HELP

Description of the problem:

Number of classes: 2
Column of the Experiment Descriptors sheet that defines class variable: Group
Number of genes used for random variance estimation: 8541
Number of genes that passed filtering criteria: 8541
Number of investigated pathways: 426 Broad/MIT
Random variance model was used


Pathways which have more genes differentially expressed among the phenotype classes than expected by chance:

Table - The first 21 Pathway are significant at the nominal 0.005 level of the LS permutation test or KS permutation test (sorted by p-values of the LS permutation test).

Broad PathwayPathway descriptionNumber of genesLS Permutation p-valueKS Permutation p-value
1h_egfPathwayThe epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.110.00017810.0007173
2h_at1rPathwayBinding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.190.00043680.0095861
3h_igf1PathwayBioCarta90.00062750.0004011
4h_ghPathwayBioCarta110.00107020.0324908
5h_pyk2PathwayBioCarta170.00117650.0104516
6h_spryPathwayBioCarta70.00123160.0038862
7MAPK_Cascade_hGO100.00129320.0167688
8h_radiation_sensitivityBioCarta200.00133310.0149414
9h_insulinPathwayBioCarta90.00146280.0090869
10h_cellcyclePathwayCyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.170.00160520.004197
11HOXA9_DOWN_hDorsam_et_al_2004250.00166790.0428986
12h_gata3PathwayBioCarta80.00220810.0692661
13h_ctla4PathwayT cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APCs CD80 or 86.110.00273360.0673271
14cell_cycle_checkpointII_hGO70.00310810.0028034
15h_g1PathwayBioCarta170.00422740.0077604
16EMT_UP_hJechlinger_et_al_2003320.00427580.0361
17h_tumor_supressorBioCarta150.00446610.0847671
18h_drug_resistance_and_metabolismBioCarta620.00453010.0571057
19h_pmlPathwayBioCarta100.00483560.0997659
20h_EGF_receptor_signaling_pathwayBioCarta90.00718640.0032054
21GPCRs_Class_A_Rhodopsin-like_hGO580.07160310.0022145

The significant genes can be found by clicking the link here.

Pathways which discriminate among classes by running the Hotelling T-square test for testing the hypothesis that for each pathway no genes in the set are differentially expressed between classes:

The number of principal components: 3

Table - The first 109 pathways are significant at the nominal 0.005 level of the Hotelling T-square test (sorted by p-values).

Broad PathwayPathway descriptionNumber of genesHotelling test p-value
1h_spryPathwayBioCarta71.1e-06
2h_ST_p38_MAPK_PathwaySignalling Transduction KE206.9e-06
3EMT_UP_hJechlinger_et_al_2003321.34e-05
4h_egfPathwayThe epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.111.92e-05
5h_insulinPathwayBioCarta93.63e-05
6h_igf1PathwayBioCarta93.67e-05
7h_il6PathwayBioCarta105.91e-05
8GLUCOSE_DOWN_hPeng_et_al_2002896.99e-05
9h_ghPathwayBioCarta119.38e-05
10h_il2rbPathwayBioCarta229.39e-05
11ST_T_Cell_Signal_Transduction_hSignalling Transduction KE249.47e-05
12h_pdgfPathwayBioCarta120.0001013
13h_igf1rPathwayBioCarta80.0001044
14MAPK_Cascade_hGO100.0001361
15FRASOR_ER_DOWN_hFrasor_et_al_2004370.0001462
16SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_hSignallingAlliance130.0001492
17h_mapkPathwayBioCarta540.0001557
18MAP00010_Glycolysis_Gluconeogenesis_hGenMAPP230.0001634
19h_pyk2PathwayBioCarta170.0001722
20h_mta3PathwayBioCarta50.0001966
21h_gata3PathwayBioCarta80.0002448
22h_fcer1PathwayIn mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.190.0002452
23h_metPathwayBioCarta160.0002699
24cell_motility_hAny process involved in the controlled movement of a cell.580.0002877
25ca_nf_at_signalling_hGEArray580.0002992
26h_nfatPathwayBioCarta290.0003129
27h_il3PathwayBioCarta80.0003487
28FETAL_LIVER_HS_ENRICHED_TF_JP_hManually Curated460.0004007
29h_epoPathwayErythropoietin, which activates the MAPK pathway, stimulates erythrocyte production and is an effective treatment for anemia.80.0004264
30h_nthiPathwayBioCarta150.0004378
31HOXA9_DOWN_hDorsam_et_al_2004250.0004546
32fmlppathway_hThe fMLP receptor is a G-protein coupled receptor in neutrophiles that recognizes formylated bacterial peptides and activates NADPH oxidase.200.0004828
33h_at1rPathwayBinding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.190.000559
34h_tumor_supressorBioCarta150.0005798
35NFKB_INDUCED_hHinata_et_al_2003600.000606
36DNA_DAMAGE_SIGNALLING_hGO660.0006144
37GPCRs_Class_A_Rhodopsin-like_hGO580.0007054
38MAP00230_Purine_metabolism_hGenMAPP500.0007068
39h_raccycdPathwayBioCarta150.0007662
40h_stressPathwayBioCarta150.0008401
41MAP00190_Oxidative_phosphorylation_hGenMAPP200.0009015
42h_atrbrcaPathwayBRCA1 and 2 block cell cycle progression in response to DNA damage and promote double-stranded break repair; mutations induce breast cancer susceptibility.120.0009417
43EMT_DOWN_hJechlinger_et_al_2003210.0009966
44h_ngfPathwayBioCarta80.0010117
45CR_TRANSCRIPTION_FACTORS_hPNAS_2013460.0011226
46h_erkPathwayCell growth is promoted by Ras activation of the anti-apoptotic p44/42 MAP kinase pathway.170.0011573
47h_ST_G_alpha_i_Pathway_Signalling Transduction KE200.0011874
48h_tpoPathwayBioCarta80.0012393
49h_gleevecPathwayBioCarta120.0012794
50h_il2PathwayBioCarta130.0013664
51h_pparaPathwayBioCarta340.0014403
52GNF_FEMALE_GENES_hna500.0016619
53MAP00510_N_Glycans_biosynthesis_hGenMAPP110.0016653
54CR_PROTEIN_MOD_hPNAS_2010960.0017479
55h_p27PathwayBioCarta100.0017628
56SA_PTEN_PATHWAY_hSigmaAldrich100.0018065
57CR_TRANSPORT_OF_VESICLES_hPNAS_2015180.002019
58h_il1rPathwayBioCarta150.002075
59h_tollPathwayBioCarta190.0022275
60MAP00240_Pyrimidine_metabolism_hGenMAPP290.0023595
61h_g2PathwayBioCarta180.002402
62h_gabaPathwayBioCarta50.002409
63h_keratinocytePathwayBioCarta260.0024116
64h_lairPathwayBioCarta90.0024136
65MAP00030_Pentose_phosphate_pathway_hGenMAPP110.0024356
66ANDROGEN_UP_GENES_hna320.0025209
67h_SIG_InsulinReceptorPathwayInCardiacMyocytesSignallingAlliance290.0025548
68h_crebPathwayCREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling.140.0027324
69h_ST_JNK_MAPK_PathwaySignalling Transduction KE240.0027719
70h_radiation_sensitivityBioCarta200.0027867
71h_mtorPathwayBioCarta140.0028072
72h_glycolysisPathwayBioCarta50.0029056
73shh_lisa_hManually Curated130.0030194
74h_ST_G_alpha_5_PathwaySignalling Transduction KE70.0030305
75h_ptdinsPathwayBioCarta160.0030497
76h_insulin_signallingBioCarta580.0030521
77h_biopeptidesPathwayExtracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases.190.0030677
78h_ST_Ga13_PathwaySignalling Transduction KE250.0031494
79h_ST_Dictyostelium_discoideum_cAMP_Chemotaxis_PathwaySignalling Transduction KE220.0031671
80cell_adhesion_hThe attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules.970.0032822
81h_ceramidePathwayCeramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type.160.0033054
82h_eea1PathwayThe FYVE-finger proteins EEA1 and HRS are localized to endosome membranes and regulate sorting and ubiquitination in the vesicle transport system.70.0033393
83ST_B_Cell_Antigen_Receptor_hSignalling Transduction KE240.0033761
84h_tidPathwayBioCarta90.0033789
85DOWNREG_BY_HOXA9_hManually Curated220.0034111
86ST_GRANULE_CELL_SURVIVAL_PATHWAY_hSignalling Transduction KE190.0035205
87h_bcrPathwayB cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen.170.0035561
88h_egfr_smrtePathwayEGF receptor activation inhibits SMRT, a transcriptional co-repressor that interacts with transcription factor complexes and gene silencers.60.0035752
89HEMO_TF_LIST_JP_hManually Curated450.0036197
90h_hcmvPathwayBioCarta110.0036815
91MAP00051_Fructose_and_mannose_metabolism_hGenMAPP120.003728
92MAP_kinase_kinase_activity_hGenMAPP50.0038348
93LEU_UP_hPeng_et_al_2002770.0038565
94h_p53PathwayBioCarta110.0038582
95h_ppargPathwayBioCarta60.0038969
96h_ST_ERK1_ERK2_MAPK_PathwaySignalling Transduction KE200.0039951
97MAP00710_Carbon_fixation_hGenMAPP80.004022
98h_drug_resistance_and_metabolismBioCarta620.0040238
99h_il10PathwayBioCarta70.0041077
100h_rbPathwayBioCarta90.0041223
101h_mprPathwayBioCarta140.0041417
102h_S1P_SignalingBioCarta170.0042391
103MAP00600_Sphingoglycolipid_metabolism_hGenMAPP80.0043908
104h_ST_Differentiation_Pathway_in_PC12_CellsSignalling Transduction KE240.0044761
105h_integrinPathwayBioCarta240.0046608
106h_longevityPathwayBioCarta50.0047172
107h_p53_signallingBioCarta580.0048118
108ST_ADRENERGIC_hSignalling Transduction KE240.0048368
109h_ptenPathwayBioCarta90.004882

The significant genes can be found by clicking the link here.

Table - Significant pathway which have more genes differentially expressed among the phenotype classes than expected by chance consist of the following genes (sorted by p-values).


Broad PathwayPathway descriptionUnique idAnno-
tations
DescriptionCloneGB accUG clusterGene symbolDefined genelistsParametric p-valueGeometric mean of ratios
(class Disesase /class Normal )
1
egfPathway_h
The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.
H002040_01
Info
Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)
H002040_01
X00588
77432
EGFR
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degredation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc
0.0004362
0.669
2
egfPathway_h
The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.
H002186_01
Info
Serum response factor (c-fos serum response element-binding transcription factor)
H002186_01
J03161
155321
SRF
EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription
0.0017465
0.722
3
egfPathway_h
The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.
H002055_01
Info
Growth factor receptor-bound protein 2
H002055_01
M96995
296381
GRB2
Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...
0.0022348
1.459
4
egfPathway_h
The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
5
egfPathway_h
The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.
H003611_01
Info
Mitogen-activated protein kinase kinase 4
H003611_01
L36870
75217
MAP2K4
Perou's- Intrinsic- Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system
0.012502
0.753
6
egfPathway_h
The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.
H001365_01
Info
Protein kinase C, beta 1
H001365_01
X07109
77202
PRKCB1
Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbal Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction
0.0304335
1.379
7
egfPathway_h
The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.
H003178_01
Info
Mitogen-activated protein kinase 3
H003178_01
X60188
861
MAPK3
Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...
0.0986041
1.184
8
egfPathway_h
The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.
H001600_01
Info
RAS p21 protein activator (GTPase activating protein) 1
H001600_01
M23379
758
RASA1
EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction
0.1015906
0.844
9
egfPathway_h
The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.
H003158_01
Info
Mitogen-activated protein kinase 8
H003158_01
L26318
190913
MAPK8
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...
0.1287835
1.166
10
egfPathway_h
The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.
H001349_01
Info
Janus kinase 1 (a protein tyrosine kinase)
H001349_01
M64174
50651
JAK1
EGF Signaling Pathway, IFN alpha signaling pathway, IFN gamma signaling pathway , IL 2 signaling pathway, IL 4 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, PDGF Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction
0.2754104
1.129
11
egfPathway_h
The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.
H002722_01
Info
Mitogen-activated protein kinase kinase 1
H002722_01
L11284
3446
MAP2K1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...
0.7377933
0.973
12
at1rPathway_h
Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.
H002040_01
Info
Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)
H002040_01
X00588
77432
EGFR
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degredation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc
0.0004362
0.669
13
at1rPathway_h
Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.
H002055_01
Info
Growth factor receptor-bound protein 2
H002055_01
M96995
296381
GRB2
Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...
0.0022348
1.459
14
at1rPathway_h
Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
15
at1rPathway_h
Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.
H003006_01
Info
Serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 8
H003006_01
K02215
3697
SERPINA8
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Angiotensin-converting enzyme 2 regulates heart function, Bioactive Peptide Induced Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, immunology
0.0063778
1.296
16
at1rPathway_h
Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.
H002573_01
Info
Protein tyrosine kinase 2 beta
H002573_01
U43522
20313
PTK2B
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CXCR4 Signaling Pathway, IL-7 Signal Transduction, Ion Channel and Phorbal Esters Signaling Pathway, Links between Pyk2 and Map Kinases, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Thrombin signaling and protease-activated receptors, angiogenesis, immunology, signal_transduction
0.0091935
1.367
17
at1rPathway_h
Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.
H003611_01
Info
Mitogen-activated protein kinase kinase 4
H003611_01
L36870
75217
MAP2K4
Perou's- Intrinsic- Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system
0.012502
0.753
18
at1rPathway_h
Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.
H003493_01
Info
MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B)
H003493_01
X63380
78881
MEF2B

0.0145042
1.328
19
at1rPathway_h
Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.
H001992_01
Info
Activating transcription factor 2
H001992_01
X15875
198166
ATF2
ALK in cardiac myocytes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , The 4-1BB-dependent immune response, The information-processing pathway at the IFN-beta enhancer
0.0178377
0.749
20
at1rPathway_h
Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.
H001365_01
Info
Protein kinase C, beta 1
H001365_01
X07109
77202
PRKCB1
Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbal Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction
0.0304335
1.379
21
at1rPathway_h
Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.
H003178_01
Info
Mitogen-activated protein kinase 3
H003178_01
X60188
861
MAPK3
Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...
0.0986041
1.184
22
at1rPathway_h
Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.
H002287_01
Info
P21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related)
H002287_01
U24152
62402
PAK1
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, FAS signaling pathway ( CD95 ), fMLP induced chemokine gene expression in HMC-1 cells, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Rac 1 cell motility signaling pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, TNFR1 Signaling Pathway
0.1104284
0.815
23
at1rPathway_h
Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.
H003158_01
Info
Mitogen-activated protein kinase 8
H003158_01
L26318
190913
MAPK8
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...
0.1287835
1.166
24
at1rPathway_h
Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.
H002501_01
Info
Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
H002501_01
D25274
173737
RAC1
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signalling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments
0.1980127
1.118
25
at1rPathway_h
Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.
H002112_01
Info
PTK2 protein tyrosine kinase 2
H002112_01
L13616
740
PTK2
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Apoptotic Signaling in Response to DNA Damage, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, CCR3 signaling in Eosinophils, Cell to Cell Adhesion Signaling, CXCR4 Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, HIV-I Nef: negative effector of Fas and TNF, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Phospholipids as signalling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Trefoil Factors Initiate Mucosal Healing, uCalpain and friends in Cell spread, VEGF, Hypoxia, and Angiogenesis, angiogenesis, signal_transduction
0.2346929
0.896
26
at1rPathway_h
Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.
H002405_01
Info
Mitogen-activated protein kinase kinase 2
H002405_01
L11285
72241
MAP2K2
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of ▀-arrestins in the activation and targeting of MAP kinases, Roles of ▀-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor
0.3118803
1.093
27
at1rPathway_h
Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.
H011336_01
Info
Guanine nucleotide binding protein (G protein), q polypeptide
H011336_01
U43083
296261
GNAQ
Activation of PKC through G protein coupled receptor, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CCR3 signaling in Eosinophils, CXCR4 Signaling Pathway, Effects of calcineurin in Keratinocyte Differentiation, G-Protein Signaling Through Tubby Proteins, Links between Pyk2 and Map Kinases, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase, Signaling Pathway from G-Protein Families, Thrombin signaling and protease-activated receptors, immunology
0.3713616
0.89
28
at1rPathway_h
Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.
H002722_01
Info
Mitogen-activated protein kinase kinase 1
H002722_01
L11284
3446
MAP2K1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...
0.7377933
0.973
29
at1rPathway_h
Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.
H002404_01
Info
Synaptotagmin I
H002404_01
M55047
154679
SYT1

0.8170962
0.971
30
at1rPathway_h
Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.
H000579_01
Info
Calmodulin 2 (phosphorylase kinase, delta)
H000579_01
D45887
182278
CALM2

0.9689776
1.004
31
igf1Pathway_h
BioCarta
H000732_01
Info
Insulin receptor substrate 1
H000732_01
S62539
96063
IRS1
Perou's- Intrinsic- Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology
0.0013348
0.643
32
igf1Pathway_h
BioCarta
H002186_01
Info
Serum response factor (c-fos serum response element-binding transcription factor)
H002186_01
J03161
155321
SRF
EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription
0.0017465
0.722
33
igf1Pathway_h
BioCarta
H002055_01
Info
Growth factor receptor-bound protein 2
H002055_01
M96995
296381
GRB2
Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...
0.0022348
1.459
34
igf1Pathway_h
BioCarta
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
35
igf1Pathway_h
BioCarta
H002473_01
Info
Insulin-like growth factor 1 receptor
H002473_01
NM_000875
239176
IGF1R
Perou's- Intrinsic- Breast-Cancer-Genes, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Erk1/Erk2 Mapk Signaling pathway, IGF-1 Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Telomeres, Telomerase, Cellular Aging, and Immortality, The IGF-1 Receptor and Longevity, immunology
0.079692
1.158
36
igf1Pathway_h
BioCarta
H003178_01
Info
Mitogen-activated protein kinase 3
H003178_01
X60188
861
MAPK3
Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...
0.0986041
1.184
37
igf1Pathway_h
BioCarta
H001600_01
Info
RAS p21 protein activator (GTPase activating protein) 1
H001600_01
M23379
758
RASA1
EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction
0.1015906
0.844
38
igf1Pathway_h
BioCarta
H003158_01
Info
Mitogen-activated protein kinase 8
H003158_01
L26318
190913
MAPK8
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...
0.1287835
1.166
39
igf1Pathway_h
BioCarta
H002722_01
Info
Mitogen-activated protein kinase kinase 1
H002722_01
L11284
3446
MAP2K1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...
0.7377933
0.973
40
ghPathway_h
BioCarta
H000732_01
Info
Insulin receptor substrate 1
H000732_01
S62539
96063
IRS1
Perou's- Intrinsic- Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology
0.0013348
0.643
41
ghPathway_h
BioCarta
H002186_01
Info
Serum response factor (c-fos serum response element-binding transcription factor)
H002186_01
J03161
155321
SRF
EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription
0.0017465
0.722
42
ghPathway_h
BioCarta
H002055_01
Info
Growth factor receptor-bound protein 2
H002055_01
M96995
296381
GRB2
Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...
0.0022348
1.459
43
ghPathway_h
BioCarta
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
44
ghPathway_h
BioCarta
H002890_01
Info
Ribosomal protein S6 kinase, 90kD, polypeptide 1
H002890_01
L07597
149957
RPS6KA1
Cell Cycle: G2/M Checkpoint, Erk1/Erk2 Mapk Signaling pathway, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, MAPKinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Role of Erk5 in Neuronal Survival, Transcription factor CREB and its extracellular signals, Phosphatidylinositol signaling system
0.0138896
1.42
45
ghPathway_h
BioCarta
H001365_01
Info
Protein kinase C, beta 1
H001365_01
X07109
77202
PRKCB1
Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbal Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction
0.0304335
1.379
46
ghPathway_h
BioCarta
H003178_01
Info
Mitogen-activated protein kinase 3
H003178_01
X60188
861
MAPK3
Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...
0.0986041
1.184
47
ghPathway_h
BioCarta
H002624_01
Info
Insulin receptor
H002624_01
X02160
89695
INSR
Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Growth Hormone Signaling Pathway, Insulin Signaling Pathway, immunology
0.433218
0.919
48
ghPathway_h
BioCarta
H002261_01
Info
Signal transducer and activator of transcription 5B
H002261_01
U47686
244613
STAT5B

0.441402
1.071
49
ghPathway_h
BioCarta
H009068_01
Info
Homo sapiens mRNA; cDNA DKFZp586N1323 (from clone DKFZp586N1323)
H009068_01
AL080218
24064


0.509279
1.056
50
ghPathway_h
BioCarta
H002722_01
Info
Mitogen-activated protein kinase kinase 1
H002722_01
L11284
3446
MAP2K1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...
0.7377933
0.973
51
pyk2Pathway_h
BioCarta
H003200_01
Info
Mitogen-activated protein kinase kinase 3
H003200_01
D87116
180533
MAP2K3
fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway
0.0009666
1.561
52
pyk2Pathway_h
BioCarta
H002055_01
Info
Growth factor receptor-bound protein 2
H002055_01
M96995
296381
GRB2
Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...
0.0022348
1.459
53
pyk2Pathway_h
BioCarta
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
54
pyk2Pathway_h
BioCarta
H002895_01
Info
Mitogen-activated protein kinase 14
H002895_01
L35263
79107
MAPK14
BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAPKinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm ...
0.0086925
1.429
55
pyk2Pathway_h
BioCarta
H002573_01
Info
Protein tyrosine kinase 2 beta
H002573_01
U43522
20313
PTK2B
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CXCR4 Signaling Pathway, IL-7 Signal Transduction, Ion Channel and Phorbal Esters Signaling Pathway, Links between Pyk2 and Map Kinases, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Thrombin signaling and protease-activated receptors, angiogenesis, immunology, signal_transduction
0.0091935
1.367
56
pyk2Pathway_h
BioCarta
H003611_01
Info
Mitogen-activated protein kinase kinase 4
H003611_01
L36870
75217
MAP2K4
Perou's- Intrinsic- Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system
0.012502
0.753
57
pyk2Pathway_h
BioCarta
H003332_01
Info
V-crk avian sarcoma virus CT10 oncogene homolog-like
H003332_01
X59656
37078
CRKL
IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, Signaling of Hepatocyte Growth Factor Receptor, tsonc
0.0164206
0.675
58
pyk2Pathway_h
BioCarta
H001365_01
Info
Protein kinase C, beta 1
H001365_01
X07109
77202
PRKCB1
Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbal Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction
0.0304335
1.379
59
pyk2Pathway_h
BioCarta
H003178_01
Info
Mitogen-activated protein kinase 3
H003178_01
X60188
861
MAPK3
Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...
0.0986041
1.184
60
pyk2Pathway_h
BioCarta
H002287_01
Info
P21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related)
H002287_01
U24152
62402
PAK1
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, FAS signaling pathway ( CD95 ), fMLP induced chemokine gene expression in HMC-1 cells, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Rac 1 cell motility signaling pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, TNFR1 Signaling Pathway
0.1104284
0.815
61
pyk2Pathway_h
BioCarta
H003158_01
Info
Mitogen-activated protein kinase 8
H003158_01
L26318
190913
MAPK8
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...
0.1287835
1.166
62
pyk2Pathway_h
BioCarta
H002501_01
Info
Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
H002501_01
D25274
173737
RAC1
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signalling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments
0.1980127
1.118
63
pyk2Pathway_h
BioCarta
H002405_01
Info
Mitogen-activated protein kinase kinase 2
H002405_01
L11285
72241
MAP2K2
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of ▀-arrestins in the activation and targeting of MAP kinases, Roles of ▀-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor
0.3118803
1.093
64
pyk2Pathway_h
BioCarta
H011336_01
Info
Guanine nucleotide binding protein (G protein), q polypeptide
H011336_01
U43083
296261
GNAQ
Activation of PKC through G protein coupled receptor, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CCR3 signaling in Eosinophils, CXCR4 Signaling Pathway, Effects of calcineurin in Keratinocyte Differentiation, G-Protein Signaling Through Tubby Proteins, Links between Pyk2 and Map Kinases, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase, Signaling Pathway from G-Protein Families, Thrombin signaling and protease-activated receptors, immunology
0.3713616
0.89
65
pyk2Pathway_h
BioCarta
H002722_01
Info
Mitogen-activated protein kinase kinase 1
H002722_01
L11284
3446
MAP2K1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...
0.7377933
0.973
66
pyk2Pathway_h
BioCarta
H002404_01
Info
Synaptotagmin I
H002404_01
M55047
154679
SYT1

0.8170962
0.971
67
pyk2Pathway_h
BioCarta
H000579_01
Info
Calmodulin 2 (phosphorylase kinase, delta)
H000579_01
D45887
182278
CALM2

0.9689776
1.004
68
spryPathway_h
BioCarta
H002040_01
Info
Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)
H002040_01
X00588
77432
EGFR
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degredation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc
0.0004362
0.669
69
spryPathway_h
BioCarta
H002055_01
Info
Growth factor receptor-bound protein 2
H002055_01
M96995
296381
GRB2
Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...
0.0022348
1.459
70
spryPathway_h
BioCarta
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
71
spryPathway_h
BioCarta
H002847_01
Info
Protein tyrosine phosphatase, receptor type, B
H002847_01
X54131
123641
PTPRB
Sprouty regulation of tyrosine kinase signals, cell_cycle, cell_signaling
0.0110757
1.299
72
spryPathway_h
BioCarta
H003178_01
Info
Mitogen-activated protein kinase 3
H003178_01
X60188
861
MAPK3
Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...
0.0986041
1.184
73
spryPathway_h
BioCarta
H001600_01
Info
RAS p21 protein activator (GTPase activating protein) 1
H001600_01
M23379
758
RASA1
EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction
0.1015906
0.844
74
spryPathway_h
BioCarta
H002722_01
Info
Mitogen-activated protein kinase kinase 1
H002722_01
L11284
3446
MAP2K1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...
0.7377933
0.973
75
MAPK_Cascade_h
GO
H003200_01
Info
Mitogen-activated protein kinase kinase 3
H003200_01
D87116
180533
MAP2K3
fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway
0.0009666
1.561
76
MAPK_Cascade_h
GO
H001648_01
Info
Myelin basic protein
H001648_01
M13577
69547
MBP

0.0014651
0.667
77
MAPK_Cascade_h
GO
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
78
MAPK_Cascade_h
GO
H002895_01
Info
Mitogen-activated protein kinase 14
H002895_01
L35263
79107
MAPK14
BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAPKinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm ...
0.0086925
1.429
79
MAPK_Cascade_h
GO
H003611_01
Info
Mitogen-activated protein kinase kinase 4
H003611_01
L36870
75217
MAP2K4
Perou's- Intrinsic- Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system
0.012502
0.753
80
MAPK_Cascade_h
GO
H003178_01
Info
Mitogen-activated protein kinase 3
H003178_01
X60188
861
MAPK3
Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...
0.0986041
1.184
81
MAPK_Cascade_h
GO
H000029_01
Info
Mitogen-activated protein kinase kinase kinase 3
H000029_01
U78876
29282
MAP3K3
MAPKinase Signaling Pathway, Phosphatidylinositol signaling system
0.2027051
1.138
82
MAPK_Cascade_h
GO
H002943_01
Info
V-raf murine sarcoma viral oncogene homolog B1
H002943_01
M95712
622
BRAF
MAPKinase Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction, tsonc
0.2376595
0.895
83
MAPK_Cascade_h
GO
H003309_01
Info
Mitogen-activated protein kinase kinase 7
H003309_01
AF013589
110299
MAP2K7
Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAPKinase Signaling Pathway
0.3044184
1.088
84
MAPK_Cascade_h
GO
H002722_01
Info
Mitogen-activated protein kinase kinase 1
H002722_01
L11284
3446
MAP2K1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...
0.7377933
0.973
85
radiation_sensitivity_h
BioCarta
H001935_01
Info
Glyceraldehyde-3-phosphate dehydrogenase
H001935_01
U34995
169476
GAPD

0.0001082
1.485
86
radiation_sensitivity_h
BioCarta
H002040_01
Info
Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)
H002040_01
X00588
77432
EGFR
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degredation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc
0.0004362
0.669
87
radiation_sensitivity_h
BioCarta
H003112_01
Info
Retinoblastoma 1 (including osteosarcoma)
H003112_01
L41870
75770
RB1
BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc
0.0008596
0.674
88
radiation_sensitivity_h
BioCarta
H002681_01
Info
Cyclin D3
H002681_01
M92287
83173
CCND3
Cyclins and Cell Cycle Regulation, cell_cycle
0.0084801
1.28
89
radiation_sensitivity_h
BioCarta
H002092_01
Info
Ataxia telangiectasia and Rad3 related
H002092_01
U49844
77613
ATR
Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Regulation of cell cycle progression by Plk3, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Phosphatidylinositol signaling system, DNA_replication, immunology
0.0105491
0.753
90
radiation_sensitivity_h
BioCarta
H003739_01
Info
Cell division cycle 2, G1 to S and G2 to M
H003739_01
X05360
184572
CDC2
Activation of Src by Protein-tyrosine phosphatase alpha, AKAP95 role in mitosis and chromosome dynamics, cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, How Progesterone Initiates the Oocyte Maturation, Protein Kinase A at the Centrosome, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of Splicing through Sam68, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, Stathmin and breast cancer resistance to antimicrotubule agents, Phosphatidylinositol signaling system, cell_cycle
0.0222229
0.733
91
radiation_sensitivity_h
BioCarta
H002789_01
Info
Tumor protein p53 (Li-Fraumeni syndrome)
H002789_01
NM_000546
1846
TP53
Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc
0.0273242
1.207
92
radiation_sensitivity_h
BioCarta
H002149_01
Info
Cyclin-dependent kinase inhibitor 1A (p21, Cip1)
H002149_01
U03106
179665
CDKN1A
ATM Signaling Pathway, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, Effects of calcineurin in Keratinocyte Differentiation, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia and p53 in the Cardiovascular system, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, immunology, tsonc
0.0349766
1.236
93
radiation_sensitivity_h
BioCarta
H002473_01
Info
Insulin-like growth factor 1 receptor
H002473_01
NM_000875
239176
IGF1R
Perou's- Intrinsic- Breast-Cancer-Genes, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Erk1/Erk2 Mapk Signaling pathway, IGF-1 Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Telomeres, Telomerase, Cellular Aging, and Immortality, The IGF-1 Receptor and Longevity, immunology
0.079692
1.158
94
radiation_sensitivity_h
BioCarta
H002987_01
Info
Cyclin B2
H002987_01
AK001404
194698
CCNB2
Estrogen-responsive protein Efp controls cell cycle and breast tumors growth
0.0829851
0.84
95
radiation_sensitivity_h
BioCarta
H002323_01
Info
Cyclin E1
H002323_01
M74093
9700
CCNE1
Perou's- Intrinsic- Breast-Cancer-Genes, CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression, cell_cycle
0.1107382
0.884
96
radiation_sensitivity_h
BioCarta
H002760_01
Info
RAD51 (S. cerevisiae) homolog (E coli RecA homolog)
H002760_01
D14134
23044
RAD51
ATM Signaling Pathway, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, DNA_damage, DNA_replication
0.1212274
1.154
97
radiation_sensitivity_h
BioCarta
H003605_01
Info
BCL2-associated X protein
H003605_01
L22474
159428
BAX
Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology
0.253339
0.907
98
radiation_sensitivity_h
BioCarta
H003644_01
Info
Tumor necrosis factor receptor superfamily, member 6
H003644_01
X63717
82359
TNFRSF6
apoptosis, immunology
0.4621499
0.927
99
radiation_sensitivity_h
BioCarta
H003538_01
Info
Actin, beta
H003538_01
NM_001101
288061
ACTB
Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes
0.6253266
0.956
100
radiation_sensitivity_h
BioCarta
H003542_01
Info
V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene
H003542_01
M11730
323910
ERBB2
Perou's- Intrinsic- Breast-Cancer-Genes, Role of ERBB2 in Signal Transduction and Oncology, Trefoil Factors Initiate Mucosal Healing, immunology, signal_transduction, tsonc
0.7160857
1.031
101
radiation_sensitivity_h
BioCarta
H006841_01
Info
Homo sapiens mRNA; cDNA DKFZp564P073 (from clone DKFZp564P073)
H006841_01
AL049301
278577

Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology
0.7810094
0.98
102
radiation_sensitivity_h
BioCarta
H003766_01
Info
Mouse double minute 2, human homolog of; p53-binding protein
H003766_01
M92424
170027
MDM2
ATM Signaling Pathway, Cell Cycle: G2/M Checkpoint, CTCF: First Multivalent Nuclear Factor, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Sumoylation by RanBP2 Regulates Transcriptional Repression, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, gene_regulation, transcription, tsonc
0.8018001
0.978
103
radiation_sensitivity_h
BioCarta
H003816_01
Info
Caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase)
H003816_01
M87507
2490
CASP1
Caspase Cascade in Apoptosis, D4-GDI Signaling Pathway, IL 18 Signaling Pathway, apoptosis, immunology
0.9157209
1.011
104
radiation_sensitivity_h
BioCarta
H003027_01
Info
Cyclin D2
H003027_01
D13639
75586
CCND2
Cyclins and Cell Cycle Regulation, cell_cycle
0.9682473
0.996
105
insulinPathway_h
BioCarta
H000732_01
Info
Insulin receptor substrate 1
H000732_01
S62539
96063
IRS1
Perou's- Intrinsic- Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology
0.0013348
0.643
106
insulinPathway_h
BioCarta
H002186_01
Info
Serum response factor (c-fos serum response element-binding transcription factor)
H002186_01
J03161
155321
SRF
EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription
0.0017465
0.722
107
insulinPathway_h
BioCarta
H002055_01
Info
Growth factor receptor-bound protein 2
H002055_01
M96995
296381
GRB2
Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...
0.0022348
1.459
108
insulinPathway_h
BioCarta
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
109
insulinPathway_h
BioCarta
H003178_01
Info
Mitogen-activated protein kinase 3
H003178_01
X60188
861
MAPK3
Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...
0.0986041
1.184
110
insulinPathway_h
BioCarta
H001600_01
Info
RAS p21 protein activator (GTPase activating protein) 1
H001600_01
M23379
758
RASA1
EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction
0.1015906
0.844
111
insulinPathway_h
BioCarta
H003158_01
Info
Mitogen-activated protein kinase 8
H003158_01
L26318
190913
MAPK8
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...
0.1287835
1.166
112
insulinPathway_h
BioCarta
H002624_01
Info
Insulin receptor
H002624_01
X02160
89695
INSR
Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Growth Hormone Signaling Pathway, Insulin Signaling Pathway, immunology
0.433218
0.919
113
insulinPathway_h
BioCarta
H002722_01
Info
Mitogen-activated protein kinase kinase 1
H002722_01
L11284
3446
MAP2K1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...
0.7377933
0.973
114
cellcyclePathway_h
Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.
H003112_01
Info
Retinoblastoma 1 (including osteosarcoma)
H003112_01
L41870
75770
RB1
BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc
0.0008596
0.674
115
cellcyclePathway_h
Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.
H002412_01
Info
Cyclin-dependent kinase 2
H002412_01
M68520
19192
CDK2
CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, immunology, signal_transduction
0.0040171
0.711
116
cellcyclePathway_h
Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.
H002681_01
Info
Cyclin D3
H002681_01
M92287
83173
CCND3
Cyclins and Cell Cycle Regulation, cell_cycle
0.0084801
1.28
117
cellcyclePathway_h
Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.
H000136_01
Info
Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
H000136_01
AF041248
4854
CDKN2C
Cyclins and Cell Cycle Regulation, immunology
0.0088074
0.705
118
cellcyclePathway_h
Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.
H005436_01
Info
Homo sapiens cDNA FLJ20653 fis, clone KAT01739
H005436_01
AK000660
180059

Perou's- Intrinsic- Breast-Cancer-Genes, Cell Cycle: G1/S Check Point , Cyclins and Cell Cycle Regulation, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Influence of Ras and Rho proteins on G1 to S Transition, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction
0.0126769
0.793
119
cellcyclePathway_h
Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.
H003739_01
Info
Cell division cycle 2, G1 to S and G2 to M
H003739_01
X05360
184572
CDC2
Activation of Src by Protein-tyrosine phosphatase alpha, AKAP95 role in mitosis and chromosome dynamics, cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, How Progesterone Initiates the Oocyte Maturation, Protein Kinase A at the Centrosome, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of Splicing through Sam68, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, Stathmin and breast cancer resistance to antimicrotubule agents, Phosphatidylinositol signaling system, cell_cycle
0.0222229
0.733
120
cellcyclePathway_h
Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.
H003410_01
Info
Cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
H003410_01
U26727
1174
CDKN2A
Cell Cycle: G1/S Check Point , CTCF: First Multivalent Nuclear Factor, Cyclins and Cell Cycle Regulation, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc
0.0245577
0.782
121
cellcyclePathway_h
Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.
H003759_01
Info
Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
H003759_01
U40343
29656
CDKN2D
Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation
0.0311312
1.253
122
cellcyclePathway_h
Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.
H002149_01
Info
Cyclin-dependent kinase inhibitor 1A (p21, Cip1)
H002149_01
U03106
179665
CDKN1A
ATM Signaling Pathway, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, Effects of calcineurin in Keratinocyte Differentiation, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia and p53 in the Cardiovascular system, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, immunology, tsonc
0.0349766
1.236
123
cellcyclePathway_h
Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.
H002371_01
Info
Cyclin B1
H002371_01
M25753
23960
CCNB1
Activation of Src by Protein-tyrosine phosphatase alpha, AKAP95 role in mitosis and chromosome dynamics, Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, How Progesterone Initiates the Oocyte Maturation, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, Stathmin and breast cancer resistance to antimicrotubule agents, cell_cycle
0.037756
0.797
124
cellcyclePathway_h
Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.
H002323_01
Info
Cyclin E1
H002323_01
M74093
9700
CCNE1
Perou's- Intrinsic- Breast-Cancer-Genes, CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression, cell_cycle
0.1107382
0.884
125
cellcyclePathway_h
Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.
H001999_01
Info
Cyclin D1 (PRAD1: parathyroid adenomatosis 1)
H001999_01
X59798
82932
CCND1
Perou's- Intrinsic- Breast-Cancer-Genes, BTG family proteins and cell cycle regulation, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G1/S Check Point , Cyclins and Cell Cycle Regulation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, WNT Signaling Pathway, cell_cycle, tsonc
0.3215316
0.898
126
cellcyclePathway_h
Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.
H003750_01
Info
Cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
H003750_01
AF004819
72901
CDKN2B
Cell Cycle: G1/S Check Point , Cyclins and Cell Cycle Regulation, cell_cycle, cell_signaling, signal_transduction, tsonc
0.3235256
0.886
127
cellcyclePathway_h
Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.
H000126_01
Info
Retinoblastoma-like 1 (p107)
H000126_01
L14812
87
RBL1
Cyclins and Cell Cycle Regulation, METS affect on Macrophage Differentiation, cell_cycle
0.4736162
1.053
128
cellcyclePathway_h
Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.
H003162_01
Info
Transcription factor Dp-1
H003162_01
L23959
279576
TFDP1
Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, Regulation of p27 Phosphorylation during Cell Cycle Progression
0.6646128
0.958
129
cellcyclePathway_h
Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.
H002606_01
Info
Cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase)
H002606_01
L20320
184298
CDK7
Perou's- Intrinsic- Breast-Cancer-Genes, Cyclins and Cell Cycle Regulation, Degradation of the RAR and RXR by the proteasome, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction
0.9364784
0.991
130
cellcyclePathway_h
Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.
H003027_01
Info
Cyclin D2
H003027_01
D13639
75586
CCND2
Cyclins and Cell Cycle Regulation, cell_cycle
0.9682473
0.996
131
HOXA9_DOWN_h
Dorsam_et_al_2004
H003124_01
Info
Fc fragment of IgG, receptor, transporter, alpha
H003124_01
U12255
111903
FCGRT

2.86e-05
1.917
132
HOXA9_DOWN_h
Dorsam_et_al_2004
H000825_01
Info
S100 calcium-binding protein A8 (calgranulin A)
H000825_01
X06234
100000
S100A8
immunology
0.0001788
2.746
133
HOXA9_DOWN_h
Dorsam_et_al_2004
H002406_01
Info
Jun B proto-oncogene
H002406_01
X51345
198951
JUNB
GATA3 participate in activating the Th2 cytokine genes expression, tsonc
0.0021761
1.408
134
HOXA9_DOWN_h
Dorsam_et_al_2004
H002878_01
Info
V-yes-1 Yamaguchi sarcoma viral related oncogene homolog
H002878_01
M16038
80887
LYN
BCR Signaling Pathway, Eph Kinases and ephrins support platelet aggregation, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., immunology, signal_transduction, tsonc
0.0068841
1.545
135
HOXA9_DOWN_h
Dorsam_et_al_2004
H000316_01
Info
Delta sleep inducing peptide, immunoreactor
H000316_01
AL110191
75450
DSIPI

0.0102545
1.531
136
HOXA9_DOWN_h
Dorsam_et_al_2004
H006355_01
Info
KIAA1451 protein
H006355_01
AL049923
109694
KIAA1451

0.0105169
1.369
137
HOXA9_DOWN_h
Dorsam_et_al_2004
H000199_01
Info
Translocated promoter region (to activated MET oncogene)
H000199_01
X66397
169750
TPR
tsonc
0.036441
0.801
138
HOXA9_DOWN_h
Dorsam_et_al_2004
H001971_01
Info
Retinoblastoma-binding protein 6
H001971_01
X85133
85273
RBBP6

0.0366619
0.747
139
HOXA9_DOWN_h
Dorsam_et_al_2004
H006255_01
Info
Syndecan binding protein (syntenin)
H006255_01
AF000652
8180
SDCBP

0.0567867
1.234
140
HOXA9_DOWN_h
Dorsam_et_al_2004
H002168_01
Info
GATA-binding protein 2
H002168_01
M68891
760
GATA2
gene_regulation, misc, transcription
0.0841754
0.806
141
HOXA9_DOWN_h
Dorsam_et_al_2004
H004936_01
Info
DKFZP564A122 protein
H004936_01
AL110269
187991
DKFZP564A122

0.0852946
1.175
142
HOXA9_DOWN_h
Dorsam_et_al_2004
H007504_01
Info
Hemoglobin, epsilon 1
H007504_01
NM_005330
117848
HBE1

0.118007
0.749
143
HOXA9_DOWN_h
Dorsam_et_al_2004
H002091_01
Info
V-myc avian myelocytomatosis viral oncogene homolog
H002091_01
K02276
79070
MYC
Cadmium induces DNA synthesis and proliferation in macrophages, CTCF: First Multivalent Nuclear Factor, Erk1/Erk2 Mapk Signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, MAPKinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, WNT Signaling Pathway, gene_regulation, immunology, transcription, tsonc
0.1797519
0.824
144
HOXA9_DOWN_h
Dorsam_et_al_2004
H001023_01
Info
Mannosidase, alpha, class 2A, member 2
H001023_01
L28821
295605
MAN2A2
ERľassociated degradation (ERAD) Pathway, Steps in the Glycosylation of Mammalian N-linked Oligosaccarides, N-Glycan biosynthesis
0.2111813
1.139
145
HOXA9_DOWN_h
Dorsam_et_al_2004
H003255_01
Info
CDC37 (cell division cycle 37, S. cerevisiae, homolog)
H003255_01
U43077
160958
CDC37

0.2178008
0.878
146
HOXA9_DOWN_h
Dorsam_et_al_2004
H000068_01
Info
Signal recognition particle 72kD
H000068_01
AF069765
237825
SRP72
Perou's- Intrinsic- Breast-Cancer-Genes
0.2609516
0.897
147
HOXA9_DOWN_h
Dorsam_et_al_2004
H012741_01
Info
Glutaredoxin (thioltransferase)
H012741_01
AF069668
28988
GLRX
pharmacology
0.2704585
1.145
148
HOXA9_DOWN_h
Dorsam_et_al_2004
H006807_01
Info
Cytokine inducible SH2-containing protein
H006807_01
AF132297
8257
CISH
Growth Hormone Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, immunology
0.3746206
0.888
149
HOXA9_DOWN_h
Dorsam_et_al_2004
H004864_01
Info
Ubiquitin specific protease 1
H004864_01
AF117386
35086
USP1

0.3871195
0.908
150
HOXA9_DOWN_h
Dorsam_et_al_2004
H006584_01
Info
Splicing factor, arginine/serine-rich 11
H006584_01
M74002
11482
SFRS11

0.4576641
1.062
151
HOXA9_DOWN_h
Dorsam_et_al_2004
H010826_01
Info
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
H010826_01
AB024334
25001
YWHAG

0.6175419
1.047
152
HOXA9_DOWN_h
Dorsam_et_al_2004
H016588_01
Info
Hypothetical protein DKFZp761B2423
H016588_01
AK026954
91065
DKFZp761B2423

0.6339659
1.046
153
HOXA9_DOWN_h
Dorsam_et_al_2004
H010792_01
Info
Dynein, cytoplasmic, light intermediate polypeptide 2
H010792_01
AF035812
194625
DNCLI2

0.6511108
1.058
154
HOXA9_DOWN_h
Dorsam_et_al_2004
H002850_01
Info
Murine leukemia viral (bmi-1) oncogene homolog
H002850_01
L13689
431
BMI1
Perou's- Intrinsic- Breast-Cancer-Genes, The PRC2 Complex Sets Long-term Gene Silencing Through Modification of Histone Tails, immunology, tsonc
0.7846354
0.976
155
HOXA9_DOWN_h
Dorsam_et_al_2004
H003618_01
Info
Dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)
H003618_01
D17547
301865
DCT
Tyrosine metabolism
0.9648525
0.996
156
gata3Pathway_h
BioCarta
H003200_01
Info
Mitogen-activated protein kinase kinase 3
H003200_01
D87116
180533
MAP2K3
fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway
0.0009666
1.561
157
gata3Pathway_h
BioCarta
H002406_01
Info
Jun B proto-oncogene
H002406_01
X51345
198951
JUNB
GATA3 participate in activating the Th2 cytokine genes expression, tsonc
0.0021761
1.408
158
gata3Pathway_h
BioCarta
H003415_01
Info
Protein kinase, cAMP-dependent, catalytic, beta
H003415_01
M34181
87773
PRKACB
Perou's- Intrinsic- Breast-Cancer-Genes, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction
0.0048904
0.647
159
gata3Pathway_h
BioCarta
H002895_01
Info
Mitogen-activated protein kinase 14
H002895_01
L35263
79107
MAPK14
BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAPKinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm ...
0.0086925
1.429
160
gata3Pathway_h
BioCarta
H006601_01
Info
V-maf musculoaponeurotic fibrosarcoma (avian) oncogene homolog
H006601_01
AF055376
30250
MAF
GATA3 participate in activating the Th2 cytokine genes expression, tsonc
0.079493
0.812
161
gata3Pathway_h
BioCarta
H001698_01
Info
Protein kinase, cAMP-dependent, regulatory, type II, alpha
H001698_01
X14968
289075
PRKAR2A
AKAP95 role in mitosis and chromosome dynamics, Protein Kinase A at the Centrosome, Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation
0.2569617
1.125
162
gata3Pathway_h
BioCarta
H000645_01
Info
Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
H000645_01
M33336
183037
PRKAR1A
Activation of cAMP-dependent protein kinase, PKA, cell_cycle, cell_signaling, signal_transduction
0.4305614
0.935
163
gata3Pathway_h
BioCarta
H002045_01
Info
Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
H002045_01
U80917
96149
NFATC1
BCR Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Effects of calcineurin in Keratinocyte Differentiation, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Role of MEF2D in T-cell Apoptosis, Signaling Pathway from G-Protein Families, T Cell Receptor Signaling Pathway, immunology
0.623508
1.051
164
ctla4Pathway_h
T cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APCs CD80 or 86.
H001032_01
Info
Cytotoxic T-lymphocyte-associated protein 4
H001032_01
L15006
247824
CTLA4
The Co-Stimulatory Signal During T-cell Activation, immunology
0.0001134
0.56
165
ctla4Pathway_h
T cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APCs CD80 or 86.
H002055_01
Info
Growth factor receptor-bound protein 2
H002055_01
M96995
296381
GRB2
Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...
0.0022348
1.459
166
ctla4Pathway_h
T cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APCs CD80 or 86.
H001210_01
Info
Major histocompatibility complex, class II, DR beta 3
H001210_01
V00522
279930
HLA-DRB3
Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, Antigen Dependent B Cell Activation, Antigen Processing and Presentation, B Lymphocyte Cell Surface Molecules, Bystander B Cell Activation, Cytokines and Inflammatory Response, IL 5 Signaling Pathway, Lck and Fyn tyrosine kinases in initiation of TCR Activation, Th1/Th2 Differentiation, The Co-Stimulatory Signal During T-cell Activation, The Role of Eosinophils in the Chemokine Network of Allergy, immunology
0.0031398
1.8
167
ctla4Pathway_h
T cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APCs CD80 or 86.
H003054_01
Info
Major histocompatibility complex, class II, DR alpha
H003054_01
J00194
76807
HLA-DRA
Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, Antigen Dependent B Cell Activation, Antigen Processing and Presentation, B Lymphocyte Cell Surface Molecules, Bystander B Cell Activation, Cytokines and Inflammatory Response, IL 5 Signaling Pathway, Lck and Fyn tyrosine kinases in initiation of TCR Activation, Th1/Th2 Differentiation, The Co-Stimulatory Signal During T-cell Activation, The Role of Eosinophils in the Chemokine Network of Allergy, immunology
0.0045394
1.755
168
ctla4Pathway_h
T cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APCs CD80 or 86.
H002284_01
Info
Major histocompatibility complex, class II, DR beta 5
H002284_01
M20430
308026
HLA-DRB5
Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, Antigen Dependent B Cell Activation, Antigen Processing and Presentation, B Lymphocyte Cell Surface Molecules, Bystander B Cell Activation, Cytokines and Inflammatory Response, IL 5 Signaling Pathway, Lck and Fyn tyrosine kinases in initiation of TCR Activation, Th1/Th2 Differentiation, The Co-Stimulatory Signal During T-cell Activation, The Role of Eosinophils in the Chemokine Network of Allergy, immunology
0.0670054
1.503
169
ctla4Pathway_h
T cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APCs CD80 or 86.
H015660_01
Info
Major histocompatibility complex, class II, DR beta 4
H015660_01
NM_021983
293934
HLA-DRB4
Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, Antigen Dependent B Cell Activation, Antigen Processing and Presentation, B Lymphocyte Cell Surface Molecules, Bystander B Cell Activation, Cytokines and Inflammatory Response, IL 5 Signaling Pathway, Lck and Fyn tyrosine kinases in initiation of TCR Activation, Th1/Th2 Differentiation, The Co-Stimulatory Signal During T-cell Activation, The Role of Eosinophils in the Chemokine Network of Allergy, immunology
0.2187912
0.885
170
ctla4Pathway_h
T cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APCs CD80 or 86.
H003820_01
Info
Lymphocyte-specific protein tyrosine kinase
H003820_01
X05027
1765
LCK
Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, IL 2 signaling pathway, IL-7 Signal Transduction, Lck and Fyn tyrosine kinases in initiation of TCR Activation, T Cell Receptor Signaling Pathway, The Co-Stimulatory Signal During T-cell Activation, immunology, signal_transduction, tsonc
0.2266863
0.873
171
ctla4Pathway_h
T cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APCs CD80 or 86.
H000858_01
Info
Homo sapiens, clone MGC:12387, mRNA, complete cds
H000858_01
M16942
318720

Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, Antigen Dependent B Cell Activation, Antigen Processing and Presentation, B Lymphocyte Cell Surface Molecules, Bystander B Cell Activation, Cytokines and Inflammatory Response, IL 5 Signaling Pathway, Lck and Fyn tyrosine kinases in initiation of TCR Activation, Th1/Th2 Differentiation, The Co-Stimulatory Signal During T-cell Activation, The Role of Eosinophils in the Chemokine Network of Allergy, immunology
0.2327988
1.274
172
ctla4Pathway_h
T cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APCs CD80 or 86.
H001197_01
Info
T cell receptor beta locus
H001197_01
X00437
303157
TRB@

0.4180662
0.913
173
ctla4Pathway_h
T cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APCs CD80 or 86.
H002570_01
Info
Interleukin 2
H002570_01
S82692
89679
IL2
Antigen Dependent B Cell Activation, Cytokine Network, Cytokines and Inflammatory Response, IL 18 Signaling Pathway, IL 2 signaling pathway, OX40 Signaling Pathway, Regulation of hematopoiesis by cytokines, Role of Tob in T-cell activation, Selective expression of chemokine receptors during T-cell polarization, Th1/Th2 Differentiation, The 4-1BB-dependent immune response, The Co-Stimulatory Signal During T-cell Activation, immunology
0.6483346
1.043
174
ctla4Pathway_h
T cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APCs CD80 or 86.
H001267_01
Info
CD3Z antigen, zeta polypeptide (TiT3 complex)
H001267_01
NM_000734
97087
CD3Z
immunology
0.8300402
1.024
175
cell_cycle_checkpointII_h
GO
H003112_01
Info
Retinoblastoma 1 (including osteosarcoma)
H003112_01
L41870
75770
RB1
BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc
0.0008596
0.674
176
cell_cycle_checkpointII_h
GO
H001983_01
Info
Fanconi anemia, complementation group G
H001983_01
AJ007669
8047
FANCG
BRCA1-dependent Ub-ligase activity, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, DNA_damage, immunology
0.0098981
0.692
177
cell_cycle_checkpointII_h
GO
H002092_01
Info
Ataxia telangiectasia and Rad3 related
H002092_01
U49844
77613
ATR
Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Regulation of cell cycle progression by Plk3, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Phosphatidylinositol signaling system, DNA_replication, immunology
0.0105491
0.753
178
cell_cycle_checkpointII_h
GO
H003410_01
Info
Cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
H003410_01
U26727
1174
CDKN2A
Cell Cycle: G1/S Check Point , CTCF: First Multivalent Nuclear Factor, Cyclins and Cell Cycle Regulation, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc
0.0245577
0.782
179
cell_cycle_checkpointII_h
GO
H002789_01
Info
Tumor protein p53 (Li-Fraumeni syndrome)
H002789_01
NM_000546
1846
TP53
Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc
0.0273242
1.207
180
cell_cycle_checkpointII_h
GO
H001967_01
Info
Cyclin E2
H001967_01
AF091433
30464
CCNE2
cell_cycle
0.0814824
0.826
181
cell_cycle_checkpointII_h
GO
H002232_01
Info
Cell division cycle 34
H002232_01
L22005
76932
CDC34
Cell Cycle: G2/M Checkpoint, Cyclin E Destruction Pathway, E2F1 Destruction Pathway, Ubiquitin mediated proteolysis
0.8799021
0.983
182
g1Pathway_h
BioCarta
H003112_01
Info
Retinoblastoma 1 (including osteosarcoma)
H003112_01
L41870
75770
RB1
BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc
0.0008596
0.674
183
g1Pathway_h
BioCarta
H002412_01
Info
Cyclin-dependent kinase 2
H002412_01
M68520
19192
CDK2
CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, immunology, signal_transduction
0.0040171
0.711
184
g1Pathway_h
BioCarta
H002092_01
Info
Ataxia telangiectasia and Rad3 related
H002092_01
U49844
77613
ATR
Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Regulation of cell cycle progression by Plk3, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Phosphatidylinositol signaling system, DNA_replication, immunology
0.0105491
0.753
185
g1Pathway_h
BioCarta
H005436_01
Info
Homo sapiens cDNA FLJ20653 fis, clone KAT01739
H005436_01
AK000660
180059

Perou's- Intrinsic- Breast-Cancer-Genes, Cell Cycle: G1/S Check Point , Cyclins and Cell Cycle Regulation, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Influence of Ras and Rho proteins on G1 to S Transition, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction
0.0126769
0.793
186
g1Pathway_h
BioCarta
H003739_01
Info
Cell division cycle 2, G1 to S and G2 to M
H003739_01
X05360
184572
CDC2
Activation of Src by Protein-tyrosine phosphatase alpha, AKAP95 role in mitosis and chromosome dynamics, cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, How Progesterone Initiates the Oocyte Maturation, Protein Kinase A at the Centrosome, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of Splicing through Sam68, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, Stathmin and breast cancer resistance to antimicrotubule agents, Phosphatidylinositol signaling system, cell_cycle
0.0222229
0.733
187
g1Pathway_h
BioCarta
H003410_01
Info
Cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
H003410_01
U26727
1174
CDKN2A
Cell Cycle: G1/S Check Point , CTCF: First Multivalent Nuclear Factor, Cyclins and Cell Cycle Regulation, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc
0.0245577
0.782
188
g1Pathway_h
BioCarta
H002789_01
Info
Tumor protein p53 (Li-Fraumeni syndrome)
H002789_01
NM_000546
1846
TP53
Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc
0.0273242
1.207
189
g1Pathway_h
BioCarta
H002149_01
Info
Cyclin-dependent kinase inhibitor 1A (p21, Cip1)
H002149_01
U03106
179665
CDKN1A
ATM Signaling Pathway, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, Effects of calcineurin in Keratinocyte Differentiation, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia and p53 in the Cardiovascular system, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, immunology, tsonc
0.0349766
1.236
190
g1Pathway_h
BioCarta
H002323_01
Info
Cyclin E1
H002323_01
M74093
9700
CCNE1
Perou's- Intrinsic- Breast-Cancer-Genes, CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression, cell_cycle
0.1107382
0.884
191
g1Pathway_h
BioCarta
H003207_01
Info
V-abl Abelson murine leukemia viral oncogene homolog 1
H003207_01
NM_005157
146355
ABL1
cell_signaling, signal_transduction, tsonc
0.1292454
0.826
192
g1Pathway_h
BioCarta
H003023_01
Info
Dihydrofolate reductase
H003023_01
NM_000791
83765
DHFR
Cell Cycle: G1/S Check Point , Folate biosynthesis, One carbon pool by folate, immunology, pharmacology
0.1336155
0.862
193
g1Pathway_h
BioCarta
H001999_01
Info
Cyclin D1 (PRAD1: parathyroid adenomatosis 1)
H001999_01
X59798
82932
CCND1
Perou's- Intrinsic- Breast-Cancer-Genes, BTG family proteins and cell cycle regulation, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G1/S Check Point , Cyclins and Cell Cycle Regulation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, WNT Signaling Pathway, cell_cycle, tsonc
0.3215316
0.898
194
g1Pathway_h
BioCarta
H003750_01
Info
Cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
H003750_01
AF004819
72901
CDKN2B
Cell Cycle: G1/S Check Point , Cyclins and Cell Cycle Regulation, cell_cycle, cell_signaling, signal_transduction, tsonc
0.3235256
0.886
195
g1Pathway_h
BioCarta
H009086_01
Info
S-phase kinase-associated protein 2 (p45)
H009086_01
U33761
23348
SKP2
Cell Cycle: G1/S Check Point , E2F1 Destruction Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression
0.330649
1.089
196
g1Pathway_h
BioCarta
H000650_01
Info
Glycogen synthase kinase 3 beta
H000650_01
L33801
78802
GSK3B
ALK in cardiac myocytes, Cell Cycle: G1/S Check Point , Deregulation of CDK5 in Alzheimers Disease, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Presenilin action in Notch and Wnt signaling, Regulation of eIF2, Segmentation Clock, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Sonic Hedgehog (Shh) Pathway, WNT Signaling Pathway, Phosphatidylinositol signaling system
0.353328
1.118
197
g1Pathway_h
BioCarta
H003162_01
Info
Transcription factor Dp-1
H003162_01
L23959
279576
TFDP1
Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, Regulation of p27 Phosphorylation during Cell Cycle Progression
0.6646128
0.958
198
g1Pathway_h
BioCarta
H000578_01
Info
Histone deacetylase 1
H000578_01
D50405
88556
HDAC1
immunology
0.8155423
1.017
199
EMT_UP_h
Jechlinger_et_al_2003
H003225_01
Info
Interferon regulatory factor 7
H003225_01
AF076494
166120
IRF7
gene_regulation, transcription
6.44e-05
1.728
200
EMT_UP_h
Jechlinger_et_al_2003
H000825_01
Info
S100 calcium-binding protein A8 (calgranulin A)
H000825_01
X06234
100000
S100A8
immunology
0.0001788
2.746
201
EMT_UP_h
Jechlinger_et_al_2003
H001850_01
Info
Interferon-stimulated protein, 15 kDa
H001850_01
M13755
833
ISG15

0.0003862
1.943
202
EMT_UP_h
Jechlinger_et_al_2003
H000473_01
Info
Uridine phosphorylase
H000473_01
X90858
77573
UP
Pyrimidine metabolism
0.0005102
1.339
203
EMT_UP_h
Jechlinger_et_al_2003
H002726_01
Info
B-cell CLL/lymphoma 3
H002726_01
M31732
31210
BCL3
tsonc
0.0147426
1.351
204
EMT_UP_h
Jechlinger_et_al_2003
H003466_01
Info
CD68 antigen
H003466_01
S57235
246381
CD68
angiogenesis, immunology, metastasis
0.0179458
1.335
205
EMT_UP_h
Jechlinger_et_al_2003
H003299_01
Info
Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
H003299_01
M59979
88474
PTGS1
Aspirin Blocks Signaling Pathway Involved in Platelet Activation, Eicosanoid Metabolism, Mechanism of Acetaminophen Activity and Toxicity, Prostaglandin and leukotriene metabolism, immunology
0.023304
0.813
206
EMT_UP_h
Jechlinger_et_al_2003
H003029_01
Info
Disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein)
H003029_01
U53446
81988
DAB2

0.0291633
0.78
207
EMT_UP_h
Jechlinger_et_al_2003
H003752_01
Info
Platelet-derived growth factor receptor, beta polypeptide
H003752_01
J03278
76144
PDGFRB
cell_cycle, cell_signaling, immunology, misc, signal_transduction
0.0333891
0.832
208
EMT_UP_h
Jechlinger_et_al_2003
H006885_01
Info
Ribonuclease 6 precursor
H006885_01
NM_003730
8297
RNASE6PL

0.0955467
1.208
209
EMT_UP_h
Jechlinger_et_al_2003
H000998_01
Info
Solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
H000998_01
AB018010
79748
SLC3A2
Perou's- Intrinsic- Breast-Cancer-Genes
0.1156436
0.843
210
EMT_UP_h
Jechlinger_et_al_2003
H001908_01
Info
Discoidin domain receptor family, member 2
H001908_01
X74764
71891
DDR2

0.1167676
0.839
211
EMT_UP_h
Jechlinger_et_al_2003
H001001_01
Info
Procollagen C-endopeptidase enhancer
H001001_01
NM_002593
202097
PCOLCE

0.1228497
0.868
212
EMT_UP_h
Jechlinger_et_al_2003
H000774_01
Info
Collagen, type VI, alpha 1
H000774_01
X15880
108885
COL6A1

0.1448402
0.841
213
EMT_UP_h
Jechlinger_et_al_2003
H002775_01
Info
Platelet-derived growth factor receptor, alpha polypeptide
H002775_01
M21574
74615
PDGFRA
Perou's- Intrinsic- Breast-Cancer-Genes, CBL mediated ligand-induced downregulation of EGF receptors, Erk1/Erk2 Mapk Signaling pathway, PDGF Signaling Pathway, Phospholipids as signalling intermediaries, Rac 1 cell motility signaling pathway, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, immunology, signal_transduction
0.1636921
1.107
214
EMT_UP_h
Jechlinger_et_al_2003
H010646_01
Info
Ribonuclease 6 precursor
H010646_01
AK001769
8297
RNASE6PL

0.1872503
1.127
215
EMT_UP_h
Jechlinger_et_al_2003
H002295_01
Info
Adenosine deaminase
H002295_01
X02994
1217
ADA
Purine metabolism, gene_regulation, immunology, transcription
0.1882263
0.871
216
EMT_UP_h
Jechlinger_et_al_2003
H012626_01
Info
Beta-2-microglobulin
H012626_01
AB021288
75415
B2M
Antigen Processing and Presentation, CTL mediated immune response against target cells , Ras-Independent pathway in NK cell-mediated cytotoxicity, immunology
0.1923361
1.156
217
EMT_UP_h
Jechlinger_et_al_2003
H003645_01
Info
Interleukin 11
H003645_01
X58377
1721
IL11
Cytokines and Inflammatory Response, Erythrocyte Differentiation Pathway, Regulation of hematopoiesis by cytokines, immunology
0.2074062
1.116
218
EMT_UP_h
Jechlinger_et_al_2003
H003593_01
Info
Collagen, type VI, alpha 2
H003593_01
AL096746
159263
COL6A2

0.300891
1.098
219
EMT_UP_h
Jechlinger_et_al_2003
H001198_01
Info
Homo sapiens, alpha-1 (VI) collagen
H001198_01
M20776
25459


0.3632512
1.1
220
EMT_UP_h
Jechlinger_et_al_2003
H002451_01
Info
Flavin containing monooxygenase 1
H002451_01
M64082
1424
FMO1
immunology, misc
0.3681883
0.911
221
EMT_UP_h
Jechlinger_et_al_2003
H000592_01
Info
Interferon-induced protein with tetratricopeptide repeats 1
H000592_01
X03557
20315
IFIT1

0.4335751
1.121
222
EMT_UP_h
Jechlinger_et_al_2003
H002713_01
Info
Phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
H002713_01
U24577
93304
PLA2G7
Glycerophospholipid metabolism
0.4631812
0.89
223
EMT_UP_h
Jechlinger_et_al_2003
H010497_01
Info
Interferon induced transmembrane protein 3 (1-8U)
H010497_01
X57352
182241
IFITM3

0.5875785
1.062
224
EMT_UP_h
Jechlinger_et_al_2003
H003695_01
Info
Secreted protein, acidic, cysteine-rich (osteonectin)
H003695_01
J03040
111779
SPARC
misc
0.6414286
1.051
225
EMT_UP_h
Jechlinger_et_al_2003
H002330_01
Info
Cadherin 15, M-cadherin (myotubule)
H002330_01
D83542
148090
CDH15

0.7996949
0.974
226
EMT_UP_h
Jechlinger_et_al_2003
H002397_01
Info
Methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
H002397_01
X16396
154672
MTHFD2
Glyoxylate and dicarboxylate metabolism, One carbon pool by folate
0.8081788
0.975
227
EMT_UP_h
Jechlinger_et_al_2003
H002672_01
Info
G protein-coupled receptor
H002672_01
U67784
23016
RDC1

0.8527585
0.967
228
EMT_UP_h
Jechlinger_et_al_2003
H002490_01
Info
Hexabrachion (tenascin C, cytotactin)
H002490_01
X78565
289114
HXB
Perou's- Intrinsic- Breast-Cancer-Genes
0.856155
0.983
229
EMT_UP_h
Jechlinger_et_al_2003
H002283_01
Info
Secretory leukocyte protease inhibitor (antileukoproteinase)
H002283_01
X04470
251754
SLPI
Perou's- Intrinsic- Breast-Cancer-Genes, Proepithelin Conversion to Epithelin and Wound Repair Control, immunology
0.9075348
1.012
230
EMT_UP_h
Jechlinger_et_al_2003
H004245_01
Info
Snail 1 (drosophila homolog), zinc finger protein
H004245_01
AF125377
48029
SNAI1
Downregulated of MTA-3 in ER-negative Breast Tumors
0.9743253
1.003
231
tumor_supressor_h
BioCarta
H001935_01
Info
Glyceraldehyde-3-phosphate dehydrogenase
H001935_01
U34995
169476
GAPD

0.0001082
1.485
232
tumor_supressor_h
BioCarta
H003112_01
Info
Retinoblastoma 1 (including osteosarcoma)
H003112_01
L41870
75770
RB1
BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc
0.0008596
0.674
233
tumor_supressor_h
BioCarta
H002387_01
Info
MutS (E. coli) homolog 2 (colon cancer, nonpolyposis type 1)
H002387_01
NM_000251
78934
MSH2
DNA_damage, tsonc
0.004273
0.694
234
tumor_supressor_h
BioCarta
H000570_01
Info
CREB binding protein (Rubinstein-Taybi syndrome)
H000570_01
U47741
23598
CREBBP
gene_regulation, transcription
0.0048718
1.469
235
tumor_supressor_h
BioCarta
H000208_01
Info
Breast cancer 1, early onset
H000208_01
NM_007295
194143
BRCA1
ATM Signaling Pathway, BRCA1-dependent Ub-ligase activity, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, DNA_damage, immunology, tsonc
0.009032
0.746
236
tumor_supressor_h
BioCarta
H002789_01
Info
Tumor protein p53 (Li-Fraumeni syndrome)
H002789_01
NM_000546
1846
TP53
Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc
0.0273242
1.207
237
tumor_supressor_h
BioCarta
H003759_01
Info
Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
H003759_01
U40343
29656
CDKN2D
Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation
0.0311312
1.253
238
tumor_supressor_h
BioCarta
H002114_01
Info
Neurofibromin 2 (bilateral acoustic neuroma)
H002114_01
L11353
902
NF2
immunology, tsonc
0.2904249
0.837
239
tumor_supressor_h
BioCarta
H002700_01
Info
Transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kD)
H002700_01
L11695
220
TGFBR1
ALK in cardiac myocytes, Function of SLRP in Bone: An Integrated View, MAPKinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, p38 MAPK Signaling Pathway , TGF beta signaling pathway, Phosphatidylinositol signaling system, angiogenesis, development
0.3279632
0.903
240
tumor_supressor_h
BioCarta
H002611_01
Info
Interferon regulatory factor 1
H002611_01
X14454
80645
IRF1
gene_regulation, transcription
0.3284273
0.915
241
tumor_supressor_h
BioCarta
H006635_01
Info
Homo sapiens clone 23607 mRNA sequence
H006635_01
AF038181
167825

ALK in cardiac myocytes, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, Presenilin action in Notch and Wnt signaling, TGF beta signaling pathway, WNT Signaling Pathway, development, immunology, tsonc
0.6181322
1.041
242
tumor_supressor_h
BioCarta
H003538_01
Info
Actin, beta
H003538_01
NM_001101
288061
ACTB
Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes
0.6253266
0.956
243
tumor_supressor_h
BioCarta
H007492_01
Info
Cofilin 1 (non-muscle)
H007492_01
X95404
180370
CFL1
CCR3 signaling in Eosinophils, Rac 1 cell motility signaling pathway, Rho cell motility signaling pathway
0.685636
1.038
244
tumor_supressor_h
BioCarta
H003594_01
Info
Cyclin-dependent kinase inhibitor 1C (p57, Kip2)
H003594_01
U22398
106070
CDKN1C
cell_cycle, immunology, tsonc
0.7532847
0.968
245
tumor_supressor_h
BioCarta
H003151_01
Info
E1A binding protein p300
H003151_01
U01877
25272
EP300
Acetylation and Deacetylation of RelA in The Nucleus, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Control of Gene Expression by Vitamin D Receptor, Hypoxia and p53 in the Cardiovascular system, Hypoxia-Inducible Factor in the Cardiovascular System, IL-7 Signal Transduction, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Melanocyte Development and Pigmentation Pathway, Multi-step Regulation of Transcription by Pitx2, NFkB activation by Nontypeable Hemophilus influenzae, Pelp1 Modulation of Estrogen Receptor Activity, Role of ERBB2 in Signal Transduction and Oncology, Role of MEF2D in T-cell Apoptosis, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, TGF beta signaling pathway, Transcription Regulation by Methyltransferase of CARM1, gene_regulation, transcription
0.9607239
1.004
246
drug_resistance_and_metabolism_h
BioCarta
H001935_01
Info
Glyceraldehyde-3-phosphate dehydrogenase
H001935_01
U34995
169476
GAPD

0.0001082
1.485
247
drug_resistance_and_metabolism_h
BioCarta
H002040_01
Info
Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)
H002040_01
X00588
77432
EGFR
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degredation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc
0.0004362
0.669
248
drug_resistance_and_metabolism_h
BioCarta
H003596_01
Info
O-6-methylguanine-DNA methyltransferase
H003596_01
M29971
1384
MGMT
DNA_adducts, DNA_damage
0.0006291
0.667
249
drug_resistance_and_metabolism_h
BioCarta
H003112_01
Info
Retinoblastoma 1 (including osteosarcoma)
H003112_01
L41870
75770
RB1
BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc
0.0008596
0.674
250
drug_resistance_and_metabolism_h
BioCarta
H002412_01
Info
Cyclin-dependent kinase 2
H002412_01
M68520
19192
CDK2
CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, immunology, signal_transduction
0.0040171
0.711
251
drug_resistance_and_metabolism_h
BioCarta
H000872_01
Info
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
H000872_01
AF104942
108660
ABCC5

0.00423
0.773
252
drug_resistance_and_metabolism_h
BioCarta
H002387_01
Info
MutS (E. coli) homolog 2 (colon cancer, nonpolyposis type 1)
H002387_01
NM_000251
78934
MSH2
DNA_damage, tsonc
0.004273
0.694
253
drug_resistance_and_metabolism_h
BioCarta
H000208_01
Info
Breast cancer 1, early onset
H000208_01
NM_007295
194143
BRCA1
ATM Signaling Pathway, BRCA1-dependent Ub-ligase activity, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, DNA_damage, immunology, tsonc
0.009032
0.746
254
drug_resistance_and_metabolism_h
BioCarta
H003606_01
Info
Retinoid X receptor, alpha
H003606_01
U66306
20084
RXRA
Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Control of Gene Expression by Vitamin D Receptor, Degradation of the RAR and RXR by the proteasome, FXR and LXR Regulation of Cholesterol Metabolism, Map Kinase Inactivation of SMRT Corepressor, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, Transcription Regulation by Methyltransferase of CARM1, Visceral Fat Deposits and the Metabolic Syndrome, development, gene_regulation, transcription
0.0142664
1.308
255
drug_resistance_and_metabolism_h
BioCarta
H001848_01
Info
Glutathione S-transferase M1
H001848_01
J03817
324730
GSTM1
Glutathione metabolism, immunology, pharmacology
0.018415
0.773
256
drug_resistance_and_metabolism_h
BioCarta
H003283_01
Info
Topoisomerase (DNA) II alpha (170kD)
H003283_01
J04088
156346
TOP2A
Apoptotic DNA fragmentation and tissue homeostasis, DNA_adducts, DNA_damage, DNA_replication
0.0203748
0.733
257
drug_resistance_and_metabolism_h
BioCarta
H002533_01
Info
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
H002533_01
AF076622
274260
ABCC6

0.0229826
1.478
258
drug_resistance_and_metabolism_h
BioCarta
H003410_01
Info
Cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
H003410_01
U26727
1174
CDKN2A
Cell Cycle: G1/S Check Point , CTCF: First Multivalent Nuclear Factor, Cyclins and Cell Cycle Regulation, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc
0.0245577
0.782
259
drug_resistance_and_metabolism_h
BioCarta
H002789_01
Info
Tumor protein p53 (Li-Fraumeni syndrome)
H002789_01
NM_000546
1846
TP53
Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc
0.0273242
1.207
260
drug_resistance_and_metabolism_h
BioCarta
H003759_01
Info
Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
H003759_01
U40343
29656
CDKN2D
Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation
0.0311312
1.253
261
drug_resistance_and_metabolism_h
BioCarta
H002149_01
Info
Cyclin-dependent kinase inhibitor 1A (p21, Cip1)
H002149_01
U03106
179665
CDKN1A
ATM Signaling Pathway, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, Effects of calcineurin in Keratinocyte Differentiation, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia and p53 in the Cardiovascular system, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, immunology, tsonc
0.0349766
1.236
262
drug_resistance_and_metabolism_h
BioCarta
H002424_01
Info
Bleomycin hydrolase
H002424_01
X92106
78943
BLMH
immunology, pharmacology
0.0414602
0.81
263
drug_resistance_and_metabolism_h
BioCarta
H007820_01
Info
Retinoic acid receptor-beta associated open reading frame
H007820_01
S82362
1938
LOC51036
Control of Gene Expression by Vitamin D Receptor, DNA_adducts, DNA_damage, gene_regulation, transcription
0.0421365
0.794
264
drug_resistance_and_metabolism_h
BioCarta
H003156_01
Info
V-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptid
H003156_01
M83221
858
RELB
tsonc
0.0527226
1.209
265
drug_resistance_and_metabolism_h
BioCarta
H007892_01
Info
Cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19
H007892_01
M61854
198501
CYP2C19
Fatty acid metabolism, gamma-Hexachlorocyclohexane degradation, Tryptophan metabolism, pharmacology
0.0560255
0.801
266
drug_resistance_and_metabolism_h
BioCarta
H003713_01
Info
Topoisomerase (DNA) II beta (180kD)
H003713_01
X68060
75248
TOP2B
Control of Gene Expression by Vitamin D Receptor, DNA_adducts, DNA_damage, gene_regulation, transcription
0.075384
0.83
267
drug_resistance_and_metabolism_h
BioCarta
H002473_01
Info
Insulin-like growth factor 1 receptor
H002473_01
NM_000875
239176
IGF1R
Perou's- Intrinsic- Breast-Cancer-Genes, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Erk1/Erk2 Mapk Signaling pathway, IGF-1 Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Telomeres, Telomerase, Cellular Aging, and Immortality, The IGF-1 Receptor and Longevity, immunology
0.079692
1.158
268
drug_resistance_and_metabolism_h
BioCarta
H003600_01
Info
Epoxide hydrolase 2, cytoplasmic
H003600_01
L05779
113
EPHX2
Tetrachloroethene degradation, immunology, metabolism, pharmacology
0.092835
0.858
269
drug_resistance_and_metabolism_h
BioCarta
H002323_01
Info
Cyclin E1
H002323_01
M74093
9700
CCNE1
Perou's- Intrinsic- Breast-Cancer-Genes, CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression, cell_cycle
0.1107382
0.884
270
drug_resistance_and_metabolism_h
BioCarta
H003376_01
Info
Aryl hydrocarbon receptor nuclear translocator
H003376_01
M69238
166172
ARNT
Ahr Signal Transduction Pathway, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia-Inducible Factor in the Cardiovascular System, VEGF, Hypoxia, and Angiogenesis, angiogenesis, immunology
0.1249479
1.133
271
drug_resistance_and_metabolism_h
BioCarta
H014546_01
Info
Peptidylprolyl isomerase A (cyclophilin A)
H014546_01
NM_021130
182937
PPIA
IL-2 Receptor Beta Chain in T cell Activation
0.129858
1.176
272
drug_resistance_and_metabolism_h
BioCarta
H003023_01
Info
Dihydrofolate reductase
H003023_01
NM_000791
83765
DHFR
Cell Cycle: G1/S Check Point , Folate biosynthesis, One carbon pool by folate, immunology, pharmacology
0.1336155
0.862
273
drug_resistance_and_metabolism_h
BioCarta
H003550_01
Info
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
H003550_01
S76638
73090
NFKB2
gene_regulation, immunology, transcription, tsonc
0.1593331
1.165
274
drug_resistance_and_metabolism_h
BioCarta
H001986_01
Info
Aryl hydrocarbon receptor
H001986_01
NM_001621
170087
AHR
Ahr Signal Transduction Pathway, gene_regulation, immunology, transcription
0.1792938
1.117
275
drug_resistance_and_metabolism_h
BioCarta
H002091_01
Info
V-myc avian myelocytomatosis viral oncogene homolog
H002091_01
K02276
79070
MYC
Cadmium induces DNA synthesis and proliferation in macrophages, CTCF: First Multivalent Nuclear Factor, Erk1/Erk2 Mapk Signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, MAPKinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, WNT Signaling Pathway, gene_regulation, immunology, transcription, tsonc
0.1797519
0.824
276
drug_resistance_and_metabolism_h
BioCarta
H003810_01
Info
Superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))
H003810_01
X02317
75428
SOD1
Cardiac Protection Against ROS , Free Radical Induced Apoptosis, immunology, pharmacology
0.1871555
1.13
277
drug_resistance_and_metabolism_h
BioCarta
H003242_01
Info
Excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pig
H003242_01
M31899
77929
ERCC3
CARM1 and Regulation of the Estrogen Receptor, Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes, Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, DNA_damage, DNA_replication, immunology
0.2157492
0.873
278
drug_resistance_and_metabolism_h
BioCarta
H003042_01
Info
BCL2-like 1
H003042_01
Z23115
305890
BCL2L1
Apoptotic Signaling in Response to DNA Damage, IL-2 Receptor Beta Chain in T cell Activation, Opposing roles of AIF in Apoptosis and Cell Survival, Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, immunology
0.2336065
1.143
279
drug_resistance_and_metabolism_h
BioCarta
H003605_01
Info
BCL2-associated X protein
H003605_01
L22474
159428
BAX
Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology
0.253339
0.907
280
drug_resistance_and_metabolism_h
BioCarta
H003514_01
Info
Cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2
H003514_01
M55053
1361
CYP1A2
Mechanism of Acetaminophen Activity and Toxicity, Nuclear Receptors in Lipid Metabolism and Toxicity, Fatty acid metabolism, gamma-Hexachlorocyclohexane degradation, Tryptophan metabolism, immunology, pharmacology
0.2704204
1.089
281
drug_resistance_and_metabolism_h
BioCarta
H011468_01
Info
ATP-binding cassette, sub-family G (WHITE), member 2
H011468_01
AF103796
194720
ABCG2

0.2713892
0.876
282
drug_resistance_and_metabolism_h
BioCarta
H002577_01
Info
MutL (E. coli) homolog 1 (colon cancer, nonpolyposis type 2)
H002577_01
U07418
57301
MLH1
DNA_damage, DNA_replication, tsonc
0.2947975
0.894
283
drug_resistance_and_metabolism_h
BioCarta
H003016_01
Info
Insulin-like growth factor 2 receptor
H003016_01
Y00285
76473
IGF2R
immunology
0.3174469
1.143
284
drug_resistance_and_metabolism_h
BioCarta
H001999_01
Info
Cyclin D1 (PRAD1: parathyroid adenomatosis 1)
H001999_01
X59798
82932
CCND1
Perou's- Intrinsic- Breast-Cancer-Genes, BTG family proteins and cell cycle regulation, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G1/S Check Point , Cyclins and Cell Cycle Regulation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, WNT Signaling Pathway, cell_cycle, tsonc
0.3215316
0.898
285
drug_resistance_and_metabolism_h
BioCarta
H002702_01
Info
Retinoic acid receptor, gamma
H002702_01
M38258
1497
RARG
Nuclear Receptors in Lipid Metabolism and Toxicity, development, gene_regulation, transcription
0.4297075
1.087
286
drug_resistance_and_metabolism_h
BioCarta
H002294_01
Info
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
H002294_01
X78338
89433
ABCC1
Multi-Drug Resistance Factors
0.4691659
0.928
287
drug_resistance_and_metabolism_h
BioCarta
H002907_01
Info
Retinoic acid receptor, alpha
H002907_01
X06614
250505
RARA
Degradation of the RAR and RXR by the proteasome, Map Kinase Inactivation of SMRT Corepressor, Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, Nuclear Receptors in Lipid Metabolism and Toxicity, Regulation of transcriptional activity by PML, Transcription Regulation by Methyltransferase of CARM1, development
0.4825926
1.084
288
drug_resistance_and_metabolism_h
BioCarta
H000149_01
Info
Epoxide hydrolase 1, microsomal (xenobiotic)
H000149_01
NM_000120
89649
EPHX1
Eicosanoid Metabolism, Tetrachloroethene degradation, immunology, metabolism, pharmacology
0.512274
0.938
289
drug_resistance_and_metabolism_h
BioCarta
H001952_01
Info
Ribosomal protein L13a
H001952_01
X56932
119122
RPL13A

0.565051
1.059
290
drug_resistance_and_metabolism_h
BioCarta
H006635_01
Info
Homo sapiens clone 23607 mRNA sequence
H006635_01
AF038181
167825

ALK in cardiac myocytes, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, Presenilin action in Notch and Wnt signaling, TGF beta signaling pathway, WNT Signaling Pathway, development, immunology, tsonc
0.6181322
1.041
291
drug_resistance_and_metabolism_h
BioCarta
H002777_01
Info
Cytochrome P450, subfamily IIE (ethanol-inducible)
H002777_01
J02625
75183
CYP2E
Mechanism of Acetaminophen Activity and Toxicity, Nuclear Receptors in Lipid Metabolism and Toxicity, Fatty acid metabolism, gamma-Hexachlorocyclohexane degradation, Tryptophan metabolism
0.6229802
0.953
292
drug_resistance_and_metabolism_h
BioCarta
H003538_01
Info
Actin, beta
H003538_01
NM_001101
288061
ACTB
Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes
0.6253266
0.956
293
drug_resistance_and_metabolism_h
BioCarta
H013267_01
Info
Homo sapiens clone R2 ErbB-3 R2 (c-erbB-3) mRNA, partial cds
H013267_01
U88358
306251

Neuroregulin receptor degredation protein-1 Controls ErbB3 receptor recycling, Role of ERBB2 in Signal Transduction and Oncology, cell_cycle, cell_signaling, signal_transduction, tsonc
0.6380266
1.054
294
drug_resistance_and_metabolism_h
BioCarta
H001853_01
Info
Cellular retinoic acid-binding protein 1
H001853_01
S74445
7678
CRABP1
Perou's- Intrinsic- Breast-Cancer-Genes
0.6817674
0.954
295
drug_resistance_and_metabolism_h
BioCarta
H002094_01
Info
Thymidylate synthetase
H002094_01
X02308
82962
TYMS
One carbon pool by folate, Pyrimidine metabolism, metabolism, pharmacology
0.6945693
1.041
296
drug_resistance_and_metabolism_h
BioCarta
H002029_01
Info
V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
H002029_01
M34309
199067
ERBB3
Neuroregulin receptor degredation protein-1 Controls ErbB3 receptor recycling, Role of ERBB2 in Signal Transduction and Oncology, cell_cycle, cell_signaling, signal_transduction, tsonc
0.7019431
1.035
297
drug_resistance_and_metabolism_h
BioCarta
H003542_01
Info
V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene
H003542_01
M11730
323910
ERBB2
Perou's- Intrinsic- Breast-Cancer-Genes, Role of ERBB2 in Signal Transduction and Oncology, Trefoil Factors Initiate Mucosal Healing, immunology, signal_transduction, tsonc
0.7160857
1.031
298
drug_resistance_and_metabolism_h
BioCarta
H003482_01
Info
Catechol-O-methyltransferase
H003482_01
NM_000754
240013
COMT
Tyrosine metabolism, behavior, immunology
0.777803
1.026
299
drug_resistance_and_metabolism_h
BioCarta
H006841_01
Info
Homo sapiens mRNA; cDNA DKFZp564P073 (from clone DKFZp564P073)
H006841_01
AL049301
278577

Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology
0.7810094
0.98
300
drug_resistance_and_metabolism_h
BioCarta
H000245_01
Info
Peroxisome proliferative activated receptor, gamma
H000245_01
L40904
100724
PPARG
Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Nuclear Receptors in Lipid Metabolism and Toxicity, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, Visceral Fat Deposits and the Metabolic Syndrome
0.7837641
0.944
301
drug_resistance_and_metabolism_h
BioCarta
H003772_01
Info
Xeroderma pigmentosum, complementation group C
H003772_01
D21089
320
XPC
DNA_damage, immunology
0.7950726
0.977
302
drug_resistance_and_metabolism_h
BioCarta
H003355_01
Info
Retinoid X receptor, gamma
H003355_01
U38480
26550
RXRG
development
0.8348881
1.017
303
drug_resistance_and_metabolism_h
BioCarta
H001977_01
Info
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
H001977_01
AF085692
90786
ABCC3
Multi-Drug Resistance Factors, Nuclear Receptors in Lipid Metabolism and Toxicity
0.8363263
1.021
304
drug_resistance_and_metabolism_h
BioCarta
H002350_01
Info
Peroxisome proliferative activated receptor, alpha
H002350_01
L02932
998
PPARA
Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Nuclear Receptors in Lipid Metabolism and Toxicity, Regulation of PGC-1a, ▀-arrestins in GPCR Desensitization, Toll-Like Receptor Pathway
0.8655149
1.015
305
drug_resistance_and_metabolism_h
BioCarta
H003711_01
Info
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)
H003711_01
M58603
83428
NFKB1
Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAPKinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a ...
0.8665095
1.017
306
drug_resistance_and_metabolism_h
BioCarta
H002373_01
Info
MutS (E. coli) homolog 3
H002373_01
U61981
42674
MSH3
DNA_damage, immunology
0.8910817
0.986
307
drug_resistance_and_metabolism_h
BioCarta
H015889_01
Info
BCL2-like 1
H015889_01
NM_001191
305890
BCL2L1
Apoptotic Signaling in Response to DNA Damage, IL-2 Receptor Beta Chain in T cell Activation, Opposing roles of AIF in Apoptosis and Cell Survival, Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, immunology
0.996743
1.001
308
pmlPathway_h
BioCarta
H002420_01
Info
Promyelocytic leukemia
H002420_01
M79462
89633
PML
Regulation of transcriptional activity by PML, gene_regulation, immunology, transcription
0.0004143
0.71
309
pmlPathway_h
BioCarta
H003112_01
Info
Retinoblastoma 1 (including osteosarcoma)
H003112_01
L41870
75770
RB1
BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc
0.0008596
0.674
310
pmlPathway_h
BioCarta
H000570_01
Info
CREB binding protein (Rubinstein-Taybi syndrome)
H000570_01
U47741
23598
CREBBP
gene_regulation, transcription
0.0048718
1.469
311
pmlPathway_h
BioCarta
H002789_01
Info
Tumor protein p53 (Li-Fraumeni syndrome)
H002789_01
NM_000546
1846
TP53
Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc
0.0273242
1.207
312
pmlPathway_h
BioCarta
H002049_01
Info
Death-associated protein 6
H002049_01
AB015051
180224
DAXX
FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , Regulation of transcriptional activity by PML, Stress Induction of HSP Regulation, apoptosis
0.0788021
1.159
313
pmlPathway_h
BioCarta
H002506_01
Info
Tumor necrosis factor receptor superfamily, member 1B
H002506_01
M32315
256278
TNFRSF1B
TNFR2 Signaling Pathway, immunology
0.1166754
1.17
314
pmlPathway_h
BioCarta
H007835_01
Info
Sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 1
H007835_01
NM_012238
31176
SIRT1
Regulation of transcriptional activity by PML
0.2402857
0.874
315
pmlPathway_h
BioCarta
H003644_01
Info
Tumor necrosis factor receptor superfamily, member 6
H003644_01
X63717
82359
TNFRSF6
apoptosis, immunology
0.4621499
0.927
316
pmlPathway_h
BioCarta
H002907_01
Info
Retinoic acid receptor, alpha
H002907_01
X06614
250505
RARA
Degradation of the RAR and RXR by the proteasome, Map Kinase Inactivation of SMRT Corepressor, Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, Nuclear Receptors in Lipid Metabolism and Toxicity, Regulation of transcriptional activity by PML, Transcription Regulation by Methyltransferase of CARM1, development
0.4825926
1.084
317
pmlPathway_h
BioCarta
H000554_01
Info
Nuclear antigen Sp100
H000554_01
AF056322
77617
SP100
Regulation of transcriptional activity by PML, gene_regulation, transcription
0.8369981
0.979
318
EGF_receptor_signaling_pathway_h
BioCarta
H002040_01
Info
Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)
H002040_01
X00588
77432
EGFR
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degredation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc
0.0004362
0.669
319
EGF_receptor_signaling_pathway_h
BioCarta
H002055_01
Info
Growth factor receptor-bound protein 2
H002055_01
M96995
296381
GRB2
Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...
0.0022348
1.459
320
EGF_receptor_signaling_pathway_h
BioCarta
H011186_01
Info
Growth factor receptor-bound protein 7
H011186_01
D43772
86859
GRB7
Perou's- Intrinsic- Breast-Cancer-Genes
0.0262471
0.742
321
EGF_receptor_signaling_pathway_h
BioCarta
H000928_01
Info
Epiregulin
H000928_01
D30783
115263
EREG

0.1139333
0.813
322
EGF_receptor_signaling_pathway_h
BioCarta
H010696_01
Info
NCK adaptor protein 2
H010696_01
AF047487
101695
NCK2

0.1245534
1.19
323
EGF_receptor_signaling_pathway_h
BioCarta
H006546_01
Info
Neuronal Shc
H006546_01
D84361
151123
SHC3

0.1304854
1.158
324
EGF_receptor_signaling_pathway_h
BioCarta
H002156_01
Info
Epidermal growth factor receptor pathway substrate 15
H002156_01
Z29064
79095
EPS15
Endocytotic role of NDK, Phosphins and Dynamin, immunology, misc
0.1357021
0.865
325
EGF_receptor_signaling_pathway_h
BioCarta
H002376_01
Info
Epidermal growth factor receptor pathway substrate 8
H002376_01
U12535
2132
EPS8
misc
0.231316
0.841
326
EGF_receptor_signaling_pathway_h
BioCarta
H002632_01
Info
GRB2-associated binding protein 1
H002632_01
U43885
239706
GAB1
Signaling of Hepatocyte Growth Factor Receptor
0.3021702
1.095
327
GPCRs_Class_A_Rhodopsin-like_h
GO
H002088_01
Info
Prostaglandin E receptor 4 (subtype EP4)
H002088_01
L25124
199248
PTGER4
Eicosanoid Metabolism
0.0029063
0.734
328
GPCRs_Class_A_Rhodopsin-like_h
GO
H004080_01
Info
Histamine receptor H3
H004080_01
NM_007232
251399
HRH3

0.0035969
0.66
329
GPCRs_Class_A_Rhodopsin-like_h
GO
H003668_01
Info
Histamine receptor H1
H003668_01
Z34897
1570
HRH1

0.0076811
0.709
330
GPCRs_Class_A_Rhodopsin-like_h
GO
H002813_01
Info
5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
H002813_01
U68488
73739
HTR7
immunology
0.0089719
1.292
331
GPCRs_Class_A_Rhodopsin-like_h
GO
H002667_01
Info
Prostaglandin E receptor 1 (subtype EP1), 42kD
H002667_01
L22647
159360
PTGER1
Eicosanoid Metabolism, Phospholipase C-epsilon pathway
0.0102067
1.228
332
GPCRs_Class_A_Rhodopsin-like_h
GO
H003590_01
Info
Retinal G protein coupled receptor
H003590_01
U14910
1544
RGR

0.0153777
1.301
333
GPCRs_Class_A_Rhodopsin-like_h
GO
H002494_01
Info
Adrenergic, alpha-1B-, receptor
H002494_01
U03865
123055
ADRA1B
Phospholipase C d1 in phospholipid associated cell signaling
0.0200341
1.572
334
GPCRs_Class_A_Rhodopsin-like_h
GO
H002167_01
Info
Chemokine binding protein 2
H002167_01
U94888
117572
CCBP2

0.0225142
0.731
335
GPCRs_Class_A_Rhodopsin-like_h
GO
H002027_01
Info
Prostaglandin I2 (prostacyclin) receptor (IP)
H002027_01
D25418
393
PTGIR
Eicosanoid Metabolism, immunology
0.0236242
0.789
336
GPCRs_Class_A_Rhodopsin-like_h
GO
H003343_01
Info
Galanin receptor 1
H003343_01
NM_001480
272191
GALR1

0.0260438
0.759
337
GPCRs_Class_A_Rhodopsin-like_h
GO
H002347_01
Info
Leukotriene b4 receptor (chemokine receptor-like 1)
H002347_01
D89078
28408
LTB4R
immunology
0.0284508
1.35
338
GPCRs_Class_A_Rhodopsin-like_h
GO
H003130_01
Info
Interleukin 8 receptor, beta
H003130_01
L19593
846
IL8RB
immunology
0.0345675
1.307
339
GPCRs_Class_A_Rhodopsin-like_h
GO
H002464_01
Info
G protein-coupled receptor 2
H002464_01
AF215981
278446
GPR2
immunology
0.0493902
0.772
340
GPCRs_Class_A_Rhodopsin-like_h
GO
H006487_01
Info
Neuropeptide Y receptor Y6 (pseudogene)
H006487_01
D86519
73086
NPY6R

0.0535714
1.212
341
GPCRs_Class_A_Rhodopsin-like_h
GO
H003428_01
Info
5-hydroxytryptamine (serotonin) receptor 2A
H003428_01
X57830
298623
HTR2A
immunology
0.0558704
1.169
342
GPCRs_Class_A_Rhodopsin-like_h
GO
H002592_01
Info
Opioid receptor, mu 1
H002592_01
L25119
2353
OPRM1
behavior, immunology
0.0609704
0.812
343
GPCRs_Class_A_Rhodopsin-like_h
GO
H003745_01
Info
Neuropeptide Y receptor Y1
H003745_01
NM_000909
169266
NPY1R
Perou's- Intrinsic- Breast-Cancer-Genes, immunology
0.0754043
1.285
344
GPCRs_Class_A_Rhodopsin-like_h
GO
H002332_01
Info
Bradykinin receptor B2
H002332_01
NM_000623
250882
BDKRB2
Actions of Nitric Oxide in the Heart, angiogenesis, immunology
0.0806551
0.852
345
GPCRs_Class_A_Rhodopsin-like_h
GO
H003670_01
Info
Adrenergic, beta-1-, receptor
H003670_01
J03019
99913
ADRB1
behavior, immunology
0.0878218
1.205
346
GPCRs_Class_A_Rhodopsin-like_h
GO
H002366_01
Info
Chemokine (C-C motif) receptor 9
H002366_01
NM_006641
225946
CCR9

0.0908646
1.196
347
GPCRs_Class_A_Rhodopsin-like_h
GO
H002585_01
Info
G protein-coupled receptor 17
H002585_01
Z94155
46453
GPR17

0.1077387
1.234
348
GPCRs_Class_A_Rhodopsin-like_h
GO
H002758_01
Info
Chemokine-like receptor 1
H002758_01
U79526
159553
CMKLR1
immunology
0.1103372
1.187
349
GPCRs_Class_A_Rhodopsin-like_h
GO
H003899_01
Info
Chemokine (C-C motif) receptor 1
H003899_01
D10925
301921
CCR1
Selective expression of chemokine receptors during T-cell polarization, immunology
0.1258208
1.15
350
GPCRs_Class_A_Rhodopsin-like_h
GO
H002321_01
Info
G protein-coupled receptor 30
H002321_01
AF015257
113207
GPR30
immunology
0.1344665
1.164
351
GPCRs_Class_A_Rhodopsin-like_h
GO
H015702_01
Info
G protein-coupled receptor 44
H015702_01
NM_004778
299567
GPR44

0.1450231
1.171
352
GPCRs_Class_A_Rhodopsin-like_h
GO
H002567_01
Info
Thyroid stimulating hormone receptor
H002567_01
M31774
123078
TSHR
immunology
0.1458901
0.876
353
GPCRs_Class_A_Rhodopsin-like_h
GO
H002097_01
Info
Dopamine receptor D2
H002097_01
X51362
73893
DRD2
behavior, immunology
0.1531006
0.865
354
GPCRs_Class_A_Rhodopsin-like_h
GO
H002110_01
Info
Coagulation factor II (thrombin) receptor
H002110_01
NM_001992
128087
F2R
Perou's- Intrinsic- Breast-Cancer-Genes, Acute Myocardial Infarction, Extrinsic Prothrombin Activation Pathway, Fibrinolysis Pathway, Intrinsic Prothrombin Activation Pathway, immunology
0.1560498
0.883
355
GPCRs_Class_A_Rhodopsin-like_h
GO
H002476_01
Info
Chemokine (C-C motif) receptor 5
H002476_01
NM_000579
54443
CCR5
HIV Induced T Cell Apoptosis, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, NO2-dependent IL 12 Pathway in NK cells, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Selective expression of chemokine receptors during T-cell polarization, immunology
0.1574808
0.842
356
GPCRs_Class_A_Rhodopsin-like_h
GO
H015524_01
Info
AD026 protein
H015524_01
NM_020683
28847
AD026

0.1577677
1.184
357
GPCRs_Class_A_Rhodopsin-like_h
GO
H002454_01
Info
Follicle stimulating hormone receptor
H002454_01
M65085
1428
FSHR
Regulation of Spermatogenesis by CREM
0.1580303
1.111
358
GPCRs_Class_A_Rhodopsin-like_h
GO
H002487_01
Info
Complement component 5 receptor 1 (C5a ligand)
H002487_01
M62505
2161
C5R1
immunology
0.1622511
1.213
359
GPCRs_Class_A_Rhodopsin-like_h
GO
H000667_01
Info
Purinergic receptor (family A group 5)
H000667_01
AF000546
189999
P2Y5

0.1930389
0.884
360
GPCRs_Class_A_Rhodopsin-like_h
GO
H009013_01
Info
Dopamine receptor D2
H009013_01
AF176812
73893
DRD2
behavior, immunology
0.2238033
1.119
361
GPCRs_Class_A_Rhodopsin-like_h
GO
H003535_01
Info
Galanin receptor 3
H003535_01
AF073799
158353
GALR3

0.227577
1.12
362
GPCRs_Class_A_Rhodopsin-like_h
GO
H003381_01
Info
Melatonin receptor 1A
H003381_01
U14108
248147
MTNR1A

0.3138134
1.113
363
GPCRs_Class_A_Rhodopsin-like_h
GO
H015755_01
Info
Chemokine (C-C motif) receptor 1
H015755_01
NM_001295
301921
CCR1
Selective expression of chemokine receptors during T-cell polarization, immunology
0.3366567
1.129
364
GPCRs_Class_A_Rhodopsin-like_h
GO
H006918_01
Info
Neuropeptide G protein-coupled receptor; neuropeptide FF 2
H006918_01
NM_004885
99231
NPGPR

0.4203767
0.905
365
GPCRs_Class_A_Rhodopsin-like_h
GO
H002976_01
Info
G protein-coupled receptor 9
H002976_01
X95876
198252
GPR9
IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, mCalpain and friends in Cell motility, NO2-dependent IL 12 Pathway in NK cells, Selective expression of chemokine receptors during T-cell polarization
0.4390046
0.918
366
GPCRs_Class_A_Rhodopsin-like_h
GO
H002698_01
Info
Adrenergic, beta-3-, receptor
H002698_01
NM_000025
2549
ADRB3
behavior, immunology
0.4399337
0.93
367
GPCRs_Class_A_Rhodopsin-like_h
GO
H010325_01
Info
Chemokine (C-C motif) receptor-like 2
H010325_01
AF015525
302043
CCRL2

0.4610352
0.915
368
GPCRs_Class_A_Rhodopsin-like_h
GO
H002378_01
Info
Adrenergic, alpha-2C-, receptor
H002378_01
J03853
123022
ADRA2C
behavior, immunology
0.4753686
1.073
369
GPCRs_Class_A_Rhodopsin-like_h
GO
H003577_01
Info
Adrenergic, alpha-1A-, receptor
H003577_01
D32202
52931
ADRA1A
behavior
0.5296756
1.062
370
GPCRs_Class_A_Rhodopsin-like_h
GO
H003424_01
Info
Chemokine (C-C motif) receptor 3
H003424_01
U28694
158324
CCR3
CCR3 signaling in Eosinophils, IL 5 Signaling Pathway, Selective expression of chemokine receptors during T-cell polarization, The Role of Eosinophils in the Chemokine Network of Allergy, immunology
0.5671442
1.138
371
GPCRs_Class_A_Rhodopsin-like_h
GO
H007948_01
Info
F-box and WD-40 domain protein 2
H007948_01
NM_012164
13755
FBXW2

0.5814024
1.048
372
GPCRs_Class_A_Rhodopsin-like_h
GO
H003584_01
Info
Platelet-activating factor receptor
H003584_01
D10202
46
PTAFR
angiogenesis, immunology
0.5977382
1.05
373
GPCRs_Class_A_Rhodopsin-like_h
GO
H003654_01
Info
Coagulation factor II (thrombin) receptor-like 2
H003654_01
U92971
194351
F2RL2
immunology
0.6746058
0.966
374
GPCRs_Class_A_Rhodopsin-like_h
GO
H002380_01
Info
Chemokine (C-C motif) receptor 8
H002380_01
D49919
113222
CCR8
immunology
0.6915296
1.035
375
GPCRs_Class_A_Rhodopsin-like_h
GO
H002317_01
Info
Chemokine (C-X3-C) receptor 1
H002317_01
U20350
78913
CX3CR1
immunology
0.7275779
1.038
376
GPCRs_Class_A_Rhodopsin-like_h
GO
H016261_01
Info
Putative G protein-coupled receptor 92
H016261_01
NM_020400
330563
GPR92

0.7713793
0.962
377
GPCRs_Class_A_Rhodopsin-like_h
GO
H012371_01
Info
Thyroid stimulating hormone receptor
H012371_01
S82807
123078
TSHR
immunology
0.7783963
1.03
378
GPCRs_Class_A_Rhodopsin-like_h
GO
H003426_01
Info
Prostaglandin D2 receptor (DP)
H003426_01
U31099
158326
PTGDR

0.800069
0.971
379
GPCRs_Class_A_Rhodopsin-like_h
GO
H003721_01
Info
Dopamine receptor D4
H003721_01
L12398
99922
DRD4
behavior, immunology
0.8251335
1.023
380
GPCRs_Class_A_Rhodopsin-like_h
GO
H002672_01
Info
G protein-coupled receptor
H002672_01
U67784
23016
RDC1

0.8527585
0.967
381
GPCRs_Class_A_Rhodopsin-like_h
GO
H003854_01
Info
Burkitt lymphoma receptor 1, GTP-binding protein
H003854_01
X68149
113916
BLR1

0.882872
0.982
382
GPCRs_Class_A_Rhodopsin-like_h
GO
H002271_01
Info
Neuropeptide Y receptor Y2
H002271_01
NM_000910
37125
NPY2R

0.9438408
0.993
383
GPCRs_Class_A_Rhodopsin-like_h
GO
H002797_01
Info
Adenosine A3 receptor
H002797_01
NM_000677
258
ADORA3

0.9481775
0.993
384
GPCRs_Class_A_Rhodopsin-like_h
GO
H002327_01
Info
Adenosine A1 receptor
H002327_01
L22214
77867
ADORA1
immunology
0.9613941
1.005



Table - Significant pathway by running the Hotelling T-square test consist of the following genes (sorted by p-values).


Broad PathwayPathway descriptionUnique idAnno-
tations
DescriptionCloneGB accUG clusterGene symbolDefined genelistsParametric p-valueGeometric mean of ratios
(class Disesase /class Normal )
1
spryPathway_h
BioCarta
H002040_01
Info
Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)
H002040_01
X00588
77432
EGFR
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degredation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc
0.0004362
0.669
2
spryPathway_h
BioCarta
H002055_01
Info
Growth factor receptor-bound protein 2
H002055_01
M96995
296381
GRB2
Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...
0.0022348
1.459
3
spryPathway_h
BioCarta
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
4
spryPathway_h
BioCarta
H002847_01
Info
Protein tyrosine phosphatase, receptor type, B
H002847_01
X54131
123641
PTPRB
Sprouty regulation of tyrosine kinase signals, cell_cycle, cell_signaling
0.0110757
1.299
5
spryPathway_h
BioCarta
H003178_01
Info
Mitogen-activated protein kinase 3
H003178_01
X60188
861
MAPK3
Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...
0.0986041
1.184
6
spryPathway_h
BioCarta
H001600_01
Info
RAS p21 protein activator (GTPase activating protein) 1
H001600_01
M23379
758
RASA1
EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction
0.1015906
0.844
7
spryPathway_h
BioCarta
H002722_01
Info
Mitogen-activated protein kinase kinase 1
H002722_01
L11284
3446
MAP2K1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...
0.7377933
0.973
8
ST_p38_MAPK_Pathway_h
Signalling Transduction KE
H003352_01
Info
Interleukin 1 receptor, type I
H003352_01
M27492
82112
IL1R1
NF-kB Signaling Pathway, Signal transduction through IL1R, immunology
0.000502
0.677
9
ST_p38_MAPK_Pathway_h
Signalling Transduction KE
H003200_01
Info
Mitogen-activated protein kinase kinase 3
H003200_01
D87116
180533
MAP2K3
fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway
0.0009666
1.561
10
ST_p38_MAPK_Pathway_h
Signalling Transduction KE
H002186_01
Info
Serum response factor (c-fos serum response element-binding transcription factor)
H002186_01
J03161
155321
SRF
EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription
0.0017465
0.722
11
ST_p38_MAPK_Pathway_h
Signalling Transduction KE
H000309_01
Info
CAMP response element-binding protein CRE-BPa
H000309_01
L05515
149
H_GS165L15.1

0.0078273
1.479
12
ST_p38_MAPK_Pathway_h
Signalling Transduction KE
H002895_01
Info
Mitogen-activated protein kinase 14
H002895_01
L35263
79107
MAPK14
BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAPKinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm ...
0.0086925
1.429
13
ST_p38_MAPK_Pathway_h
Signalling Transduction KE
H003611_01
Info
Mitogen-activated protein kinase kinase 4
H003611_01
L36870
75217
MAP2K4
Perou's- Intrinsic- Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system
0.012502
0.753
14
ST_p38_MAPK_Pathway_h
Signalling Transduction KE
H003008_01
Info
Mitogen-activated protein kinase kinase kinase 4
H003008_01
AF002715
32353
MAP3K4
MAPKinase Signaling Pathway, Phosphatidylinositol signaling system
0.0127738
0.707
15
ST_p38_MAPK_Pathway_h
Signalling Transduction KE
H004258_01
Info
Elongation factor-2 kinase
H004258_01
U93850
259855
HSU93850
Eukaryotic protein translation
0.0132437
0.748
16
ST_p38_MAPK_Pathway_h
Signalling Transduction KE
H011228_01
Info
G protein-coupled receptor kinase 7
H011228_01
AL137615
261828
GPRK7
Perou's- Intrinsic- Breast-Cancer-Genes, Erk1/Erk2 Mapk Signaling pathway, MAPKinase Signaling Pathway, Phosphatidylinositol signaling system
0.0572981
1.27
17
ST_p38_MAPK_Pathway_h
Signalling Transduction KE
H003107_01
Info
Mitogen-activated protein kinase 13
H003107_01
AF004709
178695
MAPK13
Keratinocyte Differentiation, MAPKinase Signaling Pathway, Stathmin and breast cancer resistance to antimicrotubule agents, Phosphatidylinositol signaling system
0.0717244
1.171
18
ST_p38_MAPK_Pathway_h
Signalling Transduction KE
H008351_01
Info
Dual specificity phosphatase 10
H008351_01
AB026436
177534
DUSP10

0.382916
0.922
19
ST_p38_MAPK_Pathway_h
Signalling Transduction KE
H006851_01
Info
TAK1-binding protein 2; KIAA0733 protein
H006851_01
AL117407
109727
KIAA0733
Toll-Like Receptor Pathway
0.4908732
1.066
20
ST_p38_MAPK_Pathway_h
Signalling Transduction KE
H002340_01
Info
Mitogen-activated protein kinase kinase kinase 5
H002340_01
U67156
151988
MAP3K5
HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , The 4-1BB-dependent immune response
0.5393151
1.07
21
ST_p38_MAPK_Pathway_h
Signalling Transduction KE
H002173_01
Info
Cell division cycle 42 (GTP-binding protein, 25kD)
H002173_01
AL121735
146409
CDC42
Agrin in Postsynaptic Differentiation, How does salmonella hijack a cell, p38 MAPK Signaling Pathway , Ras Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, cell_cycle, cell_signaling, signal_transduction
0.6486191
1.035
22
ST_p38_MAPK_Pathway_h
Signalling Transduction KE
H003612_01
Info
V-akt murine thymoma viral oncogene homolog 1
H003612_01
M63167
71816
AKT1
Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signalling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation ...
0.6741257
1.038
23
ST_p38_MAPK_Pathway_h
Signalling Transduction KE
H001386_01
Info
Mitogen-activated protein kinase kinase kinase 10
H001386_01
X90846
30223
MAP3K10
MAPKinase Signaling Pathway, Phosphatidylinositol signaling system
0.7007387
0.968
24
ST_p38_MAPK_Pathway_h
Signalling Transduction KE
H003434_01
Info
Dual specificity phosphatase 1
H003434_01
NM_004417
171695
DUSP1
CD40L Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, TNFR2 Signaling Pathway
0.8183145
0.968
25
ST_p38_MAPK_Pathway_h
Signalling Transduction KE
H003711_01
Info
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)
H003711_01
M58603
83428
NFKB1
Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAPKinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a ...
0.8665095
1.017
26
ST_p38_MAPK_Pathway_h
Signalling Transduction KE
H003163_01
Info
CAMP responsive element binding protein 1
H003163_01
M27691
79194
CREB1
Ca++/ Calmodulin-dependent Protein Kinase Activation, Calcium Signaling by HBx of Hepatitis B virus, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia-Inducible Factor in the Cardiovascular System, Inhibition of Huntington\'s disease neurodegeneration by histone deacetylase inhibitors, MAPKinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Repression of Pain Sensation by the Transcriptional Regulator DREAM, Role of Erk5 in Neuronal Survival, Signaling Pathway from G-Protein Families, Transcription factor CREB and its extracellular signals, Transcription Regulation by Methyltransferase of CARM1, immunology
0.9300928
1.009
27
ST_p38_MAPK_Pathway_h
Signalling Transduction KE
H012856_01
Info
MAP kinase-interacting serine/threonine kinase 1
H012856_01
AB000409
5591
MKNK1
Erk1/Erk2 Mapk Signaling pathway, MAPKinase Signaling Pathway, mTOR Signaling Pathway, p38 MAPK Signaling Pathway , Regulation of eIF4e and p70 S6 Kinase, Phosphatidylinositol signaling system
0.9455231
0.992
28
EMT_UP_h
Jechlinger_et_al_2003
H003225_01
Info
Interferon regulatory factor 7
H003225_01
AF076494
166120
IRF7
gene_regulation, transcription
6.44e-05
1.728
29
EMT_UP_h
Jechlinger_et_al_2003
H000825_01
Info
S100 calcium-binding protein A8 (calgranulin A)
H000825_01
X06234
100000
S100A8
immunology
0.0001788
2.746
30
EMT_UP_h
Jechlinger_et_al_2003
H001850_01
Info
Interferon-stimulated protein, 15 kDa
H001850_01
M13755
833
ISG15

0.0003862
1.943
31
EMT_UP_h
Jechlinger_et_al_2003
H000473_01
Info
Uridine phosphorylase
H000473_01
X90858
77573
UP
Pyrimidine metabolism
0.0005102
1.339
32
EMT_UP_h
Jechlinger_et_al_2003
H002726_01
Info
B-cell CLL/lymphoma 3
H002726_01
M31732
31210
BCL3
tsonc
0.0147426
1.351
33
EMT_UP_h
Jechlinger_et_al_2003
H003466_01
Info
CD68 antigen
H003466_01
S57235
246381
CD68
angiogenesis, immunology, metastasis
0.0179458
1.335
34
EMT_UP_h
Jechlinger_et_al_2003
H003299_01
Info
Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
H003299_01
M59979
88474
PTGS1
Aspirin Blocks Signaling Pathway Involved in Platelet Activation, Eicosanoid Metabolism, Mechanism of Acetaminophen Activity and Toxicity, Prostaglandin and leukotriene metabolism, immunology
0.023304
0.813
35
EMT_UP_h
Jechlinger_et_al_2003
H003029_01
Info
Disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein)
H003029_01
U53446
81988
DAB2

0.0291633
0.78
36
EMT_UP_h
Jechlinger_et_al_2003
H003752_01
Info
Platelet-derived growth factor receptor, beta polypeptide
H003752_01
J03278
76144
PDGFRB
cell_cycle, cell_signaling, immunology, misc, signal_transduction
0.0333891
0.832
37
EMT_UP_h
Jechlinger_et_al_2003
H006885_01
Info
Ribonuclease 6 precursor
H006885_01
NM_003730
8297
RNASE6PL

0.0955467
1.208
38
EMT_UP_h
Jechlinger_et_al_2003
H000998_01
Info
Solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
H000998_01
AB018010
79748
SLC3A2
Perou's- Intrinsic- Breast-Cancer-Genes
0.1156436
0.843
39
EMT_UP_h
Jechlinger_et_al_2003
H001908_01
Info
Discoidin domain receptor family, member 2
H001908_01
X74764
71891
DDR2

0.1167676
0.839
40
EMT_UP_h
Jechlinger_et_al_2003
H001001_01
Info
Procollagen C-endopeptidase enhancer
H001001_01
NM_002593
202097
PCOLCE

0.1228497
0.868
41
EMT_UP_h
Jechlinger_et_al_2003
H000774_01
Info
Collagen, type VI, alpha 1
H000774_01
X15880
108885
COL6A1

0.1448402
0.841
42
EMT_UP_h
Jechlinger_et_al_2003
H002775_01
Info
Platelet-derived growth factor receptor, alpha polypeptide
H002775_01
M21574
74615
PDGFRA
Perou's- Intrinsic- Breast-Cancer-Genes, CBL mediated ligand-induced downregulation of EGF receptors, Erk1/Erk2 Mapk Signaling pathway, PDGF Signaling Pathway, Phospholipids as signalling intermediaries, Rac 1 cell motility signaling pathway, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, immunology, signal_transduction
0.1636921
1.107
43
EMT_UP_h
Jechlinger_et_al_2003
H010646_01
Info
Ribonuclease 6 precursor
H010646_01
AK001769
8297
RNASE6PL

0.1872503
1.127
44
EMT_UP_h
Jechlinger_et_al_2003
H002295_01
Info
Adenosine deaminase
H002295_01
X02994
1217
ADA
Purine metabolism, gene_regulation, immunology, transcription
0.1882263
0.871
45
EMT_UP_h
Jechlinger_et_al_2003
H012626_01
Info
Beta-2-microglobulin
H012626_01
AB021288
75415
B2M
Antigen Processing and Presentation, CTL mediated immune response against target cells , Ras-Independent pathway in NK cell-mediated cytotoxicity, immunology
0.1923361
1.156
46
EMT_UP_h
Jechlinger_et_al_2003
H003645_01
Info
Interleukin 11
H003645_01
X58377
1721
IL11
Cytokines and Inflammatory Response, Erythrocyte Differentiation Pathway, Regulation of hematopoiesis by cytokines, immunology
0.2074062
1.116
47
EMT_UP_h
Jechlinger_et_al_2003
H003593_01
Info
Collagen, type VI, alpha 2
H003593_01
AL096746
159263
COL6A2

0.300891
1.098
48
EMT_UP_h
Jechlinger_et_al_2003
H001198_01
Info
Homo sapiens, alpha-1 (VI) collagen
H001198_01
M20776
25459


0.3632512
1.1
49
EMT_UP_h
Jechlinger_et_al_2003
H002451_01
Info
Flavin containing monooxygenase 1
H002451_01
M64082
1424
FMO1
immunology, misc
0.3681883
0.911
50
EMT_UP_h
Jechlinger_et_al_2003
H000592_01
Info
Interferon-induced protein with tetratricopeptide repeats 1
H000592_01
X03557
20315
IFIT1

0.4335751
1.121
51
EMT_UP_h
Jechlinger_et_al_2003
H002713_01
Info
Phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
H002713_01
U24577
93304
PLA2G7
Glycerophospholipid metabolism
0.4631812
0.89
52
EMT_UP_h
Jechlinger_et_al_2003
H010497_01
Info
Interferon induced transmembrane protein 3 (1-8U)
H010497_01
X57352
182241
IFITM3

0.5875785
1.062
53
EMT_UP_h
Jechlinger_et_al_2003
H003695_01
Info
Secreted protein, acidic, cysteine-rich (osteonectin)
H003695_01
J03040
111779
SPARC
misc
0.6414286
1.051
54
EMT_UP_h
Jechlinger_et_al_2003
H002330_01
Info
Cadherin 15, M-cadherin (myotubule)
H002330_01
D83542
148090
CDH15

0.7996949
0.974
55
EMT_UP_h
Jechlinger_et_al_2003
H002397_01
Info
Methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
H002397_01
X16396
154672
MTHFD2
Glyoxylate and dicarboxylate metabolism, One carbon pool by folate
0.8081788
0.975
56
EMT_UP_h
Jechlinger_et_al_2003
H002672_01
Info
G protein-coupled receptor
H002672_01
U67784
23016
RDC1

0.8527585
0.967
57
EMT_UP_h
Jechlinger_et_al_2003
H002490_01
Info
Hexabrachion (tenascin C, cytotactin)
H002490_01
X78565
289114
HXB
Perou's- Intrinsic- Breast-Cancer-Genes
0.856155
0.983
58
EMT_UP_h
Jechlinger_et_al_2003
H002283_01
Info
Secretory leukocyte protease inhibitor (antileukoproteinase)
H002283_01
X04470
251754
SLPI
Perou's- Intrinsic- Breast-Cancer-Genes, Proepithelin Conversion to Epithelin and Wound Repair Control, immunology
0.9075348
1.012
59
EMT_UP_h
Jechlinger_et_al_2003
H004245_01
Info
Snail 1 (drosophila homolog), zinc finger protein
H004245_01
AF125377
48029
SNAI1
Downregulated of MTA-3 in ER-negative Breast Tumors
0.9743253
1.003
60
egfPathway_h
The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.
H002040_01
Info
Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)
H002040_01
X00588
77432
EGFR
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degredation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc
0.0004362
0.669
61
egfPathway_h
The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.
H002186_01
Info
Serum response factor (c-fos serum response element-binding transcription factor)
H002186_01
J03161
155321
SRF
EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription
0.0017465
0.722
62
egfPathway_h
The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.
H002055_01
Info
Growth factor receptor-bound protein 2
H002055_01
M96995
296381
GRB2
Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...
0.0022348
1.459
63
egfPathway_h
The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
64
egfPathway_h
The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.
H003611_01
Info
Mitogen-activated protein kinase kinase 4
H003611_01
L36870
75217
MAP2K4
Perou's- Intrinsic- Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system
0.012502
0.753
65
egfPathway_h
The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.
H001365_01
Info
Protein kinase C, beta 1
H001365_01
X07109
77202
PRKCB1
Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbal Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction
0.0304335
1.379
66
egfPathway_h
The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.
H003178_01
Info
Mitogen-activated protein kinase 3
H003178_01
X60188
861
MAPK3
Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...
0.0986041
1.184
67
egfPathway_h
The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.
H001600_01
Info
RAS p21 protein activator (GTPase activating protein) 1
H001600_01
M23379
758
RASA1
EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction
0.1015906
0.844
68
egfPathway_h
The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.
H003158_01
Info
Mitogen-activated protein kinase 8
H003158_01
L26318
190913
MAPK8
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...
0.1287835
1.166
69
egfPathway_h
The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.
H001349_01
Info
Janus kinase 1 (a protein tyrosine kinase)
H001349_01
M64174
50651
JAK1
EGF Signaling Pathway, IFN alpha signaling pathway, IFN gamma signaling pathway , IL 2 signaling pathway, IL 4 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, PDGF Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction
0.2754104
1.129
70
egfPathway_h
The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.
H002722_01
Info
Mitogen-activated protein kinase kinase 1
H002722_01
L11284
3446
MAP2K1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...
0.7377933
0.973
71
insulinPathway_h
BioCarta
H000732_01
Info
Insulin receptor substrate 1
H000732_01
S62539
96063
IRS1
Perou's- Intrinsic- Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology
0.0013348
0.643
72
insulinPathway_h
BioCarta
H002186_01
Info
Serum response factor (c-fos serum response element-binding transcription factor)
H002186_01
J03161
155321
SRF
EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription
0.0017465
0.722
73
insulinPathway_h
BioCarta
H002055_01
Info
Growth factor receptor-bound protein 2
H002055_01
M96995
296381
GRB2
Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...
0.0022348
1.459
74
insulinPathway_h
BioCarta
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
75
insulinPathway_h
BioCarta
H003178_01
Info
Mitogen-activated protein kinase 3
H003178_01
X60188
861
MAPK3
Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...
0.0986041
1.184
76
insulinPathway_h
BioCarta
H001600_01
Info
RAS p21 protein activator (GTPase activating protein) 1
H001600_01
M23379
758
RASA1
EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction
0.1015906
0.844
77
insulinPathway_h
BioCarta
H003158_01
Info
Mitogen-activated protein kinase 8
H003158_01
L26318
190913
MAPK8
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...
0.1287835
1.166
78
insulinPathway_h
BioCarta
H002624_01
Info
Insulin receptor
H002624_01
X02160
89695
INSR
Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Growth Hormone Signaling Pathway, Insulin Signaling Pathway, immunology
0.433218
0.919
79
insulinPathway_h
BioCarta
H002722_01
Info
Mitogen-activated protein kinase kinase 1
H002722_01
L11284
3446
MAP2K1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...
0.7377933
0.973
80
igf1Pathway_h
BioCarta
H000732_01
Info
Insulin receptor substrate 1
H000732_01
S62539
96063
IRS1
Perou's- Intrinsic- Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology
0.0013348
0.643
81
igf1Pathway_h
BioCarta
H002186_01
Info
Serum response factor (c-fos serum response element-binding transcription factor)
H002186_01
J03161
155321
SRF
EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription
0.0017465
0.722
82
igf1Pathway_h
BioCarta
H002055_01
Info
Growth factor receptor-bound protein 2
H002055_01
M96995
296381
GRB2
Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...
0.0022348
1.459
83
igf1Pathway_h
BioCarta
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
84
igf1Pathway_h
BioCarta
H002473_01
Info
Insulin-like growth factor 1 receptor
H002473_01
NM_000875
239176
IGF1R
Perou's- Intrinsic- Breast-Cancer-Genes, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Erk1/Erk2 Mapk Signaling pathway, IGF-1 Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Telomeres, Telomerase, Cellular Aging, and Immortality, The IGF-1 Receptor and Longevity, immunology
0.079692
1.158
85
igf1Pathway_h
BioCarta
H003178_01
Info
Mitogen-activated protein kinase 3
H003178_01
X60188
861
MAPK3
Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...
0.0986041
1.184
86
igf1Pathway_h
BioCarta
H001600_01
Info
RAS p21 protein activator (GTPase activating protein) 1
H001600_01
M23379
758
RASA1
EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction
0.1015906
0.844
87
igf1Pathway_h
BioCarta
H003158_01
Info
Mitogen-activated protein kinase 8
H003158_01
L26318
190913
MAPK8
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...
0.1287835
1.166
88
igf1Pathway_h
BioCarta
H002722_01
Info
Mitogen-activated protein kinase kinase 1
H002722_01
L11284
3446
MAP2K1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...
0.7377933
0.973
89
il6Pathway_h
BioCarta
H002186_01
Info
Serum response factor (c-fos serum response element-binding transcription factor)
H002186_01
J03161
155321
SRF
EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription
0.0017465
0.722
90
il6Pathway_h
BioCarta
H002055_01
Info
Growth factor receptor-bound protein 2
H002055_01
M96995
296381
GRB2
Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...
0.0022348
1.459
91
il6Pathway_h
BioCarta
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
92
il6Pathway_h
BioCarta
H003178_01
Info
Mitogen-activated protein kinase 3
H003178_01
X60188
861
MAPK3
Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...
0.0986041
1.184
93
il6Pathway_h
BioCarta
H001349_01
Info
Janus kinase 1 (a protein tyrosine kinase)
H001349_01
M64174
50651
JAK1
EGF Signaling Pathway, IFN alpha signaling pathway, IFN gamma signaling pathway , IL 2 signaling pathway, IL 4 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, PDGF Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction
0.2754104
1.129
94
il6Pathway_h
BioCarta
H002824_01
Info
Janus kinase 3 (a protein tyrosine kinase, leukocyte)
H002824_01
U09607
99877
JAK3
IL 2 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, IL22 Soluble Receptor Signaling Pathway , IL-7 Signal Transduction, Stat3 Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction
0.4735774
1.051
95
il6Pathway_h
BioCarta
H008390_01
Info
Homo sapiens mRNA; cDNA DKFZp564F053 (from clone DKFZp564F053)
H008390_01
AL049265
71968

immunology
0.6157756
1.05
96
il6Pathway_h
BioCarta
H003110_01
Info
Interleukin 6 (interferon, beta 2)
H003110_01
X04430
93913
IL6
Cells and Molecules involved in local acute inflammatory response, Cytokine Network, Cytokines and Inflammatory Response, Erythrocyte Differentiation Pathway, IL 17 Signaling Pathway, IL 5 Signaling Pathway, IL 6 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, Low-density lipoprotein (LDL) pathway during atherogenesis, Regulation of hematopoiesis by cytokines, Role of ERBB2 in Signal Transduction and Oncology, Signal transduction through IL1R, immunology
0.680804
1.036
97
il6Pathway_h
BioCarta
H003456_01
Info
Interleukin 6 receptor
H003456_01
X12830
193400
IL6R
IL 6 signaling pathway, Role of ERBB2 in Signal Transduction and Oncology, immunology
0.7143407
1.03
98
il6Pathway_h
BioCarta
H002722_01
Info
Mitogen-activated protein kinase kinase 1
H002722_01
L11284
3446
MAP2K1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...
0.7377933
0.973
99
GLUCOSE_DOWN_h
Peng_et_al_2002
H003000_01
Info
RAB5A, member RAS oncogene family
H003000_01
M28215
73957
RAB5A
Phosphoinositides and their downstream targets., Rab GTPases Mark Targets In The Endocytotic Machinery, The role of FYVE-finger proteins in vesicle transport, tsonc
0.0003278
0.591
100
GLUCOSE_DOWN_h
Peng_et_al_2002
H003112_01
Info
Retinoblastoma 1 (including osteosarcoma)
H003112_01
L41870
75770
RB1
BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc
0.0008596
0.674
101
GLUCOSE_DOWN_h
Peng_et_al_2002
H001800_01
Info
Proteasome (prosome, macropain) subunit, alpha type, 5
H001800_01
X61970
76913
PSMA5
Proteasome
0.00104
0.69
102
GLUCOSE_DOWN_h
Peng_et_al_2002
H003760_01
Info
DnaJ (Hsp40) homolog, subfamily A, member 1
H003760_01
L08069
94
DNAJA1

0.0016053
0.695
103
GLUCOSE_DOWN_h
Peng_et_al_2002
H007996_01
Info
GABA(A) receptor-associated protein
H007996_01
NM_007278
7719
GABARAP
Gamma-aminobutyric Acid Receptor Life Cycle
0.0021636
1.497
104
GLUCOSE_DOWN_h
Peng_et_al_2002
H001791_01
Info
Ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
H001791_01
X04741
76118
UCHL1

0.002493
0.711
105
GLUCOSE_DOWN_h
Peng_et_al_2002
H002387_01
Info
MutS (E. coli) homolog 2 (colon cancer, nonpolyposis type 1)
H002387_01
NM_000251
78934
MSH2
DNA_damage, tsonc
0.004273
0.694
106
GLUCOSE_DOWN_h
Peng_et_al_2002
H006293_01
Info
ATPase, H+ transporting, lysosomal (vacuolar proton pump) 21kD
H006293_01
D89052
7476
ATP6F
Perou's- Intrinsic- Breast-Cancer-Genes, ATP synthesis, Oxidative phosphorylation
0.0071282
1.372
107
GLUCOSE_DOWN_h
Peng_et_al_2002
H000152_01
Info
Kinesin-like 1
H000152_01
U37426
8878
KNSL1

0.0084868
0.761
108
GLUCOSE_DOWN_h
Peng_et_al_2002
H011911_01
Info
KIAA0594 protein
H011911_01
AB011166
103283
KIAA0594

0.0129673
1.228
109
GLUCOSE_DOWN_h
Peng_et_al_2002
H001903_01
Info
Polymerase (DNA directed), gamma
H001903_01
X98093
80961
POLG
DNA polymerase, Purine metabolism, Pyrimidine metabolism
0.0148856
0.783
110
GLUCOSE_DOWN_h
Peng_et_al_2002
H007126_01
Info
Mouse Mammary Turmor Virus Receptor homolog
H007126_01
AF052151
18686
MTVR

0.0175107
1.245
111
GLUCOSE_DOWN_h
Peng_et_al_2002
H003739_01
Info
Cell division cycle 2, G1 to S and G2 to M
H003739_01
X05360
184572
CDC2
Activation of Src by Protein-tyrosine phosphatase alpha, AKAP95 role in mitosis and chromosome dynamics, cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, How Progesterone Initiates the Oocyte Maturation, Protein Kinase A at the Centrosome, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of Splicing through Sam68, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, Stathmin and breast cancer resistance to antimicrotubule agents, Phosphatidylinositol signaling system, cell_cycle
0.0222229
0.733
112
GLUCOSE_DOWN_h
Peng_et_al_2002
H012105_01
Info
Testis enhanced gene transcript (BAX inhibitor 1)
H012105_01
X75861
74637
TEGT
transcription
0.0238861
1.237
113
GLUCOSE_DOWN_h
Peng_et_al_2002
H001391_01
Info
KIAA1093 protein
H001391_01
AB029016
117333
KIAA1093

0.0266235
1.238
114
GLUCOSE_DOWN_h
Peng_et_al_2002
H007917_01
Info
Translation factor sui1 homolog
H007917_01
NM_005875
21756
GC20

0.0373086
1.222
115
GLUCOSE_DOWN_h
Peng_et_al_2002
H001311_01
Info
ATP/GTP-binding protein
H001311_01
U73524
87465
HEAB

0.0452149
0.788
116
GLUCOSE_DOWN_h
Peng_et_al_2002
H003973_01
Info
EH domain containing 1
H003973_01
NM_006795
155119
EHD1

0.0507649
1.257
117
GLUCOSE_DOWN_h
Peng_et_al_2002
H000449_01
Info
Endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4
H000449_01
AF011466
122575
EDG4

0.0524489
1.347
118
GLUCOSE_DOWN_h
Peng_et_al_2002
H003719_01
Info
Integrin, beta 7
H003719_01
M68892
1741
ITGB7
cell_signaling, immunology, metastasis
0.0529984
0.815
119
GLUCOSE_DOWN_h
Peng_et_al_2002
H001798_01
Info
Ubiquitin specific protease 12
H001798_01
AF022789
42400
USP12

0.0549997
1.187
120
GLUCOSE_DOWN_h
Peng_et_al_2002
H000564_01
Info
Protein kinase C binding protein 1
H000564_01
AB032951
75871
PRKCBP1

0.0986503
0.835
121
GLUCOSE_DOWN_h
Peng_et_al_2002
H002491_01
Info
Bone morphogenetic protein 1
H002491_01
NM_006129
1274
BMP1
development
0.1079128
0.821
122
GLUCOSE_DOWN_h
Peng_et_al_2002
H002928_01
Info
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
H002928_01
X69398
82685
CD47
Perou's- Intrinsic- Breast-Cancer-Genes, angiogenesis, cell_signaling, immunology, metastasis
0.11106
0.854
123
GLUCOSE_DOWN_h
Peng_et_al_2002
H012158_01
Info
Upregulated by 1,25-dihydroxyvitamin D-3
H012158_01
S73591
179526
VDUP1

0.1293789
1.193
124
GLUCOSE_DOWN_h
Peng_et_al_2002
H003050_01
Info
Chaperonin containing TCP1, subunit 4 (delta)
H003050_01
AF026291
79150
CCT4
B Cell Survival Pathway
0.1325252
1.126
125
GLUCOSE_DOWN_h
Peng_et_al_2002
H001622_01
Info
RAB31, member RAS oncogene family
H001622_01
U59877
223025
RAB31
Perou's- Intrinsic- Breast-Cancer-Genes
0.152499
1.183
126
GLUCOSE_DOWN_h
Peng_et_al_2002
H002970_01
Info
Integrin-linked kinase
H002970_01
U40282
6196
ILK
PTEN dependent cell cycle arrest and apoptosis, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction
0.1701136
1.128
127
GLUCOSE_DOWN_h
Peng_et_al_2002
H002365_01
Info
Activated p21cdc42Hs kinase
H002365_01
L13738
153937
ACK1

0.173678
1.162
128
GLUCOSE_DOWN_h
Peng_et_al_2002
H000644_01
Info
Protein phosphatase 2, regulatory subunit B (B56), alpha isoform
H000644_01
L42373
155079
PPP2R5A
cell_cycle, cell_signaling, signal_transduction
0.1872145
0.884
129
GLUCOSE_DOWN_h
Peng_et_al_2002
H009793_01
Info
Rac/Cdc42 guanine exchange factor (GEF) 6
H009793_01
D25304
79307
ARHGEF6
Agrin in Postsynaptic Differentiation
0.2184793
1.139
130
GLUCOSE_DOWN_h
Peng_et_al_2002
H001256_01
Info
Sialyltransferase 4C (beta-galactosidase alpha-2,3-sialytransferase)
H001256_01
X74570
75268
SIAT4C

0.2276302
0.892
131
GLUCOSE_DOWN_h
Peng_et_al_2002
H009783_01
Info
KIAA0281 gene product
H009783_01
D87457
31463
KIAA0281

0.2322521
1.152
132
GLUCOSE_DOWN_h
Peng_et_al_2002
H002298_01
Info
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoinin
H002298_01
M30938
84981
XRCC5
Telomeres, Telomerase, Cellular Aging, and Immortality, DNA_damage, DNA_replication
0.2435454
1.101
133
GLUCOSE_DOWN_h
Peng_et_al_2002
H010810_01
Info
Splicing factor, arginine/serine-rich 1 (splicing factor 2, alternate splicing factor)
H010810_01
M72709
73737
SFRS1

0.2552533
0.909
134
GLUCOSE_DOWN_h
Peng_et_al_2002
H011501_01
Info
ADP-ribosylation factor 4
H011501_01
NM_001660
75290
ARF4

0.2579932
0.884
135
GLUCOSE_DOWN_h
Peng_et_al_2002
H001876_01
Info
3'-phosphoadenosine 5'-phosphosulfate synthase 1
H001876_01
AF105227
3833
PAPSS1
Purine metabolism, Selenoamino acid metabolism, Sulfur metabolism
0.2713835
0.89
136
GLUCOSE_DOWN_h
Peng_et_al_2002
H008985_01
Info
Eukaryotic translation initiation factor 3, subunit 3 (gamma, 40kD)
H008985_01
U54559
58189
EIF3S3

0.2852233
0.906
137
GLUCOSE_DOWN_h
Peng_et_al_2002
H001270_01
Info
Interferon, gamma-inducible protein 16
H001270_01
M63838
155530
IFI16
cell_signaling
0.2909837
1.116
138
GLUCOSE_DOWN_h
Peng_et_al_2002
H002973_01
Info
RAB1, member RAS oncogene family
H002973_01
M28209
3642
RAB1
Rab GTPases Mark Targets In The Endocytotic Machinery
0.292711
1.103
139
GLUCOSE_DOWN_h
Peng_et_al_2002
H003828_01
Info
Retinoblastoma-binding protein 4
H003828_01
X74262
16003
RBBP4
Mechanisms of transcriptional repression by DNA methylation, The PRC2 Complex Sets Long-term Gene Silencing Through Modification of Histone Tails
0.3028553
0.925
140
GLUCOSE_DOWN_h
Peng_et_al_2002
H002889_01
Info
Cyclin G1
H002889_01
X77794
79101
CCNG1

0.3030012
0.898
141
GLUCOSE_DOWN_h
Peng_et_al_2002
H003933_01
Info
General transcription factor IIA, 2 (12kD subunit)
H003933_01
U14193
76362
GTF2A2

0.3056055
0.899
142
GLUCOSE_DOWN_h
Peng_et_al_2002
H009033_01
Info
Neuromedin U
H009033_01
X76029
2841
NMU

0.3059932
1.152
143
GLUCOSE_DOWN_h
Peng_et_al_2002
H001344_01
Info
Fusion, derived from t(12;16) malignant liposarcoma
H001344_01
S62140
99969
FUS
misc
0.3107752
0.912
144
GLUCOSE_DOWN_h
Peng_et_al_2002
H012325_01
Info
Extra spindle poles, S. cerevisiae, homolog of
H012325_01
D79987
153479
KIAA0165

0.3223766
1.126
145
GLUCOSE_DOWN_h
Peng_et_al_2002
H008280_01
Info
Era (E. coli G-protein homolog)-like 1
H008280_01
AF082657
3426
ERAL1

0.326229
1.083
146
GLUCOSE_DOWN_h
Peng_et_al_2002
H001406_01
Info
Huntingtin interacting protein-1-related
H001406_01
AB014555
96731
KIAA0655

0.3265079
0.911
147
GLUCOSE_DOWN_h
Peng_et_al_2002
H000325_01
Info
Nuclear transcription factor Y, beta
H000325_01
X59710
84928
NFYB
Overview of telomerase RNA component gene hTerc Transcriptional Regulation
0.3282461
0.893
148
GLUCOSE_DOWN_h
Peng_et_al_2002
H002715_01
Info
Prohibitin
H002715_01
NM_002634
75323
PHB
immunology
0.3408704
0.898
149
GLUCOSE_DOWN_h
Peng_et_al_2002
H000723_01
Info
Angio-associated, migratory cell protein
H000723_01
M95627
83347
AAMP

0.3859087
0.934
150
GLUCOSE_DOWN_h
Peng_et_al_2002
H002782_01
Info
Wee1+ (S. pombe) homolog
H002782_01
X62048
75188
WEE1
cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G2/M Checkpoint, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, immunology
0.4033875
1.142
151
GLUCOSE_DOWN_h
Peng_et_al_2002
H012030_01
Info
Chromosome 1 open reading frame 8
H012030_01
AF047439
11441
C1ORF8

0.424321
0.929
152
GLUCOSE_DOWN_h
Peng_et_al_2002
H001314_01
Info
DEK oncogene (DNA binding)
H001314_01
X64229
110713
DEK

0.4424083
0.934
153
GLUCOSE_DOWN_h
Peng_et_al_2002
H008388_01
Info
Melanoma antigen, family D, 1
H008388_01
NM_006986
177556
MAGED1

0.4445493
0.9
154
GLUCOSE_DOWN_h
Peng_et_al_2002
H002127_01
Info
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
H002127_01
D86550
75842
DYRK1A
Sonic Hedgehog (Shh) Pathway
0.4628734
0.926
155
GLUCOSE_DOWN_h
Peng_et_al_2002
H008179_01
Info
PTD017 protein
H008179_01
AL050361
274417
PTD017

0.5042695
1.068
156
GLUCOSE_DOWN_h
Peng_et_al_2002
H013411_01
Info
Ribosomal protein, large P2
H013411_01
M17887
119500
RPLP2

0.5256547
1.063
157
GLUCOSE_DOWN_h
Peng_et_al_2002
H010641_01
Info
Bromodomain adjacent to zinc finger domain, 1A
H010641_01
AB032252
8858
BAZ1A

0.5315479
1.065
158
GLUCOSE_DOWN_h
Peng_et_al_2002
H011767_01
Info
SH2-B homolog
H011767_01
AB037720
15744
DKFZP547G1110

0.5793807
1.053
159
GLUCOSE_DOWN_h
Peng_et_al_2002
H008484_01
Info
Heterogeneous nuclear ribonucleoprotein R
H008484_01
AF000364
15265
HNRPR

0.5936826
1.065
160
GLUCOSE_DOWN_h
Peng_et_al_2002
H001516_01
Info
Guanosine monophosphate reductase
H001516_01
M24470
1435
GMPR
Purine metabolism
0.5998588
0.932
161
GLUCOSE_DOWN_h
Peng_et_al_2002
H001288_01
Info
ELL gene (11-19 lysine-rich leukemia gene)
H001288_01
U16282
5881
ELL

0.6032943
1.082
162
GLUCOSE_DOWN_h
Peng_et_al_2002
H001304_01
Info
ALL1-fused gene from chromosome 1q
H001304_01
U16954
75823
AF1Q
Perou's- Intrinsic- Breast-Cancer-Genes
0.603919
1.053
163
GLUCOSE_DOWN_h
Peng_et_al_2002
H012106_01
Info
Src-like-adapter
H012106_01
D89077
75367
SLA

0.6044071
0.939
164
GLUCOSE_DOWN_h
Peng_et_al_2002
H002217_01
Info
Dishevelled 3 (homologous to Drosophila dsh)
H002217_01
NM_004423
174044
DVL3
cell_signaling, signal_transduction
0.6065023
1.058
165
GLUCOSE_DOWN_h
Peng_et_al_2002
H011167_01
Info
HSPC035 protein
H011167_01
NM_016127
279921
LOC51669

0.6199261
1.046
166
GLUCOSE_DOWN_h
Peng_et_al_2002
H011548_01
Info
Fzr1 protein
H011548_01
AB033068
268384
FZR1

0.6646964
1.035
167
GLUCOSE_DOWN_h
Peng_et_al_2002
H002527_01
Info
Replication protein A3 (14kD)
H002527_01
L07493
1608
RPA3
DNA_replication
0.6875779
0.952
168
GLUCOSE_DOWN_h
Peng_et_al_2002
H000388_01
Info
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6
H000388_01
AL110183
73851
ATP5J
ATP synthesis, Oxidative phosphorylation, misc
0.7600099
0.953
169
GLUCOSE_DOWN_h
Peng_et_al_2002
H010946_01
Info
Artemin
H010946_01
AF109401
194689
ARTN

0.7609159
1.05
170
GLUCOSE_DOWN_h
Peng_et_al_2002
H009706_01
Info
RAB1, member RAS oncogene family
H009706_01
AL050268
3642
RAB1
Rab GTPases Mark Targets In The Endocytotic Machinery
0.7686339
0.971
171
GLUCOSE_DOWN_h
Peng_et_al_2002
H003482_01
Info
Catechol-O-methyltransferase
H003482_01
NM_000754
240013
COMT
Tyrosine metabolism, behavior, immunology
0.777803
1.026
172
GLUCOSE_DOWN_h
Peng_et_al_2002
H011214_01
Info
Williams-Beuren syndrome chromosome region 1
H011214_01
D26068
180900
WBSCR1

0.7785992
0.975
173
GLUCOSE_DOWN_h
Peng_et_al_2002
H012850_01
Info
Nucleosome assembly protein 1-like 1
H012850_01
AL162068
179662
NAP1L1

0.7805775
0.973
174
GLUCOSE_DOWN_h
Peng_et_al_2002
H007376_01
Info
Homo sapiens cDNA: FLJ22071 fis, clone HEP11691
H007376_01
AL049932
326248


0.785212
1.026
175
GLUCOSE_DOWN_h
Peng_et_al_2002
H007641_01
Info
Solute carrier family 12 (potassium/chloride transporters), member 4
H007641_01
AF054506
10094
SLC12A4

0.7951601
1.026
176
GLUCOSE_DOWN_h
Peng_et_al_2002
H001333_01
Info
Phosphatidylinositol binding clathrin assembly protein
H001333_01
U45976
7885
PICALM
Endocytotic role of NDK, Phosphins and Dynamin
0.8121842
0.978
177
GLUCOSE_DOWN_h
Peng_et_al_2002
H008039_01
Info
DnaJ (Hsp40) homolog, subfamily B, member 6
H008039_01
AB015798
181195
DNAJB6
Prion Pathway
0.8136927
1.024
178
GLUCOSE_DOWN_h
Peng_et_al_2002
H008319_01
Info
KIAA0461 protein
H008319_01
AB007930
107088
KIAA0461

0.8286286
1.017
179
GLUCOSE_DOWN_h
Peng_et_al_2002
H003056_01
Info
FOS-like antigen 2
H003056_01
X16706
301612
FOSL2
Bone Remodelling, tsonc
0.85065
1.018
180
GLUCOSE_DOWN_h
Peng_et_al_2002
H012188_01
Info
E2F transcription factor 4, p107/p130-binding
H012188_01
S75174
108371
E2F4
METS affect on Macrophage Differentiation
0.8845118
0.986
181
GLUCOSE_DOWN_h
Peng_et_al_2002
H000641_01
Info
Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
H000641_01
J02683
79172
SLC25A5

0.8966066
1.014
182
GLUCOSE_DOWN_h
Peng_et_al_2002
H012177_01
Info
SEC24 (S. cerevisiae) related gene family, member C
H012177_01
D38555
81964
SEC24C

0.9009444
0.987
183
GLUCOSE_DOWN_h
Peng_et_al_2002
H000555_01
Info
MAD2 (mitotic arrest deficient, yeast, homolog)-like 1
H000555_01
U65410
79078
MAD2L1
cell_cycle
0.9117596
1.012
184
GLUCOSE_DOWN_h
Peng_et_al_2002
H010542_01
Info
M-phase phosphoprotein homolog
H010542_01
NM_016107
173518
LOC51663

0.9533604
0.995
185
GLUCOSE_DOWN_h
Peng_et_al_2002
H001079_01
Info
Sodium channel, voltage-gated, type IV, alpha polypeptide
H001079_01
M81758
46038
SCN4A
immunology
0.9599901
1.005
186
GLUCOSE_DOWN_h
Peng_et_al_2002
H004613_01
Info
Telomeric repeat binding factor 2
H004613_01
AF002999
100030
TERF2
immunology
0.9802633
0.997
187
GLUCOSE_DOWN_h
Peng_et_al_2002
H002746_01
Info
TNF receptor-associated factor 5
H002746_01
AB000509
29736
TRAF5
TACI and BCMA stimulation of B cell immune responses., immunology
0.9871372
0.999
188
ghPathway_h
BioCarta
H000732_01
Info
Insulin receptor substrate 1
H000732_01
S62539
96063
IRS1
Perou's- Intrinsic- Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology
0.0013348
0.643
189
ghPathway_h
BioCarta
H002186_01
Info
Serum response factor (c-fos serum response element-binding transcription factor)
H002186_01
J03161
155321
SRF
EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription
0.0017465
0.722
190
ghPathway_h
BioCarta
H002055_01
Info
Growth factor receptor-bound protein 2
H002055_01
M96995
296381
GRB2
Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...
0.0022348
1.459
191
ghPathway_h
BioCarta
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
192
ghPathway_h
BioCarta
H002890_01
Info
Ribosomal protein S6 kinase, 90kD, polypeptide 1
H002890_01
L07597
149957
RPS6KA1
Cell Cycle: G2/M Checkpoint, Erk1/Erk2 Mapk Signaling pathway, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, MAPKinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Role of Erk5 in Neuronal Survival, Transcription factor CREB and its extracellular signals, Phosphatidylinositol signaling system
0.0138896
1.42
193
ghPathway_h
BioCarta
H001365_01
Info
Protein kinase C, beta 1
H001365_01
X07109
77202
PRKCB1
Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbal Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction
0.0304335
1.379
194
ghPathway_h
BioCarta
H003178_01
Info
Mitogen-activated protein kinase 3
H003178_01
X60188
861
MAPK3
Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...
0.0986041
1.184
195
ghPathway_h
BioCarta
H002624_01
Info
Insulin receptor
H002624_01
X02160
89695
INSR
Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Growth Hormone Signaling Pathway, Insulin Signaling Pathway, immunology
0.433218
0.919
196
ghPathway_h
BioCarta
H002261_01
Info
Signal transducer and activator of transcription 5B
H002261_01
U47686
244613
STAT5B

0.441402
1.071
197
ghPathway_h
BioCarta
H009068_01
Info
Homo sapiens mRNA; cDNA DKFZp586N1323 (from clone DKFZp586N1323)
H009068_01
AL080218
24064


0.509279
1.056
198
ghPathway_h
BioCarta
H002722_01
Info
Mitogen-activated protein kinase kinase 1
H002722_01
L11284
3446
MAP2K1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...
0.7377933
0.973
199
il2rbPathway_h
BioCarta
H000732_01
Info
Insulin receptor substrate 1
H000732_01
S62539
96063
IRS1
Perou's- Intrinsic- Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology
0.0013348
0.643
200
il2rbPathway_h
BioCarta
H000600_01
Info
STAT induced STAT inhibitor 3
H000600_01
AB004904
296176
SSI-3
IL-2 Receptor Beta Chain in T cell Activation, IL22 Soluble Receptor Signaling Pathway
0.0013931
0.69
201
il2rbPathway_h
BioCarta
H002055_01
Info
Growth factor receptor-bound protein 2
H002055_01
M96995
296381
GRB2
Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...
0.0022348
1.459
202
il2rbPathway_h
BioCarta
H000438_01
Info
CASP8 and FADD-like apoptosis regulator
H000438_01
Y14039
195175
CFLAR
FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, IL-2 Receptor Beta Chain in T cell Activation, Induction of apoptosis through DR3 and DR4/5 Death Receptors
0.00266
1.745
203
il2rbPathway_h
BioCarta
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
204
il2rbPathway_h
BioCarta
H003332_01
Info
V-crk avian sarcoma virus CT10 oncogene homolog-like
H003332_01
X59656
37078
CRKL
IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, Signaling of Hepatocyte Growth Factor Receptor, tsonc
0.0164206
0.675
205
il2rbPathway_h
BioCarta
H003305_01
Info
Ribosomal protein S6 kinase, 70kD, polypeptide 1
H003305_01
M60724
86858
RPS6KB1
CTCF: First Multivalent Nuclear Factor, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, MAPKinase Signaling Pathway, mTOR Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Rac 1 cell motility signaling pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction
0.0214523
1.448
206
il2rbPathway_h
BioCarta
H003718_01
Info
Interleukin 2 receptor, gamma (severe combined immunodeficiency)
H003718_01
D11086
84
IL2RG
IL 2 signaling pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, immunology
0.0314631
1.258
207
il2rbPathway_h
BioCarta
H013244_01
Info
N-myc (and STAT) interactor
H013244_01
U32849
54483
NMI
IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, signal_transduction
0.0799702
1.269
208
il2rbPathway_h
BioCarta
H003178_01
Info
Mitogen-activated protein kinase 3
H003178_01
X60188
861
MAPK3
Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...
0.0986041
1.184
209
il2rbPathway_h
BioCarta
H014546_01
Info
Peptidylprolyl isomerase A (cyclophilin A)
H014546_01
NM_021130
182937
PPIA
IL-2 Receptor Beta Chain in T cell Activation
0.129858
1.176
210
il2rbPathway_h
BioCarta
H002091_01
Info
V-myc avian myelocytomatosis viral oncogene homolog
H002091_01
K02276
79070
MYC
Cadmium induces DNA synthesis and proliferation in macrophages, CTCF: First Multivalent Nuclear Factor, Erk1/Erk2 Mapk Signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, MAPKinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, WNT Signaling Pathway, gene_regulation, immunology, transcription, tsonc
0.1797519
0.824
211
il2rbPathway_h
BioCarta
H003042_01
Info
BCL2-like 1
H003042_01
Z23115
305890
BCL2L1
Apoptotic Signaling in Response to DNA Damage, IL-2 Receptor Beta Chain in T cell Activation, Opposing roles of AIF in Apoptosis and Cell Survival, Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, immunology
0.2336065
1.143
212
il2rbPathway_h
BioCarta
H001349_01
Info
Janus kinase 1 (a protein tyrosine kinase)
H001349_01
M64174
50651
JAK1
EGF Signaling Pathway, IFN alpha signaling pathway, IFN gamma signaling pathway , IL 2 signaling pathway, IL 4 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, PDGF Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction
0.2754104
1.129
213
il2rbPathway_h
BioCarta
H002261_01
Info
Signal transducer and activator of transcription 5B
H002261_01
U47686
244613
STAT5B

0.441402
1.071
214
il2rbPathway_h
BioCarta
H003644_01
Info
Tumor necrosis factor receptor superfamily, member 6
H003644_01
X63717
82359
TNFRSF6
apoptosis, immunology
0.4621499
0.927
215
il2rbPathway_h
BioCarta
H002824_01
Info
Janus kinase 3 (a protein tyrosine kinase, leukocyte)
H002824_01
U09607
99877
JAK3
IL 2 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, IL22 Soluble Receptor Signaling Pathway , IL-7 Signal Transduction, Stat3 Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction
0.4735774
1.051
216
il2rbPathway_h
BioCarta
H009068_01
Info
Homo sapiens mRNA; cDNA DKFZp586N1323 (from clone DKFZp586N1323)
H009068_01
AL080218
24064


0.509279
1.056
217
il2rbPathway_h
BioCarta
H003650_01
Info
Interleukin 2 receptor, alpha
H003650_01
X01057
1724
IL2RA
IL 2 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Role of Tob in T-cell activation, Th1/Th2 Differentiation, immunology
0.5932248
1.054
218
il2rbPathway_h
BioCarta
H003612_01
Info
V-akt murine thymoma viral oncogene homolog 1
H003612_01
M63167
71816
AKT1
Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signalling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation ...
0.6741257
1.038
219
il2rbPathway_h
BioCarta
H001974_01
Info
BCL2-antagonist of cell death
H001974_01
U66879
76366
BAD
AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phosphoinositides and their downstream targets., Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Trefoil Factors Initiate Mucosal Healing, apoptosis, development
0.6985187
0.954
220
il2rbPathway_h
BioCarta
H015889_01
Info
BCL2-like 1
H015889_01
NM_001191
305890
BCL2L1
Apoptotic Signaling in Response to DNA Damage, IL-2 Receptor Beta Chain in T cell Activation, Opposing roles of AIF in Apoptosis and Cell Survival, Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, immunology
0.996743
1.001
221
ST_T_Cell_Signal_Transduction_h
Signalling Transduction KE
H001032_01
Info
Cytotoxic T-lymphocyte-associated protein 4
H001032_01
L15006
247824
CTLA4
The Co-Stimulatory Signal During T-cell Activation, immunology
0.0001134
0.56
222
ST_T_Cell_Signal_Transduction_h
Signalling Transduction KE
H008261_01
Info
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
H008261_01
Y12336
99491
RASGRP2

0.0002126
1.594
223
ST_T_Cell_Signal_Transduction_h
Signalling Transduction KE
H002055_01
Info
Growth factor receptor-bound protein 2
H002055_01
M96995
296381
GRB2
Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...
0.0022348
1.459
224
ST_T_Cell_Signal_Transduction_h
Signalling Transduction KE
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
225
ST_T_Cell_Signal_Transduction_h
Signalling Transduction KE
H003628_01
Info
Dystroglycan 1 (dystrophin-associated glycoprotein 1)
H003628_01
L19711
76111
DAG1
Agrin in Postsynaptic Differentiation, immunology
0.034627
0.774
226
ST_T_Cell_Signal_Transduction_h
Signalling Transduction KE
H003212_01
Info
Zeta-chain (TCR) associated protein kinase (70 kD)
H003212_01
L05148
234569
ZAP70
Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, Lck and Fyn tyrosine kinases in initiation of TCR Activation, T Cell Receptor Signaling Pathway, cell_cycle, cell_signaling, signal_transduction
0.0970422
0.833
227
ST_T_Cell_Signal_Transduction_h
Signalling Transduction KE
H002287_01
Info
P21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related)
H002287_01
U24152
62402
PAK1
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, FAS signaling pathway ( CD95 ), fMLP induced chemokine gene expression in HMC-1 cells, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Rac 1 cell motility signaling pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, TNFR1 Signaling Pathway
0.1104284
0.815
228
ST_T_Cell_Signal_Transduction_h
Signalling Transduction KE
H001748_01
Info
Inositol 1,4,5-trisphosphate 3-kinase B
H001748_01
X57206
78877
ITPKB
Inositol phosphate metabolism, Phosphatidylinositol signaling system, cell_signaling, signal_transduction
0.1283627
0.851
229
ST_T_Cell_Signal_Transduction_h
Signalling Transduction KE
H001718_01
Info
Inositol 1,4,5-trisphosphate 3-kinase A
H001718_01
X54938
2722
ITPKA
Inositol phosphate metabolism, Phosphatidylinositol signaling system
0.1331494
1.16
230
ST_T_Cell_Signal_Transduction_h
Signalling Transduction KE
H003550_01
Info
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
H003550_01
S76638
73090
NFKB2
gene_regulation, immunology, transcription, tsonc
0.1593331
1.165
231
ST_T_Cell_Signal_Transduction_h
Signalling Transduction KE
H011731_01
Info
P21 (CDKN1A)-activated kinase 3
H011731_01
AF068864
152663
PAK3
Phosphatidylinositol signaling system
0.1960548
1.141
232
ST_T_Cell_Signal_Transduction_h
Signalling Transduction KE
H003820_01
Info
Lymphocyte-specific protein tyrosine kinase
H003820_01
X05027
1765
LCK
Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, IL 2 signaling pathway, IL-7 Signal Transduction, Lck and Fyn tyrosine kinases in initiation of TCR Activation, T Cell Receptor Signaling Pathway, The Co-Stimulatory Signal During T-cell Activation, immunology, signal_transduction, tsonc
0.2266863
0.873
233
ST_T_Cell_Signal_Transduction_h
Signalling Transduction KE
H000543_01
Info
Linker for activation of T cells
H000543_01
AJ223280
83496
LAT
Ras-Independent pathway in NK cell-mediated cytotoxicity, T Cell Receptor Signaling Pathway
0.354745
0.903
234
ST_T_Cell_Signal_Transduction_h
Signalling Transduction KE
H013901_01
Info
Protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs
H013901_01
AB032968
20447
PAK4
Phosphatidylinositol signaling system
0.3636917
0.913
235
ST_T_Cell_Signal_Transduction_h
Signalling Transduction KE
H012554_01
Info
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
H012554_01
AF081195
182591
RASGRP1

0.3661482
0.901
236
ST_T_Cell_Signal_Transduction_h
Signalling Transduction KE
H015286_01
Info
Homo sapiens PAK2 mRNA, complete cds
H015286_01
AF092132
284275

FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, MAPKinase Signaling Pathway, TNFR1 Signaling Pathway, Phosphatidylinositol signaling system
0.4868167
1.068
237
ST_T_Cell_Signal_Transduction_h
Signalling Transduction KE
H008413_01
Info
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
H008413_01
X77909
2764
NFKBIL1

0.5281661
1.058
238
ST_T_Cell_Signal_Transduction_h
Signalling Transduction KE
H002812_01
Info
Protein tyrosine phosphatase, receptor type, C
H002812_01
Y00062
170121
PTPRC
Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, B Lymphocyte Cell Surface Molecules, Lck and Fyn tyrosine kinases in initiation of TCR Activation, T Cytotoxic Cell Surface Molecules, T Helper Cell Surface Molecules, cell_cycle, cell_signaling, immunology
0.6066202
1.093
239
ST_T_Cell_Signal_Transduction_h
Signalling Transduction KE
H003651_01
Info
EphB2
H003651_01
AF025304
125124
EPHB2
development
0.7855294
0.971
240
ST_T_Cell_Signal_Transduction_h
Signalling Transduction KE
H002447_01
Info
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
H002447_01
M69043
81328
NFKBIA
Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAPKinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, T Cell Receptor Signaling Pathway, The 4-1BB-dependent immune respon ...
0.8245205
0.975
241
ST_T_Cell_Signal_Transduction_h
Signalling Transduction KE
H012662_01
Info
Homo sapiens cDNA FLJ10205 fis, clone HEMBA1004954
H012662_01
AK001067
6226


0.8484663
1.017
242
ST_T_Cell_Signal_Transduction_h
Signalling Transduction KE
H003711_01
Info
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)
H003711_01
M58603
83428
NFKB1
Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAPKinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a ...
0.8665095
1.017
243
ST_T_Cell_Signal_Transduction_h
Signalling Transduction KE
H001340_01
Info
Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD)
H001340_01
U20158
2488
LCP2
immunology
0.9191876
1.009
244
ST_T_Cell_Signal_Transduction_h
Signalling Transduction KE
H003340_01
Info
C-src tyrosine kinase
H003340_01
X60114
77793
CSK
Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, Activation of Src by Protein-tyrosine phosphatase alpha, Cell to Cell Adhesion Signaling, Integrin Signaling Pathway, signal_transduction
0.9390319
1.008
245
pdgfPathway_h
BioCarta
H002186_01
Info
Serum response factor (c-fos serum response element-binding transcription factor)
H002186_01
J03161
155321
SRF
EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription
0.0017465
0.722
246
pdgfPathway_h
BioCarta
H002055_01
Info
Growth factor receptor-bound protein 2
H002055_01
M96995
296381
GRB2
Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...
0.0022348
1.459
247
pdgfPathway_h
BioCarta
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
248
pdgfPathway_h
BioCarta
H003611_01
Info
Mitogen-activated protein kinase kinase 4
H003611_01
L36870
75217
MAP2K4
Perou's- Intrinsic- Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system
0.012502
0.753
249
pdgfPathway_h
BioCarta
H001365_01
Info
Protein kinase C, beta 1
H001365_01
X07109
77202
PRKCB1
Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbal Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction
0.0304335
1.379
250
pdgfPathway_h
BioCarta
H003178_01
Info
Mitogen-activated protein kinase 3
H003178_01
X60188
861
MAPK3
Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...
0.0986041
1.184
251
pdgfPathway_h
BioCarta
H001600_01
Info
RAS p21 protein activator (GTPase activating protein) 1
H001600_01
M23379
758
RASA1
EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction
0.1015906
0.844
252
pdgfPathway_h
BioCarta
H003158_01
Info
Mitogen-activated protein kinase 8
H003158_01
L26318
190913
MAPK8
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...
0.1287835
1.166
253
pdgfPathway_h
BioCarta
H002775_01
Info
Platelet-derived growth factor receptor, alpha polypeptide
H002775_01
M21574
74615
PDGFRA
Perou's- Intrinsic- Breast-Cancer-Genes, CBL mediated ligand-induced downregulation of EGF receptors, Erk1/Erk2 Mapk Signaling pathway, PDGF Signaling Pathway, Phospholipids as signalling intermediaries, Rac 1 cell motility signaling pathway, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, immunology, signal_transduction
0.1636921
1.107
254
pdgfPathway_h
BioCarta
H001349_01
Info
Janus kinase 1 (a protein tyrosine kinase)
H001349_01
M64174
50651
JAK1
EGF Signaling Pathway, IFN alpha signaling pathway, IFN gamma signaling pathway , IL 2 signaling pathway, IL 4 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, PDGF Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction
0.2754104
1.129
255
pdgfPathway_h
BioCarta
H003231_01
Info
Platelet-derived growth factor alpha polypeptide
H003231_01
X06374
37040
PDGFA
Cytokines and Inflammatory Response, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), PDGF Signaling Pathway, Phospholipids as signalling intermediaries, immunology, misc, signal_transduction
0.6989894
1.039
256
pdgfPathway_h
BioCarta
H002722_01
Info
Mitogen-activated protein kinase kinase 1
H002722_01
L11284
3446
MAP2K1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...
0.7377933
0.973
257
igf1rPathway_h
BioCarta
H000732_01
Info
Insulin receptor substrate 1
H000732_01
S62539
96063
IRS1
Perou's- Intrinsic- Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology
0.0013348
0.643
258
igf1rPathway_h
BioCarta
H002055_01
Info
Growth factor receptor-bound protein 2
H002055_01
M96995
296381
GRB2
Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...
0.0022348
1.459
259
igf1rPathway_h
BioCarta
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
260
igf1rPathway_h
BioCarta
H002473_01
Info
Insulin-like growth factor 1 receptor
H002473_01
NM_000875
239176
IGF1R
Perou's- Intrinsic- Breast-Cancer-Genes, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Erk1/Erk2 Mapk Signaling pathway, IGF-1 Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Telomeres, Telomerase, Cellular Aging, and Immortality, The IGF-1 Receptor and Longevity, immunology
0.079692
1.158
261
igf1rPathway_h
BioCarta
H003178_01
Info
Mitogen-activated protein kinase 3
H003178_01
X60188
861
MAPK3
Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...
0.0986041
1.184
262
igf1rPathway_h
BioCarta
H003612_01
Info
V-akt murine thymoma viral oncogene homolog 1
H003612_01
M63167
71816
AKT1
Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signalling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation ...
0.6741257
1.038
263
igf1rPathway_h
BioCarta
H001974_01
Info
BCL2-antagonist of cell death
H001974_01
U66879
76366
BAD
AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phosphoinositides and their downstream targets., Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Trefoil Factors Initiate Mucosal Healing, apoptosis, development
0.6985187
0.954
264
igf1rPathway_h
BioCarta
H002722_01
Info
Mitogen-activated protein kinase kinase 1
H002722_01
L11284
3446
MAP2K1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...
0.7377933
0.973
265
MAPK_Cascade_h
GO
H003200_01
Info
Mitogen-activated protein kinase kinase 3
H003200_01
D87116
180533
MAP2K3
fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway
0.0009666
1.561
266
MAPK_Cascade_h
GO
H001648_01
Info
Myelin basic protein
H001648_01
M13577
69547
MBP

0.0014651
0.667
267
MAPK_Cascade_h
GO
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
268
MAPK_Cascade_h
GO
H002895_01
Info
Mitogen-activated protein kinase 14
H002895_01
L35263
79107
MAPK14
BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAPKinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm ...
0.0086925
1.429
269
MAPK_Cascade_h
GO
H003611_01
Info
Mitogen-activated protein kinase kinase 4
H003611_01
L36870
75217
MAP2K4
Perou's- Intrinsic- Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system
0.012502
0.753
270
MAPK_Cascade_h
GO
H003178_01
Info
Mitogen-activated protein kinase 3
H003178_01
X60188
861
MAPK3
Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...
0.0986041
1.184
271
MAPK_Cascade_h
GO
H000029_01
Info
Mitogen-activated protein kinase kinase kinase 3
H000029_01
U78876
29282
MAP3K3
MAPKinase Signaling Pathway, Phosphatidylinositol signaling system
0.2027051
1.138
272
MAPK_Cascade_h
GO
H002943_01
Info
V-raf murine sarcoma viral oncogene homolog B1
H002943_01
M95712
622
BRAF
MAPKinase Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction, tsonc
0.2376595
0.895
273
MAPK_Cascade_h
GO
H003309_01
Info
Mitogen-activated protein kinase kinase 7
H003309_01
AF013589
110299
MAP2K7
Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAPKinase Signaling Pathway
0.3044184
1.088
274
MAPK_Cascade_h
GO
H002722_01
Info
Mitogen-activated protein kinase kinase 1
H002722_01
L11284
3446
MAP2K1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...
0.7377933
0.973
275
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H002038_01
Info
Flavin containing monooxygenase 5
H002038_01
Z47553
14286
FMO5
Perou's- Intrinsic- Breast-Cancer-Genes
0.0001007
1.877
276
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H003352_01
Info
Interleukin 1 receptor, type I
H003352_01
M27492
82112
IL1R1
NF-kB Signaling Pathway, Signal transduction through IL1R, immunology
0.000502
0.677
277
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H000872_01
Info
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
H000872_01
AF104942
108660
ABCC5

0.00423
0.773
278
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H015306_01
Info
Core promoter element binding protein
H015306_01
NM_001300
285313
COPEB

0.0052134
1.473
279
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H000896_01
Info
Stanniocalcin 1
H000896_01
U25997
25590
STC1

0.0071618
0.726
280
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H001508_01
Info
Aldehyde dehydrogenase 4 family, member A1
H001508_01
U24266
77448
ALDH4A1
Catabolic Pathways for Arginine , Histidine, Glutamate, Glutamine, and Proline, Arginine and proline metabolism, Glutamate metabolism
0.0262657
0.769
281
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H002243_01
Info
Ras homolog gene family, member E
H002243_01
S82240
6838
ARHE
immunology
0.032366
1.421
282
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H003570_01
Info
Annexin A3
H003570_01
M20560
1378
ANXA3

0.049571
1.236
283
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H002515_01
Info
Clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed pro
H002515_01
M25915
75106
CLU
Perou's- Intrinsic- Breast-Cancer-Genes, immunology
0.0769494
0.829
284
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H001717_01
Info
RAP1, GTPase activating protein 1
H001717_01
M64788
75151
RAP1GA1

0.0888214
1.197
285
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H015322_01
Info
CD24 antigen (small cell lung carcinoma cluster 4 antigen)
H015322_01
NM_013230
286124
CD24
Perou's- Intrinsic- Breast-Cancer-Genes
0.0961671
1.127
286
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H007609_01
Info
Protein phosphatase 1, regulatory (inhibitor) subunit 5
H007609_01
Y18207
303090
PPP1R5

0.1045358
1.172
287
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H015668_01
Info
Parvalbumin
H015668_01
NM_002854
295449
PVALB

0.153268
0.857
288
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H009511_01
Info
Melanoma associated gene
H009511_01
D86983
118893
D2S448

0.1767501
0.81
289
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H008648_01
Info
Selenium binding protein 1
H008648_01
U29091
288973
SELENBP1
Perou's- Intrinsic- Breast-Cancer-Genes
0.2017613
1.203
290
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H001905_01
Info
LPS-induced TNF-alpha factor
H001905_01
NM_004862
76507
PIG7

0.2026162
1.209
291
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H003391_01
Info
Laminin, beta 1
H003391_01
NM_002291
82124
LAMB1
Prion Pathway
0.2163833
0.846
292
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H000262_01
Info
KIAA0307 gene product
H000262_01
AB002305
6111
KIAA0307

0.2604448
0.889
293
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H007445_01
Info
Homo sapiens cDNA FLJ20153 fis, clone COL08656, highly similar to AJ001381 Homo sapiens incomplete c
H007445_01
AK000160
121576


0.2652388
0.847
294
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H000651_01
Info
Mad4 homolog
H000651_01
AF040963
102402
MAD4

0.266447
0.891
295
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H000502_01
Info
Phosphoribosyl pyrophosphate synthetase 1
H000502_01
D00860
56
PRPS1
Histidine metabolism, Pentose phosphate pathway, Purine metabolism, gene_regulation, transcription
0.3045664
0.909
296
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H008715_01
Info
ATP-binding cassette, sub-family G (WHITE), member 1
H008715_01
X91249
10237
ABCG1
Nuclear Receptors in Lipid Metabolism and Toxicity
0.4098523
1.096
297
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H003763_01
Info
Folate hydrolase (prostate-specific membrane antigen) 1
H003763_01
M99487
1915
FOLH1

0.4171314
0.905
298
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H013236_01
Info
Monocyte to macrophage differentiation-associated
H013236_01
X85750
79889
MMD

0.4241064
0.921
299
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H003935_01
Info
KIAA0922 protein
H003935_01
AB023139
37892
KIAA0922

0.4306564
1.134
300
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H003371_01
Info
Erythropoietin receptor
H003371_01
NM_000121
89548
EPOR
Perou's- Intrinsic- Breast-Cancer-Genes, EPO Signaling Pathway, Erythropoietin mediated neuroprotection through NF-kB, immunology
0.4485722
0.93
301
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H005832_01
Info
Kynureninase (L-kynurenine hydrolase)
H005832_01
U57721
169139
KYNU
Tryptophan metabolism
0.5223633
1.074
302
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H011966_01
Info
Syntaxin binding protein 1
H011966_01
AF004563
239356
STXBP1

0.5388587
1.065
303
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H004814_01
Info
N-myc downstream regulated
H004814_01
D87953
75789
NDRG1

0.5742952
1.047
304
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H003024_01
Info
Cathepsin H
H003024_01
X16832
288181
CTSH
Perou's- Intrinsic- Breast-Cancer-Genes
0.5964026
1.048
305
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H001606_01
Info
Drebrin 1
H001606_01
AL110225
89434
DBN1

0.6301138
1.048
306
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H013890_01
Info
Slit (Drosophila) homolog 2
H013890_01
AF055585
29802
SLIT2

0.696259
0.965
307
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H000900_01
Info
Matrilin 2
H000900_01
AL137638
19368
MATN2

0.7034604
0.949
308
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H003542_01
Info
V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene
H003542_01
M11730
323910
ERBB2
Perou's- Intrinsic- Breast-Cancer-Genes, Role of ERBB2 in Signal Transduction and Oncology, Trefoil Factors Initiate Mucosal Healing, immunology, signal_transduction, tsonc
0.7160857
1.031
309
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H003155_01
Info
CD24 antigen (small cell lung carcinoma cluster 4 antigen)
H003155_01
L33930
286124
CD24
Perou's- Intrinsic- Breast-Cancer-Genes
0.7363586
0.966
310
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H003434_01
Info
Dual specificity phosphatase 1
H003434_01
NM_004417
171695
DUSP1
CD40L Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, TNFR2 Signaling Pathway
0.8183145
0.968
311
FRASOR_ER_DOWN_h
Frasor_et_al_2004
H001715_01
Info
Dual specificity phosphatase 4
H001715_01
AL137704
2359
DUSP4
Perou's- Intrinsic- Breast-Cancer-Genes, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, cell_cycle, cell_signaling
0.9634643
1.004
312
SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h
SignallingAlliance
H000732_01
Info
Insulin receptor substrate 1
H000732_01
S62539
96063
IRS1
Perou's- Intrinsic- Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology
0.0013348
0.643
313
SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h
SignallingAlliance
H002055_01
Info
Growth factor receptor-bound protein 2
H002055_01
M96995
296381
GRB2
Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...
0.0022348
1.459
314
SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h
SignallingAlliance
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
315
SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h
SignallingAlliance
H001348_01
Info
Phosphoinositide-3-kinase, catalytic, delta polypeptide
H001348_01
U86453
162808
PIK3CD
Inositol phosphate metabolism, Phosphatidylinositol signaling system
0.0324563
1.426
316
SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h
SignallingAlliance
H016134_01
Info
V-akt murine thymoma viral oncogene homolog 2
H016134_01
NM_001626
326445
AKT2
Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc
0.0530988
1.287
317
SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h
SignallingAlliance
H003178_01
Info
Mitogen-activated protein kinase 3
H003178_01
X60188
861
MAPK3
Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...
0.0986041
1.184
318
SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h
SignallingAlliance
H001349_01
Info
Janus kinase 1 (a protein tyrosine kinase)
H001349_01
M64174
50651
JAK1
EGF Signaling Pathway, IFN alpha signaling pathway, IFN gamma signaling pathway , IL 2 signaling pathway, IL 4 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, PDGF Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction
0.2754104
1.129
319
SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h
SignallingAlliance
H003497_01
Info
V-akt murine thymoma viral oncogene homolog 2
H003497_01
M77198
326445
AKT2
Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc
0.3314111
0.872
320
SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h
SignallingAlliance
H000650_01
Info
Glycogen synthase kinase 3 beta
H000650_01
L33801
78802
GSK3B
ALK in cardiac myocytes, Cell Cycle: G1/S Check Point , Deregulation of CDK5 in Alzheimers Disease, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Presenilin action in Notch and Wnt signaling, Regulation of eIF2, Segmentation Clock, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Sonic Hedgehog (Shh) Pathway, WNT Signaling Pathway, Phosphatidylinositol signaling system
0.353328
1.118
321
SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h
SignallingAlliance
H002824_01
Info
Janus kinase 3 (a protein tyrosine kinase, leukocyte)
H002824_01
U09607
99877
JAK3
IL 2 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, IL22 Soluble Receptor Signaling Pathway , IL-7 Signal Transduction, Stat3 Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction
0.4735774
1.051
322
SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h
SignallingAlliance
H002236_01
Info
Mitogen-activated protein kinase kinase kinase kinase 1
H002236_01
U66464
86575
MAP4K1
MAPKinase Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor, Phosphatidylinositol signaling system
0.5747172
0.927
323
SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h
SignallingAlliance
H003612_01
Info
V-akt murine thymoma viral oncogene homolog 1
H003612_01
M63167
71816
AKT1
Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signalling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation ...
0.6741257
1.038
324
SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h
SignallingAlliance
H001974_01
Info
BCL2-antagonist of cell death
H001974_01
U66879
76366
BAD
AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phosphoinositides and their downstream targets., Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Trefoil Factors Initiate Mucosal Healing, apoptosis, development
0.6985187
0.954
325
mapkPathway_h
BioCarta
H003200_01
Info
Mitogen-activated protein kinase kinase 3
H003200_01
D87116
180533
MAP2K3
fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway
0.0009666
1.561
326
mapkPathway_h
BioCarta
H002055_01
Info
Growth factor receptor-bound protein 2
H002055_01
M96995
296381
GRB2
Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...
0.0022348
1.459
327
mapkPathway_h
BioCarta
H003232_01
Info
Mitogen-activated protein kinase kinase kinase 14
H003232_01
Y10256
47007
MAP3K14
CD40L Signaling Pathway, Double Stranded RNA Induced Gene Expression, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Keratinocyte Differentiation, MAPKinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, TACI and BCMA stimulation of B cell immune responses., TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system
0.005309
0.755
328
mapkPathway_h
BioCarta
H002763_01
Info
Mitogen-activated protein kinase kinase kinase 8
H002763_01
D14497
248
MAP3K8
MAPKinase Signaling Pathway
0.005954
1.333
329
mapkPathway_h
BioCarta
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
330
mapkPathway_h
BioCarta
H002895_01
Info
Mitogen-activated protein kinase 14
H002895_01
L35263
79107
MAPK14
BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAPKinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm ...
0.0086925
1.429
331
mapkPathway_h
BioCarta
H002320_01
Info
Ribosomal protein S6 kinase, 70kD, polypeptide 2
H002320_01
AB016869
103081
RPS6KB2
MAPKinase Signaling Pathway
0.0093261
0.755
332
mapkPathway_h
BioCarta
H004176_01
Info
Mitogen-activated protein kinase kinase kinase 11
H004176_01
L32976
89449
MAP3K11
MAPKinase Signaling Pathway
0.0101996
1.263
333
mapkPathway_h
BioCarta
H003611_01
Info
Mitogen-activated protein kinase kinase 4
H003611_01
L36870
75217
MAP2K4
Perou's- Intrinsic- Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system
0.012502
0.753
334
mapkPathway_h
BioCarta
H003008_01
Info
Mitogen-activated protein kinase kinase kinase 4
H003008_01
AF002715
32353
MAP3K4
MAPKinase Signaling Pathway, Phosphatidylinositol signaling system
0.0127738
0.707
335
mapkPathway_h
BioCarta
H002890_01
Info
Ribosomal protein S6 kinase, 90kD, polypeptide 1
H002890_01
L07597
149957
RPS6KA1
Cell Cycle: G2/M Checkpoint, Erk1/Erk2 Mapk Signaling pathway, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, MAPKinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Role of Erk5 in Neuronal Survival, Transcription factor CREB and its extracellular signals, Phosphatidylinositol signaling system
0.0138896
1.42
336
mapkPathway_h
BioCarta
H003493_01
Info
MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B)
H003493_01
X63380
78881
MEF2B

0.0145042
1.328
337
mapkPathway_h
BioCarta
H001992_01
Info
Activating transcription factor 2
H001992_01
X15875
198166
ATF2
ALK in cardiac myocytes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , The 4-1BB-dependent immune response, The information-processing pathway at the IFN-beta enhancer
0.0178377
0.749
338
mapkPathway_h
BioCarta
H003305_01
Info
Ribosomal protein S6 kinase, 70kD, polypeptide 1
H003305_01
M60724
86858
RPS6KB1
CTCF: First Multivalent Nuclear Factor, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, MAPKinase Signaling Pathway, mTOR Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Rac 1 cell motility signaling pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction
0.0214523
1.448
339
mapkPathway_h
BioCarta
H000612_01
Info
Ribosomal protein S6 kinase, 90kD, polypeptide 3
H000612_01
U08316
173965
RPS6KA3
MAPKinase Signaling Pathway, Signaling Pathway from G-Protein Families, Phosphatidylinositol signaling system
0.0473043
0.79
340
mapkPathway_h
BioCarta
H003259_01
Info
Sp1 transcription factor
H003259_01
J03133
2021
SP1
Agrin in Postsynaptic Differentiation, Effects of calcineurin in Keratinocyte Differentiation, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, MAPKinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase protein component gene hTert Transcriptional Regulation , Overview of telomerase RNA component gene hTerc Transcriptional Regulation
0.0557417
0.814
341
mapkPathway_h
BioCarta
H011228_01
Info
G protein-coupled receptor kinase 7
H011228_01
AL137615
261828
GPRK7
Perou's- Intrinsic- Breast-Cancer-Genes, Erk1/Erk2 Mapk Signaling pathway, MAPKinase Signaling Pathway, Phosphatidylinositol signaling system
0.0572981
1.27
342
mapkPathway_h
BioCarta
H000521_01
Info
Ribosomal protein S6 kinase, 90kD, polypeptide 2
H000521_01
X85106
301664
RPS6KA2
MAPKinase Signaling Pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction
0.0604408
1.207
343
mapkPathway_h
BioCarta
H002588_01
Info
Mitogen-activated protein kinase 7
H002588_01
U29725
3080
MAPK7
Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), MAPKinase Signaling Pathway, Role of Erk5 in Neuronal Survival, Phosphatidylinositol signaling system
0.0614441
0.811
344
mapkPathway_h
BioCarta
H009683_01
Info
Mitogen-activated protein kinase kinase kinase kinase 4
H009683_01
AB014587
3628
MAP4K4
MAPKinase Signaling Pathway, Phosphatidylinositol signaling system
0.0707782
1.203
345
mapkPathway_h
BioCarta
H003107_01
Info
Mitogen-activated protein kinase 13
H003107_01
AF004709
178695
MAPK13
Keratinocyte Differentiation, MAPKinase Signaling Pathway, Stathmin and breast cancer resistance to antimicrotubule agents, Phosphatidylinositol signaling system
0.0717244
1.171
346
mapkPathway_h
BioCarta
H002049_01
Info
Death-associated protein 6
H002049_01
AB015051
180224
DAXX
FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , Regulation of transcriptional activity by PML, Stress Induction of HSP Regulation, apoptosis
0.0788021
1.159
347
mapkPathway_h
BioCarta
H003178_01
Info
Mitogen-activated protein kinase 3
H003178_01
X60188
861
MAPK3
Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...
0.0986041
1.184
348
mapkPathway_h
BioCarta
H002287_01
Info
P21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related)
H002287_01
U24152
62402
PAK1
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, FAS signaling pathway ( CD95 ), fMLP induced chemokine gene expression in HMC-1 cells, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Rac 1 cell motility signaling pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, TNFR1 Signaling Pathway
0.1104284
0.815
349
mapkPathway_h
BioCarta
H003158_01
Info
Mitogen-activated protein kinase 8
H003158_01
L26318
190913
MAPK8
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...
0.1287835
1.166
350
mapkPathway_h
BioCarta
H002091_01
Info
V-myc avian myelocytomatosis viral oncogene homolog
H002091_01
K02276
79070
MYC
Cadmium induces DNA synthesis and proliferation in macrophages, CTCF: First Multivalent Nuclear Factor, Erk1/Erk2 Mapk Signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, MAPKinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, WNT Signaling Pathway, gene_regulation, immunology, transcription, tsonc
0.1797519
0.824
351
mapkPathway_h
BioCarta
H002501_01
Info
Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
H002501_01
D25274
173737
RAC1
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signalling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments
0.1980127
1.118
352
mapkPathway_h
BioCarta
H000029_01
Info
Mitogen-activated protein kinase kinase kinase 3
H000029_01
U78876
29282
MAP3K3
MAPKinase Signaling Pathway, Phosphatidylinositol signaling system
0.2027051
1.138
353
mapkPathway_h
BioCarta
H002943_01
Info
V-raf murine sarcoma viral oncogene homolog B1
H002943_01
M95712
622
BRAF
MAPKinase Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction, tsonc
0.2376595
0.895
354
mapkPathway_h
BioCarta
H003309_01
Info
Mitogen-activated protein kinase kinase 7
H003309_01
AF013589
110299
MAP2K7
Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAPKinase Signaling Pathway
0.3044184
1.088
355
mapkPathway_h
BioCarta
H002405_01
Info
Mitogen-activated protein kinase kinase 2
H002405_01
L11285
72241
MAP2K2
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of ▀-arrestins in the activation and targeting of MAP kinases, Roles of ▀-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor
0.3118803
1.093
356
mapkPathway_h
BioCarta
H002660_01
Info
TNFRSF1A-associated via death domain
H002660_01
L41690
89862
TRADD
Acetylation and Deacetylation of RelA in The Nucleus, Ceramide Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , MAPKinase Signaling Pathway, NF-kB Signaling Pathway, p38 MAPK Signaling Pathway , SODD/TNFR1 Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway
0.3157474
1.092
357
mapkPathway_h
BioCarta
H002559_01
Info
Mitogen-activated protein kinase kinase kinase 12
H002559_01
U07358
211601
MAP3K12
MAPKinase Signaling Pathway, Phosphatidylinositol signaling system
0.3172697
1.101
358
mapkPathway_h
BioCarta
H000203_01
Info
MAX protein
H000203_01
X60287
42712
MAX
MAPKinase Signaling Pathway, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , gene_regulation, transcription, tsonc
0.3220945
1.09
359
mapkPathway_h
BioCarta
H002700_01
Info
Transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kD)
H002700_01
L11695
220
TGFBR1
ALK in cardiac myocytes, Function of SLRP in Bone: An Integrated View, MAPKinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, p38 MAPK Signaling Pathway , TGF beta signaling pathway, Phosphatidylinositol signaling system, angiogenesis, development
0.3279632
0.903
360
mapkPathway_h
BioCarta
H015286_01
Info
Homo sapiens PAK2 mRNA, complete cds
H015286_01
AF092132
284275

FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, MAPKinase Signaling Pathway, TNFR1 Signaling Pathway, Phosphatidylinositol signaling system
0.4868167
1.068
361
mapkPathway_h
BioCarta
H001369_01
Info
Ribosomal protein S6 kinase, 90kD, polypeptide 4
H001369_01
AJ010119
105584
RPS6KA4
MAPKinase Signaling Pathway, Phosphatidylinositol signaling system
0.5303179
0.95
362
mapkPathway_h
BioCarta
H002340_01
Info
Mitogen-activated protein kinase kinase kinase 5
H002340_01
U67156
151988
MAP3K5
HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , The 4-1BB-dependent immune response
0.5393151
1.07
363
mapkPathway_h
BioCarta
H002236_01
Info
Mitogen-activated protein kinase kinase kinase kinase 1
H002236_01
U66464
86575
MAP4K1
MAPKinase Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor, Phosphatidylinositol signaling system
0.5747172
0.927
364
mapkPathway_h
BioCarta
H010968_01
Info
Mitogen-activated protein kinase kinase kinase 6
H010968_01
AF100318
194694
MAP3K6
MAPKinase Signaling Pathway
0.6538459
1.04
365
mapkPathway_h
BioCarta
H001386_01
Info
Mitogen-activated protein kinase kinase kinase 10
H001386_01
X90846
30223
MAP3K10
MAPKinase Signaling Pathway, Phosphatidylinositol signaling system
0.7007387
0.968
366
mapkPathway_h
BioCarta
H002757_01
Info
Mitogen-activated protein kinase 6
H002757_01
X80692
271980
MAPK6
MAPKinase Signaling Pathway, Phosphatidylinositol signaling system
0.7279385
1.033
367
mapkPathway_h
BioCarta
H002722_01
Info
Mitogen-activated protein kinase kinase 1
H002722_01
L11284
3446
MAP2K1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...
0.7377933
0.973
368
mapkPathway_h
BioCarta
H002136_01
Info
Mitogen-activating protein kinase kinase kinase kinase 2
H002136_01
U07349
82979
MAP4K2
MAPKinase Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, TNF/Stress Related Signaling, Phosphatidylinositol signaling system
0.8239916
1.021
369
mapkPathway_h
BioCarta
H002447_01
Info
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
H002447_01
M69043
81328
NFKBIA
Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAPKinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, T Cell Receptor Signaling Pathway, The 4-1BB-dependent immune respon ...
0.8245205
0.975
370
mapkPathway_h
BioCarta
H002580_01
Info
Mitogen-activated protein kinase-activated protein kinase 3
H002580_01
U09578
227789
MAPKAPK3
MAPKinase Signaling Pathway, Stress Induction of HSP Regulation, immunology
0.8269383
0.981
371
mapkPathway_h
BioCarta
H001376_01
Info
Homo sapiens mRNA; cDNA DKFZp566L084 (from clone DKFZp566L084)
H001376_01
AL133012
306440

Acetylation and Deacetylation of RelA in The Nucleus, AKT Signaling Pathway, CD40L Signaling Pathway, Double Stranded RNA Induced Gene Expression, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAPKinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Ras Signaling Pathway, Signal transduction through IL1R, TACI and BCMA stimulation of B cell immune responses., The 4-1BB-dependent immune response, TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway, cell_cycle, cell_signaling, signal_transduction
0.8639394
0.98
372
mapkPathway_h
BioCarta
H003711_01
Info
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)
H003711_01
M58603
83428
NFKB1
Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAPKinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a ...
0.8665095
1.017
373
mapkPathway_h
BioCarta
H003860_01
Info
Mitogen-activated protein kinase kinase kinase kinase 5
H003860_01
U77129
246970
MAP4K5
MAPKinase Signaling Pathway, The 4-1BB-dependent immune response, Phosphatidylinositol signaling system
0.8968151
1.015
374
mapkPathway_h
BioCarta
H003773_01
Info
Mitogen-activated protein kinase 4
H003773_01
X59727
269222
MAPK4
MAPKinase Signaling Pathway, Phosphatidylinositol signaling system
0.91886
1.013
375
mapkPathway_h
BioCarta
H003163_01
Info
CAMP responsive element binding protein 1
H003163_01
M27691
79194
CREB1
Ca++/ Calmodulin-dependent Protein Kinase Activation, Calcium Signaling by HBx of Hepatitis B virus, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia-Inducible Factor in the Cardiovascular System, Inhibition of Huntington\'s disease neurodegeneration by histone deacetylase inhibitors, MAPKinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Repression of Pain Sensation by the Transcriptional Regulator DREAM, Role of Erk5 in Neuronal Survival, Signaling Pathway from G-Protein Families, Transcription factor CREB and its extracellular signals, Transcription Regulation by Methyltransferase of CARM1, immunology
0.9300928
1.009
376
mapkPathway_h
BioCarta
H012856_01
Info
MAP kinase-interacting serine/threonine kinase 1
H012856_01
AB000409
5591
MKNK1
Erk1/Erk2 Mapk Signaling pathway, MAPKinase Signaling Pathway, mTOR Signaling Pathway, p38 MAPK Signaling Pathway , Regulation of eIF4e and p70 S6 Kinase, Phosphatidylinositol signaling system
0.9455231
0.992
377
mapkPathway_h
BioCarta
H002963_01
Info
V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptid
H002963_01
L19067
75569
RELA
Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc
0.9724165
1.003
378
mapkPathway_h
BioCarta
H014820_01
Info
Mitogen-activated protein kinase 9
H014820_01
NM_002752
246857
MAPK9
MAPKinase Signaling Pathway, Phosphatidylinositol signaling system
0.9883614
0.998
379
MAP00010_Glycolysis_Gluconeogenesis_h
GenMAPP
H001935_01
Info
Glyceraldehyde-3-phosphate dehydrogenase
H001935_01
U34995
169476
GAPD

0.0001082
1.485
380
MAP00010_Glycolysis_Gluconeogenesis_h
GenMAPP
H002486_01
Info
Glucokinase (hexokinase 4, maturity onset diabetes of the young 2)
H002486_01
M90299
1270
GCK
Aminosugars metabolism, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Starch and sucrose metabolism, Streptomycin biosynthesis, immunology
0.0014569
1.288
381
MAP00010_Glycolysis_Gluconeogenesis_h
GenMAPP
H004823_01
Info
Aldolase C, fructose-bisphosphate
H004823_01
AF054987
155247
ALDOC
Carbon fixation, Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Inositol metabolism, Pentose phosphate pathway
0.001576
0.707
382
MAP00010_Glycolysis_Gluconeogenesis_h
GenMAPP
H003374_01
Info
Aldolase A, fructose-bisphosphate
H003374_01
M11560
273415
ALDOA
Downregulated of MTA-3 in ER-negative Breast Tumors, Carbon fixation, Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Inositol metabolism, Pentose phosphate pathway, immunology
0.0300936
1.252
383
MAP00010_Glycolysis_Gluconeogenesis_h
GenMAPP
H001878_01
Info
Enolase 1, (alpha)
H001878_01
M14328
254105
ENO1
Glycolysis Pathway, Glycolysis / Gluconeogenesis, Phenylalanine, tyrosine and tryptophan biosynthesis
0.0756084
1.187
384
MAP00010_Glycolysis_Gluconeogenesis_h
GenMAPP
H007138_01
Info
Phosphoglycerate kinase {alternatively spliced} [human, phosphoglycerate kinase deficient patient wi
H007138_01
S81916
169313

Glycolysis Pathway, Carbon fixation, Glycolysis / Gluconeogenesis, immunology
0.0923463
1.164
385
MAP00010_Glycolysis_Gluconeogenesis_h
GenMAPP
H001387_01
Info
Phosphofructokinase, platelet
H001387_01
D25328
99910
PFKP
Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology
0.101431
0.866
386
MAP00010_Glycolysis_Gluconeogenesis_h
GenMAPP
H001572_01
Info
Aldehyde dehydrogenase 3 family, member B2
H001572_01
U37519
87539
ALDH3B2
Glycolysis / Gluconeogenesis, Histidine metabolism, Phenylalanine metabolism, Tyrosine metabolism
0.1278934
0.831
387
MAP00010_Glycolysis_Gluconeogenesis_h
GenMAPP
H005470_01
Info
Homo sapiens mRNA; cDNA DKFZp762B245 (from clone DKFZp762B245); partial cds
H005470_01
AL162062
198182


0.1944956
1.125
388
MAP00010_Glycolysis_Gluconeogenesis_h
GenMAPP
H002972_01
Info
Lactate dehydrogenase A
H002972_01
X02152
2795
LDHA
Hypoxia-Inducible Factor in the Cardiovascular System, SARS Coronavirus Protease, Cysteine metabolism, Glycolysis / Gluconeogenesis, Propanoate metabolism, Pyruvate metabolism, immunology, misc
0.2007271
0.841
389
MAP00010_Glycolysis_Gluconeogenesis_h
GenMAPP
H003659_01
Info
Aldehyde dehydrogenase 3 family, member A2
H003659_01
U46689
159608
ALDH3A2
Perou's- Intrinsic- Breast-Cancer-Genes, Arginine and proline metabolism, Ascorbate and aldarate metabolism, beta-Alanine metabolism, Bile acid biosynthesis, Butanoate metabolism, Fatty acid metabolism, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Limonene and pinene degradation, Lysine degradation, Propanoate metabolism, Pyruvate metabolism, Tryptophan metabolism, Valine, leucine and isoleucine degradation
0.2326293
0.892
390
MAP00010_Glycolysis_Gluconeogenesis_h
GenMAPP
H001636_01
Info
Phosphoglycerate mutase 1 (brain)
H001636_01
J04173
181013
PGAM1
Glycolysis Pathway, Glycolysis / Gluconeogenesis, misc
0.2631445
1.109
391
MAP00010_Glycolysis_Gluconeogenesis_h
GenMAPP
H001378_01
Info
Phosphofructokinase, muscle
H001378_01
U24183
75160
PFKM
Phosphoinositides and their downstream targets., Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology
0.2927445
0.908
392
MAP00010_Glycolysis_Gluconeogenesis_h
GenMAPP
H001136_01
Info
Glucose-6-phosphatase, catalytic (glycogen storage disease type I, von Gierke disease)
H001136_01
U01120
242
G6PC
Galactose metabolism, Glycolysis / Gluconeogenesis, Starch and sucrose metabolism
0.3211576
0.901
393
MAP00010_Glycolysis_Gluconeogenesis_h
GenMAPP
H003068_01
Info
Pyruvate kinase, muscle
H003068_01
M26252
198281
PKM2
Carbon fixation, Glycolysis / Gluconeogenesis, Purine metabolism, Pyruvate metabolism
0.3246109
1.102
394
MAP00010_Glycolysis_Gluconeogenesis_h
GenMAPP
H000053_01
Info
BH3 interacting domain death agonist
H000053_01
AF042083
172894
BID
Apoptotic Signaling in Response to DNA Damage, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Role of Mitochondria in Apoptotic Signaling, immunology
0.4598136
1.076
395
MAP00010_Glycolysis_Gluconeogenesis_h
GenMAPP
H002609_01
Info
Aldehyde dehydrogenase 3 family, member B1
H002609_01
U10868
83155
ALDH3B1
Glycolysis / Gluconeogenesis, Histidine metabolism, Phenylalanine metabolism, Tyrosine metabolism
0.6584857
1.053
396
MAP00010_Glycolysis_Gluconeogenesis_h
GenMAPP
H001558_01
Info
Lactate dehydrogenase C
H001558_01
U13680
99881
LDHC

0.6951457
1.058
397
MAP00010_Glycolysis_Gluconeogenesis_h
GenMAPP
H003776_01
Info
Aldehyde dehydrogenase 2 family (mitochondrial)
H003776_01
X05409
195432
ALDH2
Arginine and proline metabolism, Ascorbate and aldarate metabolism, beta-Alanine metabolism, Bile acid biosynthesis, Butanoate metabolism, Fatty acid metabolism, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Limonene and pinene degradation, Lysine degradation, Propanoate metabolism, Pyruvate metabolism, Tryptophan metabolism, Valine, leucine and isoleucine degradation, immunology, pharmacology
0.7225282
0.971
398
MAP00010_Glycolysis_Gluconeogenesis_h
GenMAPP
H005249_01
Info
Homo sapiens 10q21 mRNA sequence
H005249_01
AF198444
279024

Arginine and proline metabolism, Ascorbate and aldarate metabolism, beta-Alanine metabolism, Bile acid biosynthesis, Butanoate metabolism, Fatty acid metabolism, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Limonene and pinene degradation, Lysine degradation, Phenylalanine metabolism, Propanoate metabolism, Pyruvate metabolism, Tryptophan metabolism, Tyrosine metabolism, Valine, leucine and isoleucine degradation
0.761598
0.965
399
MAP00010_Glycolysis_Gluconeogenesis_h
GenMAPP
H006795_01
Info
2,3-bisphosphoglycerate mutase
H006795_01
X04327
198365
BPGM
Glycolysis / Gluconeogenesis
0.8901914
1.013
400
MAP00010_Glycolysis_Gluconeogenesis_h
GenMAPP
H001385_01
Info
Phosphofructokinase, liver
H001385_01
X15573
155455
PFKL
Glycolysis Pathway, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology
0.9581627
1.005
401
MAP00010_Glycolysis_Gluconeogenesis_h
GenMAPP
H001547_01
Info
Aldehyde dehydrogenase 3 family, member A1
H001547_01
M74542
575
ALDH3A1
Arginine and proline metabolism, Ascorbate and aldarate metabolism, beta-Alanine metabolism, Bile acid biosynthesis, Butanoate metabolism, Fatty acid metabolism, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Limonene and pinene degradation, Lysine degradation, Phenylalanine metabolism, Propanoate metabolism, Pyruvate metabolism, Tryptophan metabolism, Tyrosine metabolism, Valine, leucine and isoleucine degradation
0.999646
1
402
pyk2Pathway_h
BioCarta
H003200_01
Info
Mitogen-activated protein kinase kinase 3
H003200_01
D87116
180533
MAP2K3
fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway
0.0009666
1.561
403
pyk2Pathway_h
BioCarta
H002055_01
Info
Growth factor receptor-bound protein 2
H002055_01
M96995
296381
GRB2
Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...
0.0022348
1.459
404
pyk2Pathway_h
BioCarta
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
405
pyk2Pathway_h
BioCarta
H002895_01
Info
Mitogen-activated protein kinase 14
H002895_01
L35263
79107
MAPK14
BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAPKinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm ...
0.0086925
1.429
406
pyk2Pathway_h
BioCarta
H002573_01
Info
Protein tyrosine kinase 2 beta
H002573_01
U43522
20313
PTK2B
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CXCR4 Signaling Pathway, IL-7 Signal Transduction, Ion Channel and Phorbal Esters Signaling Pathway, Links between Pyk2 and Map Kinases, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Thrombin signaling and protease-activated receptors, angiogenesis, immunology, signal_transduction
0.0091935
1.367
407
pyk2Pathway_h
BioCarta
H003611_01
Info
Mitogen-activated protein kinase kinase 4
H003611_01
L36870
75217
MAP2K4
Perou's- Intrinsic- Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system
0.012502
0.753
408
pyk2Pathway_h
BioCarta
H003332_01
Info
V-crk avian sarcoma virus CT10 oncogene homolog-like
H003332_01
X59656
37078
CRKL
IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, Signaling of Hepatocyte Growth Factor Receptor, tsonc
0.0164206
0.675
409
pyk2Pathway_h
BioCarta
H001365_01
Info
Protein kinase C, beta 1
H001365_01
X07109
77202
PRKCB1
Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbal Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction
0.0304335
1.379
410
pyk2Pathway_h
BioCarta
H003178_01
Info
Mitogen-activated protein kinase 3
H003178_01
X60188
861
MAPK3
Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...
0.0986041
1.184
411
pyk2Pathway_h
BioCarta
H002287_01
Info
P21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related)
H002287_01
U24152
62402
PAK1
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, FAS signaling pathway ( CD95 ), fMLP induced chemokine gene expression in HMC-1 cells, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Rac 1 cell motility signaling pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, TNFR1 Signaling Pathway
0.1104284
0.815
412
pyk2Pathway_h
BioCarta
H003158_01
Info
Mitogen-activated protein kinase 8
H003158_01
L26318
190913
MAPK8
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...
0.1287835
1.166
413
pyk2Pathway_h
BioCarta
H002501_01
Info
Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
H002501_01
D25274
173737
RAC1
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signalling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments
0.1980127
1.118
414
pyk2Pathway_h
BioCarta
H002405_01
Info
Mitogen-activated protein kinase kinase 2
H002405_01
L11285
72241
MAP2K2
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of ▀-arrestins in the activation and targeting of MAP kinases, Roles of ▀-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor
0.3118803
1.093
415
pyk2Pathway_h
BioCarta
H011336_01
Info
Guanine nucleotide binding protein (G protein), q polypeptide
H011336_01
U43083
296261
GNAQ
Activation of PKC through G protein coupled receptor, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CCR3 signaling in Eosinophils, CXCR4 Signaling Pathway, Effects of calcineurin in Keratinocyte Differentiation, G-Protein Signaling Through Tubby Proteins, Links between Pyk2 and Map Kinases, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase, Signaling Pathway from G-Protein Families, Thrombin signaling and protease-activated receptors, immunology
0.3713616
0.89
416
pyk2Pathway_h
BioCarta
H002722_01
Info
Mitogen-activated protein kinase kinase 1
H002722_01
L11284
3446
MAP2K1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...
0.7377933
0.973
417
pyk2Pathway_h
BioCarta
H002404_01
Info
Synaptotagmin I
H002404_01
M55047
154679
SYT1

0.8170962
0.971
418
pyk2Pathway_h
BioCarta
H000579_01
Info
Calmodulin 2 (phosphorylase kinase, delta)
H000579_01
D45887
182278
CALM2

0.9689776
1.004
419
mta3Pathway_h
BioCarta
H001935_01
Info
Glyceraldehyde-3-phosphate dehydrogenase
H001935_01
U34995
169476
GAPD

0.0001082
1.485
420
mta3Pathway_h
BioCarta
H002279_01
Info
Metastasis associated 1
H002279_01
U35113
101448
MTA1
Downregulated of MTA-3 in ER-negative Breast Tumors
0.0268932
0.814
421
mta3Pathway_h
BioCarta
H003374_01
Info
Aldolase A, fructose-bisphosphate
H003374_01
M11560
273415
ALDOA
Downregulated of MTA-3 in ER-negative Breast Tumors, Carbon fixation, Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Inositol metabolism, Pentose phosphate pathway, immunology
0.0300936
1.252
422
mta3Pathway_h
BioCarta
H015409_01
Info
Hypothetical protein FLJ13940
H015409_01
NM_025019
287610
FLJ13940

0.0928487
1.183
423
mta3Pathway_h
BioCarta
H003339_01
Info
Heat shock 27kD protein 2
H003339_01
D89617
78846
HSPB2

0.4094065
0.924
424
gata3Pathway_h
BioCarta
H003200_01
Info
Mitogen-activated protein kinase kinase 3
H003200_01
D87116
180533
MAP2K3
fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway
0.0009666
1.561
425
gata3Pathway_h
BioCarta
H002406_01
Info
Jun B proto-oncogene
H002406_01
X51345
198951
JUNB
GATA3 participate in activating the Th2 cytokine genes expression, tsonc
0.0021761
1.408
426
gata3Pathway_h
BioCarta
H003415_01
Info
Protein kinase, cAMP-dependent, catalytic, beta
H003415_01
M34181
87773
PRKACB
Perou's- Intrinsic- Breast-Cancer-Genes, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction
0.0048904
0.647
427
gata3Pathway_h
BioCarta
H002895_01
Info
Mitogen-activated protein kinase 14
H002895_01
L35263
79107
MAPK14
BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAPKinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm ...
0.0086925
1.429
428
gata3Pathway_h
BioCarta
H006601_01
Info
V-maf musculoaponeurotic fibrosarcoma (avian) oncogene homolog
H006601_01
AF055376
30250
MAF
GATA3 participate in activating the Th2 cytokine genes expression, tsonc
0.079493
0.812
429
gata3Pathway_h
BioCarta
H001698_01
Info
Protein kinase, cAMP-dependent, regulatory, type II, alpha
H001698_01
X14968
289075
PRKAR2A
AKAP95 role in mitosis and chromosome dynamics, Protein Kinase A at the Centrosome, Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation
0.2569617
1.125
430
gata3Pathway_h
BioCarta
H000645_01
Info
Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
H000645_01
M33336
183037
PRKAR1A
Activation of cAMP-dependent protein kinase, PKA, cell_cycle, cell_signaling, signal_transduction
0.4305614
0.935
431
gata3Pathway_h
BioCarta
H002045_01
Info
Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
H002045_01
U80917
96149
NFATC1
BCR Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Effects of calcineurin in Keratinocyte Differentiation, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Role of MEF2D in T-cell Apoptosis, Signaling Pathway from G-Protein Families, T Cell Receptor Signaling Pathway, immunology
0.623508
1.051
432
fcer1Pathway_h
In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.
H000403_01
Info
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
H000403_01
M33195
743
FCER1G
Fc Epsilon Receptor I Signaling in Mast Cells
0.0002683
2.278
433
fcer1Pathway_h
In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.
H002055_01
Info
Growth factor receptor-bound protein 2
H002055_01
M96995
296381
GRB2
Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...
0.0022348
1.459
434
fcer1Pathway_h
In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
435
fcer1Pathway_h
In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.
H002878_01
Info
V-yes-1 Yamaguchi sarcoma viral related oncogene homolog
H002878_01
M16038
80887
LYN
BCR Signaling Pathway, Eph Kinases and ephrins support platelet aggregation, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., immunology, signal_transduction, tsonc
0.0068841
1.545
436
fcer1Pathway_h
In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.
H003611_01
Info
Mitogen-activated protein kinase kinase 4
H003611_01
L36870
75217
MAP2K4
Perou's- Intrinsic- Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system
0.012502
0.753
437
fcer1Pathway_h
In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.
H001365_01
Info
Protein kinase C, beta 1
H001365_01
X07109
77202
PRKCB1
Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbal Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction
0.0304335
1.379
438
fcer1Pathway_h
In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.
H003178_01
Info
Mitogen-activated protein kinase 3
H003178_01
X60188
861
MAPK3
Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...
0.0986041
1.184
439
fcer1Pathway_h
In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.
H003158_01
Info
Mitogen-activated protein kinase 8
H003158_01
L26318
190913
MAPK8
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...
0.1287835
1.166
440
fcer1Pathway_h
In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.
H003870_01
Info
Bruton agammaglobulinemia tyrosine kinase
H003870_01
NM_000061
159494
BTK
BCR Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., cell_cycle, cell_signaling, immunology, signal_transduction
0.251649
1.148
441
fcer1Pathway_h
In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.
H003309_01
Info
Mitogen-activated protein kinase kinase 7
H003309_01
AF013589
110299
MAP2K7
Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAPKinase Signaling Pathway
0.3044184
1.088
442
fcer1Pathway_h
In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.
H001979_01
Info
Protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta)
H001979_01
M29551
151531
PPP3CB
cell_cycle, cell_signaling
0.3386238
0.898
443
fcer1Pathway_h
In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.
H015286_01
Info
Homo sapiens PAK2 mRNA, complete cds
H015286_01
AF092132
284275

FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, MAPKinase Signaling Pathway, TNFR1 Signaling Pathway, Phosphatidylinositol signaling system
0.4868167
1.068
444
fcer1Pathway_h
In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.
H003578_01
Info
Protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma)
H003578_01
S46622
75206
PPP3CC

0.5197011
0.934
445
fcer1Pathway_h
In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.
H002045_01
Info
Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
H002045_01
U80917
96149
NFATC1
BCR Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Effects of calcineurin in Keratinocyte Differentiation, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Role of MEF2D in T-cell Apoptosis, Signaling Pathway from G-Protein Families, T Cell Receptor Signaling Pathway, immunology
0.623508
1.051
446
fcer1Pathway_h
In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.
H000983_01
Info
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
H000983_01
X06948
897
FCER1A
Fc Epsilon Receptor I Signaling in Mast Cells, immunology
0.6468177
0.954
447
fcer1Pathway_h
In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.
H002470_01
Info
Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
H002470_01
L41067
172674
NFATC3
immunology
0.7190859
0.97
448
fcer1Pathway_h
In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.
H002722_01
Info
Mitogen-activated protein kinase kinase 1
H002722_01
L11284
3446
MAP2K1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...
0.7377933
0.973
449
fcer1Pathway_h
In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.
H002404_01
Info
Synaptotagmin I
H002404_01
M55047
154679
SYT1

0.8170962
0.971
450
fcer1Pathway_h
In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.
H000579_01
Info
Calmodulin 2 (phosphorylase kinase, delta)
H000579_01
D45887
182278
CALM2

0.9689776
1.004
451
metPathway_h
BioCarta
H002055_01
Info
Growth factor receptor-bound protein 2
H002055_01
M96995
296381
GRB2
Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel ...
0.0022348
1.459
452
metPathway_h
BioCarta
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
453
metPathway_h
BioCarta
H002573_01
Info
Protein tyrosine kinase 2 beta
H002573_01
U43522
20313
PTK2B
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CXCR4 Signaling Pathway, IL-7 Signal Transduction, Ion Channel and Phorbal Esters Signaling Pathway, Links between Pyk2 and Map Kinases, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Thrombin signaling and protease-activated receptors, angiogenesis, immunology, signal_transduction
0.0091935
1.367
454
metPathway_h
BioCarta
H003332_01
Info
V-crk avian sarcoma virus CT10 oncogene homolog-like
H003332_01
X59656
37078
CRKL
IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, Signaling of Hepatocyte Growth Factor Receptor, tsonc
0.0164206
0.675
455
metPathway_h
BioCarta
H003178_01
Info
Mitogen-activated protein kinase 3
H003178_01
X60188
861
MAPK3
Perou's- Intrinsic- Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho ...
0.0986041
1.184
456
metPathway_h
BioCarta
H001600_01
Info
RAS p21 protein activator (GTPase activating protein) 1
H001600_01
M23379
758
RASA1
EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction
0.1015906
0.844
457
metPathway_h
BioCarta
H002287_01
Info
P21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related)
H002287_01
U24152
62402
PAK1
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, FAS signaling pathway ( CD95 ), fMLP induced chemokine gene expression in HMC-1 cells, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Rac 1 cell motility signaling pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, TNFR1 Signaling Pathway
0.1104284
0.815
458
metPathway_h
BioCarta
H003158_01
Info
Mitogen-activated protein kinase 8
H003158_01
L26318
190913
MAPK8
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...
0.1287835
1.166
459
metPathway_h
BioCarta
H002112_01
Info
PTK2 protein tyrosine kinase 2
H002112_01
L13616
740
PTK2
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Apoptotic Signaling in Response to DNA Damage, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, CCR3 signaling in Eosinophils, Cell to Cell Adhesion Signaling, CXCR4 Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, HIV-I Nef: negative effector of Fas and TNF, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Phospholipids as signalling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Trefoil Factors Initiate Mucosal Healing, uCalpain and friends in Cell spread, VEGF, Hypoxia, and Angiogenesis, angiogenesis, signal_transduction
0.2346929
0.896
460
metPathway_h
BioCarta
H002632_01
Info
GRB2-associated binding protein 1
H002632_01
U43885
239706
GAB1
Signaling of Hepatocyte Growth Factor Receptor
0.3021702
1.095
461
metPathway_h
BioCarta
H002405_01
Info
Mitogen-activated protein kinase kinase 2
H002405_01
L11285
72241
MAP2K2
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of ▀-arrestins in the activation and targeting of MAP kinases, Roles of ▀-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor
0.3118803
1.093
462
metPathway_h
BioCarta
H000015_01
Info
Dedicator of cyto-kinesis 1
H000015_01
D50857
82295
DOCK1
Signaling of Hepatocyte Growth Factor Receptor, immunology
0.334442
0.886
463
metPathway_h
BioCarta
H003533_01
Info
Paxillin
H003533_01
U14588
102497
PXN
Agrin in Postsynaptic Differentiation, Apoptotic Signaling in Response to DNA Damage, Cell to Cell Adhesion Signaling, CXCR4 Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Signaling of Hepatocyte Growth Factor Receptor, uCalpain and friends in Cell spread, VEGF, Hypoxia, and Angiogenesis, immunology
0.4629128
1.067
464
metPathway_h
BioCarta
H002236_01
Info
Mitogen-activated protein kinase kinase kinase kinase 1
H002236_01
U66464
86575
MAP4K1
MAPKinase Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor, Phosphatidylinositol signaling system
0.5747172
0.927
465
metPathway_h
BioCarta
H002722_01
Info
Mitogen-activated protein kinase kinase 1
H002722_01
L11284
3446
MAP2K1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...
0.7377933
0.973
466
metPathway_h
BioCarta
H003724_01
Info
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
H003724_01
NM_002211
202661
ITGB1
Adhesion and Diapedesis of Lymphocytes, Adhesion Molecules on Lymphocyte, Agrin in Postsynaptic Differentiation, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, B Cell Survival Pathway, Cells and Molecules involved in local acute inflammatory response, Eph Kinases and ephrins support platelet aggregation, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Monocyte and its Surface Molecules, PTEN dependent cell cycle arrest and apoptosis, Ras-Independent pathway in NK cell-mediated cytotoxicity, Signaling of Hepatocyte Growth Factor Receptor, Trefoil Factors Initiate Mucosal Healing, uCalpain and friends in Cell spread, cell_signaling, immunology, metastasis
0.9378203
0.993
467
cell_motility_h
Any process involved in the controlled movement of a cell.
H002800_01
Info
Connective tissue growth factor
H002800_01
X78947
75511
CTGF
immunology, misc
0.0004011
0.555
468
cell_motility_h
Any process involved in the controlled movement of a cell.
H002931_01
Info
Selectin L (lymphocyte adhesion molecule 1)
H002931_01
M25280
82848
SELL
Adhesion and Diapedesis of Granulocytes, Adhesion and Diapedesis of Lymphocytes, Adhesion Molecules on Lymphocyte, Monocyte and its Surface Molecules, Neutrophil and Its Surface Molecules, cell_signaling, immunology, metastasis
0.0013165
2.024
469
cell_motility_h
Any process involved in the controlled movement of a cell.
H002895_01
Info
Mitogen-activated protein kinase 14
H002895_01
L35263
79107
MAPK14
BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAPKinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm ...
0.0086925
1.429
470
cell_motility_h
Any process involved in the controlled movement of a cell.
H000459_01
Info
Serine protease inhibitor, Kunitz type, 2
H000459_01
AF027205
31439
SPINT2

0.009031
0.736
471
cell_motility_h
Any process involved in the controlled movement of a cell.
H002944_01
Info
Interleukin 8
H002944_01
M17017
624
IL8
Adhesion and Diapedesis of Granulocytes, Adhesion and Diapedesis of Lymphocytes, Cells and Molecules involved in local acute inflammatory response, Cytokine Network, Cytokines and Inflammatory Response, Free Radical Induced Apoptosis, IL 17 Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Proepithelin Conversion to Epithelin and Wound Repair Control, Regulation of hematopoiesis by cytokines, immunology
0.0100881
0.681
472
cell_motility_h
Any process involved in the controlled movement of a cell.
H003332_01
Info
V-crk avian sarcoma virus CT10 oncogene homolog-like
H003332_01
X59656
37078
CRKL
IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, Signaling of Hepatocyte Growth Factor Receptor, tsonc
0.0164206
0.675
473
cell_motility_h
Any process involved in the controlled movement of a cell.
H000633_01
Info
Coronin, actin-binding protein, 1A
H000633_01
D44497
109606
CORO1A

0.0167926
1.342
474
cell_motility_h
Any process involved in the controlled movement of a cell.
H002936_01
Info
Macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
H002936_01
X70040
2942
MST1R
Msp/Ron Receptor Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction
0.0189711
0.747
475
cell_motility_h
Any process involved in the controlled movement of a cell.
H004577_01
Info
Vasodilator-stimulated phosphoprotein
H004577_01
Z46389
93183
VASP
cell_signaling, immunology, signal_transduction
0.0236006
1.288
476
cell_motility_h
Any process involved in the controlled movement of a cell.
H004361_01
Info
Homo sapiens thioredoxin delta 3 (TXN delta 3) mRNA, partial cds
H004361_01
AF065241
306243

Chaperones modulate interferon Signaling Pathway, immunology
0.028408
1.271
477
cell_motility_h
Any process involved in the controlled movement of a cell.
H002347_01
Info
Leukotriene b4 receptor (chemokine receptor-like 1)
H002347_01
D89078
28408
LTB4R
immunology
0.0284508
1.35
478
cell_motility_h
Any process involved in the controlled movement of a cell.
H002869_01
Info
Platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD)
H002869_01
NM_000430
77318
PAFAH1B1
Glycerophospholipid metabolism, immunology
0.0323993
0.822
479
cell_motility_h
Any process involved in the controlled movement of a cell.
H003130_01
Info
Interleukin 8 receptor, beta
H003130_01
L19593
846
IL8RB
immunology
0.0345675
1.307
480
cell_motility_h
Any process involved in the controlled movement of a cell.
H001342_01
Info
Lymphocyte-specific protein 1
H001342_01
M33552
56729
LSP1
immunology
0.0390011
1.407
481
cell_motility_h
Any process involved in the controlled movement of a cell.
H015282_01
Info
Dynein, axonemal, heavy polypeptide 9
H015282_01
AJ404468
284259
DNAH9

0.0393936
1.221
482
cell_motility_h
Any process involved in the controlled movement of a cell.
H005850_01
Info
Dynein, axonemal, heavy polypeptide 17-like
H005850_01
AB002355
169148
DNAH17L

0.0500062
1.217
483
cell_motility_h
Any process involved in the controlled movement of a cell.
H012622_01
Info
Actin related protein 2/3 complex, subunit 1A (41 kD)
H012622_01
AF006084
11538
ARPC1B

0.0686508
1.204
484
cell_motility_h
Any process involved in the controlled movement of a cell.
H001765_01
Info
Myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L)
H001765_01
D10522
75607
MACS
Effects of calcineurin in Keratinocyte Differentiation
0.1075359
1.166
485
cell_motility_h
Any process involved in the controlled movement of a cell.
H002937_01
Info
Fibronectin 1
H002937_01
X02761
287820
FN1
angiogenesis, cell_signaling, immunology, metastasis
0.128354
1.194
486
cell_motility_h
Any process involved in the controlled movement of a cell.
H003158_01
Info
Mitogen-activated protein kinase 8
H003158_01
L26318
190913
MAPK8
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...
0.1287835
1.166
487
cell_motility_h
Any process involved in the controlled movement of a cell.
H000967_01
Info
Thrombospondin 4
H000967_01
Z19585
75774
THBS4
angiogenesis
0.1424962
0.85
488
cell_motility_h
Any process involved in the controlled movement of a cell.
H015328_01
Info
Junctional adhesion molecule
H015328_01
AF172398
286218
JAM
Perou's- Intrinsic- Breast-Cancer-Genes
0.1497802
1.165
489
cell_motility_h
Any process involved in the controlled movement of a cell.
H011553_01
Info
Katanin p80 (WD40-containing) subunit B 1
H011553_01
AF052432
275675
KATNB1

0.1512807
0.867
490
cell_motility_h
Any process involved in the controlled movement of a cell.
H003564_01
Info
Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
H003564_01
AB002329
212414
SEMA3E

0.1517956
0.885
491
cell_motility_h
Any process involved in the controlled movement of a cell.
H002110_01
Info
Coagulation factor II (thrombin) receptor
H002110_01
NM_001992
128087
F2R
Perou's- Intrinsic- Breast-Cancer-Genes, Acute Myocardial Infarction, Extrinsic Prothrombin Activation Pathway, Fibrinolysis Pathway, Intrinsic Prothrombin Activation Pathway, immunology
0.1560498
0.883
492
cell_motility_h
Any process involved in the controlled movement of a cell.
H002501_01
Info
Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
H002501_01
D25274
173737
RAC1
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signalling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments
0.1980127
1.118
493
cell_motility_h
Any process involved in the controlled movement of a cell.
H002477_01
Info
Neogenin (chicken) homolog 1
H002477_01
U61262
90408
NEO1
angiogenesis, metastasis
0.2084414
1.135
494
cell_motility_h
Any process involved in the controlled movement of a cell.
H002750_01
Info
Neuropeptide Y
H002750_01
K01911
1832
NPY

0.2221305
1.126
495
cell_motility_h
Any process involved in the controlled movement of a cell.
H010731_01
Info
Partner of RAC1 (arfaptin 2)
H010731_01
U52522
75139
POR1
Rac 1 cell motility signaling pathway
0.259825
0.88
496
cell_motility_h
Any process involved in the controlled movement of a cell.
H007632_01
Info
Type I transmembrane protein Fn14
H007632_01
AB035480
10086
FN14

0.2727261
0.885
497
cell_motility_h
Any process involved in the controlled movement of a cell.
H005765_01
Info
A kinase (PRKA) anchor protein 3
H005765_01
NM_006422
98397
AKAP3

0.2830261
1.114
498
cell_motility_h
Any process involved in the controlled movement of a cell.
H005714_01
Info
A kinase (PRKA) anchor protein 4
H005714_01
AF072756
97633
AKAP4

0.284392
1.108
499
cell_motility_h
Any process involved in the controlled movement of a cell.
H000220_01
Info
Guanine nucleotide binding protein (G protein), alpha 13
H000220_01
L22075
1666
GNA13
PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase, Thrombin signaling and protease-activated receptors
0.2922764
1.182
500
cell_motility_h
Any process involved in the controlled movement of a cell.
H013061_01
Info
Cerebral cell adhesion molecule
H013061_01
NM_016174
23954
LOC51148

0.3332267
0.884
501
cell_motility_h
Any process involved in the controlled movement of a cell.
H002922_01
Info
Annexin A1
H002922_01
X05908
78225
ANXA1
Corticosteroids and cardioprotection
0.348625
1.12
502
cell_motility_h
Any process involved in the controlled movement of a cell.
H013901_01
Info
Protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs
H013901_01
AB032968
20447
PAK4
Phosphatidylinositol signaling system
0.3636917
0.913
503
cell_motility_h
Any process involved in the controlled movement of a cell.
H000723_01
Info
Angio-associated, migratory cell protein
H000723_01
M95627
83347
AAMP

0.3859087
0.934
504
cell_motility_h
Any process involved in the controlled movement of a cell.
H002976_01
Info
G protein-coupled receptor 9
H002976_01
X95876
198252
GPR9
IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, mCalpain and friends in Cell motility, NO2-dependent IL 12 Pathway in NK cells, Selective expression of chemokine receptors during T-cell polarization
0.4390046
0.918
505
cell_motility_h
Any process involved in the controlled movement of a cell.
H013376_01
Info
Capping protein (actin filament) muscle Z-line, alpha 2
H013376_01
U03851
75546
CAPZA2

0.4421974
1.117
506
cell_motility_h
Any process involved in the controlled movement of a cell.
H011225_01
Info
Serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 2
H011225_01
AB006423
158308
SERPINI2

0.4705964
0.919
507
cell_motility_h
Any process involved in the controlled movement of a cell.
H004767_01
Info
Tetraspan 3
H004767_01
AK001326
100090
TSPAN-3

0.4723725
1.074
508
cell_motility_h
Any process involved in the controlled movement of a cell.
H015920_01
Info
Homo sapiens thioredoxin delta 3 (TXN delta 3) mRNA, partial cds
H015920_01
AF065241
306243

Chaperones modulate interferon Signaling Pathway, immunology
0.5292008
1.077
509
cell_motility_h
Any process involved in the controlled movement of a cell.
H010773_01
Info
Actin related protein 2/3 complex, subunit 4 (20 kD)
H010773_01
AF006087
323342
ARPC4

0.5595709
0.946
510
cell_motility_h
Any process involved in the controlled movement of a cell.
H000791_01
Info
Platelet-activating factor acetylhydrolase, isoform Ib, beta subunit (30kD)
H000791_01
D63390
93354
PAFAH1B2
immunology
0.5668546
0.933
511
cell_motility_h
Any process involved in the controlled movement of a cell.
H003496_01
Info
Small inducible cytokine subfamily B (Cys-X-Cys), member 10
H003496_01
X02530
2248
SCYB10

0.572348
1.053
512
cell_motility_h
Any process involved in the controlled movement of a cell.
H007284_01
Info
Chondroitin sulfate proteoglycan 4 (melanoma-associated)
H007284_01
X96753
9004
CSPG4

0.6004302
0.95
513
cell_motility_h
Any process involved in the controlled movement of a cell.
H003538_01
Info
Actin, beta
H003538_01
NM_001101
288061
ACTB
Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes
0.6253266
0.956
514
cell_motility_h
Any process involved in the controlled movement of a cell.
H003708_01
Info
Thioredoxin
H003708_01
X77584
76136
TXN
Chaperones modulate interferon Signaling Pathway, immunology
0.6582476
1.041
515
cell_motility_h
Any process involved in the controlled movement of a cell.
H002722_01
Info
Mitogen-activated protein kinase kinase 1
H002722_01
L11284
3446
MAP2K1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas ...
0.7377933
0.973
516
cell_motility_h
Any process involved in the controlled movement of a cell.
H006937_01
Info
Hypothetical protein FLJ10211
H006937_01
AK001073
274206
FLJ10211

0.8108637
0.973
517
cell_motility_h
Any process involved in the controlled movement of a cell.
H006776_01
Info
Tetraspan 1
H006776_01
AF065388
38972
TSPAN-1

0.819954
1.022
518
cell_motility_h
Any process involved in the controlled movement of a cell.
H013182_01
Info
ARP2 (actin-related protein 2, yeast) homolog
H013182_01
AF006082
42915
ACTR2

0.840062
0.978
519
cell_motility_h
Any process involved in the controlled movement of a cell.
H007017_01
Info
Extracellular link domain-containing 1
H007017_01
NM_006691
17917
XLKD1

0.841013
0.971
520
cell_motility_h
Any process involved in the controlled movement of a cell.
H011434_01
Info
ARP3 (actin-related protein 3, yeast) homolog
H011434_01
NM_005721
5321
ACTR3

0.8741333
1.017
521
cell_motility_h
Any process involved in the controlled movement of a cell.
H003854_01
Info
Burkitt lymphoma receptor 1, GTP-binding protein
H003854_01
X68149
113916
BLR1

0.882872
0.982
522
cell_motility_h
Any process involved in the controlled movement of a cell.
H002891_01
Info
Small inducible cytokine A4 (homologous to mouse Mip-1b)
H002891_01
J04130
75703
SCYA4
Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Selective expression of chemokine receptors during T-cell polarization
0.8975649
1.014
523
cell_motility_h
Any process involved in the controlled movement of a cell.
H000822_01
Info
Filamin A, alpha (actin-binding protein-280)
H000822_01
X53416
195464
FLNA
cell_signaling, metastasis
0.9573941
1.004
524
cell_motility_h
Any process involved in the controlled movement of a cell.
H009065_01
Info
Muskelin 1, intracellular mediator containing kelch motifs
H009065_01
NM_013255
288791
MKLN1

0.9931275
1.001
525
ca_nf_at_signalling_h
GEArray
H001935_01
Info
Glyceraldehyde-3-phosphate dehydrogenase
H001935_01
U34995
169476
GAPD

0.0001082
1.485
526
ca_nf_at_signalling_h
GEArray
H001032_01
Info
Cytotoxic T-lymphocyte-associated protein 4
H001032_01
L15006
247824
CTLA4
The Co-Stimulatory Signal During T-cell Activation, immunology
0.0001134
0.56
527
ca_nf_at_signalling_h
GEArray
H003672_01
Info
FOS-like antigen-1
H003672_01
X16707
283565
FOSL1
Bone Remodelling, tsonc
0.0019097
0.779
528
ca_nf_at_signalling_h
GEArray
H002406_01
Info
Jun B proto-oncogene
H002406_01
X51345
198951
JUNB
GATA3 participate in activating the Th2 cytokine genes expression, tsonc
0.0021761
1.408
529
ca_nf_at_signalling_h
GEArray
H000570_01
Info
CREB binding protein (Rubinstein-Taybi syndrome)
H000570_01
U47741
23598
CREBBP
gene_regulation, transcription
0.0048718
1.469
530
ca_nf_at_signalling_h
GEArray
H008667_01
Info
Calcineurin binding protein 1
H008667_01
NM_012295
7840
KIAA0330
Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Role of MEF2D in T-cell Apoptosis
0.0071054
1.322
531
ca_nf_at_signalling_h
GEArray
H002895_01
Info
Mitogen-activated protein kinase 14
H002895_01
L35263
79107
MAPK14
BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAPKinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm ...
0.0086925
1.429
532
ca_nf_at_signalling_h
GEArray
H002944_01
Info
Interleukin 8
H002944_01
M17017
624
IL8
Adhesion and Diapedesis of Granulocytes, Adhesion and Diapedesis of Lymphocytes, Cells and Molecules involved in local acute inflammatory response, Cytokine Network, Cytokines and Inflammatory Response, Free Radical Induced Apoptosis, IL 17 Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Proepithelin Conversion to Epithelin and Wound Repair Control, Regulation of hematopoiesis by cytokines, immunology
0.0100881
0.681
533
ca_nf_at_signalling_h
GEArray
H002831_01
Info
Fc fragment of IgG, low affinity IIIb, receptor for (CD16)
H002831_01
J04162
176663
FCGR3B
immunology
0.0108963
1.803
534
ca_nf_at_signalling_h
GEArray
H003493_01
Info
MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B)
H003493_01
X63380
78881
MEF2B

0.0145042
1.328
535
ca_nf_at_signalling_h
GEArray
H015723_01
Info
Fc fragment of IgG, low affinity IIIa, receptor for (CD16)
H015723_01
NM_000569
300983
FCGR3A
immunology
0.0160639
1.577
536
ca_nf_at_signalling_h
GEArray
H002997_01
Info
Vascular endothelial growth factor
H002997_01
AF022375
73793
VEGF
Actions of Nitric Oxide in the Heart, Hypoxia-Inducible Factor in the Cardiovascular System, VEGF, Hypoxia, and Angiogenesis, angiogenesis, misc
0.0306231
0.782
537
ca_nf_at_signalling_h
GEArray
H000343_01
Info
Early growth response 3
H000343_01
X63741
74088
EGR3
Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, cell_signaling
0.0317099
0.777
538
ca_nf_at_signalling_h
GEArray
H002149_01
Info
Cyclin-dependent kinase inhibitor 1A (p21, Cip1)
H002149_01
U03106
179665
CDKN1A
ATM Signaling Pathway, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, Effects of calcineurin in Keratinocyte Differentiation, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia and p53 in the Cardiovascular system, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, immunology, tsonc
0.0349766
1.236
539
ca_nf_at_signalling_h
GEArray
H001320_01
Info
GATA-binding protein 4
H001320_01
L34357
243987
GATA4
ALK in cardiac myocytes, Hop Pathway in Cardiac Development, NFAT and Hypertrophy of the heart (Transcription in the broken heart), gene_regulation, misc, transcription
0.0421967
0.782
540
ca_nf_at_signalling_h
GEArray
H003259_01
Info
Sp1 transcription factor
H003259_01
J03133
2021
SP1
Agrin in Postsynaptic Differentiation, Effects of calcineurin in Keratinocyte Differentiation, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, MAPKinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase protein component gene hTert Transcriptional Regulation , Overview of telomerase RNA component gene hTerc Transcriptional Regulation
0.0557417
0.814
541
ca_nf_at_signalling_h
GEArray
H002545_01
Info
CD69 antigen (p60, early T-cell activation antigen)
H002545_01
Z22576
82401
CD69
cell_cycle, cell_signaling, immunology
0.0914627
1.212
542
ca_nf_at_signalling_h
GEArray
H002710_01
Info
Interleukin 10
H002710_01
M57627
193717
IL10
Antigen Dependent B Cell Activation, Cytokine Network, Cytokines and Inflammatory Response, Dendritic cells in regulating TH1 and TH2 Development, IL-10 Anti-inflammatory Signaling Pathway, immunology
0.0986725
0.876
543
ca_nf_at_signalling_h
GEArray
H002287_01
Info
P21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related)
H002287_01
U24152
62402
PAK1
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, FAS signaling pathway ( CD95 ), fMLP induced chemokine gene expression in HMC-1 cells, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Rac 1 cell motility signaling pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, TNFR1 Signaling Pathway
0.1104284
0.815
544
ca_nf_at_signalling_h
GEArray
H000398_01
Info
Protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1
H000398_01
U49070
161362
PIN1
How Progesterone Initiates the Oocyte Maturation
0.1163659
1.163
545
ca_nf_at_signalling_h
GEArray
H001128_01
Info
Fc fragment of IgG, low affinity IIIb, receptor for (CD16)
H001128_01
X16863
176663
FCGR3B
immunology
0.1164721
1.303
546
ca_nf_at_signalling_h
GEArray
H010696_01
Info
NCK adaptor protein 2
H010696_01
AF047487
101695
NCK2

0.1245534
1.19
547
ca_nf_at_signalling_h
GEArray
H003158_01
Info
Mitogen-activated protein kinase 8
H003158_01
L26318
190913
MAPK8
Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAPKinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig ...
0.1287835
1.166
548
ca_nf_at_signalling_h
GEArray
H014546_01
Info
Peptidylprolyl isomerase A (cyclophilin A)
H014546_01
NM_021130
182937
PPIA
IL-2 Receptor Beta Chain in T cell Activation
0.129858
1.176
549
ca_nf_at_signalling_h
GEArray
H012917_01
Info
Homo sapiens clone 25048 mRNA sequence
H012917_01
AF131776
321572


0.1524925
0.87
550
ca_nf_at_signalling_h
GEArray
H003550_01
Info
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
H003550_01
S76638
73090
NFKB2
gene_regulation, immunology, transcription, tsonc
0.1593331
1.165
551
ca_nf_at_signalling_h
GEArray
H000372_01
Info
Early growth response 2 (Krox-20 (Drosophila) homolog)
H000372_01
NM_000399
1395
EGR2
Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, immunology
0.1772326
0.796
552
ca_nf_at_signalling_h
GEArray
H003309_01
Info
Mitogen-activated protein kinase kinase 7
H003309_01
AF013589
110299
MAP2K7
Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAPKinase Signaling Pathway
0.3044184
1.088
553
ca_nf_at_signalling_h
GEArray
H001979_01
Info
Protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta)
H001979_01
M29551
151531
PPP3CB
cell_cycle, cell_signaling
0.3386238
0.898
554
ca_nf_at_signalling_h
GEArray
H000650_01
Info
Glycogen synthase kinase 3 beta
H000650_01
L33801
78802
GSK3B
ALK in cardiac myocytes, Cell Cycle: G1/S Check Point , Deregulation of CDK5 in Alzheimers Disease, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Presenilin action in Notch and Wnt signaling, Regulation of eIF2, Segmentation Clock, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Sonic Hedgehog (Shh) Pathway, WNT Signaling Pathway, Phosphatidylinositol signaling system
0.353328
1.118
555
ca_nf_at_signalling_h
GEArray
H001957_01
Info
Interleukin 1, beta
H001957_01
M15330
126256
IL1B
IL 5 Signaling Pathway, Msp/Ron Receptor Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, immunology
0.4390274
1.089
556
ca_nf_at_signalling_h
GEArray
H003578_01
Info
Protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma)
H003578_01
S46622
75206
PPP3CC

0.5197011
0.934
557
ca_nf_at_signalling_h
GEArray
H002104_01
Info
Nucleoporin 214kD (CAIN)
H002104_01
D14689
170285
NUP214

0.5384146
1.074
558
ca_nf_at_signalling_h
GEArray
H001952_01
Info
Ribosomal protein L13a
H001952_01
X56932
119122
RPL13A

0.565051
1.059
559
ca_nf_at_signalling_h
GEArray
H003650_01
Info
Interleukin 2 receptor, alpha
H003650_01
X01057
1724
IL2RA
IL 2 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Role of Tob in T-cell activation, Th1/Th2 Differentiation, immunology
0.5932248
1.054
560
ca_nf_at_signalling_h
GEArray
H007966_01
Info
FK506-binding protein 1B (12.6 kD)
H007966_01
D38037
77643
FKBP1B

0.6042574
0.956
561
ca_nf_at_signalling_h
GEArray
H012106_01
Info
Src-like-adapter
H012106_01
D89077
75367
SLA

0.6044071
0.939
562
ca_nf_at_signalling_h
GEArray
H002812_01
Info
Protein tyrosine phosphatase, receptor type, C
H002812_01
Y00062
170121
PTPRC
Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, B Lymphocyte Cell Surface Molecules, Lck and Fyn tyrosine kinases in initiation of TCR Activation, T Cytotoxic Cell Surface Molecules, T Helper Cell Surface Molecules, cell_cycle, cell_signaling, immunology
0.6066202
1.093
563
ca_nf_at_signalling_h
GEArray
H006762_01
Info
Alu-binding protein with zinc finger domain
H006762_01
U82613
289104
ABP/ZF

0.6091962
0.938
564
ca_nf_at_signalling_h
GEArray
H002045_01
Info
Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
H002045_01
U80917
96149
NFATC1
BCR Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Effects of calcineurin in Keratinocyte Differentiation, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Role of MEF2D in T-cell Apoptosis, Signaling Pathway from G-Protein Families, T Cell Receptor Signaling Pathway, immunology
0.623508
1.051
565
ca_nf_at_signalling_h
GEArray
H003538_01
Info
Actin, beta
H003538_01
NM_001101
288061
ACTB
Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes
0.6253266
0.956
566
ca_nf_at_signalling_h
GEArray
H000983_01
Info
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
H000983_01
X06948
897
FCER1A
Fc Epsilon Receptor I Signaling in Mast Cells, immunology
0.6468177
0.954
567
ca_nf_at_signalling_h
GEArray
H002570_01
Info
Interleukin 2
H002570_01
S82692
89679
IL2
Antigen Dependent B Cell Activation, Cytokine Network, Cytokines and Inflammatory Response, IL 18 Signaling Pathway, IL 2 signaling pathway, OX40 Signaling Pathway, Regulation of hematopoiesis by cytokines, Role of Tob in T-cell activation, Selective expression of chemokine receptors during T-cell polarization, Th1/Th2 Differentiation, The 4-1BB-dependent immune response, The Co-Stimulatory Signal During T-cell Activation, immunology
0.6483346
1.043
568
ca_nf_at_signalling_h
GEArray
H003110_01
Info
Interleukin 6 (interferon, beta 2)
H003110_01
X04430
93913
IL6
Cells and Molecules involved in local acute inflammatory response, Cytokine Network, Cytokines and Inflammatory Response, Erythrocyte Differentiation Pathway, IL 17 Signaling Pathway, IL 5 Signaling Pathway, IL 6 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, Low-density lipoprotein (LDL) pathway during atherogenesis, Regulation of hematopoiesis by cytokines, Role of ERBB2 in Signal Transduction and Oncology, Signal transduction through IL1R, immunology
0.680804
1.036
569
ca_nf_at_signalling_h
GEArray
H001974_01
Info
BCL2-antagonist of cell death
H001974_01
U66879
76366
BAD
AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phosphoinositides and their downstream targets., Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Trefoil Factors Initiate Mucosal Healing, apoptosis, development
0.6985187
0.954
570
ca_nf_at_signalling_h
GEArray
H003153_01
Info
Interleukin 3 (colony-stimulating factor, multiple)
H003153_01
M20137
694
IL3
Cytokine Network, Cytokines and Inflammatory Response, Dendritic cells in regulating TH1 and TH2 Development, Erythrocyte Differentiation Pathway, IL 17 Signaling Pathway, IL 3 signaling pathway, Regulation of BAD phosphorylation, Regulation of hematopoiesis by cytokines, The Role of Eosinophils in the Chemokine Network of Allergy, immunology
0.7001094
1.037
571
ca_nf_at_signalling_h
GEArray
H002470_01
Info
Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
H002470_01
L41067
172674
NFATC3
immunology
0.7190859
0.97
572
ca_nf_at_signalling_h
GEArray
H003043_01
Info
Tumor necrosis factor (ligand) superfamily, member 5 (hyper-IgM syndrome)
H003043_01
X68550
652
TNFSF5
angiogenesis, cell_cycle, cell_signaling, immunology, metastasis
0.7231202
1.028
573
ca_nf_at_signalling_h
GEArray
H001267_01
Info
CD3Z antigen, zeta polypeptide (TiT3 complex)
H001267_01
NM_000734
97087
CD3Z
immunology
0.8300402
1.024
574
ca_nf_at_signalling_h
GEArray
H011554_01
Info
Vav 3 oncogene
H011554_01
NM_006113
267659
VAV3

0.8411784
1.028
575
ca_nf_at_signalling_h
GEArray
H012662_01
Info
Homo sapiens cDNA FLJ10205 fis, clone HEMBA1004954
H012662_01
AK001067
6226


0.8484663
1.017
576
ca_nf_at_signalling_h
GEArray
H011889_01
Info
Glucocorticoid receptor DNA binding factor 1
H011889_01
M73077
102548
GRLF1
Perou's- Intrinsic- Breast-Cancer-Genes
0.876973
0.984
577
ca_nf_at_signalling_h
GEArray
H012455_01
Info
KIAA1291 protein
H012455_01
AB033117
9805
KIAA1291

0.9257104
1.011
578
ca_nf_at_signalling_h
GEArray
H003151_01
Info
E1A binding protein p300
H003151_01
U01877
25272
EP300
Acetylation and Deacetylation of RelA in The Nucleus, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Control of Gene Expression by Vitamin D Receptor, Hypoxia and p53 in the Cardiovascular system, Hypoxia-Inducible Factor in the Cardiovascular System, IL-7 Signal Transduction, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Melanocyte Development and Pigmentation Pathway, Multi-step Regulation of Transcription by Pitx2, NFkB activation by Nontypeable Hemophilus influenzae, Pelp1 Modulation of Estrogen Receptor Activity, Role of ERBB2 in Signal Transduction and Oncology, Role of MEF2D in T-cell Apoptosis, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, TGF beta signaling pathway, Transcription Regulation by Methyltransferase of CARM1, gene_regulation, transcription
0.9607239
1.004
579
ca_nf_at_signalling_h
GEArray
H000579_01
Info
Calmodulin 2 (phosphorylase kinase, delta)
H000579_01
D45887
182278
CALM2

0.9689776
1.004
580
ca_nf_at_signalling_h
GEArray
H002963_01
Info
V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptid
H002963_01
L19067
75569
RELA
Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc
0.9724165
1.003
581
ca_nf_at_signalling_h
GEArray
H000247_01
Info
Sp3 transcription factor
H000247_01
X68560
44450
SP3
Effects of calcineurin in Keratinocyte Differentiation, Overview of telomerase protein component gene hTert Transcriptional Regulation , Overview of telomerase RNA component gene hTerc Transcriptional Regulation
0.985621
0.998
582
ca_nf_at_signalling_h
GEArray
H014820_01
Info
Mitogen-activated protein kinase 9
H014820_01
NM_002752
246857
MAPK9
MAPKinase Signaling Pathway, Phosphatidylinositol signaling system
0.9883614
0.998
583
nfatPathway_h
BioCarta
H000570_01
Info
CREB binding protein (Rubinstein-Taybi syndrome)
H000570_01
U47741
23598
CREBBP
gene_regulation, transcription
0.0048718
1.469
584
nfatPathway_h
BioCarta
H003415_01
Info
Protein kinase, cAMP-dependent, catalytic, beta
H003415_01
M34181
87773
PRKACB
Perou's- Intrinsic- Breast-Cancer-Genes, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction
0.0048904
0.647
585
nfatPathway_h
BioCarta
H002893_01
Info
V-raf-1 murine leukemia viral oncogene homolog 1
H002893_01
X03484
85181
RAF1
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw ...
0.0062484
1.596
586
nfatPathway_h
BioCarta
H003006_01
Info
Serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 8
H003006_01
K02215
3697
SERPINA8
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Angiotensin-converting enzyme 2 regulates heart function, Bioactive Peptide Induced Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, immunology
0.0063778
1.296
587
nfatPathway_h
BioCarta
H002895_01
Info
Mitogen-activated protein kinase 14
H002895_01
L35263
79107
MAPK14
BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAPKinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm ...
0.0086925
1.429
588
nfatPathway_h
BioCarta
H010817_01
Info
Heart and neural crest derivatives expressed 2
H010817_01
AF087940
36029
HAND2
NFAT and Hypertrophy of the heart (Transcription in the broken heart)
0.0143304
1.266
589
nfatPathway_h
BioCarta
H003305_01
Info
Ribosomal protein S6 kinase, 70kD, polypeptide 1
H003305_01
M60724
86858
RPS6KB1
CTCF: First Multivalent Nuclear Factor, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, MAPKinase Signaling Pathway, mTOR Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Rac 1 cell motility signaling pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction
0.0214523
1.448
590
nfatPathway_h
BioCarta
H002145_01
Info
FK506-binding protein 1A (12kD)
H002145_01
M34539
752
FKBP1A
mTOR Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart)
0.0298997
1.239
591
nfatPathway_h
BioCarta
H001320_01
Info
GATA-binding protein 4
H001320_01
L34357
243987
GATA4
ALK in cardiac myocytes, Hop Pathway in Cardiac Development, NFAT and Hypertrophy of the heart (Transcription in the broken heart), gene_regulation, misc, transcription
0.0421