Description of the problem:

Number of classes: 2
Number of genes: 12776
Number of genes that passed filtering criteria: 8324
Type of test used: SAM - Significance analysis of Microarray
Column of the Experiment Descriptors sheet that defines class variable : GROUP

Genes which discriminate among classes:

Table 1
There are 166 genes significant by SAM
The median false discovery rate among the 166 significant genes is 0.08539 .
The delta value used to identify the significant genes is 0.59305 .
The fudge factor for standard deviation is computed as 0.03459 .

Note: For the latest annotations please query the Qiagen website using the Oligo ID number.

	Geometric mean of ratios ( Disease / Normal )	Qiagen oligo ID	Description	GB acc	UG cluster	Gene symbol
1	1.553	H002655_01	Collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant and recessive)	L02870	1640	COL7A1
2	1.453	H007688_01	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	AF109735	195471	PFKFB3
3	1.757	H002994_01	Collagen, type XVIII, alpha 1	AF018081	78409	COL18A1
4	1.689	H016341_01	Platelet derived growth factor C	NM_016205	43080	PDGFC
5	1.422	H006183_01	Metallothionein 1X	X65607	278462	MT1X
6	1.251	H011854_01	Heterogeneous nuclear ribonucleoprotein C (C1/C2)	M16342	182447	HNRPC
7	1.352	H000498_01	Desmoplakin (DPI, DPII)	AL031058	74316	DSP
8	1.249	H003776_01	Aldehyde dehydrogenase 2 family (mitochondrial)	X05409	195432	ALDH2
9	1.436	H012791_01	Metallothionein 1A (functional)	K01383	203967	MT1A
10	1.314	H003383_01	Ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	Z82188	173466	RAC2
11	1.66	H015187_01	Homo sapiens clone N97 immunoglobulin heavy chain variable region mRNA, partial cds	AF103295	283882
12	1.483	H008423_01	EH-domain containing 3	NM_014600	87125	EHD3
13	1.333	H007009_01	Fibroblast growth factor receptor-like 1	AK000530	193326	FGFRL1
14	1.23	H000238_01	KRAB-associated protein 1	X97548	228059	TIF1B
15	1.386	H011703_01	Hypothetical protein FLJ20364	AK000371	32471	FLJ20364
16	1.292	H014948_01	Phosphatidylglycerophosphate Synthase	NM_024419	278682	PGS1
17	1.375	H006492_01	Homo sapiens CD44 isoform RC (CD44) mRNA, complete cds	AF098641	306278
18	1.374	H012664_01	metallothionein 1B (functional)	M13485	211924	MT1B
19	1.292	H006579_01	Hypothetical protein FLJ10292	AK001154	104650	FLJ10292
20	1.427	H008064_01	KIAA0008 gene product	D13633	77695	KIAA0008
21	1.255	H012398_01	KIAA1118 protein	AB029041	209646	KIAA1118
22	1.451	H003725_01	Cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple)	AC003107	1584	COMP
23	1.211	H011172_01	Heat shock protein 75	NM_016292	182366	TRAP1
24	1.243	H009594_01	Neuropathy target esterase	AJ004832	5038	NTE
25	1.445	H008685_01	Metallothionein 2A	V00594	118786	MT2A
26	1.279	H007583_01	Kinesin family member 4A	AF071592	279766	KIF4A
27	1.367	H013251_01	KIAA1329 protein	AB037750	21061	KIAA1329
28	1.189	H015295_01	Homo sapiens HSPC337 mRNA, partial cds	AF161451	284295
29	1.5	H011653_01	Vanilloid receptor-like protein	NM_016113	300686	VRL
30	1.405	H012717_01	Metallothionein 1F (functional)	M10943	203936	MT1F
31	1.193	H003987_01	PRO0659 protein	NM_014138	6451	PRO0659
32	1.415	H009923_01	Vanilloid receptor-like protein 1	NM_015930	279746	VRL-1
33	1.313	H016122_01	TMTSP for transmembrane molecule with thrombospondin module	NM_018676	325667	LOC55901
34	1.244	H012710_01	Hepatitis delta antigen-interacting protein A	U63825	66713	DIPA
35	0.621	H003528_01	Decay accelerating factor for complement (CD55, Cromer blood group system)	M30142	1369	DAF
36	0.548	H003827_01	Serum/glucocorticoid regulated kinase	AJ000512	296323	SGK
37	0.548	H016371_01	Hypothetical protein FLJ21212	NM_024642	47099	FLJ21212
38	0.584	H009347_01	Neuronal cell adhesion molecule	AB002341	7912	NRCAM
39	0.465	H001509_01	Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)	D17793	78183	AKR1C3
40	0.517	H003858_01	Aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-a	U05598	201967	AKR1C2
41	0.62	H010655_01	Hypothetical protein FLJ20546	AK000953	279896	FLJ20546
42	0.811	H005438_01	Homo sapiens mRNA; cDNA DKFZp434B1620 (from clone DKFZp434B1620)	AL137548	43112
43	0.728	H004078_01	Heme-binding protein	NM_015987	108675	HEBP
44	0.708	H002860_01	Inositol polyphosphate-1-phosphatase	L08488	32309	INPP1
45	0.768	H002574_01	Alcohol dehydrogenase 5 (class III), chi polypeptide	M81118	78989	ADH5
46	0.751	H004767_01	Tetraspan 3	AK001326	100090	TSPAN-3
47	0.629	H010640_01	Homo sapiens mRNA; cDNA DKFZp434B1272 (from clone DKFZp434B1272); partial cds	AL162032	158258
48	0.689	H000959_01	Glycophorin C (Gerbich blood group)	NM_002101	81994	GYPC
49	0.721	H003965_01	Cellular repressor of E1A-stimulated genes	AF084523	5710	CREG
50	0.724	H002462_01	Receptor tyrosine kinase-like orphan receptor 1	M97675	274243	ROR1
51	0.664	H007733_01	Retinal short-chain dehydrogenase/reductase retSDR3	NM_016246	18788	LOC51171
52	0.771	H016494_01	Hypothetical protein FLJ12436	NM_024661	69485	FLJ12436
53	0.742	H008089_01	KIAA0469 gene product	AB007938	7764	KIAA0469
54	0.631	H007034_01	Histamine N-methyltransferase	U44111	81182	HNMT
55	0.706	H000410_01	A kinase (PRKA) anchor protein (gravin) 12	U81607	788	AKAP12
56	0.702	H001356_01	KIAA0537 gene product	AB011109	200598	KIAA0537
57	0.538	H001341_01	Platelet-derived growth factor receptor-like	D37965	170040	PDGFRL
58	0.815	H002021_01	V-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein G	AF059195	252229	MAFG
59	0.592	H010453_01	3-alpha hydroxysteroid dehydrogenase type IIb	NM_016253	279801	LOC51708
60	0.685	H005634_01	Solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3	NM_014585	5944	SLC11A3
61	0.68	H008745_01	Acid sphingomyelinase-like phosphodiesterase	AK000184	42945	ASM3A
62	0.704	H003219_01	Glutathione S-transferase M3 (brain)	AF043105	2006	GSTM3
63	0.773	H003951_01	Predicted osteoblast protein	D87120	29882	GS3786
64	0.735	H001047_01	Nidogen 2	AB009799	82733	NID2
65	0.792	H002382_01	Limbic system-associated membrane protein	U41901	26479	LSAMP
66	0.623	H016583_01	1,2-alpha-mannosidase IC	NM_020379	8910	HMIC
67	0.742	H011191_01	Lipin 2	D87436	166318	LPIN2
68	0.803	H002185_01	Niemann-Pick disease, type C1	AF002020	76918	NPC1
69	0.775	H000509_01	Neural precursor cell expressed, developmentally down-regulated 4	D42055	1565	NEDD4
70	0.786	H007419_01	Progesterone membrane binding protein	AJ002030	9071	PMBP
71	0.774	H002121_01	Paraoxonase 2	AF001601	169857	PON2
72	0.805	H008087_01	HSPC019 protein	NM_014028	163724	HSPC019
73	0.696	H002393_01	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	AB000220	171921	SEMA3C
74	0.785	H014975_01	Homo sapiens mRNA; cDNA DKFZp564N1272 (from clone DKFZp564N1272); complete cds	AF087847	282654
75	0.614	H001215_01	Pentaxin-related gene, rapidly induced by IL-1 beta	M31166	2050	PTX3
76	0.756	H002423_01	Vascular endothelial growth factor B	U43368	78781	VEGFB
77	0.768	H010087_01	Destrin (actin depolymerizing factor)	S65738	82306	ADF
78	0.742	H000025_01	Neutral sphingomyelinase (N-SMase) activation associated factor	X96586	78687	NSMAF
79	0.744	H005560_01	WAS protein family, member 1	D87459	75850	WASF1
80	0.786	H014051_01	Very long-chain acyl-CoA synthetase homolog 2	NM_012254	111401	VLCS-H2
81	0.644	H004741_01	Fibroblast growth factor 13	AF100143	6540	FGF13
82	0.764	H001605_01	Annexin A4	NM_001153	77840	ANXA4
83	0.71	H016019_01	Duodenal cytochrome b	AL136693	31297	FLJ23462
84	0.804	H001346_01	Inositol(myo)-1(or 4)-monophosphatase 2	NM_014214	5753	IMPA2
85	0.635	H010918_01	WNT1 inducible signaling pathway protein 2	AF100780	194679	WISP2
86	0.791	H001101_01	CD164 antigen, sialomucin	D14043	43910	CD164
87	0.787	H004431_01	Rag C protein	AF131773	110950	GTR2
88	0.792	H012626_01	Beta-2-microglobulin	AB021288	75415	B2M
89	0.805	H002819_01	Protective protein for beta-galactosidase (galactosialidosis)	AL008726	118126	PPGB
90	0.684	H002497_01	Complement component 1, r subcomponent	M14058	1279	C1R
91	0.691	H006676_01	Lung type-I cell membrane-associated glycoprotein	AF030428	135150	T1A-2
92	0.653	H012777_01	KIAA1199 protein	AB033025	50081	KIAA1199
93	0.721	H003789_01	Colony stimulating factor 1 (macrophage)	M37435	173894	CSF1
94	0.849	H008439_01	SCO (cytochrome oxidase deficient, yeast) homolog 1	AF026852	14511	SCO1
95	0.774	H008994_01	Solute carrier family 31 (copper transporters), member 2	U83461	24030	SLC31A2
96	0.774	H010497_01	Interferon induced transmembrane protein 3 (1-8U)	X57352	182241	IFITM3
97	0.762	H011175_01	Opsin 3 (encephalopsin)	NM_014322	279926	OPN3
98	0.701	H011671_01	Short-chain dehydrogenase/reductase 1	AF061741	17144	SDR1
99	0.767	H002804_01	Prion protein (p27-30) (Creutzfeld-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal fami	U29185	74621	PRNP
100	0.792	H002258_01	UDP-glucose pyrophosphorylase 2	U27460	77837	UGP2
101	0.659	H001491_01	Cyclin T2	AF048731	155478	CCNT2
102	0.762	H002746_01	TNF receptor-associated factor 5	AB000509	29736	TRAF5
103	0.766	H013070_01	Sarcoglycan, epsilon	AJ000534	110708	SGCE
104	0.761	H001062_01	N-acylsphingosine amidohydrolase (acid ceramidase)	U70063	75811	ASAH
105	0.814	H002694_01	Glutathione peroxidase 4 (phospholipid hydroperoxidase)	X71973	2706	GPX4
106	0.774	H011917_01	Sorting nexin 3	AF034546	12102	SNX3
107	0.754	H006813_01	Homo sapiens cDNA FLJ11309 fis, clone PLACE1010076	AK002171	28005
108	0.821	H002793_01	Antigen identified by monoclonal antibodies 12E7, F21 and O13	M16279	177543	MIC2
109	0.844	H000474_01	Testis-specific kinase 1	D50863	79358	TESK1
110	0.731	H000930_01	Low density lipoprotein receptor (familial hypercholesterolemia)	L00352	213289	LDLR
111	0.802	H009135_01	Electron-transferring-flavoprotein dehydrogenase	S69232	323468	ETFDH
112	0.767	H008544_01	Atrophin-1 interacting protein 1; activin receptor interacting protein 1	AB014605	22599	KIAA0705
113	0.789	H000400_01	Growth arrest-specific 6	L13720	78501	GAS6
114	0.762	H016469_01	MEK partner 1	NM_021970	6361	MP1
115	0.731	H002820_01	Ectodermal-neural cortex (with BTB-like domain)	AF059611	104925	ENC1
116	0.75	H016592_01	Hypothetical protein FLJ12816	NM_022060	9175	FLJ12816
117	0.792	H006873_01	CGI-149 protein	NM_016079	189658	LOC51652
118	0.592	H002066_01	Aldehyde dehydrogenase 1 family, member A1	M31994	76392	ALDH1A1
119	0.689	H013490_01	H.sapiens polyA site DNA	Z24724	4934
120	0.76	H015305_01	Hypothetical protein FLJ22029	NM_024949	285243	FLJ22029
121	0.704	H002566_01	Membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10)	NM_007289	1298	MME
122	0.81	H002169_01	Sortilin-related receptor, L(DLR class) A repeats-containing	NM_003105	278571	SORL1
123	0.88	H003649_01	Protein tyrosine phosphatase, non-receptor type 6	X62055	63489	PTPN6
124	0.744	H011942_01	Activating transcription factor 5	AB021663	9754	ATF5
125	0.806	H007715_01	KIAA1091 protein	AL117448	26797	KIAA1091
126	0.823	H012019_01	Epithelial protein lost in neoplasm beta	NM_016357	10706	EPLIN
127	0.838	H010079_01	Hypothetical protein FLJ10337	AB037858	173484	KIAA1437
128	0.772	H003031_01	Glycoprotein A repetitions predominant	Z24680	151641	GARP
129	0.762	H002785_01	Serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1	X54486	151242	SERPING1
130	0.631	H000082_01	Deiodinase, iodothyronine, type II	NM_013989	154424	DIO2
131	0.755	H007381_01	Hypothetical protein FLJ10044	AK000906	127273	FLJ10044
132	0.699	H014982_01	Tuftelin 1	NM_020127	283009	TUFT1
133	0.813	H003637_01	Protein tyrosine phosphatase, non-receptor type 12	M93425	62	PTPN12
134	0.821	H002684_01	Bone morphogenetic protein 6	NM_001718	285671	BMP6
135	0.847	H001078_01	ATPase, Na+/K+ transporting, beta 3 polypeptide	NM_001679	76941	ATP1B3
136	0.785	H009413_01	KIAA0321 protein	AB002319	8663	KIAA0321
137	0.806	H003439_01	Protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform	M60484	80350	PPP2CB
138	0.811	H011488_01	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5	AL035683	107526	B4GALT5
139	0.631	H002334_01	Cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile)	U03688	154654	CYP1B1
140	0.797	H006973_01	Homo sapiens cDNA FLJ10598 fis, clone NT2RP2004841	AK001460	170873
141	0.737	H008497_01	Amyloid beta (A4) precursor-like protein 2	NM_016160	279518	APLP2
142	0.802	H000517_01	Phorbol-12-myristate-13-acetate-induced protein 1	D90070	96	PMAIP1
143	0.799	H007506_01	Clock (mouse) homolog	AB002332	50722	CLOCK
144	0.831	H002305_01	Accessory proteins BAP31/BAP29	S74039	291904	DXS1357E
145	0.813	H002571_01	Meiotic recombination (S. cerevisiae) 11 homolog B	AF022778	202379	MRE11B
146	0.795	H002782_01	Wee1+ (S. pombe) homolog	X62048	75188	WEE1
147	0.814	H002076_01	Interleukin-1 receptor-associated kinase 1	L76191	182018	IRAK1
148	0.82	H000048_01	PRKC, apoptosis, WT1, regulator	U63809	176090	PAWR
149	0.578	H005801_01	Purkinje cell protein 4	U52969	80296	PCP4
150	0.834	H002311_01	Transcription factor 7-like 2 (T-cell specific, HMG-box)	Y11306	173638	TCF7L2
151	0.774	H008367_01	KIAA0623 gene product	AB014523	151406	KIAA0623
152	0.809	H005443_01	Interferon-related developmental regulator 1	AC005192	7879	IFRD1
153	0.796	H005941_01	Hypothetical protein FLJ20043	AK000050	103853	FLJ20043
154	0.731	H009185_01	KIAA1144 protein	AB032970	22675	KIAA1144
155	0.737	H011708_01	Homo sapiens clone 24405 mRNA sequence	AF070632	23729
156	0.848	H016365_01	Core1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase	NM_020156	46744	C1GALT1
157	0.763	H010122_01	Homo sapiens mRNA; cDNA DKFZp586F1223 (from clone DKFZp586F1223)	AL050204	28540
158	0.71	H002475_01	Pim-1 oncogene	M54915	81170	PIM1
159	0.794	H007334_01	SH3 domain binding glutamic acid-rich protein like	AF042081	14368	SH3BGRL
160	0.817	H000893_01	Major histocompatibility complex, class I, E	X56841	181392	HLA-E
161	0.737	H010951_01	LIM domain only 4	NM_006769	3844	LMO4
162	0.846	H001759_01	Chloride channel 7	AL031600	80768	CLCN7
163	0.845	H001612_01	RAP1, GTP-GDP dissociation stimulator 1	AF237413	7940	RAP1GDS1
164	0.753	H007858_01	Glutaminyl-peptide cyclotransferase (glutaminyl cyclase)	X71125	79033	QPCT
165	0.808	H002897_01	Cathepsin L	X12451	78056	CTSL
166	0.84	H004099_01	Phosphatidic acid phosphatase type 2A	AF014403	41569	PPAP2A