptor 1A	H003381_01	U14108	248147	MTNR1A		0.3138134	1.113
363	GPCRs_Class_A_Rhodopsin-like_h	GO	H015755_01	Info	Chemokine (C-C motif) receptor 1	H015755_01	NM_001295	301921	CCR1	Selective expression of chemokine receptors during T-cell polarization, immunology	0.3366567	1.129
364	GPCRs_Class_A_Rhodopsin-like_h	GO	H006918_01	Info	Neuropeptide G protein-coupled receptor; neuropeptide FF 2	H006918_01	NM_004885	99231	NPGPR		0.4203767	0.905
365	GPCRs_Class_A_Rhodopsin-like_h	GO	H002976_01	Info	G protein-coupled receptor 9	H002976_01	X95876	198252	GPR9	IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, mCalpain and friends in Cell motility, NO2-dependent IL 12 Pathway in NK cells, Selective expression of chemokine receptors during T-cell polarization	0.4390046	0.918
366	GPCRs_Class_A_Rhodopsin-like_h	GO	H002698_01	Info	Adrenergic, beta-3-, receptor	H002698_01	NM_000025	2549	ADRB3	behavior, immunology	0.4399337	0.93
367	GPCRs_Class_A_Rhodopsin-like_h	GO	H010325_01	Info	Chemokine (C-C motif) receptor-like 2	H010325_01	AF015525	302043	CCRL2		0.4610352	0.915
368	GPCRs_Class_A_Rhodopsin-like_h	GO	H002378_01	Info	Adrenergic, alpha-2C-, receptor	H002378_01	J03853	123022	ADRA2C	behavior, immunology	0.4753686	1.073
369	GPCRs_Class_A_Rhodopsin-like_h	GO	H003577_01	Info	Adrenergic, alpha-1A-, receptor	H003577_01	D32202	52931	ADRA1A	behavior	0.5296756	1.062
370	GPCRs_Class_A_Rhodopsin-like_h	GO	H003424_01	Info	Chemokine (C-C motif) receptor 3	H003424_01	U28694	158324	CCR3	CCR3 signaling in Eosinophils, IL 5 Signaling Pathway, Selective expression of chemokine receptors during T-cell polarization, The Role of Eosinophils in the Chemokine Network of Allergy, immunology	0.5671442	1.138
371	GPCRs_Class_A_Rhodopsin-like_h	GO	H007948_01	Info	F-box and WD-40 domain protein 2	H007948_01	NM_012164	13755	FBXW2		0.5814024	1.048
372	GPCRs_Class_A_Rhodopsin-like_h	GO	H003584_01	Info	Platelet-activating factor receptor	H003584_01	D10202	46	PTAFR	angiogenesis, immunology	0.5977382	1.05
373	GPCRs_Class_A_Rhodopsin-like_h	GO	H003654_01	Info	Coagulation factor II (thrombin) receptor-like 2	H003654_01	U92971	194351	F2RL2	immunology	0.6746058	0.966
374	GPCRs_Class_A_Rhodopsin-like_h	GO	H002380_01	Info	Chemokine (C-C motif) receptor 8	H002380_01	D49919	113222	CCR8	immunology	0.6915296	1.035
375	GPCRs_Class_A_Rhodopsin-like_h	GO	H002317_01	Info	Chemokine (C-X3-C) receptor 1	H002317_01	U20350	78913	CX3CR1	immunology	0.7275779	1.038
376	GPCRs_Class_A_Rhodopsin-like_h	GO	H016261_01	Info	Putative G protein-coupled receptor 92	H016261_01	NM_020400	330563	GPR92		0.7713793	0.962
377	GPCRs_Class_A_Rhodopsin-like_h	GO	H012371_01	Info	Thyroid stimulating hormone receptor	H012371_01	S82807	123078	TSHR	immunology	0.7783963	1.03
378	GPCRs_Class_A_Rhodopsin-like_h	GO	H003426_01	Info	Prostaglandin D2 receptor (DP)	H003426_01	U31099	158326	PTGDR		0.800069	0.971
379	GPCRs_Class_A_Rhodopsin-like_h	GO	H003721_01	Info	Dopamine receptor D4	H003721_01	L12398	99922	DRD4	behavior, immunology	0.8251335	1.023
380	GPCRs_Class_A_Rhodopsin-like_h	GO	H002672_01	Info	G protein-coupled receptor	H002672_01	U67784	23016	RDC1		0.8527585	0.967
381	GPCRs_Class_A_Rhodopsin-like_h	GO	H003854_01	Info	Burkitt lymphoma receptor 1, GTP-binding protein	H003854_01	X68149	113916	BLR1		0.882872	0.982
382	GPCRs_Class_A_Rhodopsin-like_h	GO	H002271_01	Info	Neuropeptide Y receptor Y2	H002271_01	NM_000910	37125	NPY2R		0.9438408	0.993
383	GPCRs_Class_A_Rhodopsin-like_h	GO	H002797_01	Info	Adenosine A3 receptor	H002797_01	NM_000677	258	ADORA3		0.9481775	0.993
384	GPCRs_Class_A_Rhodopsin-like_h	GO	H002327_01	Info	Adenosine A1 receptor	H002327_01	L22214	77867	ADORA1	immunology	0.9613941	1.005

Table - Significant pathway by running the Hotelling T-square test consist of the following genes (sorted by p-values).


	Broad Pathway	Pathway description	Unique id	Anno- tations	Description	Clone	GB acc	UG cluster	Gene symbol	Defined genelists	Parametric p-value	Geometric mean of ratios (class Disesase /class Normal )
1	spryPathway_h	BioCarta	H002040_01	Info	Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)	H002040_01	X00588	77432	EGFR	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degredation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc	0.0004362	0.669
2	spryPathway_h	BioCarta	H002055_01	Info	Growth factor receptor-bound protein 2	H002055_01	M96995	296381	GRB2	Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...	0.0022348	1.459
3	spryPathway_h	BioCarta	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
4	spryPathway_h	BioCarta	H002847_01	Info	Protein tyrosine phosphatase, receptor type, B	H002847_01	X54131	123641	PTPRB	Sprouty regulation of tyrosine kinase signals, cell_cycle, cell_signaling	0.0110757	1.299
5	spryPathway_h	BioCarta	H003178_01	Info	Mitogen-activated protein kinase 3	H003178_01	X60188	861	MAPK3	Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...	0.0986041	1.184
6	spryPathway_h	BioCarta	H001600_01	Info	RAS p21 protein activator (GTPase activating protein) 1	H001600_01	M23379	758	RASA1	EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction	0.1015906	0.844
7	spryPathway_h	BioCarta	H002722_01	Info	Mitogen-activated protein kinase kinase 1	H002722_01	L11284	3446	MAP2K1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...	0.7377933	0.973
8	ST_p38_MAPK_Pathway_h	Signalling Transduction KE	H003352_01	Info	Interleukin 1 receptor, type I	H003352_01	M27492	82112	IL1R1	NF-kB Signaling Pathway, Signal transduction through IL1R, immunology	0.000502	0.677
9	ST_p38_MAPK_Pathway_h	Signalling Transduction KE	H003200_01	Info	Mitogen-activated protein kinase kinase 3	H003200_01	D87116	180533	MAP2K3	fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway	0.0009666	1.561
10	ST_p38_MAPK_Pathway_h	Signalling Transduction KE	H002186_01	Info	Serum response factor (c-fos serum response element-binding transcription factor)	H002186_01	J03161	155321	SRF	EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription	0.0017465	0.722
11	ST_p38_MAPK_Pathway_h	Signalling Transduction KE	H000309_01	Info	CAMP response element-binding protein CRE-BPa	H000309_01	L05515	149	H_GS165L15.1		0.0078273	1.479
12	ST_p38_MAPK_Pathway_h	Signalling Transduction KE	H002895_01	Info	Mitogen-activated protein kinase 14	H002895_01	L35263	79107	MAPK14	BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAPKinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm ...	0.0086925	1.429
13	ST_p38_MAPK_Pathway_h	Signalling Transduction KE	H003611_01	Info	Mitogen-activated protein kinase kinase 4	H003611_01	L36870	75217	MAP2K4	Perou's- Intrinsic- Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system	0.012502	0.753
14	ST_p38_MAPK_Pathway_h	Signalling Transduction KE	H003008_01	Info	Mitogen-activated protein kinase kinase kinase 4	H003008_01	AF002715	32353	MAP3K4	MAPKinase Signaling Pathway, Phosphatidylinositol signaling system	0.0127738	0.707
15	ST_p38_MAPK_Pathway_h	Signalling Transduction KE	H004258_01	Info	Elongation factor-2 kinase	H004258_01	U93850	259855	HSU93850	Eukaryotic protein translation	0.0132437	0.748
16	ST_p38_MAPK_Pathway_h	Signalling Transduction KE	H011228_01	Info	G protein-coupled receptor kinase 7	H011228_01	AL137615	261828	GPRK7	Perou's- Intrinsic- Breast-Cancer-Genes, Erk1/Erk2 Mapk Signaling pathway, MAPKinase Signaling Pathway, Phosphatidylinositol signaling system	0.0572981	1.27
17	ST_p38_MAPK_Pathway_h	Signalling Transduction KE	H003107_01	Info	Mitogen-activated protein kinase 13	H003107_01	AF004709	178695	MAPK13	Keratinocyte Differentiation, MAPKinase Signaling Pathway, Stathmin and breast cancer resistance to antimicrotubule agents, Phosphatidylinositol signaling system	0.0717244	1.171
18	ST_p38_MAPK_Pathway_h	Signalling Transduction KE	H008351_01	Info	Dual specificity phosphatase 10	H008351_01	AB026436	177534	DUSP10		0.382916	0.922
19	ST_p38_MAPK_Pathway_h	Signalling Transduction KE	H006851_01	Info	TAK1-binding protein 2; KIAA0733 protein	H006851_01	AL117407	109727	KIAA0733	Toll-Like Receptor Pathway	0.4908732	1.066
20	ST_p38_MAPK_Pathway_h	Signalling Transduction KE	H002340_01	Info	Mitogen-activated protein kinase kinase kinase 5	H002340_01	U67156	151988	MAP3K5	HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , The 4-1BB-dependent immune response	0.5393151	1.07
21	ST_p38_MAPK_Pathway_h	Signalling Transduction KE	H002173_01	Info	Cell division cycle 42 (GTP-binding protein, 25kD)	H002173_01	AL121735	146409	CDC42	Agrin in Postsynaptic Differentiation, How does salmonella hijack a cell, p38 MAPK Signaling Pathway , Ras Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, cell_cycle, cell_signaling, signal_transduction	0.6486191	1.035
22	ST_p38_MAPK_Pathway_h	Signalling Transduction KE	H003612_01	Info	V-akt murine thymoma viral oncogene homolog 1	H003612_01	M63167	71816	AKT1	Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signalling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation ...	0.6741257	1.038
23	ST_p38_MAPK_Pathway_h	Signalling Transduction KE	H001386_01	Info	Mitogen-activated protein kinase kinase kinase 10	H001386_01	X90846	30223	MAP3K10	MAPKinase Signaling Pathway, Phosphatidylinositol signaling system	0.7007387	0.968
24	ST_p38_MAPK_Pathway_h	Signalling Transduction KE	H003434_01	Info	Dual specificity phosphatase 1	H003434_01	NM_004417	171695	DUSP1	CD40L Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, TNFR2 Signaling Pathway	0.8183145	0.968
25	ST_p38_MAPK_Pathway_h	Signalling Transduction KE	H003711_01	Info	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)	H003711_01	M58603	83428	NFKB1	Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAPKinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a ...	0.8665095	1.017
26	ST_p38_MAPK_Pathway_h	Signalling Transduction KE	H003163_01	Info	CAMP responsive element binding protein 1	H003163_01	M27691	79194	CREB1	Ca++/ Calmodulin-dependent Protein Kinase Activation, Calcium Signaling by HBx of Hepatitis B virus, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia-Inducible Factor in the Cardiovascular System, Inhibition of Huntington\'s disease neurodegeneration by histone deacetylase inhibitors, MAPKinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Repression of Pain Sensation by the Transcriptional Regulator DREAM, Role of Erk5 in Neuronal Survival, Signaling Pathway from G-Protein Families, Transcription factor CREB and its extracellular signals, Transcription Regulation by Methyltransferase of CARM1, immunology	0.9300928	1.009
27	ST_p38_MAPK_Pathway_h	Signalling Transduction KE	H012856_01	Info	MAP kinase-interacting serine/threonine kinase 1	H012856_01	AB000409	5591	MKNK1	Erk1/Erk2 Mapk Signaling pathway, MAPKinase Signaling Pathway, mTOR Signaling Pathway, p38 MAPK Signaling Pathway , Regulation of eIF4e and p70 S6 Kinase, Phosphatidylinositol signaling system	0.9455231	0.992
28	EMT_UP_h	Jechlinger_et_al_2003	H003225_01	Info	Interferon regulatory factor 7	H003225_01	AF076494	166120	IRF7	gene_regulation, transcription	6.44e-05	1.728
29	EMT_UP_h	Jechlinger_et_al_2003	H000825_01	Info	S100 calcium-binding protein A8 (calgranulin A)	H000825_01	X06234	100000	S100A8	immunology	0.0001788	2.746
30	EMT_UP_h	Jechlinger_et_al_2003	H001850_01	Info	Interferon-stimulated protein, 15 kDa	H001850_01	M13755	833	ISG15		0.0003862	1.943
31	EMT_UP_h	Jechlinger_et_al_2003	H000473_01	Info	Uridine phosphorylase	H000473_01	X90858	77573	UP	Pyrimidine metabolism	0.0005102	1.339
32	EMT_UP_h	Jechlinger_et_al_2003	H002726_01	Info	B-cell CLL/lymphoma 3	H002726_01	M31732	31210	BCL3	tsonc	0.0147426	1.351
33	EMT_UP_h	Jechlinger_et_al_2003	H003466_01	Info	CD68 antigen	H003466_01	S57235	246381	CD68	angiogenesis, immunology, metastasis	0.0179458	1.335
34	EMT_UP_h	Jechlinger_et_al_2003	H003299_01	Info	Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	H003299_01	M59979	88474	PTGS1	Aspirin Blocks Signaling Pathway Involved in Platelet Activation, Eicosanoid Metabolism, Mechanism of Acetaminophen Activity and Toxicity, Prostaglandin and leukotriene metabolism, immunology	0.023304	0.813
35	EMT_UP_h	Jechlinger_et_al_2003	H003029_01	Info	Disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein)	H003029_01	U53446	81988	DAB2		0.0291633	0.78
36	EMT_UP_h	Jechlinger_et_al_2003	H003752_01	Info	Platelet-derived growth factor receptor, beta polypeptide	H003752_01	J03278	76144	PDGFRB	cell_cycle, cell_signaling, immunology, misc, signal_transduction	0.0333891	0.832
37	EMT_UP_h	Jechlinger_et_al_2003	H006885_01	Info	Ribonuclease 6 precursor	H006885_01	NM_003730	8297	RNASE6PL		0.0955467	1.208
38	EMT_UP_h	Jechlinger_et_al_2003	H000998_01	Info	Solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	H000998_01	AB018010	79748	SLC3A2	Perou's- Intrinsic- Breast-Cancer-Genes	0.1156436	0.843
39	EMT_UP_h	Jechlinger_et_al_2003	H001908_01	Info	Discoidin domain receptor family, member 2	H001908_01	X74764	71891	DDR2		0.1167676	0.839
40	EMT_UP_h	Jechlinger_et_al_2003	H001001_01	Info	Procollagen C-endopeptidase enhancer	H001001_01	NM_002593	202097	PCOLCE		0.1228497	0.868
41	EMT_UP_h	Jechlinger_et_al_2003	H000774_01	Info	Collagen, type VI, alpha 1	H000774_01	X15880	108885	COL6A1		0.1448402	0.841
42	EMT_UP_h	Jechlinger_et_al_2003	H002775_01	Info	Platelet-derived growth factor receptor, alpha polypeptide	H002775_01	M21574	74615	PDGFRA	Perou's- Intrinsic- Breast-Cancer-Genes, CBL mediated ligand-induced downregulation of EGF receptors, Erk1/Erk2 Mapk Signaling pathway, PDGF Signaling Pathway, Phospholipids as signalling intermediaries, Rac 1 cell motility signaling pathway, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, immunology, signal_transduction	0.1636921	1.107
43	EMT_UP_h	Jechlinger_et_al_2003	H010646_01	Info	Ribonuclease 6 precursor	H010646_01	AK001769	8297	RNASE6PL		0.1872503	1.127
44	EMT_UP_h	Jechlinger_et_al_2003	H002295_01	Info	Adenosine deaminase	H002295_01	X02994	1217	ADA	Purine metabolism, gene_regulation, immunology, transcription	0.1882263	0.871
45	EMT_UP_h	Jechlinger_et_al_2003	H012626_01	Info	Beta-2-microglobulin	H012626_01	AB021288	75415	B2M	Antigen Processing and Presentation, CTL mediated immune response against target cells , Ras-Independent pathway in NK cell-mediated cytotoxicity, immunology	0.1923361	1.156
46	EMT_UP_h	Jechlinger_et_al_2003	H003645_01	Info	Interleukin 11	H003645_01	X58377	1721	IL11	Cytokines and Inflammatory Response, Erythrocyte Differentiation Pathway, Regulation of hematopoiesis by cytokines, immunology	0.2074062	1.116
47	EMT_UP_h	Jechlinger_et_al_2003	H003593_01	Info	Collagen, type VI, alpha 2	H003593_01	AL096746	159263	COL6A2		0.300891	1.098
48	EMT_UP_h	Jechlinger_et_al_2003	H001198_01	Info	Homo sapiens, alpha-1 (VI) collagen	H001198_01	M20776	25459			0.3632512	1.1
49	EMT_UP_h	Jechlinger_et_al_2003	H002451_01	Info	Flavin containing monooxygenase 1	H002451_01	M64082	1424	FMO1	immunology, misc	0.3681883	0.911
50	EMT_UP_h	Jechlinger_et_al_2003	H000592_01	Info	Interferon-induced protein with tetratricopeptide repeats 1	H000592_01	X03557	20315	IFIT1		0.4335751	1.121
51	EMT_UP_h	Jechlinger_et_al_2003	H002713_01	Info	Phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	H002713_01	U24577	93304	PLA2G7	Glycerophospholipid metabolism	0.4631812	0.89
52	EMT_UP_h	Jechlinger_et_al_2003	H010497_01	Info	Interferon induced transmembrane protein 3 (1-8U)	H010497_01	X57352	182241	IFITM3		0.5875785	1.062
53	EMT_UP_h	Jechlinger_et_al_2003	H003695_01	Info	Secreted protein, acidic, cysteine-rich (osteonectin)	H003695_01	J03040	111779	SPARC	misc	0.6414286	1.051
54	EMT_UP_h	Jechlinger_et_al_2003	H002330_01	Info	Cadherin 15, M-cadherin (myotubule)	H002330_01	D83542	148090	CDH15		0.7996949	0.974
55	EMT_UP_h	Jechlinger_et_al_2003	H002397_01	Info	Methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase	H002397_01	X16396	154672	MTHFD2	Glyoxylate and dicarboxylate metabolism, One carbon pool by folate	0.8081788	0.975
56	EMT_UP_h	Jechlinger_et_al_2003	H002672_01	Info	G protein-coupled receptor	H002672_01	U67784	23016	RDC1		0.8527585	0.967
57	EMT_UP_h	Jechlinger_et_al_2003	H002490_01	Info	Hexabrachion (tenascin C, cytotactin)	H002490_01	X78565	289114	HXB	Perou's- Intrinsic- Breast-Cancer-Genes	0.856155	0.983
58	EMT_UP_h	Jechlinger_et_al_2003	H002283_01	Info	Secretory leukocyte protease inhibitor (antileukoproteinase)	H002283_01	X04470	251754	SLPI	Perou's- Intrinsic- Breast-Cancer-Genes, Proepithelin Conversion to Epithelin and Wound Repair Control, immunology	0.9075348	1.012
59	EMT_UP_h	Jechlinger_et_al_2003	H004245_01	Info	Snail 1 (drosophila homolog), zinc finger protein	H004245_01	AF125377	48029	SNAI1	Downregulated of MTA-3 in ER-negative Breast Tumors	0.9743253	1.003
60	egfPathway_h	The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.	H002040_01	Info	Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)	H002040_01	X00588	77432	EGFR	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degredation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc	0.0004362	0.669
61	egfPathway_h	The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.	H002186_01	Info	Serum response factor (c-fos serum response element-binding transcription factor)	H002186_01	J03161	155321	SRF	EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription	0.0017465	0.722
62	egfPathway_h	The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.	H002055_01	Info	Growth factor receptor-bound protein 2	H002055_01	M96995	296381	GRB2	Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...	0.0022348	1.459
63	egfPathway_h	The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
64	egfPathway_h	The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.	H003611_01	Info	Mitogen-activated protein kinase kinase 4	H003611_01	L36870	75217	MAP2K4	Perou's- Intrinsic- Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system	0.012502	0.753
65	egfPathway_h	The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.	H001365_01	Info	Protein kinase C, beta 1	H001365_01	X07109	77202	PRKCB1	Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbal Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction	0.0304335	1.379
66	egfPathway_h	The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.	H003178_01	Info	Mitogen-activated protein kinase 3	H003178_01	X60188	861	MAPK3	Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...	0.0986041	1.184
67	egfPathway_h	The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.	H001600_01	Info	RAS p21 protein activator (GTPase activating protein) 1	H001600_01	M23379	758	RASA1	EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction	0.1015906	0.844
68	egfPathway_h	The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.	H003158_01	Info	Mitogen-activated protein kinase 8	H003158_01	L26318	190913	MAPK8	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...	0.1287835	1.166
69	egfPathway_h	The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.	H001349_01	Info	Janus kinase 1 (a protein tyrosine kinase)	H001349_01	M64174	50651	JAK1	EGF Signaling Pathway, IFN alpha signaling pathway, IFN gamma signaling pathway , IL 2 signaling pathway, IL 4 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, PDGF Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction	0.2754104	1.129
70	egfPathway_h	The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.	H002722_01	Info	Mitogen-activated protein kinase kinase 1	H002722_01	L11284	3446	MAP2K1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...	0.7377933	0.973
71	insulinPathway_h	BioCarta	H000732_01	Info	Insulin receptor substrate 1	H000732_01	S62539	96063	IRS1	Perou's- Intrinsic- Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology	0.0013348	0.643
72	insulinPathway_h	BioCarta	H002186_01	Info	Serum response factor (c-fos serum response element-binding transcription factor)	H002186_01	J03161	155321	SRF	EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription	0.0017465	0.722
73	insulinPathway_h	BioCarta	H002055_01	Info	Growth factor receptor-bound protein 2	H002055_01	M96995	296381	GRB2	Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...	0.0022348	1.459
74	insulinPathway_h	BioCarta	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
75	insulinPathway_h	BioCarta	H003178_01	Info	Mitogen-activated protein kinase 3	H003178_01	X60188	861	MAPK3	Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...	0.0986041	1.184
76	insulinPathway_h	BioCarta	H001600_01	Info	RAS p21 protein activator (GTPase activating protein) 1	H001600_01	M23379	758	RASA1	EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction	0.1015906	0.844
77	insulinPathway_h	BioCarta	H003158_01	Info	Mitogen-activated protein kinase 8	H003158_01	L26318	190913	MAPK8	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...	0.1287835	1.166
78	insulinPathway_h	BioCarta	H002624_01	Info	Insulin receptor	H002624_01	X02160	89695	INSR	Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Growth Hormone Signaling Pathway, Insulin Signaling Pathway, immunology	0.433218	0.919
79	insulinPathway_h	BioCarta	H002722_01	Info	Mitogen-activated protein kinase kinase 1	H002722_01	L11284	3446	MAP2K1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...	0.7377933	0.973
80	igf1Pathway_h	BioCarta	H000732_01	Info	Insulin receptor substrate 1	H000732_01	S62539	96063	IRS1	Perou's- Intrinsic- Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology	0.0013348	0.643
81	igf1Pathway_h	BioCarta	H002186_01	Info	Serum response factor (c-fos serum response element-binding transcription factor)	H002186_01	J03161	155321	SRF	EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription	0.0017465	0.722
82	igf1Pathway_h	BioCarta	H002055_01	Info	Growth factor receptor-bound protein 2	H002055_01	M96995	296381	GRB2	Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...	0.0022348	1.459
83	igf1Pathway_h	BioCarta	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
84	igf1Pathway_h	BioCarta	H002473_01	Info	Insulin-like growth factor 1 receptor	H002473_01	NM_000875	239176	IGF1R	Perou's- Intrinsic- Breast-Cancer-Genes, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Erk1/Erk2 Mapk Signaling pathway, IGF-1 Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Telomeres, Telomerase, Cellular Aging, and Immortality, The IGF-1 Receptor and Longevity, immunology	0.079692	1.158
85	igf1Pathway_h	BioCarta	H003178_01	Info	Mitogen-activated protein kinase 3	H003178_01	X60188	861	MAPK3	Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...	0.0986041	1.184
86	igf1Pathway_h	BioCarta	H001600_01	Info	RAS p21 protein activator (GTPase activating protein) 1	H001600_01	M23379	758	RASA1	EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction	0.1015906	0.844
87	igf1Pathway_h	BioCarta	H003158_01	Info	Mitogen-activated protein kinase 8	H003158_01	L26318	190913	MAPK8	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...	0.1287835	1.166
88	igf1Pathway_h	BioCarta	H002722_01	Info	Mitogen-activated protein kinase kinase 1	H002722_01	L11284	3446	MAP2K1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...	0.7377933	0.973
89	il6Pathway_h	BioCarta	H002186_01	Info	Serum response factor (c-fos serum response element-binding transcription factor)	H002186_01	J03161	155321	SRF	EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription	0.0017465	0.722
90	il6Pathway_h	BioCarta	H002055_01	Info	Growth factor receptor-bound protein 2	H002055_01	M96995	296381	GRB2	Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...	0.0022348	1.459
91	il6Pathway_h	BioCarta	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
92	il6Pathway_h	BioCarta	H003178_01	Info	Mitogen-activated protein kinase 3	H003178_01	X60188	861	MAPK3	Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...	0.0986041	1.184
93	il6Pathway_h	BioCarta	H001349_01	Info	Janus kinase 1 (a protein tyrosine kinase)	H001349_01	M64174	50651	JAK1	EGF Signaling Pathway, IFN alpha signaling pathway, IFN gamma signaling pathway , IL 2 signaling pathway, IL 4 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, PDGF Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction	0.2754104	1.129
94	il6Pathway_h	BioCarta	H002824_01	Info	Janus kinase 3 (a protein tyrosine kinase, leukocyte)	H002824_01	U09607	99877	JAK3	IL 2 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, IL22 Soluble Receptor Signaling Pathway , IL-7 Signal Transduction, Stat3 Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction	0.4735774	1.051
95	il6Pathway_h	BioCarta	H008390_01	Info	Homo sapiens mRNA; cDNA DKFZp564F053 (from clone DKFZp564F053)	H008390_01	AL049265	71968		immunology	0.6157756	1.05
96	il6Pathway_h	BioCarta	H003110_01	Info	Interleukin 6 (interferon, beta 2)	H003110_01	X04430	93913	IL6	Cells and Molecules involved in local acute inflammatory response, Cytokine Network, Cytokines and Inflammatory Response, Erythrocyte Differentiation Pathway, IL 17 Signaling Pathway, IL 5 Signaling Pathway, IL 6 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, Low-density lipoprotein (LDL) pathway during atherogenesis, Regulation of hematopoiesis by cytokines, Role of ERBB2 in Signal Transduction and Oncology, Signal transduction through IL1R, immunology	0.680804	1.036
97	il6Pathway_h	BioCarta	H003456_01	Info	Interleukin 6 receptor	H003456_01	X12830	193400	IL6R	IL 6 signaling pathway, Role of ERBB2 in Signal Transduction and Oncology, immunology	0.7143407	1.03
98	il6Pathway_h	BioCarta	H002722_01	Info	Mitogen-activated protein kinase kinase 1	H002722_01	L11284	3446	MAP2K1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...	0.7377933	0.973
99	GLUCOSE_DOWN_h	Peng_et_al_2002	H003000_01	Info	RAB5A, member RAS oncogene family	H003000_01	M28215	73957	RAB5A	Phosphoinositides and their downstream targets., Rab GTPases Mark Targets In The Endocytotic Machinery, The role of FYVE-finger proteins in vesicle transport, tsonc	0.0003278	0.591
100	GLUCOSE_DOWN_h	Peng_et_al_2002	H003112_01	Info	Retinoblastoma 1 (including osteosarcoma)	H003112_01	L41870	75770	RB1	BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc	0.0008596	0.674
101	GLUCOSE_DOWN_h	Peng_et_al_2002	H001800_01	Info	Proteasome (prosome, macropain) subunit, alpha type, 5	H001800_01	X61970	76913	PSMA5	Proteasome	0.00104	0.69
102	GLUCOSE_DOWN_h	Peng_et_al_2002	H003760_01	Info	DnaJ (Hsp40) homolog, subfamily A, member 1	H003760_01	L08069	94	DNAJA1		0.0016053	0.695
103	GLUCOSE_DOWN_h	Peng_et_al_2002	H007996_01	Info	GABA(A) receptor-associated protein	H007996_01	NM_007278	7719	GABARAP	Gamma-aminobutyric Acid Receptor Life Cycle	0.0021636	1.497
104	GLUCOSE_DOWN_h	Peng_et_al_2002	H001791_01	Info	Ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	H001791_01	X04741	76118	UCHL1		0.002493	0.711
105	GLUCOSE_DOWN_h	Peng_et_al_2002	H002387_01	Info	MutS (E. coli) homolog 2 (colon cancer, nonpolyposis type 1)	H002387_01	NM_000251	78934	MSH2	DNA_damage, tsonc	0.004273	0.694
106	GLUCOSE_DOWN_h	Peng_et_al_2002	H006293_01	Info	ATPase, H+ transporting, lysosomal (vacuolar proton pump) 21kD	H006293_01	D89052	7476	ATP6F	Perou's- Intrinsic- Breast-Cancer-Genes, ATP synthesis, Oxidative phosphorylation	0.0071282	1.372
107	GLUCOSE_DOWN_h	Peng_et_al_2002	H000152_01	Info	Kinesin-like 1	H000152_01	U37426	8878	KNSL1		0.0084868	0.761
108	GLUCOSE_DOWN_h	Peng_et_al_2002	H011911_01	Info	KIAA0594 protein	H011911_01	AB011166	103283	KIAA0594		0.0129673	1.228
109	GLUCOSE_DOWN_h	Peng_et_al_2002	H001903_01	Info	Polymerase (DNA directed), gamma	H001903_01	X98093	80961	POLG	DNA polymerase, Purine metabolism, Pyrimidine metabolism	0.0148856	0.783
110	GLUCOSE_DOWN_h	Peng_et_al_2002	H007126_01	Info	Mouse Mammary Turmor Virus Receptor homolog	H007126_01	AF052151	18686	MTVR		0.0175107	1.245
111	GLUCOSE_DOWN_h	Peng_et_al_2002	H003739_01	Info	Cell division cycle 2, G1 to S and G2 to M	H003739_01	X05360	184572	CDC2	Activation of Src by Protein-tyrosine phosphatase alpha, AKAP95 role in mitosis and chromosome dynamics, cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, How Progesterone Initiates the Oocyte Maturation, Protein Kinase A at the Centrosome, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of Splicing through Sam68, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, Stathmin and breast cancer resistance to antimicrotubule agents, Phosphatidylinositol signaling system, cell_cycle	0.0222229	0.733
112	GLUCOSE_DOWN_h	Peng_et_al_2002	H012105_01	Info	Testis enhanced gene transcript (BAX inhibitor 1)	H012105_01	X75861	74637	TEGT	transcription	0.0238861	1.237
113	GLUCOSE_DOWN_h	Peng_et_al_2002	H001391_01	Info	KIAA1093 protein	H001391_01	AB029016	117333	KIAA1093		0.0266235	1.238
114	GLUCOSE_DOWN_h	Peng_et_al_2002	H007917_01	Info	Translation factor sui1 homolog	H007917_01	NM_005875	21756	GC20		0.0373086	1.222
115	GLUCOSE_DOWN_h	Peng_et_al_2002	H001311_01	Info	ATP/GTP-binding protein	H001311_01	U73524	87465	HEAB		0.0452149	0.788
116	GLUCOSE_DOWN_h	Peng_et_al_2002	H003973_01	Info	EH domain containing 1	H003973_01	NM_006795	155119	EHD1		0.0507649	1.257
117	GLUCOSE_DOWN_h	Peng_et_al_2002	H000449_01	Info	Endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4	H000449_01	AF011466	122575	EDG4		0.0524489	1.347
118	GLUCOSE_DOWN_h	Peng_et_al_2002	H003719_01	Info	Integrin, beta 7	H003719_01	M68892	1741	ITGB7	cell_signaling, immunology, metastasis	0.0529984	0.815
119	GLUCOSE_DOWN_h	Peng_et_al_2002	H001798_01	Info	Ubiquitin specific protease 12	H001798_01	AF022789	42400	USP12		0.0549997	1.187
120	GLUCOSE_DOWN_h	Peng_et_al_2002	H000564_01	Info	Protein kinase C binding protein 1	H000564_01	AB032951	75871	PRKCBP1		0.0986503	0.835
121	GLUCOSE_DOWN_h	Peng_et_al_2002	H002491_01	Info	Bone morphogenetic protein 1	H002491_01	NM_006129	1274	BMP1	development	0.1079128	0.821
122	GLUCOSE_DOWN_h	Peng_et_al_2002	H002928_01	Info	CD47 antigen (Rh-related antigen, integrin-associated signal transducer)	H002928_01	X69398	82685	CD47	Perou's- Intrinsic- Breast-Cancer-Genes, angiogenesis, cell_signaling, immunology, metastasis	0.11106	0.854
123	GLUCOSE_DOWN_h	Peng_et_al_2002	H012158_01	Info	Upregulated by 1,25-dihydroxyvitamin D-3	H012158_01	S73591	179526	VDUP1		0.1293789	1.193
124	GLUCOSE_DOWN_h	Peng_et_al_2002	H003050_01	Info	Chaperonin containing TCP1, subunit 4 (delta)	H003050_01	AF026291	79150	CCT4	B Cell Survival Pathway	0.1325252	1.126
125	GLUCOSE_DOWN_h	Peng_et_al_2002	H001622_01	Info	RAB31, member RAS oncogene family	H001622_01	U59877	223025	RAB31	Perou's- Intrinsic- Breast-Cancer-Genes	0.152499	1.183
126	GLUCOSE_DOWN_h	Peng_et_al_2002	H002970_01	Info	Integrin-linked kinase	H002970_01	U40282	6196	ILK	PTEN dependent cell cycle arrest and apoptosis, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction	0.1701136	1.128
127	GLUCOSE_DOWN_h	Peng_et_al_2002	H002365_01	Info	Activated p21cdc42Hs kinase	H002365_01	L13738	153937	ACK1		0.173678	1.162
128	GLUCOSE_DOWN_h	Peng_et_al_2002	H000644_01	Info	Protein phosphatase 2, regulatory subunit B (B56), alpha isoform	H000644_01	L42373	155079	PPP2R5A	cell_cycle, cell_signaling, signal_transduction	0.1872145	0.884
129	GLUCOSE_DOWN_h	Peng_et_al_2002	H009793_01	Info	Rac/Cdc42 guanine exchange factor (GEF) 6	H009793_01	D25304	79307	ARHGEF6	Agrin in Postsynaptic Differentiation	0.2184793	1.139
130	GLUCOSE_DOWN_h	Peng_et_al_2002	H001256_01	Info	Sialyltransferase 4C (beta-galactosidase alpha-2,3-sialytransferase)	H001256_01	X74570	75268	SIAT4C		0.2276302	0.892
131	GLUCOSE_DOWN_h	Peng_et_al_2002	H009783_01	Info	KIAA0281 gene product	H009783_01	D87457	31463	KIAA0281		0.2322521	1.152
132	GLUCOSE_DOWN_h	Peng_et_al_2002	H002298_01	Info	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoinin	H002298_01	M30938	84981	XRCC5	Telomeres, Telomerase, Cellular Aging, and Immortality, DNA_damage, DNA_replication	0.2435454	1.101
133	GLUCOSE_DOWN_h	Peng_et_al_2002	H010810_01	Info	Splicing factor, arginine/serine-rich 1 (splicing factor 2, alternate splicing factor)	H010810_01	M72709	73737	SFRS1		0.2552533	0.909
134	GLUCOSE_DOWN_h	Peng_et_al_2002	H011501_01	Info	ADP-ribosylation factor 4	H011501_01	NM_001660	75290	ARF4		0.2579932	0.884
135	GLUCOSE_DOWN_h	Peng_et_al_2002	H001876_01	Info	3'-phosphoadenosine 5'-phosphosulfate synthase 1	H001876_01	AF105227	3833	PAPSS1	Purine metabolism, Selenoamino acid metabolism, Sulfur metabolism	0.2713835	0.89
136	GLUCOSE_DOWN_h	Peng_et_al_2002	H008985_01	Info	Eukaryotic translation initiation factor 3, subunit 3 (gamma, 40kD)	H008985_01	U54559	58189	EIF3S3		0.2852233	0.906
137	GLUCOSE_DOWN_h	Peng_et_al_2002	H001270_01	Info	Interferon, gamma-inducible protein 16	H001270_01	M63838	155530	IFI16	cell_signaling	0.2909837	1.116
138	GLUCOSE_DOWN_h	Peng_et_al_2002	H002973_01	Info	RAB1, member RAS oncogene family	H002973_01	M28209	3642	RAB1	Rab GTPases Mark Targets In The Endocytotic Machinery	0.292711	1.103
139	GLUCOSE_DOWN_h	Peng_et_al_2002	H003828_01	Info	Retinoblastoma-binding protein 4	H003828_01	X74262	16003	RBBP4	Mechanisms of transcriptional repression by DNA methylation, The PRC2 Complex Sets Long-term Gene Silencing Through Modification of Histone Tails	0.3028553	0.925
140	GLUCOSE_DOWN_h	Peng_et_al_2002	H002889_01	Info	Cyclin G1	H002889_01	X77794	79101	CCNG1		0.3030012	0.898
141	GLUCOSE_DOWN_h	Peng_et_al_2002	H003933_01	Info	General transcription factor IIA, 2 (12kD subunit)	H003933_01	U14193	76362	GTF2A2		0.3056055	0.899
142	GLUCOSE_DOWN_h	Peng_et_al_2002	H009033_01	Info	Neuromedin U	H009033_01	X76029	2841	NMU		0.3059932	1.152
143	GLUCOSE_DOWN_h	Peng_et_al_2002	H001344_01	Info	Fusion, derived from t(12;16) malignant liposarcoma	H001344_01	S62140	99969	FUS	misc	0.3107752	0.912
144	GLUCOSE_DOWN_h	Peng_et_al_2002	H012325_01	Info	Extra spindle poles, S. cerevisiae, homolog of	H012325_01	D79987	153479	KIAA0165		0.3223766	1.126
145	GLUCOSE_DOWN_h	Peng_et_al_2002	H008280_01	Info	Era (E. coli G-protein homolog)-like 1	H008280_01	AF082657	3426	ERAL1		0.326229	1.083
146	GLUCOSE_DOWN_h	Peng_et_al_2002	H001406_01	Info	Huntingtin interacting protein-1-related	H001406_01	AB014555	96731	KIAA0655		0.3265079	0.911
147	GLUCOSE_DOWN_h	Peng_et_al_2002	H000325_01	Info	Nuclear transcription factor Y, beta	H000325_01	X59710	84928	NFYB	Overview of telomerase RNA component gene hTerc Transcriptional Regulation	0.3282461	0.893
148	GLUCOSE_DOWN_h	Peng_et_al_2002	H002715_01	Info	Prohibitin	H002715_01	NM_002634	75323	PHB	immunology	0.3408704	0.898
149	GLUCOSE_DOWN_h	Peng_et_al_2002	H000723_01	Info	Angio-associated, migratory cell protein	H000723_01	M95627	83347	AAMP		0.3859087	0.934
150	GLUCOSE_DOWN_h	Peng_et_al_2002	H002782_01	Info	Wee1+ (S. pombe) homolog	H002782_01	X62048	75188	WEE1	cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G2/M Checkpoint, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, immunology	0.4033875	1.142
151	GLUCOSE_DOWN_h	Peng_et_al_2002	H012030_01	Info	Chromosome 1 open reading frame 8	H012030_01	AF047439	11441	C1ORF8		0.424321	0.929
152	GLUCOSE_DOWN_h	Peng_et_al_2002	H001314_01	Info	DEK oncogene (DNA binding)	H001314_01	X64229	110713	DEK		0.4424083	0.934
153	GLUCOSE_DOWN_h	Peng_et_al_2002	H008388_01	Info	Melanoma antigen, family D, 1	H008388_01	NM_006986	177556	MAGED1		0.4445493	0.9
154	GLUCOSE_DOWN_h	Peng_et_al_2002	H002127_01	Info	Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	H002127_01	D86550	75842	DYRK1A	Sonic Hedgehog (Shh) Pathway	0.4628734	0.926
155	GLUCOSE_DOWN_h	Peng_et_al_2002	H008179_01	Info	PTD017 protein	H008179_01	AL050361	274417	PTD017		0.5042695	1.068
156	GLUCOSE_DOWN_h	Peng_et_al_2002	H013411_01	Info	Ribosomal protein, large P2	H013411_01	M17887	119500	RPLP2		0.5256547	1.063
157	GLUCOSE_DOWN_h	Peng_et_al_2002	H010641_01	Info	Bromodomain adjacent to zinc finger domain, 1A	H010641_01	AB032252	8858	BAZ1A		0.5315479	1.065
158	GLUCOSE_DOWN_h	Peng_et_al_2002	H011767_01	Info	SH2-B homolog	H011767_01	AB037720	15744	DKFZP547G1110		0.5793807	1.053
159	GLUCOSE_DOWN_h	Peng_et_al_2002	H008484_01	Info	Heterogeneous nuclear ribonucleoprotein R	H008484_01	AF000364	15265	HNRPR		0.5936826	1.065
160	GLUCOSE_DOWN_h	Peng_et_al_2002	H001516_01	Info	Guanosine monophosphate reductase	H001516_01	M24470	1435	GMPR	Purine metabolism	0.5998588	0.932
161	GLUCOSE_DOWN_h	Peng_et_al_2002	H001288_01	Info	ELL gene (11-19 lysine-rich leukemia gene)	H001288_01	U16282	5881	ELL		0.6032943	1.082
162	GLUCOSE_DOWN_h	Peng_et_al_2002	H001304_01	Info	ALL1-fused gene from chromosome 1q	H001304_01	U16954	75823	AF1Q	Perou's- Intrinsic- Breast-Cancer-Genes	0.603919	1.053
163	GLUCOSE_DOWN_h	Peng_et_al_2002	H012106_01	Info	Src-like-adapter	H012106_01	D89077	75367	SLA		0.6044071	0.939
164	GLUCOSE_DOWN_h	Peng_et_al_2002	H002217_01	Info	Dishevelled 3 (homologous to Drosophila dsh)	H002217_01	NM_004423	174044	DVL3	cell_signaling, signal_transduction	0.6065023	1.058
165	GLUCOSE_DOWN_h	Peng_et_al_2002	H011167_01	Info	HSPC035 protein	H011167_01	NM_016127	279921	LOC51669		0.6199261	1.046
166	GLUCOSE_DOWN_h	Peng_et_al_2002	H011548_01	Info	Fzr1 protein	H011548_01	AB033068	268384	FZR1		0.6646964	1.035
167	GLUCOSE_DOWN_h	Peng_et_al_2002	H002527_01	Info	Replication protein A3 (14kD)	H002527_01	L07493	1608	RPA3	DNA_replication	0.6875779	0.952
168	GLUCOSE_DOWN_h	Peng_et_al_2002	H000388_01	Info	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6	H000388_01	AL110183	73851	ATP5J	ATP synthesis, Oxidative phosphorylation, misc	0.7600099	0.953
169	GLUCOSE_DOWN_h	Peng_et_al_2002	H010946_01	Info	Artemin	H010946_01	AF109401	194689	ARTN		0.7609159	1.05
170	GLUCOSE_DOWN_h	Peng_et_al_2002	H009706_01	Info	RAB1, member RAS oncogene family	H009706_01	AL050268	3642	RAB1	Rab GTPases Mark Targets In The Endocytotic Machinery	0.7686339	0.971
171	GLUCOSE_DOWN_h	Peng_et_al_2002	H003482_01	Info	Catechol-O-methyltransferase	H003482_01	NM_000754	240013	COMT	Tyrosine metabolism, behavior, immunology	0.777803	1.026
172	GLUCOSE_DOWN_h	Peng_et_al_2002	H011214_01	Info	Williams-Beuren syndrome chromosome region 1	H011214_01	D26068	180900	WBSCR1		0.7785992	0.975
173	GLUCOSE_DOWN_h	Peng_et_al_2002	H012850_01	Info	Nucleosome assembly protein 1-like 1	H012850_01	AL162068	179662	NAP1L1		0.7805775	0.973
174	GLUCOSE_DOWN_h	Peng_et_al_2002	H007376_01	Info	Homo sapiens cDNA: FLJ22071 fis, clone HEP11691	H007376_01	AL049932	326248			0.785212	1.026
175	GLUCOSE_DOWN_h	Peng_et_al_2002	H007641_01	Info	Solute carrier family 12 (potassium/chloride transporters), member 4	H007641_01	AF054506	10094	SLC12A4		0.7951601	1.026
176	GLUCOSE_DOWN_h	Peng_et_al_2002	H001333_01	Info	Phosphatidylinositol binding clathrin assembly protein	H001333_01	U45976	7885	PICALM	Endocytotic role of NDK, Phosphins and Dynamin	0.8121842	0.978
177	GLUCOSE_DOWN_h	Peng_et_al_2002	H008039_01	Info	DnaJ (Hsp40) homolog, subfamily B, member 6	H008039_01	AB015798	181195	DNAJB6	Prion Pathway	0.8136927	1.024
178	GLUCOSE_DOWN_h	Peng_et_al_2002	H008319_01	Info	KIAA0461 protein	H008319_01	AB007930	107088	KIAA0461		0.8286286	1.017
179	GLUCOSE_DOWN_h	Peng_et_al_2002	H003056_01	Info	FOS-like antigen 2	H003056_01	X16706	301612	FOSL2	Bone Remodelling, tsonc	0.85065	1.018
180	GLUCOSE_DOWN_h	Peng_et_al_2002	H012188_01	Info	E2F transcription factor 4, p107/p130-binding	H012188_01	S75174	108371	E2F4	METS affect on Macrophage Differentiation	0.8845118	0.986
181	GLUCOSE_DOWN_h	Peng_et_al_2002	H000641_01	Info	Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5	H000641_01	J02683	79172	SLC25A5		0.8966066	1.014
182	GLUCOSE_DOWN_h	Peng_et_al_2002	H012177_01	Info	SEC24 (S. cerevisiae) related gene family, member C	H012177_01	D38555	81964	SEC24C		0.9009444	0.987
183	GLUCOSE_DOWN_h	Peng_et_al_2002	H000555_01	Info	MAD2 (mitotic arrest deficient, yeast, homolog)-like 1	H000555_01	U65410	79078	MAD2L1	cell_cycle	0.9117596	1.012
184	GLUCOSE_DOWN_h	Peng_et_al_2002	H010542_01	Info	M-phase phosphoprotein homolog	H010542_01	NM_016107	173518	LOC51663		0.9533604	0.995
185	GLUCOSE_DOWN_h	Peng_et_al_2002	H001079_01	Info	Sodium channel, voltage-gated, type IV, alpha polypeptide	H001079_01	M81758	46038	SCN4A	immunology	0.9599901	1.005
186	GLUCOSE_DOWN_h	Peng_et_al_2002	H004613_01	Info	Telomeric repeat binding factor 2	H004613_01	AF002999	100030	TERF2	immunology	0.9802633	0.997
187	GLUCOSE_DOWN_h	Peng_et_al_2002	H002746_01	Info	TNF receptor-associated factor 5	H002746_01	AB000509	29736	TRAF5	TACI and BCMA stimulation of B cell immune responses., immunology	0.9871372	0.999
188	ghPathway_h	BioCarta	H000732_01	Info	Insulin receptor substrate 1	H000732_01	S62539	96063	IRS1	Perou's- Intrinsic- Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology	0.0013348	0.643
189	ghPathway_h	BioCarta	H002186_01	Info	Serum response factor (c-fos serum response element-binding transcription factor)	H002186_01	J03161	155321	SRF	EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription	0.0017465	0.722
190	ghPathway_h	BioCarta	H002055_01	Info	Growth factor receptor-bound protein 2	H002055_01	M96995	296381	GRB2	Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...	0.0022348	1.459
191	ghPathway_h	BioCarta	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
192	ghPathway_h	BioCarta	H002890_01	Info	Ribosomal protein S6 kinase, 90kD, polypeptide 1	H002890_01	L07597	149957	RPS6KA1	Cell Cycle: G2/M Checkpoint, Erk1/Erk2 Mapk Signaling pathway, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, MAPKinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Role of Erk5 in Neuronal Survival, Transcription factor CREB and its extracellular signals, Phosphatidylinositol signaling system	0.0138896	1.42
193	ghPathway_h	BioCarta	H001365_01	Info	Protein kinase C, beta 1	H001365_01	X07109	77202	PRKCB1	Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbal Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction	0.0304335	1.379
194	ghPathway_h	BioCarta	H003178_01	Info	Mitogen-activated protein kinase 3	H003178_01	X60188	861	MAPK3	Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...	0.0986041	1.184
195	ghPathway_h	BioCarta	H002624_01	Info	Insulin receptor	H002624_01	X02160	89695	INSR	Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Growth Hormone Signaling Pathway, Insulin Signaling Pathway, immunology	0.433218	0.919
196	ghPathway_h	BioCarta	H002261_01	Info	Signal transducer and activator of transcription 5B	H002261_01	U47686	244613	STAT5B		0.441402	1.071
197	ghPathway_h	BioCarta	H009068_01	Info	Homo sapiens mRNA; cDNA DKFZp586N1323 (from clone DKFZp586N1323)	H009068_01	AL080218	24064			0.509279	1.056
198	ghPathway_h	BioCarta	H002722_01	Info	Mitogen-activated protein kinase kinase 1	H002722_01	L11284	3446	MAP2K1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...	0.7377933	0.973
199	il2rbPathway_h	BioCarta	H000732_01	Info	Insulin receptor substrate 1	H000732_01	S62539	96063	IRS1	Perou's- Intrinsic- Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology	0.0013348	0.643
200	il2rbPathway_h	BioCarta	H000600_01	Info	STAT induced STAT inhibitor 3	H000600_01	AB004904	296176	SSI-3	IL-2 Receptor Beta Chain in T cell Activation, IL22 Soluble Receptor Signaling Pathway	0.0013931	0.69
201	il2rbPathway_h	BioCarta	H002055_01	Info	Growth factor receptor-bound protein 2	H002055_01	M96995	296381	GRB2	Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...	0.0022348	1.459
202	il2rbPathway_h	BioCarta	H000438_01	Info	CASP8 and FADD-like apoptosis regulator	H000438_01	Y14039	195175	CFLAR	FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, IL-2 Receptor Beta Chain in T cell Activation, Induction of apoptosis through DR3 and DR4/5 Death Receptors	0.00266	1.745
203	il2rbPathway_h	BioCarta	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
204	il2rbPathway_h	BioCarta	H003332_01	Info	V-crk avian sarcoma virus CT10 oncogene homolog-like	H003332_01	X59656	37078	CRKL	IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, Signaling of Hepatocyte Growth Factor Receptor, tsonc	0.0164206	0.675
205	il2rbPathway_h	BioCarta	H003305_01	Info	Ribosomal protein S6 kinase, 70kD, polypeptide 1	H003305_01	M60724	86858	RPS6KB1	CTCF: First Multivalent Nuclear Factor, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, MAPKinase Signaling Pathway, mTOR Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Rac 1 cell motility signaling pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction	0.0214523	1.448
206	il2rbPathway_h	BioCarta	H003718_01	Info	Interleukin 2 receptor, gamma (severe combined immunodeficiency)	H003718_01	D11086	84	IL2RG	IL 2 signaling pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, immunology	0.0314631	1.258
207	il2rbPathway_h	BioCarta	H013244_01	Info	N-myc (and STAT) interactor	H013244_01	U32849	54483	NMI	IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, signal_transduction	0.0799702	1.269
208	il2rbPathway_h	BioCarta	H003178_01	Info	Mitogen-activated protein kinase 3	H003178_01	X60188	861	MAPK3	Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...	0.0986041	1.184
209	il2rbPathway_h	BioCarta	H014546_01	Info	Peptidylprolyl isomerase A (cyclophilin A)	H014546_01	NM_021130	182937	PPIA	IL-2 Receptor Beta Chain in T cell Activation	0.129858	1.176
210	il2rbPathway_h	BioCarta	H002091_01	Info	V-myc avian myelocytomatosis viral oncogene homolog	H002091_01	K02276	79070	MYC	Cadmium induces DNA synthesis and proliferation in macrophages, CTCF: First Multivalent Nuclear Factor, Erk1/Erk2 Mapk Signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, MAPKinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, WNT Signaling Pathway, gene_regulation, immunology, transcription, tsonc	0.1797519	0.824
211	il2rbPathway_h	BioCarta	H003042_01	Info	BCL2-like 1	H003042_01	Z23115	305890	BCL2L1	Apoptotic Signaling in Response to DNA Damage, IL-2 Receptor Beta Chain in T cell Activation, Opposing roles of AIF in Apoptosis and Cell Survival, Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, immunology	0.2336065	1.143
212	il2rbPathway_h	BioCarta	H001349_01	Info	Janus kinase 1 (a protein tyrosine kinase)	H001349_01	M64174	50651	JAK1	EGF Signaling Pathway, IFN alpha signaling pathway, IFN gamma signaling pathway , IL 2 signaling pathway, IL 4 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, PDGF Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction	0.2754104	1.129
213	il2rbPathway_h	BioCarta	H002261_01	Info	Signal transducer and activator of transcription 5B	H002261_01	U47686	244613	STAT5B		0.441402	1.071
214	il2rbPathway_h	BioCarta	H003644_01	Info	Tumor necrosis factor receptor superfamily, member 6	H003644_01	X63717	82359	TNFRSF6	apoptosis, immunology	0.4621499	0.927
215	il2rbPathway_h	BioCarta	H002824_01	Info	Janus kinase 3 (a protein tyrosine kinase, leukocyte)	H002824_01	U09607	99877	JAK3	IL 2 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, IL22 Soluble Receptor Signaling Pathway , IL-7 Signal Transduction, Stat3 Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction	0.4735774	1.051
216	il2rbPathway_h	BioCarta	H009068_01	Info	Homo sapiens mRNA; cDNA DKFZp586N1323 (from clone DKFZp586N1323)	H009068_01	AL080218	24064			0.509279	1.056
217	il2rbPathway_h	BioCarta	H003650_01	Info	Interleukin 2 receptor, alpha	H003650_01	X01057	1724	IL2RA	IL 2 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Role of Tob in T-cell activation, Th1/Th2 Differentiation, immunology	0.5932248	1.054
218	il2rbPathway_h	BioCarta	H003612_01	Info	V-akt murine thymoma viral oncogene homolog 1	H003612_01	M63167	71816	AKT1	Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signalling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation ...	0.6741257	1.038
219	il2rbPathway_h	BioCarta	H001974_01	Info	BCL2-antagonist of cell death	H001974_01	U66879	76366	BAD	AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phosphoinositides and their downstream targets., Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Trefoil Factors Initiate Mucosal Healing, apoptosis, development	0.6985187	0.954
220	il2rbPathway_h	BioCarta	H015889_01	Info	BCL2-like 1	H015889_01	NM_001191	305890	BCL2L1	Apoptotic Signaling in Response to DNA Damage, IL-2 Receptor Beta Chain in T cell Activation, Opposing roles of AIF in Apoptosis and Cell Survival, Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, immunology	0.996743	1.001
221	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	H001032_01	Info	Cytotoxic T-lymphocyte-associated protein 4	H001032_01	L15006	247824	CTLA4	The Co-Stimulatory Signal During T-cell Activation, immunology	0.0001134	0.56
222	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	H008261_01	Info	RAS guanyl releasing protein 2 (calcium and DAG-regulated)	H008261_01	Y12336	99491	RASGRP2		0.0002126	1.594
223	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	H002055_01	Info	Growth factor receptor-bound protein 2	H002055_01	M96995	296381	GRB2	Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...	0.0022348	1.459
224	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
225	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	H003628_01	Info	Dystroglycan 1 (dystrophin-associated glycoprotein 1)	H003628_01	L19711	76111	DAG1	Agrin in Postsynaptic Differentiation, immunology	0.034627	0.774
226	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	H003212_01	Info	Zeta-chain (TCR) associated protein kinase (70 kD)	H003212_01	L05148	234569	ZAP70	Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, Lck and Fyn tyrosine kinases in initiation of TCR Activation, T Cell Receptor Signaling Pathway, cell_cycle, cell_signaling, signal_transduction	0.0970422	0.833
227	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	H002287_01	Info	P21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related)	H002287_01	U24152	62402	PAK1	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, FAS signaling pathway ( CD95 ), fMLP induced chemokine gene expression in HMC-1 cells, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Rac 1 cell motility signaling pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, TNFR1 Signaling Pathway	0.1104284	0.815
228	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	H001748_01	Info	Inositol 1,4,5-trisphosphate 3-kinase B	H001748_01	X57206	78877	ITPKB	Inositol phosphate metabolism, Phosphatidylinositol signaling system, cell_signaling, signal_transduction	0.1283627	0.851
229	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	H001718_01	Info	Inositol 1,4,5-trisphosphate 3-kinase A	H001718_01	X54938	2722	ITPKA	Inositol phosphate metabolism, Phosphatidylinositol signaling system	0.1331494	1.16
230	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	H003550_01	Info	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	H003550_01	S76638	73090	NFKB2	gene_regulation, immunology, transcription, tsonc	0.1593331	1.165
231	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	H011731_01	Info	P21 (CDKN1A)-activated kinase 3	H011731_01	AF068864	152663	PAK3	Phosphatidylinositol signaling system	0.1960548	1.141
232	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	H003820_01	Info	Lymphocyte-specific protein tyrosine kinase	H003820_01	X05027	1765	LCK	Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, IL 2 signaling pathway, IL-7 Signal Transduction, Lck and Fyn tyrosine kinases in initiation of TCR Activation, T Cell Receptor Signaling Pathway, The Co-Stimulatory Signal During T-cell Activation, immunology, signal_transduction, tsonc	0.2266863	0.873
233	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	H000543_01	Info	Linker for activation of T cells	H000543_01	AJ223280	83496	LAT	Ras-Independent pathway in NK cell-mediated cytotoxicity, T Cell Receptor Signaling Pathway	0.354745	0.903
234	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	H013901_01	Info	Protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs	H013901_01	AB032968	20447	PAK4	Phosphatidylinositol signaling system	0.3636917	0.913
235	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	H012554_01	Info	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	H012554_01	AF081195	182591	RASGRP1		0.3661482	0.901
236	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	H015286_01	Info	Homo sapiens PAK2 mRNA, complete cds	H015286_01	AF092132	284275		FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, MAPKinase Signaling Pathway, TNFR1 Signaling Pathway, Phosphatidylinositol signaling system	0.4868167	1.068
237	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	H008413_01	Info	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1	H008413_01	X77909	2764	NFKBIL1		0.5281661	1.058
238	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	H002812_01	Info	Protein tyrosine phosphatase, receptor type, C	H002812_01	Y00062	170121	PTPRC	Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, B Lymphocyte Cell Surface Molecules, Lck and Fyn tyrosine kinases in initiation of TCR Activation, T Cytotoxic Cell Surface Molecules, T Helper Cell Surface Molecules, cell_cycle, cell_signaling, immunology	0.6066202	1.093
239	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	H003651_01	Info	EphB2	H003651_01	AF025304	125124	EPHB2	development	0.7855294	0.971
240	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	H002447_01	Info	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	H002447_01	M69043	81328	NFKBIA	Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAPKinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, T Cell Receptor Signaling Pathway, The 4-1BB-dependent immune respon ...	0.8245205	0.975
241	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	H012662_01	Info	Homo sapiens cDNA FLJ10205 fis, clone HEMBA1004954	H012662_01	AK001067	6226			0.8484663	1.017
242	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	H003711_01	Info	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)	H003711_01	M58603	83428	NFKB1	Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAPKinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a ...	0.8665095	1.017
243	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	H001340_01	Info	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD)	H001340_01	U20158	2488	LCP2	immunology	0.9191876	1.009
244	ST_T_Cell_Signal_Transduction_h	Signalling Transduction KE	H003340_01	Info	C-src tyrosine kinase	H003340_01	X60114	77793	CSK	Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, Activation of Src by Protein-tyrosine phosphatase alpha, Cell to Cell Adhesion Signaling, Integrin Signaling Pathway, signal_transduction	0.9390319	1.008
245	pdgfPathway_h	BioCarta	H002186_01	Info	Serum response factor (c-fos serum response element-binding transcription factor)	H002186_01	J03161	155321	SRF	EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription	0.0017465	0.722
246	pdgfPathway_h	BioCarta	H002055_01	Info	Growth factor receptor-bound protein 2	H002055_01	M96995	296381	GRB2	Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...	0.0022348	1.459
247	pdgfPathway_h	BioCarta	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
248	pdgfPathway_h	BioCarta	H003611_01	Info	Mitogen-activated protein kinase kinase 4	H003611_01	L36870	75217	MAP2K4	Perou's- Intrinsic- Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system	0.012502	0.753
249	pdgfPathway_h	BioCarta	H001365_01	Info	Protein kinase C, beta 1	H001365_01	X07109	77202	PRKCB1	Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbal Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction	0.0304335	1.379
250	pdgfPathway_h	BioCarta	H003178_01	Info	Mitogen-activated protein kinase 3	H003178_01	X60188	861	MAPK3	Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...	0.0986041	1.184
251	pdgfPathway_h	BioCarta	H001600_01	Info	RAS p21 protein activator (GTPase activating protein) 1	H001600_01	M23379	758	RASA1	EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction	0.1015906	0.844
252	pdgfPathway_h	BioCarta	H003158_01	Info	Mitogen-activated protein kinase 8	H003158_01	L26318	190913	MAPK8	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...	0.1287835	1.166
253	pdgfPathway_h	BioCarta	H002775_01	Info	Platelet-derived growth factor receptor, alpha polypeptide	H002775_01	M21574	74615	PDGFRA	Perou's- Intrinsic- Breast-Cancer-Genes, CBL mediated ligand-induced downregulation of EGF receptors, Erk1/Erk2 Mapk Signaling pathway, PDGF Signaling Pathway, Phospholipids as signalling intermediaries, Rac 1 cell motility signaling pathway, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, immunology, signal_transduction	0.1636921	1.107
254	pdgfPathway_h	BioCarta	H001349_01	Info	Janus kinase 1 (a protein tyrosine kinase)	H001349_01	M64174	50651	JAK1	EGF Signaling Pathway, IFN alpha signaling pathway, IFN gamma signaling pathway , IL 2 signaling pathway, IL 4 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, PDGF Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction	0.2754104	1.129
255	pdgfPathway_h	BioCarta	H003231_01	Info	Platelet-derived growth factor alpha polypeptide	H003231_01	X06374	37040	PDGFA	Cytokines and Inflammatory Response, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), PDGF Signaling Pathway, Phospholipids as signalling intermediaries, immunology, misc, signal_transduction	0.6989894	1.039
256	pdgfPathway_h	BioCarta	H002722_01	Info	Mitogen-activated protein kinase kinase 1	H002722_01	L11284	3446	MAP2K1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...	0.7377933	0.973
257	igf1rPathway_h	BioCarta	H000732_01	Info	Insulin receptor substrate 1	H000732_01	S62539	96063	IRS1	Perou's- Intrinsic- Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology	0.0013348	0.643
258	igf1rPathway_h	BioCarta	H002055_01	Info	Growth factor receptor-bound protein 2	H002055_01	M96995	296381	GRB2	Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...	0.0022348	1.459
259	igf1rPathway_h	BioCarta	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
260	igf1rPathway_h	BioCarta	H002473_01	Info	Insulin-like growth factor 1 receptor	H002473_01	NM_000875	239176	IGF1R	Perou's- Intrinsic- Breast-Cancer-Genes, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Erk1/Erk2 Mapk Signaling pathway, IGF-1 Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Telomeres, Telomerase, Cellular Aging, and Immortality, The IGF-1 Receptor and Longevity, immunology	0.079692	1.158
261	igf1rPathway_h	BioCarta	H003178_01	Info	Mitogen-activated protein kinase 3	H003178_01	X60188	861	MAPK3	Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...	0.0986041	1.184
262	igf1rPathway_h	BioCarta	H003612_01	Info	V-akt murine thymoma viral oncogene homolog 1	H003612_01	M63167	71816	AKT1	Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signalling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation ...	0.6741257	1.038
263	igf1rPathway_h	BioCarta	H001974_01	Info	BCL2-antagonist of cell death	H001974_01	U66879	76366	BAD	AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phosphoinositides and their downstream targets., Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Trefoil Factors Initiate Mucosal Healing, apoptosis, development	0.6985187	0.954
264	igf1rPathway_h	BioCarta	H002722_01	Info	Mitogen-activated protein kinase kinase 1	H002722_01	L11284	3446	MAP2K1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...	0.7377933	0.973
265	MAPK_Cascade_h	GO	H003200_01	Info	Mitogen-activated protein kinase kinase 3	H003200_01	D87116	180533	MAP2K3	fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway	0.0009666	1.561
266	MAPK_Cascade_h	GO	H001648_01	Info	Myelin basic protein	H001648_01	M13577	69547	MBP		0.0014651	0.667
267	MAPK_Cascade_h	GO	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
268	MAPK_Cascade_h	GO	H002895_01	Info	Mitogen-activated protein kinase 14	H002895_01	L35263	79107	MAPK14	BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAPKinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm ...	0.0086925	1.429
269	MAPK_Cascade_h	GO	H003611_01	Info	Mitogen-activated protein kinase kinase 4	H003611_01	L36870	75217	MAP2K4	Perou's- Intrinsic- Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system	0.012502	0.753
270	MAPK_Cascade_h	GO	H003178_01	Info	Mitogen-activated protein kinase 3	H003178_01	X60188	861	MAPK3	Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...	0.0986041	1.184
271	MAPK_Cascade_h	GO	H000029_01	Info	Mitogen-activated protein kinase kinase kinase 3	H000029_01	U78876	29282	MAP3K3	MAPKinase Signaling Pathway, Phosphatidylinositol signaling system	0.2027051	1.138
272	MAPK_Cascade_h	GO	H002943_01	Info	V-raf murine sarcoma viral oncogene homolog B1	H002943_01	M95712	622	BRAF	MAPKinase Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction, tsonc	0.2376595	0.895
273	MAPK_Cascade_h	GO	H003309_01	Info	Mitogen-activated protein kinase kinase 7	H003309_01	AF013589	110299	MAP2K7	Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAPKinase Signaling Pathway	0.3044184	1.088
274	MAPK_Cascade_h	GO	H002722_01	Info	Mitogen-activated protein kinase kinase 1	H002722_01	L11284	3446	MAP2K1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...	0.7377933	0.973
275	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H002038_01	Info	Flavin containing monooxygenase 5	H002038_01	Z47553	14286	FMO5	Perou's- Intrinsic- Breast-Cancer-Genes	0.0001007	1.877
276	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H003352_01	Info	Interleukin 1 receptor, type I	H003352_01	M27492	82112	IL1R1	NF-kB Signaling Pathway, Signal transduction through IL1R, immunology	0.000502	0.677
277	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H000872_01	Info	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	H000872_01	AF104942	108660	ABCC5		0.00423	0.773
278	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H015306_01	Info	Core promoter element binding protein	H015306_01	NM_001300	285313	COPEB		0.0052134	1.473
279	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H000896_01	Info	Stanniocalcin 1	H000896_01	U25997	25590	STC1		0.0071618	0.726
280	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H001508_01	Info	Aldehyde dehydrogenase 4 family, member A1	H001508_01	U24266	77448	ALDH4A1	Catabolic Pathways for Arginine , Histidine, Glutamate, Glutamine, and Proline, Arginine and proline metabolism, Glutamate metabolism	0.0262657	0.769
281	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H002243_01	Info	Ras homolog gene family, member E	H002243_01	S82240	6838	ARHE	immunology	0.032366	1.421
282	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H003570_01	Info	Annexin A3	H003570_01	M20560	1378	ANXA3		0.049571	1.236
283	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H002515_01	Info	Clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed pro	H002515_01	M25915	75106	CLU	Perou's- Intrinsic- Breast-Cancer-Genes, immunology	0.0769494	0.829
284	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H001717_01	Info	RAP1, GTPase activating protein 1	H001717_01	M64788	75151	RAP1GA1		0.0888214	1.197
285	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H015322_01	Info	CD24 antigen (small cell lung carcinoma cluster 4 antigen)	H015322_01	NM_013230	286124	CD24	Perou's- Intrinsic- Breast-Cancer-Genes	0.0961671	1.127
286	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H007609_01	Info	Protein phosphatase 1, regulatory (inhibitor) subunit 5	H007609_01	Y18207	303090	PPP1R5		0.1045358	1.172
287	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H015668_01	Info	Parvalbumin	H015668_01	NM_002854	295449	PVALB		0.153268	0.857
288	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H009511_01	Info	Melanoma associated gene	H009511_01	D86983	118893	D2S448		0.1767501	0.81
289	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H008648_01	Info	Selenium binding protein 1	H008648_01	U29091	288973	SELENBP1	Perou's- Intrinsic- Breast-Cancer-Genes	0.2017613	1.203
290	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H001905_01	Info	LPS-induced TNF-alpha factor	H001905_01	NM_004862	76507	PIG7		0.2026162	1.209
291	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H003391_01	Info	Laminin, beta 1	H003391_01	NM_002291	82124	LAMB1	Prion Pathway	0.2163833	0.846
292	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H000262_01	Info	KIAA0307 gene product	H000262_01	AB002305	6111	KIAA0307		0.2604448	0.889
293	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H007445_01	Info	Homo sapiens cDNA FLJ20153 fis, clone COL08656, highly similar to AJ001381 Homo sapiens incomplete c	H007445_01	AK000160	121576			0.2652388	0.847
294	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H000651_01	Info	Mad4 homolog	H000651_01	AF040963	102402	MAD4		0.266447	0.891
295	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H000502_01	Info	Phosphoribosyl pyrophosphate synthetase 1	H000502_01	D00860	56	PRPS1	Histidine metabolism, Pentose phosphate pathway, Purine metabolism, gene_regulation, transcription	0.3045664	0.909
296	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H008715_01	Info	ATP-binding cassette, sub-family G (WHITE), member 1	H008715_01	X91249	10237	ABCG1	Nuclear Receptors in Lipid Metabolism and Toxicity	0.4098523	1.096
297	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H003763_01	Info	Folate hydrolase (prostate-specific membrane antigen) 1	H003763_01	M99487	1915	FOLH1		0.4171314	0.905
298	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H013236_01	Info	Monocyte to macrophage differentiation-associated	H013236_01	X85750	79889	MMD		0.4241064	0.921
299	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H003935_01	Info	KIAA0922 protein	H003935_01	AB023139	37892	KIAA0922		0.4306564	1.134
300	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H003371_01	Info	Erythropoietin receptor	H003371_01	NM_000121	89548	EPOR	Perou's- Intrinsic- Breast-Cancer-Genes, EPO Signaling Pathway, Erythropoietin mediated neuroprotection through NF-kB, immunology	0.4485722	0.93
301	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H005832_01	Info	Kynureninase (L-kynurenine hydrolase)	H005832_01	U57721	169139	KYNU	Tryptophan metabolism	0.5223633	1.074
302	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H011966_01	Info	Syntaxin binding protein 1	H011966_01	AF004563	239356	STXBP1		0.5388587	1.065
303	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H004814_01	Info	N-myc downstream regulated	H004814_01	D87953	75789	NDRG1		0.5742952	1.047
304	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H003024_01	Info	Cathepsin H	H003024_01	X16832	288181	CTSH	Perou's- Intrinsic- Breast-Cancer-Genes	0.5964026	1.048
305	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H001606_01	Info	Drebrin 1	H001606_01	AL110225	89434	DBN1		0.6301138	1.048
306	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H013890_01	Info	Slit (Drosophila) homolog 2	H013890_01	AF055585	29802	SLIT2		0.696259	0.965
307	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H000900_01	Info	Matrilin 2	H000900_01	AL137638	19368	MATN2		0.7034604	0.949
308	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H003542_01	Info	V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene	H003542_01	M11730	323910	ERBB2	Perou's- Intrinsic- Breast-Cancer-Genes, Role of ERBB2 in Signal Transduction and Oncology, Trefoil Factors Initiate Mucosal Healing, immunology, signal_transduction, tsonc	0.7160857	1.031
309	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H003155_01	Info	CD24 antigen (small cell lung carcinoma cluster 4 antigen)	H003155_01	L33930	286124	CD24	Perou's- Intrinsic- Breast-Cancer-Genes	0.7363586	0.966
310	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H003434_01	Info	Dual specificity phosphatase 1	H003434_01	NM_004417	171695	DUSP1	CD40L Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, TNFR2 Signaling Pathway	0.8183145	0.968
311	FRASOR_ER_DOWN_h	Frasor_et_al_2004	H001715_01	Info	Dual specificity phosphatase 4	H001715_01	AL137704	2359	DUSP4	Perou's- Intrinsic- Breast-Cancer-Genes, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, cell_cycle, cell_signaling	0.9634643	1.004
312	SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h	SignallingAlliance	H000732_01	Info	Insulin receptor substrate 1	H000732_01	S62539	96063	IRS1	Perou's- Intrinsic- Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology	0.0013348	0.643
313	SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h	SignallingAlliance	H002055_01	Info	Growth factor receptor-bound protein 2	H002055_01	M96995	296381	GRB2	Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...	0.0022348	1.459
314	SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h	SignallingAlliance	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
315	SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h	SignallingAlliance	H001348_01	Info	Phosphoinositide-3-kinase, catalytic, delta polypeptide	H001348_01	U86453	162808	PIK3CD	Inositol phosphate metabolism, Phosphatidylinositol signaling system	0.0324563	1.426
316	SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h	SignallingAlliance	H016134_01	Info	V-akt murine thymoma viral oncogene homolog 2	H016134_01	NM_001626	326445	AKT2	Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc	0.0530988	1.287
317	SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h	SignallingAlliance	H003178_01	Info	Mitogen-activated protein kinase 3	H003178_01	X60188	861	MAPK3	Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...	0.0986041	1.184
318	SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h	SignallingAlliance	H001349_01	Info	Janus kinase 1 (a protein tyrosine kinase)	H001349_01	M64174	50651	JAK1	EGF Signaling Pathway, IFN alpha signaling pathway, IFN gamma signaling pathway , IL 2 signaling pathway, IL 4 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, PDGF Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction	0.2754104	1.129
319	SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h	SignallingAlliance	H003497_01	Info	V-akt murine thymoma viral oncogene homolog 2	H003497_01	M77198	326445	AKT2	Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc	0.3314111	0.872
320	SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h	SignallingAlliance	H000650_01	Info	Glycogen synthase kinase 3 beta	H000650_01	L33801	78802	GSK3B	ALK in cardiac myocytes, Cell Cycle: G1/S Check Point , Deregulation of CDK5 in Alzheimers Disease, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Presenilin action in Notch and Wnt signaling, Regulation of eIF2, Segmentation Clock, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Sonic Hedgehog (Shh) Pathway, WNT Signaling Pathway, Phosphatidylinositol signaling system	0.353328	1.118
321	SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h	SignallingAlliance	H002824_01	Info	Janus kinase 3 (a protein tyrosine kinase, leukocyte)	H002824_01	U09607	99877	JAK3	IL 2 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, IL22 Soluble Receptor Signaling Pathway , IL-7 Signal Transduction, Stat3 Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction	0.4735774	1.051
322	SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h	SignallingAlliance	H002236_01	Info	Mitogen-activated protein kinase kinase kinase kinase 1	H002236_01	U66464	86575	MAP4K1	MAPKinase Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor, Phosphatidylinositol signaling system	0.5747172	0.927
323	SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h	SignallingAlliance	H003612_01	Info	V-akt murine thymoma viral oncogene homolog 1	H003612_01	M63167	71816	AKT1	Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signalling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation ...	0.6741257	1.038
324	SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h	SignallingAlliance	H001974_01	Info	BCL2-antagonist of cell death	H001974_01	U66879	76366	BAD	AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phosphoinositides and their downstream targets., Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Trefoil Factors Initiate Mucosal Healing, apoptosis, development	0.6985187	0.954
325	mapkPathway_h	BioCarta	H003200_01	Info	Mitogen-activated protein kinase kinase 3	H003200_01	D87116	180533	MAP2K3	fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway	0.0009666	1.561
326	mapkPathway_h	BioCarta	H002055_01	Info	Growth factor receptor-bound protein 2	H002055_01	M96995	296381	GRB2	Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...	0.0022348	1.459
327	mapkPathway_h	BioCarta	H003232_01	Info	Mitogen-activated protein kinase kinase kinase 14	H003232_01	Y10256	47007	MAP3K14	CD40L Signaling Pathway, Double Stranded RNA Induced Gene Expression, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Keratinocyte Differentiation, MAPKinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, TACI and BCMA stimulation of B cell immune responses., TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system	0.005309	0.755
328	mapkPathway_h	BioCarta	H002763_01	Info	Mitogen-activated protein kinase kinase kinase 8	H002763_01	D14497	248	MAP3K8	MAPKinase Signaling Pathway	0.005954	1.333
329	mapkPathway_h	BioCarta	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
330	mapkPathway_h	BioCarta	H002895_01	Info	Mitogen-activated protein kinase 14	H002895_01	L35263	79107	MAPK14	BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAPKinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm ...	0.0086925	1.429
331	mapkPathway_h	BioCarta	H002320_01	Info	Ribosomal protein S6 kinase, 70kD, polypeptide 2	H002320_01	AB016869	103081	RPS6KB2	MAPKinase Signaling Pathway	0.0093261	0.755
332	mapkPathway_h	BioCarta	H004176_01	Info	Mitogen-activated protein kinase kinase kinase 11	H004176_01	L32976	89449	MAP3K11	MAPKinase Signaling Pathway	0.0101996	1.263
333	mapkPathway_h	BioCarta	H003611_01	Info	Mitogen-activated protein kinase kinase 4	H003611_01	L36870	75217	MAP2K4	Perou's- Intrinsic- Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system	0.012502	0.753
334	mapkPathway_h	BioCarta	H003008_01	Info	Mitogen-activated protein kinase kinase kinase 4	H003008_01	AF002715	32353	MAP3K4	MAPKinase Signaling Pathway, Phosphatidylinositol signaling system	0.0127738	0.707
335	mapkPathway_h	BioCarta	H002890_01	Info	Ribosomal protein S6 kinase, 90kD, polypeptide 1	H002890_01	L07597	149957	RPS6KA1	Cell Cycle: G2/M Checkpoint, Erk1/Erk2 Mapk Signaling pathway, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, MAPKinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Role of Erk5 in Neuronal Survival, Transcription factor CREB and its extracellular signals, Phosphatidylinositol signaling system	0.0138896	1.42
336	mapkPathway_h	BioCarta	H003493_01	Info	MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B)	H003493_01	X63380	78881	MEF2B		0.0145042	1.328
337	mapkPathway_h	BioCarta	H001992_01	Info	Activating transcription factor 2	H001992_01	X15875	198166	ATF2	ALK in cardiac myocytes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , The 4-1BB-dependent immune response, The information-processing pathway at the IFN-beta enhancer	0.0178377	0.749
338	mapkPathway_h	BioCarta	H003305_01	Info	Ribosomal protein S6 kinase, 70kD, polypeptide 1	H003305_01	M60724	86858	RPS6KB1	CTCF: First Multivalent Nuclear Factor, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, MAPKinase Signaling Pathway, mTOR Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Rac 1 cell motility signaling pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction	0.0214523	1.448
339	mapkPathway_h	BioCarta	H000612_01	Info	Ribosomal protein S6 kinase, 90kD, polypeptide 3	H000612_01	U08316	173965	RPS6KA3	MAPKinase Signaling Pathway, Signaling Pathway from G-Protein Families, Phosphatidylinositol signaling system	0.0473043	0.79
340	mapkPathway_h	BioCarta	H003259_01	Info	Sp1 transcription factor	H003259_01	J03133	2021	SP1	Agrin in Postsynaptic Differentiation, Effects of calcineurin in Keratinocyte Differentiation, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, MAPKinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase protein component gene hTert Transcriptional Regulation , Overview of telomerase RNA component gene hTerc Transcriptional Regulation	0.0557417	0.814
341	mapkPathway_h	BioCarta	H011228_01	Info	G protein-coupled receptor kinase 7	H011228_01	AL137615	261828	GPRK7	Perou's- Intrinsic- Breast-Cancer-Genes, Erk1/Erk2 Mapk Signaling pathway, MAPKinase Signaling Pathway, Phosphatidylinositol signaling system	0.0572981	1.27
342	mapkPathway_h	BioCarta	H000521_01	Info	Ribosomal protein S6 kinase, 90kD, polypeptide 2	H000521_01	X85106	301664	RPS6KA2	MAPKinase Signaling Pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction	0.0604408	1.207
343	mapkPathway_h	BioCarta	H002588_01	Info	Mitogen-activated protein kinase 7	H002588_01	U29725	3080	MAPK7	Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), MAPKinase Signaling Pathway, Role of Erk5 in Neuronal Survival, Phosphatidylinositol signaling system	0.0614441	0.811
344	mapkPathway_h	BioCarta	H009683_01	Info	Mitogen-activated protein kinase kinase kinase kinase 4	H009683_01	AB014587	3628	MAP4K4	MAPKinase Signaling Pathway, Phosphatidylinositol signaling system	0.0707782	1.203
345	mapkPathway_h	BioCarta	H003107_01	Info	Mitogen-activated protein kinase 13	H003107_01	AF004709	178695	MAPK13	Keratinocyte Differentiation, MAPKinase Signaling Pathway, Stathmin and breast cancer resistance to antimicrotubule agents, Phosphatidylinositol signaling system	0.0717244	1.171
346	mapkPathway_h	BioCarta	H002049_01	Info	Death-associated protein 6	H002049_01	AB015051	180224	DAXX	FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , Regulation of transcriptional activity by PML, Stress Induction of HSP Regulation, apoptosis	0.0788021	1.159
347	mapkPathway_h	BioCarta	H003178_01	Info	Mitogen-activated protein kinase 3	H003178_01	X60188	861	MAPK3	Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...	0.0986041	1.184
348	mapkPathway_h	BioCarta	H002287_01	Info	P21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related)	H002287_01	U24152	62402	PAK1	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, FAS signaling pathway ( CD95 ), fMLP induced chemokine gene expression in HMC-1 cells, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Rac 1 cell motility signaling pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, TNFR1 Signaling Pathway	0.1104284	0.815
349	mapkPathway_h	BioCarta	H003158_01	Info	Mitogen-activated protein kinase 8	H003158_01	L26318	190913	MAPK8	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...	0.1287835	1.166
350	mapkPathway_h	BioCarta	H002091_01	Info	V-myc avian myelocytomatosis viral oncogene homolog	H002091_01	K02276	79070	MYC	Cadmium induces DNA synthesis and proliferation in macrophages, CTCF: First Multivalent Nuclear Factor, Erk1/Erk2 Mapk Signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, MAPKinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, WNT Signaling Pathway, gene_regulation, immunology, transcription, tsonc	0.1797519	0.824
351	mapkPathway_h	BioCarta	H002501_01	Info	Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	H002501_01	D25274	173737	RAC1	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signalling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments	0.1980127	1.118
352	mapkPathway_h	BioCarta	H000029_01	Info	Mitogen-activated protein kinase kinase kinase 3	H000029_01	U78876	29282	MAP3K3	MAPKinase Signaling Pathway, Phosphatidylinositol signaling system	0.2027051	1.138
353	mapkPathway_h	BioCarta	H002943_01	Info	V-raf murine sarcoma viral oncogene homolog B1	H002943_01	M95712	622	BRAF	MAPKinase Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction, tsonc	0.2376595	0.895
354	mapkPathway_h	BioCarta	H003309_01	Info	Mitogen-activated protein kinase kinase 7	H003309_01	AF013589	110299	MAP2K7	Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAPKinase Signaling Pathway	0.3044184	1.088
355	mapkPathway_h	BioCarta	H002405_01	Info	Mitogen-activated protein kinase kinase 2	H002405_01	L11285	72241	MAP2K2	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor	0.3118803	1.093
356	mapkPathway_h	BioCarta	H002660_01	Info	TNFRSF1A-associated via death domain	H002660_01	L41690	89862	TRADD	Acetylation and Deacetylation of RelA in The Nucleus, Ceramide Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , MAPKinase Signaling Pathway, NF-kB Signaling Pathway, p38 MAPK Signaling Pathway , SODD/TNFR1 Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway	0.3157474	1.092
357	mapkPathway_h	BioCarta	H002559_01	Info	Mitogen-activated protein kinase kinase kinase 12	H002559_01	U07358	211601	MAP3K12	MAPKinase Signaling Pathway, Phosphatidylinositol signaling system	0.3172697	1.101
358	mapkPathway_h	BioCarta	H000203_01	Info	MAX protein	H000203_01	X60287	42712	MAX	MAPKinase Signaling Pathway, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , gene_regulation, transcription, tsonc	0.3220945	1.09
359	mapkPathway_h	BioCarta	H002700_01	Info	Transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kD)	H002700_01	L11695	220	TGFBR1	ALK in cardiac myocytes, Function of SLRP in Bone: An Integrated View, MAPKinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, p38 MAPK Signaling Pathway , TGF beta signaling pathway, Phosphatidylinositol signaling system, angiogenesis, development	0.3279632	0.903
360	mapkPathway_h	BioCarta	H015286_01	Info	Homo sapiens PAK2 mRNA, complete cds	H015286_01	AF092132	284275		FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, MAPKinase Signaling Pathway, TNFR1 Signaling Pathway, Phosphatidylinositol signaling system	0.4868167	1.068
361	mapkPathway_h	BioCarta	H001369_01	Info	Ribosomal protein S6 kinase, 90kD, polypeptide 4	H001369_01	AJ010119	105584	RPS6KA4	MAPKinase Signaling Pathway, Phosphatidylinositol signaling system	0.5303179	0.95
362	mapkPathway_h	BioCarta	H002340_01	Info	Mitogen-activated protein kinase kinase kinase 5	H002340_01	U67156	151988	MAP3K5	HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , The 4-1BB-dependent immune response	0.5393151	1.07
363	mapkPathway_h	BioCarta	H002236_01	Info	Mitogen-activated protein kinase kinase kinase kinase 1	H002236_01	U66464	86575	MAP4K1	MAPKinase Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor, Phosphatidylinositol signaling system	0.5747172	0.927
364	mapkPathway_h	BioCarta	H010968_01	Info	Mitogen-activated protein kinase kinase kinase 6	H010968_01	AF100318	194694	MAP3K6	MAPKinase Signaling Pathway	0.6538459	1.04
365	mapkPathway_h	BioCarta	H001386_01	Info	Mitogen-activated protein kinase kinase kinase 10	H001386_01	X90846	30223	MAP3K10	MAPKinase Signaling Pathway, Phosphatidylinositol signaling system	0.7007387	0.968
366	mapkPathway_h	BioCarta	H002757_01	Info	Mitogen-activated protein kinase 6	H002757_01	X80692	271980	MAPK6	MAPKinase Signaling Pathway, Phosphatidylinositol signaling system	0.7279385	1.033
367	mapkPathway_h	BioCarta	H002722_01	Info	Mitogen-activated protein kinase kinase 1	H002722_01	L11284	3446	MAP2K1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...	0.7377933	0.973
368	mapkPathway_h	BioCarta	H002136_01	Info	Mitogen-activating protein kinase kinase kinase kinase 2	H002136_01	U07349	82979	MAP4K2	MAPKinase Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, TNF/Stress Related Signaling, Phosphatidylinositol signaling system	0.8239916	1.021
369	mapkPathway_h	BioCarta	H002447_01	Info	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	H002447_01	M69043	81328	NFKBIA	Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAPKinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, T Cell Receptor Signaling Pathway, The 4-1BB-dependent immune respon ...	0.8245205	0.975
370	mapkPathway_h	BioCarta	H002580_01	Info	Mitogen-activated protein kinase-activated protein kinase 3	H002580_01	U09578	227789	MAPKAPK3	MAPKinase Signaling Pathway, Stress Induction of HSP Regulation, immunology	0.8269383	0.981
371	mapkPathway_h	BioCarta	H001376_01	Info	Homo sapiens mRNA; cDNA DKFZp566L084 (from clone DKFZp566L084)	H001376_01	AL133012	306440		Acetylation and Deacetylation of RelA in The Nucleus, AKT Signaling Pathway, CD40L Signaling Pathway, Double Stranded RNA Induced Gene Expression, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAPKinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Ras Signaling Pathway, Signal transduction through IL1R, TACI and BCMA stimulation of B cell immune responses., The 4-1BB-dependent immune response, TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway, cell_cycle, cell_signaling, signal_transduction	0.8639394	0.98
372	mapkPathway_h	BioCarta	H003711_01	Info	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)	H003711_01	M58603	83428	NFKB1	Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAPKinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a ...	0.8665095	1.017
373	mapkPathway_h	BioCarta	H003860_01	Info	Mitogen-activated protein kinase kinase kinase kinase 5	H003860_01	U77129	246970	MAP4K5	MAPKinase Signaling Pathway, The 4-1BB-dependent immune response, Phosphatidylinositol signaling system	0.8968151	1.015
374	mapkPathway_h	BioCarta	H003773_01	Info	Mitogen-activated protein kinase 4	H003773_01	X59727	269222	MAPK4	MAPKinase Signaling Pathway, Phosphatidylinositol signaling system	0.91886	1.013
375	mapkPathway_h	BioCarta	H003163_01	Info	CAMP responsive element binding protein 1	H003163_01	M27691	79194	CREB1	Ca++/ Calmodulin-dependent Protein Kinase Activation, Calcium Signaling by HBx of Hepatitis B virus, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia-Inducible Factor in the Cardiovascular System, Inhibition of Huntington\'s disease neurodegeneration by histone deacetylase inhibitors, MAPKinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Repression of Pain Sensation by the Transcriptional Regulator DREAM, Role of Erk5 in Neuronal Survival, Signaling Pathway from G-Protein Families, Transcription factor CREB and its extracellular signals, Transcription Regulation by Methyltransferase of CARM1, immunology	0.9300928	1.009
376	mapkPathway_h	BioCarta	H012856_01	Info	MAP kinase-interacting serine/threonine kinase 1	H012856_01	AB000409	5591	MKNK1	Erk1/Erk2 Mapk Signaling pathway, MAPKinase Signaling Pathway, mTOR Signaling Pathway, p38 MAPK Signaling Pathway , Regulation of eIF4e and p70 S6 Kinase, Phosphatidylinositol signaling system	0.9455231	0.992
377	mapkPathway_h	BioCarta	H002963_01	Info	V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptid	H002963_01	L19067	75569	RELA	Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc	0.9724165	1.003
378	mapkPathway_h	BioCarta	H014820_01	Info	Mitogen-activated protein kinase 9	H014820_01	NM_002752	246857	MAPK9	MAPKinase Signaling Pathway, Phosphatidylinositol signaling system	0.9883614	0.998
379	MAP00010_Glycolysis_Gluconeogenesis_h	GenMAPP	H001935_01	Info	Glyceraldehyde-3-phosphate dehydrogenase	H001935_01	U34995	169476	GAPD		0.0001082	1.485
380	MAP00010_Glycolysis_Gluconeogenesis_h	GenMAPP	H002486_01	Info	Glucokinase (hexokinase 4, maturity onset diabetes of the young 2)	H002486_01	M90299	1270	GCK	Aminosugars metabolism, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Starch and sucrose metabolism, Streptomycin biosynthesis, immunology	0.0014569	1.288
381	MAP00010_Glycolysis_Gluconeogenesis_h	GenMAPP	H004823_01	Info	Aldolase C, fructose-bisphosphate	H004823_01	AF054987	155247	ALDOC	Carbon fixation, Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Inositol metabolism, Pentose phosphate pathway	0.001576	0.707
382	MAP00010_Glycolysis_Gluconeogenesis_h	GenMAPP	H003374_01	Info	Aldolase A, fructose-bisphosphate	H003374_01	M11560	273415	ALDOA	Downregulated of MTA-3 in ER-negative Breast Tumors, Carbon fixation, Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Inositol metabolism, Pentose phosphate pathway, immunology	0.0300936	1.252
383	MAP00010_Glycolysis_Gluconeogenesis_h	GenMAPP	H001878_01	Info	Enolase 1, (alpha)	H001878_01	M14328	254105	ENO1	Glycolysis Pathway, Glycolysis / Gluconeogenesis, Phenylalanine, tyrosine and tryptophan biosynthesis	0.0756084	1.187
384	MAP00010_Glycolysis_Gluconeogenesis_h	GenMAPP	H007138_01	Info	Phosphoglycerate kinase {alternatively spliced} [human, phosphoglycerate kinase deficient patient wi	H007138_01	S81916	169313		Glycolysis Pathway, Carbon fixation, Glycolysis / Gluconeogenesis, immunology	0.0923463	1.164
385	MAP00010_Glycolysis_Gluconeogenesis_h	GenMAPP	H001387_01	Info	Phosphofructokinase, platelet	H001387_01	D25328	99910	PFKP	Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology	0.101431	0.866
386	MAP00010_Glycolysis_Gluconeogenesis_h	GenMAPP	H001572_01	Info	Aldehyde dehydrogenase 3 family, member B2	H001572_01	U37519	87539	ALDH3B2	Glycolysis / Gluconeogenesis, Histidine metabolism, Phenylalanine metabolism, Tyrosine metabolism	0.1278934	0.831
387	MAP00010_Glycolysis_Gluconeogenesis_h	GenMAPP	H005470_01	Info	Homo sapiens mRNA; cDNA DKFZp762B245 (from clone DKFZp762B245); partial cds	H005470_01	AL162062	198182			0.1944956	1.125
388	MAP00010_Glycolysis_Gluconeogenesis_h	GenMAPP	H002972_01	Info	Lactate dehydrogenase A	H002972_01	X02152	2795	LDHA	Hypoxia-Inducible Factor in the Cardiovascular System, SARS Coronavirus Protease, Cysteine metabolism, Glycolysis / Gluconeogenesis, Propanoate metabolism, Pyruvate metabolism, immunology, misc	0.2007271	0.841
389	MAP00010_Glycolysis_Gluconeogenesis_h	GenMAPP	H003659_01	Info	Aldehyde dehydrogenase 3 family, member A2	H003659_01	U46689	159608	ALDH3A2	Perou's- Intrinsic- Breast-Cancer-Genes, Arginine and proline metabolism, Ascorbate and aldarate metabolism, beta-Alanine metabolism, Bile acid biosynthesis, Butanoate metabolism, Fatty acid metabolism, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Limonene and pinene degradation, Lysine degradation, Propanoate metabolism, Pyruvate metabolism, Tryptophan metabolism, Valine, leucine and isoleucine degradation	0.2326293	0.892
390	MAP00010_Glycolysis_Gluconeogenesis_h	GenMAPP	H001636_01	Info	Phosphoglycerate mutase 1 (brain)	H001636_01	J04173	181013	PGAM1	Glycolysis Pathway, Glycolysis / Gluconeogenesis, misc	0.2631445	1.109
391	MAP00010_Glycolysis_Gluconeogenesis_h	GenMAPP	H001378_01	Info	Phosphofructokinase, muscle	H001378_01	U24183	75160	PFKM	Phosphoinositides and their downstream targets., Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology	0.2927445	0.908
392	MAP00010_Glycolysis_Gluconeogenesis_h	GenMAPP	H001136_01	Info	Glucose-6-phosphatase, catalytic (glycogen storage disease type I, von Gierke disease)	H001136_01	U01120	242	G6PC	Galactose metabolism, Glycolysis / Gluconeogenesis, Starch and sucrose metabolism	0.3211576	0.901
393	MAP00010_Glycolysis_Gluconeogenesis_h	GenMAPP	H003068_01	Info	Pyruvate kinase, muscle	H003068_01	M26252	198281	PKM2	Carbon fixation, Glycolysis / Gluconeogenesis, Purine metabolism, Pyruvate metabolism	0.3246109	1.102
394	MAP00010_Glycolysis_Gluconeogenesis_h	GenMAPP	H000053_01	Info	BH3 interacting domain death agonist	H000053_01	AF042083	172894	BID	Apoptotic Signaling in Response to DNA Damage, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Role of Mitochondria in Apoptotic Signaling, immunology	0.4598136	1.076
395	MAP00010_Glycolysis_Gluconeogenesis_h	GenMAPP	H002609_01	Info	Aldehyde dehydrogenase 3 family, member B1	H002609_01	U10868	83155	ALDH3B1	Glycolysis / Gluconeogenesis, Histidine metabolism, Phenylalanine metabolism, Tyrosine metabolism	0.6584857	1.053
396	MAP00010_Glycolysis_Gluconeogenesis_h	GenMAPP	H001558_01	Info	Lactate dehydrogenase C	H001558_01	U13680	99881	LDHC		0.6951457	1.058
397	MAP00010_Glycolysis_Gluconeogenesis_h	GenMAPP	H003776_01	Info	Aldehyde dehydrogenase 2 family (mitochondrial)	H003776_01	X05409	195432	ALDH2	Arginine and proline metabolism, Ascorbate and aldarate metabolism, beta-Alanine metabolism, Bile acid biosynthesis, Butanoate metabolism, Fatty acid metabolism, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Limonene and pinene degradation, Lysine degradation, Propanoate metabolism, Pyruvate metabolism, Tryptophan metabolism, Valine, leucine and isoleucine degradation, immunology, pharmacology	0.7225282	0.971
398	MAP00010_Glycolysis_Gluconeogenesis_h	GenMAPP	H005249_01	Info	Homo sapiens 10q21 mRNA sequence	H005249_01	AF198444	279024		Arginine and proline metabolism, Ascorbate and aldarate metabolism, beta-Alanine metabolism, Bile acid biosynthesis, Butanoate metabolism, Fatty acid metabolism, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Limonene and pinene degradation, Lysine degradation, Phenylalanine metabolism, Propanoate metabolism, Pyruvate metabolism, Tryptophan metabolism, Tyrosine metabolism, Valine, leucine and isoleucine degradation	0.761598	0.965
399	MAP00010_Glycolysis_Gluconeogenesis_h	GenMAPP	H006795_01	Info	2,3-bisphosphoglycerate mutase	H006795_01	X04327	198365	BPGM	Glycolysis / Gluconeogenesis	0.8901914	1.013
400	MAP00010_Glycolysis_Gluconeogenesis_h	GenMAPP	H001385_01	Info	Phosphofructokinase, liver	H001385_01	X15573	155455	PFKL	Glycolysis Pathway, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology	0.9581627	1.005
401	MAP00010_Glycolysis_Gluconeogenesis_h	GenMAPP	H001547_01	Info	Aldehyde dehydrogenase 3 family, member A1	H001547_01	M74542	575	ALDH3A1	Arginine and proline metabolism, Ascorbate and aldarate metabolism, beta-Alanine metabolism, Bile acid biosynthesis, Butanoate metabolism, Fatty acid metabolism, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Limonene and pinene degradation, Lysine degradation, Phenylalanine metabolism, Propanoate metabolism, Pyruvate metabolism, Tryptophan metabolism, Tyrosine metabolism, Valine, leucine and isoleucine degradation	0.999646	1
402	pyk2Pathway_h	BioCarta	H003200_01	Info	Mitogen-activated protein kinase kinase 3	H003200_01	D87116	180533	MAP2K3	fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway	0.0009666	1.561
403	pyk2Pathway_h	BioCarta	H002055_01	Info	Growth factor receptor-bound protein 2	H002055_01	M96995	296381	GRB2	Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...	0.0022348	1.459
404	pyk2Pathway_h	BioCarta	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
405	pyk2Pathway_h	BioCarta	H002895_01	Info	Mitogen-activated protein kinase 14	H002895_01	L35263	79107	MAPK14	BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAPKinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm ...	0.0086925	1.429
406	pyk2Pathway_h	BioCarta	H002573_01	Info	Protein tyrosine kinase 2 beta	H002573_01	U43522	20313	PTK2B	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CXCR4 Signaling Pathway, IL-7 Signal Transduction, Ion Channel and Phorbal Esters Signaling Pathway, Links between Pyk2 and Map Kinases, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Thrombin signaling and protease-activated receptors, angiogenesis, immunology, signal_transduction	0.0091935	1.367
407	pyk2Pathway_h	BioCarta	H003611_01	Info	Mitogen-activated protein kinase kinase 4	H003611_01	L36870	75217	MAP2K4	Perou's- Intrinsic- Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system	0.012502	0.753
408	pyk2Pathway_h	BioCarta	H003332_01	Info	V-crk avian sarcoma virus CT10 oncogene homolog-like	H003332_01	X59656	37078	CRKL	IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, Signaling of Hepatocyte Growth Factor Receptor, tsonc	0.0164206	0.675
409	pyk2Pathway_h	BioCarta	H001365_01	Info	Protein kinase C, beta 1	H001365_01	X07109	77202	PRKCB1	Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbal Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction	0.0304335	1.379
410	pyk2Pathway_h	BioCarta	H003178_01	Info	Mitogen-activated protein kinase 3	H003178_01	X60188	861	MAPK3	Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...	0.0986041	1.184
411	pyk2Pathway_h	BioCarta	H002287_01	Info	P21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related)	H002287_01	U24152	62402	PAK1	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, FAS signaling pathway ( CD95 ), fMLP induced chemokine gene expression in HMC-1 cells, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Rac 1 cell motility signaling pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, TNFR1 Signaling Pathway	0.1104284	0.815
412	pyk2Pathway_h	BioCarta	H003158_01	Info	Mitogen-activated protein kinase 8	H003158_01	L26318	190913	MAPK8	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...	0.1287835	1.166
413	pyk2Pathway_h	BioCarta	H002501_01	Info	Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	H002501_01	D25274	173737	RAC1	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signalling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments	0.1980127	1.118
414	pyk2Pathway_h	BioCarta	H002405_01	Info	Mitogen-activated protein kinase kinase 2	H002405_01	L11285	72241	MAP2K2	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor	0.3118803	1.093
415	pyk2Pathway_h	BioCarta	H011336_01	Info	Guanine nucleotide binding protein (G protein), q polypeptide	H011336_01	U43083	296261	GNAQ	Activation of PKC through G protein coupled receptor, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CCR3 signaling in Eosinophils, CXCR4 Signaling Pathway, Effects of calcineurin in Keratinocyte Differentiation, G-Protein Signaling Through Tubby Proteins, Links between Pyk2 and Map Kinases, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase, Signaling Pathway from G-Protein Families, Thrombin signaling and protease-activated receptors, immunology	0.3713616	0.89
416	pyk2Pathway_h	BioCarta	H002722_01	Info	Mitogen-activated protein kinase kinase 1	H002722_01	L11284	3446	MAP2K1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...	0.7377933	0.973
417	pyk2Pathway_h	BioCarta	H002404_01	Info	Synaptotagmin I	H002404_01	M55047	154679	SYT1		0.8170962	0.971
418	pyk2Pathway_h	BioCarta	H000579_01	Info	Calmodulin 2 (phosphorylase kinase, delta)	H000579_01	D45887	182278	CALM2		0.9689776	1.004
419	mta3Pathway_h	BioCarta	H001935_01	Info	Glyceraldehyde-3-phosphate dehydrogenase	H001935_01	U34995	169476	GAPD		0.0001082	1.485
420	mta3Pathway_h	BioCarta	H002279_01	Info	Metastasis associated 1	H002279_01	U35113	101448	MTA1	Downregulated of MTA-3 in ER-negative Breast Tumors	0.0268932	0.814
421	mta3Pathway_h	BioCarta	H003374_01	Info	Aldolase A, fructose-bisphosphate	H003374_01	M11560	273415	ALDOA	Downregulated of MTA-3 in ER-negative Breast Tumors, Carbon fixation, Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Inositol metabolism, Pentose phosphate pathway, immunology	0.0300936	1.252
422	mta3Pathway_h	BioCarta	H015409_01	Info	Hypothetical protein FLJ13940	H015409_01	NM_025019	287610	FLJ13940		0.0928487	1.183
423	mta3Pathway_h	BioCarta	H003339_01	Info	Heat shock 27kD protein 2	H003339_01	D89617	78846	HSPB2		0.4094065	0.924
424	gata3Pathway_h	BioCarta	H003200_01	Info	Mitogen-activated protein kinase kinase 3	H003200_01	D87116	180533	MAP2K3	fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway	0.0009666	1.561
425	gata3Pathway_h	BioCarta	H002406_01	Info	Jun B proto-oncogene	H002406_01	X51345	198951	JUNB	GATA3 participate in activating the Th2 cytokine genes expression, tsonc	0.0021761	1.408
426	gata3Pathway_h	BioCarta	H003415_01	Info	Protein kinase, cAMP-dependent, catalytic, beta	H003415_01	M34181	87773	PRKACB	Perou's- Intrinsic- Breast-Cancer-Genes, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction	0.0048904	0.647
427	gata3Pathway_h	BioCarta	H002895_01	Info	Mitogen-activated protein kinase 14	H002895_01	L35263	79107	MAPK14	BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAPKinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm ...	0.0086925	1.429
428	gata3Pathway_h	BioCarta	H006601_01	Info	V-maf musculoaponeurotic fibrosarcoma (avian) oncogene homolog	H006601_01	AF055376	30250	MAF	GATA3 participate in activating the Th2 cytokine genes expression, tsonc	0.079493	0.812
429	gata3Pathway_h	BioCarta	H001698_01	Info	Protein kinase, cAMP-dependent, regulatory, type II, alpha	H001698_01	X14968	289075	PRKAR2A	AKAP95 role in mitosis and chromosome dynamics, Protein Kinase A at the Centrosome, Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation	0.2569617	1.125
430	gata3Pathway_h	BioCarta	H000645_01	Info	Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	H000645_01	M33336	183037	PRKAR1A	Activation of cAMP-dependent protein kinase, PKA, cell_cycle, cell_signaling, signal_transduction	0.4305614	0.935
431	gata3Pathway_h	BioCarta	H002045_01	Info	Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	H002045_01	U80917	96149	NFATC1	BCR Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Effects of calcineurin in Keratinocyte Differentiation, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Role of MEF2D in T-cell Apoptosis, Signaling Pathway from G-Protein Families, T Cell Receptor Signaling Pathway, immunology	0.623508	1.051
432	fcer1Pathway_h	In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.	H000403_01	Info	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	H000403_01	M33195	743	FCER1G	Fc Epsilon Receptor I Signaling in Mast Cells	0.0002683	2.278
433	fcer1Pathway_h	In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.	H002055_01	Info	Growth factor receptor-bound protein 2	H002055_01	M96995	296381	GRB2	Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...	0.0022348	1.459
434	fcer1Pathway_h	In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
435	fcer1Pathway_h	In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.	H002878_01	Info	V-yes-1 Yamaguchi sarcoma viral related oncogene homolog	H002878_01	M16038	80887	LYN	BCR Signaling Pathway, Eph Kinases and ephrins support platelet aggregation, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., immunology, signal_transduction, tsonc	0.0068841	1.545
436	fcer1Pathway_h	In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.	H003611_01	Info	Mitogen-activated protein kinase kinase 4	H003611_01	L36870	75217	MAP2K4	Perou's- Intrinsic- Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system	0.012502	0.753
437	fcer1Pathway_h	In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.	H001365_01	Info	Protein kinase C, beta 1	H001365_01	X07109	77202	PRKCB1	Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbal Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction	0.0304335	1.379
438	fcer1Pathway_h	In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.	H003178_01	Info	Mitogen-activated protein kinase 3	H003178_01	X60188	861	MAPK3	Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...	0.0986041	1.184
439	fcer1Pathway_h	In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.	H003158_01	Info	Mitogen-activated protein kinase 8	H003158_01	L26318	190913	MAPK8	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...	0.1287835	1.166
440	fcer1Pathway_h	In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.	H003870_01	Info	Bruton agammaglobulinemia tyrosine kinase	H003870_01	NM_000061	159494	BTK	BCR Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., cell_cycle, cell_signaling, immunology, signal_transduction	0.251649	1.148
441	fcer1Pathway_h	In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.	H003309_01	Info	Mitogen-activated protein kinase kinase 7	H003309_01	AF013589	110299	MAP2K7	Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAPKinase Signaling Pathway	0.3044184	1.088
442	fcer1Pathway_h	In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.	H001979_01	Info	Protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta)	H001979_01	M29551	151531	PPP3CB	cell_cycle, cell_signaling	0.3386238	0.898
443	fcer1Pathway_h	In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.	H015286_01	Info	Homo sapiens PAK2 mRNA, complete cds	H015286_01	AF092132	284275		FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, MAPKinase Signaling Pathway, TNFR1 Signaling Pathway, Phosphatidylinositol signaling system	0.4868167	1.068
444	fcer1Pathway_h	In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.	H003578_01	Info	Protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma)	H003578_01	S46622	75206	PPP3CC		0.5197011	0.934
445	fcer1Pathway_h	In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.	H002045_01	Info	Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	H002045_01	U80917	96149	NFATC1	BCR Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Effects of calcineurin in Keratinocyte Differentiation, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Role of MEF2D in T-cell Apoptosis, Signaling Pathway from G-Protein Families, T Cell Receptor Signaling Pathway, immunology	0.623508	1.051
446	fcer1Pathway_h	In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.	H000983_01	Info	Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide	H000983_01	X06948	897	FCER1A	Fc Epsilon Receptor I Signaling in Mast Cells, immunology	0.6468177	0.954
447	fcer1Pathway_h	In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.	H002470_01	Info	Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	H002470_01	L41067	172674	NFATC3	immunology	0.7190859	0.97
448	fcer1Pathway_h	In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.	H002722_01	Info	Mitogen-activated protein kinase kinase 1	H002722_01	L11284	3446	MAP2K1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...	0.7377933	0.973
449	fcer1Pathway_h	In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.	H002404_01	Info	Synaptotagmin I	H002404_01	M55047	154679	SYT1		0.8170962	0.971
450	fcer1Pathway_h	In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.	H000579_01	Info	Calmodulin 2 (phosphorylase kinase, delta)	H000579_01	D45887	182278	CALM2		0.9689776	1.004
451	metPathway_h	BioCarta	H002055_01	Info	Growth factor receptor-bound protein 2	H002055_01	M96995	296381	GRB2	Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...	0.0022348	1.459
452	metPathway_h	BioCarta	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
453	metPathway_h	BioCarta	H002573_01	Info	Protein tyrosine kinase 2 beta	H002573_01	U43522	20313	PTK2B	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CXCR4 Signaling Pathway, IL-7 Signal Transduction, Ion Channel and Phorbal Esters Signaling Pathway, Links between Pyk2 and Map Kinases, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Thrombin signaling and protease-activated receptors, angiogenesis, immunology, signal_transduction	0.0091935	1.367
454	metPathway_h	BioCarta	H003332_01	Info	V-crk avian sarcoma virus CT10 oncogene homolog-like	H003332_01	X59656	37078	CRKL	IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, Signaling of Hepatocyte Growth Factor Receptor, tsonc	0.0164206	0.675
455	metPathway_h	BioCarta	H003178_01	Info	Mitogen-activated protein kinase 3	H003178_01	X60188	861	MAPK3	Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...	0.0986041	1.184
456	metPathway_h	BioCarta	H001600_01	Info	RAS p21 protein activator (GTPase activating protein) 1	H001600_01	M23379	758	RASA1	EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction	0.1015906	0.844
457	metPathway_h	BioCarta	H002287_01	Info	P21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related)	H002287_01	U24152	62402	PAK1	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, FAS signaling pathway ( CD95 ), fMLP induced chemokine gene expression in HMC-1 cells, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Rac 1 cell motility signaling pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, TNFR1 Signaling Pathway	0.1104284	0.815
458	metPathway_h	BioCarta	H003158_01	Info	Mitogen-activated protein kinase 8	H003158_01	L26318	190913	MAPK8	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...	0.1287835	1.166
459	metPathway_h	BioCarta	H002112_01	Info	PTK2 protein tyrosine kinase 2	H002112_01	L13616	740	PTK2	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Apoptotic Signaling in Response to DNA Damage, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, CCR3 signaling in Eosinophils, Cell to Cell Adhesion Signaling, CXCR4 Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, HIV-I Nef: negative effector of Fas and TNF, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Phospholipids as signalling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Trefoil Factors Initiate Mucosal Healing, uCalpain and friends in Cell spread, VEGF, Hypoxia, and Angiogenesis, angiogenesis, signal_transduction	0.2346929	0.896
460	metPathway_h	BioCarta	H002632_01	Info	GRB2-associated binding protein 1	H002632_01	U43885	239706	GAB1	Signaling of Hepatocyte Growth Factor Receptor	0.3021702	1.095
461	metPathway_h	BioCarta	H002405_01	Info	Mitogen-activated protein kinase kinase 2	H002405_01	L11285	72241	MAP2K2	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor	0.3118803	1.093
462	metPathway_h	BioCarta	H000015_01	Info	Dedicator of cyto-kinesis 1	H000015_01	D50857	82295	DOCK1	Signaling of Hepatocyte Growth Factor Receptor, immunology	0.334442	0.886
463	metPathway_h	BioCarta	H003533_01	Info	Paxillin	H003533_01	U14588	102497	PXN	Agrin in Postsynaptic Differentiation, Apoptotic Signaling in Response to DNA Damage, Cell to Cell Adhesion Signaling, CXCR4 Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Signaling of Hepatocyte Growth Factor Receptor, uCalpain and friends in Cell spread, VEGF, Hypoxia, and Angiogenesis, immunology	0.4629128	1.067
464	metPathway_h	BioCarta	H002236_01	Info	Mitogen-activated protein kinase kinase kinase kinase 1	H002236_01	U66464	86575	MAP4K1	MAPKinase Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor, Phosphatidylinositol signaling system	0.5747172	0.927
465	metPathway_h	BioCarta	H002722_01	Info	Mitogen-activated protein kinase kinase 1	H002722_01	L11284	3446	MAP2K1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...	0.7377933	0.973
466	metPathway_h	BioCarta	H003724_01	Info	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	H003724_01	NM_002211	202661	ITGB1	Adhesion and Diapedesis of Lymphocytes, Adhesion Molecules on Lymphocyte, Agrin in Postsynaptic Differentiation, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, B Cell Survival Pathway, Cells and Molecules involved in local acute inflammatory response, Eph Kinases and ephrins support platelet aggregation, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Monocyte and its Surface Molecules, PTEN dependent cell cycle arrest and apoptosis, Ras-Independent pathway in NK cell-mediated cytotoxicity, Signaling of Hepatocyte Growth Factor Receptor, Trefoil Factors Initiate Mucosal Healing, uCalpain and friends in Cell spread, cell_signaling, immunology, metastasis	0.9378203	0.993
467	cell_motility_h	Any process involved in the controlled movement of a cell.	H002800_01	Info	Connective tissue growth factor	H002800_01	X78947	75511	CTGF	immunology, misc	0.0004011	0.555
468	cell_motility_h	Any process involved in the controlled movement of a cell.	H002931_01	Info	Selectin L (lymphocyte adhesion molecule 1)	H002931_01	M25280	82848	SELL	Adhesion and Diapedesis of Granulocytes, Adhesion and Diapedesis of Lymphocytes, Adhesion Molecules on Lymphocyte, Monocyte and its Surface Molecules, Neutrophil and Its Surface Molecules, cell_signaling, immunology, metastasis	0.0013165	2.024
469	cell_motility_h	Any process involved in the controlled movement of a cell.	H002895_01	Info	Mitogen-activated protein kinase 14	H002895_01	L35263	79107	MAPK14	BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAPKinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm ...	0.0086925	1.429
470	cell_motility_h	Any process involved in the controlled movement of a cell.	H000459_01	Info	Serine protease inhibitor, Kunitz type, 2	H000459_01	AF027205	31439	SPINT2		0.009031	0.736
471	cell_motility_h	Any process involved in the controlled movement of a cell.	H002944_01	Info	Interleukin 8	H002944_01	M17017	624	IL8	Adhesion and Diapedesis of Granulocytes, Adhesion and Diapedesis of Lymphocytes, Cells and Molecules involved in local acute inflammatory response, Cytokine Network, Cytokines and Inflammatory Response, Free Radical Induced Apoptosis, IL 17 Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Proepithelin Conversion to Epithelin and Wound Repair Control, Regulation of hematopoiesis by cytokines, immunology	0.0100881	0.681
472	cell_motility_h	Any process involved in the controlled movement of a cell.	H003332_01	Info	V-crk avian sarcoma virus CT10 oncogene homolog-like	H003332_01	X59656	37078	CRKL	IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, Signaling of Hepatocyte Growth Factor Receptor, tsonc	0.0164206	0.675
473	cell_motility_h	Any process involved in the controlled movement of a cell.	H000633_01	Info	Coronin, actin-binding protein, 1A	H000633_01	D44497	109606	CORO1A		0.0167926	1.342
474	cell_motility_h	Any process involved in the controlled movement of a cell.	H002936_01	Info	Macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	H002936_01	X70040	2942	MST1R	Msp/Ron Receptor Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction	0.0189711	0.747
475	cell_motility_h	Any process involved in the controlled movement of a cell.	H004577_01	Info	Vasodilator-stimulated phosphoprotein	H004577_01	Z46389	93183	VASP	cell_signaling, immunology, signal_transduction	0.0236006	1.288
476	cell_motility_h	Any process involved in the controlled movement of a cell.	H004361_01	Info	Homo sapiens thioredoxin delta 3 (TXN delta 3) mRNA, partial cds	H004361_01	AF065241	306243		Chaperones modulate interferon Signaling Pathway, immunology	0.028408	1.271
477	cell_motility_h	Any process involved in the controlled movement of a cell.	H002347_01	Info	Leukotriene b4 receptor (chemokine receptor-like 1)	H002347_01	D89078	28408	LTB4R	immunology	0.0284508	1.35
478	cell_motility_h	Any process involved in the controlled movement of a cell.	H002869_01	Info	Platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD)	H002869_01	NM_000430	77318	PAFAH1B1	Glycerophospholipid metabolism, immunology	0.0323993	0.822
479	cell_motility_h	Any process involved in the controlled movement of a cell.	H003130_01	Info	Interleukin 8 receptor, beta	H003130_01	L19593	846	IL8RB	immunology	0.0345675	1.307
480	cell_motility_h	Any process involved in the controlled movement of a cell.	H001342_01	Info	Lymphocyte-specific protein 1	H001342_01	M33552	56729	LSP1	immunology	0.0390011	1.407
481	cell_motility_h	Any process involved in the controlled movement of a cell.	H015282_01	Info	Dynein, axonemal, heavy polypeptide 9	H015282_01	AJ404468	284259	DNAH9		0.0393936	1.221
482	cell_motility_h	Any process involved in the controlled movement of a cell.	H005850_01	Info	Dynein, axonemal, heavy polypeptide 17-like	H005850_01	AB002355	169148	DNAH17L		0.0500062	1.217
483	cell_motility_h	Any process involved in the controlled movement of a cell.	H012622_01	Info	Actin related protein 2/3 complex, subunit 1A (41 kD)	H012622_01	AF006084	11538	ARPC1B		0.0686508	1.204
484	cell_motility_h	Any process involved in the controlled movement of a cell.	H001765_01	Info	Myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L)	H001765_01	D10522	75607	MACS	Effects of calcineurin in Keratinocyte Differentiation	0.1075359	1.166
485	cell_motility_h	Any process involved in the controlled movement of a cell.	H002937_01	Info	Fibronectin 1	H002937_01	X02761	287820	FN1	angiogenesis, cell_signaling, immunology, metastasis	0.128354	1.194
486	cell_motility_h	Any process involved in the controlled movement of a cell.	H003158_01	Info	Mitogen-activated protein kinase 8	H003158_01	L26318	190913	MAPK8	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...	0.1287835	1.166
487	cell_motility_h	Any process involved in the controlled movement of a cell.	H000967_01	Info	Thrombospondin 4	H000967_01	Z19585	75774	THBS4	angiogenesis	0.1424962	0.85
488	cell_motility_h	Any process involved in the controlled movement of a cell.	H015328_01	Info	Junctional adhesion molecule	H015328_01	AF172398	286218	JAM	Perou's- Intrinsic- Breast-Cancer-Genes	0.1497802	1.165
489	cell_motility_h	Any process involved in the controlled movement of a cell.	H011553_01	Info	Katanin p80 (WD40-containing) subunit B 1	H011553_01	AF052432	275675	KATNB1		0.1512807	0.867
490	cell_motility_h	Any process involved in the controlled movement of a cell.	H003564_01	Info	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	H003564_01	AB002329	212414	SEMA3E		0.1517956	0.885
491	cell_motility_h	Any process involved in the controlled movement of a cell.	H002110_01	Info	Coagulation factor II (thrombin) receptor	H002110_01	NM_001992	128087	F2R	Perou's- Intrinsic- Breast-Cancer-Genes, Acute Myocardial Infarction, Extrinsic Prothrombin Activation Pathway, Fibrinolysis Pathway, Intrinsic Prothrombin Activation Pathway, immunology	0.1560498	0.883
492	cell_motility_h	Any process involved in the controlled movement of a cell.	H002501_01	Info	Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	H002501_01	D25274	173737	RAC1	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signalling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments	0.1980127	1.118
493	cell_motility_h	Any process involved in the controlled movement of a cell.	H002477_01	Info	Neogenin (chicken) homolog 1	H002477_01	U61262	90408	NEO1	angiogenesis, metastasis	0.2084414	1.135
494	cell_motility_h	Any process involved in the controlled movement of a cell.	H002750_01	Info	Neuropeptide Y	H002750_01	K01911	1832	NPY		0.2221305	1.126
495	cell_motility_h	Any process involved in the controlled movement of a cell.	H010731_01	Info	Partner of RAC1 (arfaptin 2)	H010731_01	U52522	75139	POR1	Rac 1 cell motility signaling pathway	0.259825	0.88
496	cell_motility_h	Any process involved in the controlled movement of a cell.	H007632_01	Info	Type I transmembrane protein Fn14	H007632_01	AB035480	10086	FN14		0.2727261	0.885
497	cell_motility_h	Any process involved in the controlled movement of a cell.	H005765_01	Info	A kinase (PRKA) anchor protein 3	H005765_01	NM_006422	98397	AKAP3		0.2830261	1.114
498	cell_motility_h	Any process involved in the controlled movement of a cell.	H005714_01	Info	A kinase (PRKA) anchor protein 4	H005714_01	AF072756	97633	AKAP4		0.284392	1.108
499	cell_motility_h	Any process involved in the controlled movement of a cell.	H000220_01	Info	Guanine nucleotide binding protein (G protein), alpha 13	H000220_01	L22075	1666	GNA13	PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase, Thrombin signaling and protease-activated receptors	0.2922764	1.182
500	cell_motility_h	Any process involved in the controlled movement of a cell.	H013061_01	Info	Cerebral cell adhesion molecule	H013061_01	NM_016174	23954	LOC51148		0.3332267	0.884
501	cell_motility_h	Any process involved in the controlled movement of a cell.	H002922_01	Info	Annexin A1	H002922_01	X05908	78225	ANXA1	Corticosteroids and cardioprotection	0.348625	1.12
502	cell_motility_h	Any process involved in the controlled movement of a cell.	H013901_01	Info	Protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs	H013901_01	AB032968	20447	PAK4	Phosphatidylinositol signaling system	0.3636917	0.913
503	cell_motility_h	Any process involved in the controlled movement of a cell.	H000723_01	Info	Angio-associated, migratory cell protein	H000723_01	M95627	83347	AAMP		0.3859087	0.934
504	cell_motility_h	Any process involved in the controlled movement of a cell.	H002976_01	Info	G protein-coupled receptor 9	H002976_01	X95876	198252	GPR9	IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, mCalpain and friends in Cell motility, NO2-dependent IL 12 Pathway in NK cells, Selective expression of chemokine receptors during T-cell polarization	0.4390046	0.918
505	cell_motility_h	Any process involved in the controlled movement of a cell.	H013376_01	Info	Capping protein (actin filament) muscle Z-line, alpha 2	H013376_01	U03851	75546	CAPZA2		0.4421974	1.117
506	cell_motility_h	Any process involved in the controlled movement of a cell.	H011225_01	Info	Serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 2	H011225_01	AB006423	158308	SERPINI2		0.4705964	0.919
507	cell_motility_h	Any process involved in the controlled movement of a cell.	H004767_01	Info	Tetraspan 3	H004767_01	AK001326	100090	TSPAN-3		0.4723725	1.074
508	cell_motility_h	Any process involved in the controlled movement of a cell.	H015920_01	Info	Homo sapiens thioredoxin delta 3 (TXN delta 3) mRNA, partial cds	H015920_01	AF065241	306243		Chaperones modulate interferon Signaling Pathway, immunology	0.5292008	1.077
509	cell_motility_h	Any process involved in the controlled movement of a cell.	H010773_01	Info	Actin related protein 2/3 complex, subunit 4 (20 kD)	H010773_01	AF006087	323342	ARPC4		0.5595709	0.946
510	cell_motility_h	Any process involved in the controlled movement of a cell.	H000791_01	Info	Platelet-activating factor acetylhydrolase, isoform Ib, beta subunit (30kD)	H000791_01	D63390	93354	PAFAH1B2	immunology	0.5668546	0.933
511	cell_motility_h	Any process involved in the controlled movement of a cell.	H003496_01	Info	Small inducible cytokine subfamily B (Cys-X-Cys), member 10	H003496_01	X02530	2248	SCYB10		0.572348	1.053
512	cell_motility_h	Any process involved in the controlled movement of a cell.	H007284_01	Info	Chondroitin sulfate proteoglycan 4 (melanoma-associated)	H007284_01	X96753	9004	CSPG4		0.6004302	0.95
513	cell_motility_h	Any process involved in the controlled movement of a cell.	H003538_01	Info	Actin, beta	H003538_01	NM_001101	288061	ACTB	Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes	0.6253266	0.956
514	cell_motility_h	Any process involved in the controlled movement of a cell.	H003708_01	Info	Thioredoxin	H003708_01	X77584	76136	TXN	Chaperones modulate interferon Signaling Pathway, immunology	0.6582476	1.041
515	cell_motility_h	Any process involved in the controlled movement of a cell.	H002722_01	Info	Mitogen-activated protein kinase kinase 1	H002722_01	L11284	3446	MAP2K1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...	0.7377933	0.973
516	cell_motility_h	Any process involved in the controlled movement of a cell.	H006937_01	Info	Hypothetical protein FLJ10211	H006937_01	AK001073	274206	FLJ10211		0.8108637	0.973
517	cell_motility_h	Any process involved in the controlled movement of a cell.	H006776_01	Info	Tetraspan 1	H006776_01	AF065388	38972	TSPAN-1		0.819954	1.022
518	cell_motility_h	Any process involved in the controlled movement of a cell.	H013182_01	Info	ARP2 (actin-related protein 2, yeast) homolog	H013182_01	AF006082	42915	ACTR2		0.840062	0.978
519	cell_motility_h	Any process involved in the controlled movement of a cell.	H007017_01	Info	Extracellular link domain-containing 1	H007017_01	NM_006691	17917	XLKD1		0.841013	0.971
520	cell_motility_h	Any process involved in the controlled movement of a cell.	H011434_01	Info	ARP3 (actin-related protein 3, yeast) homolog	H011434_01	NM_005721	5321	ACTR3		0.8741333	1.017
521	cell_motility_h	Any process involved in the controlled movement of a cell.	H003854_01	Info	Burkitt lymphoma receptor 1, GTP-binding protein	H003854_01	X68149	113916	BLR1		0.882872	0.982
522	cell_motility_h	Any process involved in the controlled movement of a cell.	H002891_01	Info	Small inducible cytokine A4 (homologous to mouse Mip-1b)	H002891_01	J04130	75703	SCYA4	Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Selective expression of chemokine receptors during T-cell polarization	0.8975649	1.014
523	cell_motility_h	Any process involved in the controlled movement of a cell.	H000822_01	Info	Filamin A, alpha (actin-binding protein-280)	H000822_01	X53416	195464	FLNA	cell_signaling, metastasis	0.9573941	1.004
524	cell_motility_h	Any process involved in the controlled movement of a cell.	H009065_01	Info	Muskelin 1, intracellular mediator containing kelch motifs	H009065_01	NM_013255	288791	MKLN1		0.9931275	1.001
525	ca_nf_at_signalling_h	GEArray	H001935_01	Info	Glyceraldehyde-3-phosphate dehydrogenase	H001935_01	U34995	169476	GAPD		0.0001082	1.485
526	ca_nf_at_signalling_h	GEArray	H001032_01	Info	Cytotoxic T-lymphocyte-associated protein 4	H001032_01	L15006	247824	CTLA4	The Co-Stimulatory Signal During T-cell Activation, immunology	0.0001134	0.56
527	ca_nf_at_signalling_h	GEArray	H003672_01	Info	FOS-like antigen-1	H003672_01	X16707	283565	FOSL1	Bone Remodelling, tsonc	0.0019097	0.779
528	ca_nf_at_signalling_h	GEArray	H002406_01	Info	Jun B proto-oncogene	H002406_01	X51345	198951	JUNB	GATA3 participate in activating the Th2 cytokine genes expression, tsonc	0.0021761	1.408
529	ca_nf_at_signalling_h	GEArray	H000570_01	Info	CREB binding protein (Rubinstein-Taybi syndrome)	H000570_01	U47741	23598	CREBBP	gene_regulation, transcription	0.0048718	1.469
530	ca_nf_at_signalling_h	GEArray	H008667_01	Info	Calcineurin binding protein 1	H008667_01	NM_012295	7840	KIAA0330	Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Role of MEF2D in T-cell Apoptosis	0.0071054	1.322
531	ca_nf_at_signalling_h	GEArray	H002895_01	Info	Mitogen-activated protein kinase 14	H002895_01	L35263	79107	MAPK14	BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAPKinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm ...	0.0086925	1.429
532	ca_nf_at_signalling_h	GEArray	H002944_01	Info	Interleukin 8	H002944_01	M17017	624	IL8	Adhesion and Diapedesis of Granulocytes, Adhesion and Diapedesis of Lymphocytes, Cells and Molecules involved in local acute inflammatory response, Cytokine Network, Cytokines and Inflammatory Response, Free Radical Induced Apoptosis, IL 17 Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Proepithelin Conversion to Epithelin and Wound Repair Control, Regulation of hematopoiesis by cytokines, immunology	0.0100881	0.681
533	ca_nf_at_signalling_h	GEArray	H002831_01	Info	Fc fragment of IgG, low affinity IIIb, receptor for (CD16)	H002831_01	J04162	176663	FCGR3B	immunology	0.0108963	1.803
534	ca_nf_at_signalling_h	GEArray	H003493_01	Info	MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B)	H003493_01	X63380	78881	MEF2B		0.0145042	1.328
535	ca_nf_at_signalling_h	GEArray	H015723_01	Info	Fc fragment of IgG, low affinity IIIa, receptor for (CD16)	H015723_01	NM_000569	300983	FCGR3A	immunology	0.0160639	1.577
536	ca_nf_at_signalling_h	GEArray	H002997_01	Info	Vascular endothelial growth factor	H002997_01	AF022375	73793	VEGF	Actions of Nitric Oxide in the Heart, Hypoxia-Inducible Factor in the Cardiovascular System, VEGF, Hypoxia, and Angiogenesis, angiogenesis, misc	0.0306231	0.782
537	ca_nf_at_signalling_h	GEArray	H000343_01	Info	Early growth response 3	H000343_01	X63741	74088	EGR3	Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, cell_signaling	0.0317099	0.777
538	ca_nf_at_signalling_h	GEArray	H002149_01	Info	Cyclin-dependent kinase inhibitor 1A (p21, Cip1)	H002149_01	U03106	179665	CDKN1A	ATM Signaling Pathway, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, Effects of calcineurin in Keratinocyte Differentiation, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia and p53 in the Cardiovascular system, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, immunology, tsonc	0.0349766	1.236
539	ca_nf_at_signalling_h	GEArray	H001320_01	Info	GATA-binding protein 4	H001320_01	L34357	243987	GATA4	ALK in cardiac myocytes, Hop Pathway in Cardiac Development, NFAT and Hypertrophy of the heart (Transcription in the broken heart), gene_regulation, misc, transcription	0.0421967	0.782
540	ca_nf_at_signalling_h	GEArray	H003259_01	Info	Sp1 transcription factor	H003259_01	J03133	2021	SP1	Agrin in Postsynaptic Differentiation, Effects of calcineurin in Keratinocyte Differentiation, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, MAPKinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase protein component gene hTert Transcriptional Regulation , Overview of telomerase RNA component gene hTerc Transcriptional Regulation	0.0557417	0.814
541	ca_nf_at_signalling_h	GEArray	H002545_01	Info	CD69 antigen (p60, early T-cell activation antigen)	H002545_01	Z22576	82401	CD69	cell_cycle, cell_signaling, immunology	0.0914627	1.212
542	ca_nf_at_signalling_h	GEArray	H002710_01	Info	Interleukin 10	H002710_01	M57627	193717	IL10	Antigen Dependent B Cell Activation, Cytokine Network, Cytokines and Inflammatory Response, Dendritic cells in regulating TH1 and TH2 Development, IL-10 Anti-inflammatory Signaling Pathway, immunology	0.0986725	0.876
543	ca_nf_at_signalling_h	GEArray	H002287_01	Info	P21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related)	H002287_01	U24152	62402	PAK1	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, FAS signaling pathway ( CD95 ), fMLP induced chemokine gene expression in HMC-1 cells, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Rac 1 cell motility signaling pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, TNFR1 Signaling Pathway	0.1104284	0.815
544	ca_nf_at_signalling_h	GEArray	H000398_01	Info	Protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1	H000398_01	U49070	161362	PIN1	How Progesterone Initiates the Oocyte Maturation	0.1163659	1.163
545	ca_nf_at_signalling_h	GEArray	H001128_01	Info	Fc fragment of IgG, low affinity IIIb, receptor for (CD16)	H001128_01	X16863	176663	FCGR3B	immunology	0.1164721	1.303
546	ca_nf_at_signalling_h	GEArray	H010696_01	Info	NCK adaptor protein 2	H010696_01	AF047487	101695	NCK2		0.1245534	1.19
547	ca_nf_at_signalling_h	GEArray	H003158_01	Info	Mitogen-activated protein kinase 8	H003158_01	L26318	190913	MAPK8	Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...	0.1287835	1.166
548	ca_nf_at_signalling_h	GEArray	H014546_01	Info	Peptidylprolyl isomerase A (cyclophilin A)	H014546_01	NM_021130	182937	PPIA	IL-2 Receptor Beta Chain in T cell Activation	0.129858	1.176
549	ca_nf_at_signalling_h	GEArray	H012917_01	Info	Homo sapiens clone 25048 mRNA sequence	H012917_01	AF131776	321572			0.1524925	0.87
550	ca_nf_at_signalling_h	GEArray	H003550_01	Info	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	H003550_01	S76638	73090	NFKB2	gene_regulation, immunology, transcription, tsonc	0.1593331	1.165
551	ca_nf_at_signalling_h	GEArray	H000372_01	Info	Early growth response 2 (Krox-20 (Drosophila) homolog)	H000372_01	NM_000399	1395	EGR2	Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, immunology	0.1772326	0.796
552	ca_nf_at_signalling_h	GEArray	H003309_01	Info	Mitogen-activated protein kinase kinase 7	H003309_01	AF013589	110299	MAP2K7	Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAPKinase Signaling Pathway	0.3044184	1.088
553	ca_nf_at_signalling_h	GEArray	H001979_01	Info	Protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta)	H001979_01	M29551	151531	PPP3CB	cell_cycle, cell_signaling	0.3386238	0.898
554	ca_nf_at_signalling_h	GEArray	H000650_01	Info	Glycogen synthase kinase 3 beta	H000650_01	L33801	78802	GSK3B	ALK in cardiac myocytes, Cell Cycle: G1/S Check Point , Deregulation of CDK5 in Alzheimers Disease, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Presenilin action in Notch and Wnt signaling, Regulation of eIF2, Segmentation Clock, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Sonic Hedgehog (Shh) Pathway, WNT Signaling Pathway, Phosphatidylinositol signaling system	0.353328	1.118
555	ca_nf_at_signalling_h	GEArray	H001957_01	Info	Interleukin 1, beta	H001957_01	M15330	126256	IL1B	IL 5 Signaling Pathway, Msp/Ron Receptor Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, immunology	0.4390274	1.089
556	ca_nf_at_signalling_h	GEArray	H003578_01	Info	Protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma)	H003578_01	S46622	75206	PPP3CC		0.5197011	0.934
557	ca_nf_at_signalling_h	GEArray	H002104_01	Info	Nucleoporin 214kD (CAIN)	H002104_01	D14689	170285	NUP214		0.5384146	1.074
558	ca_nf_at_signalling_h	GEArray	H001952_01	Info	Ribosomal protein L13a	H001952_01	X56932	119122	RPL13A		0.565051	1.059
559	ca_nf_at_signalling_h	GEArray	H003650_01	Info	Interleukin 2 receptor, alpha	H003650_01	X01057	1724	IL2RA	IL 2 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Role of Tob in T-cell activation, Th1/Th2 Differentiation, immunology	0.5932248	1.054
560	ca_nf_at_signalling_h	GEArray	H007966_01	Info	FK506-binding protein 1B (12.6 kD)	H007966_01	D38037	77643	FKBP1B		0.6042574	0.956
561	ca_nf_at_signalling_h	GEArray	H012106_01	Info	Src-like-adapter	H012106_01	D89077	75367	SLA		0.6044071	0.939
562	ca_nf_at_signalling_h	GEArray	H002812_01	Info	Protein tyrosine phosphatase, receptor type, C	H002812_01	Y00062	170121	PTPRC	Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, B Lymphocyte Cell Surface Molecules, Lck and Fyn tyrosine kinases in initiation of TCR Activation, T Cytotoxic Cell Surface Molecules, T Helper Cell Surface Molecules, cell_cycle, cell_signaling, immunology	0.6066202	1.093
563	ca_nf_at_signalling_h	GEArray	H006762_01	Info	Alu-binding protein with zinc finger domain	H006762_01	U82613	289104	ABP/ZF		0.6091962	0.938
564	ca_nf_at_signalling_h	GEArray	H002045_01	Info	Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	H002045_01	U80917	96149	NFATC1	BCR Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Effects of calcineurin in Keratinocyte Differentiation, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Role of MEF2D in T-cell Apoptosis, Signaling Pathway from G-Protein Families, T Cell Receptor Signaling Pathway, immunology	0.623508	1.051
565	ca_nf_at_signalling_h	GEArray	H003538_01	Info	Actin, beta	H003538_01	NM_001101	288061	ACTB	Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes	0.6253266	0.956
566	ca_nf_at_signalling_h	GEArray	H000983_01	Info	Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide	H000983_01	X06948	897	FCER1A	Fc Epsilon Receptor I Signaling in Mast Cells, immunology	0.6468177	0.954
567	ca_nf_at_signalling_h	GEArray	H002570_01	Info	Interleukin 2	H002570_01	S82692	89679	IL2	Antigen Dependent B Cell Activation, Cytokine Network, Cytokines and Inflammatory Response, IL 18 Signaling Pathway, IL 2 signaling pathway, OX40 Signaling Pathway, Regulation of hematopoiesis by cytokines, Role of Tob in T-cell activation, Selective expression of chemokine receptors during T-cell polarization, Th1/Th2 Differentiation, The 4-1BB-dependent immune response, The Co-Stimulatory Signal During T-cell Activation, immunology	0.6483346	1.043
568	ca_nf_at_signalling_h	GEArray	H003110_01	Info	Interleukin 6 (interferon, beta 2)	H003110_01	X04430	93913	IL6	Cells and Molecules involved in local acute inflammatory response, Cytokine Network, Cytokines and Inflammatory Response, Erythrocyte Differentiation Pathway, IL 17 Signaling Pathway, IL 5 Signaling Pathway, IL 6 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, Low-density lipoprotein (LDL) pathway during atherogenesis, Regulation of hematopoiesis by cytokines, Role of ERBB2 in Signal Transduction and Oncology, Signal transduction through IL1R, immunology	0.680804	1.036
569	ca_nf_at_signalling_h	GEArray	H001974_01	Info	BCL2-antagonist of cell death	H001974_01	U66879	76366	BAD	AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phosphoinositides and their downstream targets., Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Trefoil Factors Initiate Mucosal Healing, apoptosis, development	0.6985187	0.954
570	ca_nf_at_signalling_h	GEArray	H003153_01	Info	Interleukin 3 (colony-stimulating factor, multiple)	H003153_01	M20137	694	IL3	Cytokine Network, Cytokines and Inflammatory Response, Dendritic cells in regulating TH1 and TH2 Development, Erythrocyte Differentiation Pathway, IL 17 Signaling Pathway, IL 3 signaling pathway, Regulation of BAD phosphorylation, Regulation of hematopoiesis by cytokines, The Role of Eosinophils in the Chemokine Network of Allergy, immunology	0.7001094	1.037
571	ca_nf_at_signalling_h	GEArray	H002470_01	Info	Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	H002470_01	L41067	172674	NFATC3	immunology	0.7190859	0.97
572	ca_nf_at_signalling_h	GEArray	H003043_01	Info	Tumor necrosis factor (ligand) superfamily, member 5 (hyper-IgM syndrome)	H003043_01	X68550	652	TNFSF5	angiogenesis, cell_cycle, cell_signaling, immunology, metastasis	0.7231202	1.028
573	ca_nf_at_signalling_h	GEArray	H001267_01	Info	CD3Z antigen, zeta polypeptide (TiT3 complex)	H001267_01	NM_000734	97087	CD3Z	immunology	0.8300402	1.024
574	ca_nf_at_signalling_h	GEArray	H011554_01	Info	Vav 3 oncogene	H011554_01	NM_006113	267659	VAV3		0.8411784	1.028
575	ca_nf_at_signalling_h	GEArray	H012662_01	Info	Homo sapiens cDNA FLJ10205 fis, clone HEMBA1004954	H012662_01	AK001067	6226			0.8484663	1.017
576	ca_nf_at_signalling_h	GEArray	H011889_01	Info	Glucocorticoid receptor DNA binding factor 1	H011889_01	M73077	102548	GRLF1	Perou's- Intrinsic- Breast-Cancer-Genes	0.876973	0.984
577	ca_nf_at_signalling_h	GEArray	H012455_01	Info	KIAA1291 protein	H012455_01	AB033117	9805	KIAA1291		0.9257104	1.011
578	ca_nf_at_signalling_h	GEArray	H003151_01	Info	E1A binding protein p300	H003151_01	U01877	25272	EP300	Acetylation and Deacetylation of RelA in The Nucleus, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Control of Gene Expression by Vitamin D Receptor, Hypoxia and p53 in the Cardiovascular system, Hypoxia-Inducible Factor in the Cardiovascular System, IL-7 Signal Transduction, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Melanocyte Development and Pigmentation Pathway, Multi-step Regulation of Transcription by Pitx2, NFkB activation by Nontypeable Hemophilus influenzae, Pelp1 Modulation of Estrogen Receptor Activity, Role of ERBB2 in Signal Transduction and Oncology, Role of MEF2D in T-cell Apoptosis, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, TGF beta signaling pathway, Transcription Regulation by Methyltransferase of CARM1, gene_regulation, transcription	0.9607239	1.004
579	ca_nf_at_signalling_h	GEArray	H000579_01	Info	Calmodulin 2 (phosphorylase kinase, delta)	H000579_01	D45887	182278	CALM2		0.9689776	1.004
580	ca_nf_at_signalling_h	GEArray	H002963_01	Info	V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptid	H002963_01	L19067	75569	RELA	Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc	0.9724165	1.003
581	ca_nf_at_signalling_h	GEArray	H000247_01	Info	Sp3 transcription factor	H000247_01	X68560	44450	SP3	Effects of calcineurin in Keratinocyte Differentiation, Overview of telomerase protein component gene hTert Transcriptional Regulation , Overview of telomerase RNA component gene hTerc Transcriptional Regulation	0.985621	0.998
582	ca_nf_at_signalling_h	GEArray	H014820_01	Info	Mitogen-activated protein kinase 9	H014820_01	NM_002752	246857	MAPK9	MAPKinase Signaling Pathway, Phosphatidylinositol signaling system	0.9883614	0.998
583	nfatPathway_h	BioCarta	H000570_01	Info	CREB binding protein (Rubinstein-Taybi syndrome)	H000570_01	U47741	23598	CREBBP	gene_regulation, transcription	0.0048718	1.469
584	nfatPathway_h	BioCarta	H003415_01	Info	Protein kinase, cAMP-dependent, catalytic, beta	H003415_01	M34181	87773	PRKACB	Perou's- Intrinsic- Breast-Cancer-Genes, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction	0.0048904	0.647
585	nfatPathway_h	BioCarta	H002893_01	Info	V-raf-1 murine leukemia viral oncogene homolog 1	H002893_01	X03484	85181	RAF1	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...	0.0062484	1.596
586	nfatPathway_h	BioCarta	H003006_01	Info	Serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 8	H003006_01	K02215	3697	SERPINA8	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Angiotensin-converting enzyme 2 regulates heart function, Bioactive Peptide Induced Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, immunology	0.0063778	1.296
587	nfatPathway_h	BioCarta	H002895_01	Info	Mitogen-activated protein kinase 14	H002895_01	L35263	79107	MAPK14	BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAPKinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm ...	0.0086925	1.429
588	nfatPathway_h	BioCarta	H010817_01	Info	Heart and neural crest derivatives expressed 2	H010817_01	AF087940	36029	HAND2	NFAT and Hypertrophy of the heart (Transcription in the broken heart)	0.0143304	1.266
589	nfatPathway_h	BioCarta	H003305_01	Info	Ribosomal protein S6 kinase, 70kD, polypeptide 1	H003305_01	M60724	86858	RPS6KB1	CTCF: First Multivalent Nuclear Factor, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, MAPKinase Signaling Pathway, mTOR Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Rac 1 cell motility signaling pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction	0.0214523	1.448
590	nfatPathway_h	BioCarta	H002145_01	Info	FK506-binding protein 1A (12kD)	H002145_01	M34539	752	FKBP1A	mTOR Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart)	0.0298997	1.239
591	nfatPathway_h	BioCarta	H001320_01	Info	GATA-binding protein 4	H001320_01	L34357	243987	GATA4	ALK in cardiac myocytes, Hop Pathway in Cardiac Development, NFAT and Hypertrophy of the heart (Transcription in the broken heart), gene_regulation, misc, transcription	0.0421967	0.782
592	nfatPathway_h	BioCarta	H002194_01	Info	Casein kinase 1, alpha 1	H002194_01