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SUPPLEMENTAL DATA
1. Classification analysis of the transcriptosome of non-lesional cultured dermal fibroblasts from scleroderma patients with early disease. Arthritis Rheum 2005, 52:865-876
- Genes differentially expressed by Significance Analysis of Microarrays (SAM)
- Genes differentially expressed by the random variance t-test
- Class Prediction (nominal gene set)
- Comparative gene ontology analysis
- Cluster analysis of SSc samples
- Biological pathway comparison
- Pathway analysis(Pathway Assist)
2. Clinically discordant scleroderma monozygotic twins show concordance for fibroblast gene expression profiles. Arthritis Rheum, 2005, 52: 3305-3314
3. Signatures of differentially regulated interferon gene expression and vasculotropism in the peripheral blood cells of systemic sclerosis patients. Rheumatology (Oxford), 2006, 45: 694-702
- Genes differentially expressed in SSc PBCs by SAM
- Class comparison with the random variance T-test and conditional false discovery rate with SPLOSH (Large!)
- Cluster analysis of SSc and control peripheral blood samples
- Biological pathways differentially regulated in SSc PBC samples
- Comparative gene ontology (GO) analysis
4. Major
histocompatibility complex (MHC) class II alleles and epitopes which
confer susceptibility or protection in systemic
sclerosis: analyses in 1300 Caucasina, African-American and Hispanic
cases and 1000 controls. Ann
Rheum Dis 2010 69: 822-827
5. Systemic
sclerosis
and
Lupus: Points in an interferon-mediated continuum. Arthritis
Rheum, 2010, 62:589-598
- Supplement 1 - Methods
- Supplement 2 - Functional grouping of transcripts differentially expressed in SLE and SSc compared to controls
- Class comparsion of SLE vs controls
- Class comparison of SSc vs controls
- Class comparison of SLE vs SSc
- Supplement 3 - Modeling of IFN signaling pathways in Ingenuity Pathyway Analysis