Number of investigated GO categories: 1200
                       
GO categories which discriminate among classes:
Table - Sorted by p-value of the LS permutation test.
The first 12 GO categories are significant at the nominal 0.01 level of the LS permutation test or KS permutation test
  GO category GO description Number of genes LS Permutation p-value KS Permutation p-value
1 5581 collagen 18 0.00289 0.01794
2 5201 extracellular matrix structural constituent 35 0.00612 0.02334
3 776 kinetochore 9 0.00655 0.00447
4 6401 RNA catabolism 9 0.00701 0.14152
5 5520 insulin-like growth factor binding 7 0.00806 0.04783
6 4252 serine-type endopeptidase activity 33 0.01633 0.00489
7 8287 protein serine/threonine phosphatase complex 16 0.04178 0.00162
8 4295 trypsin activity 25 0.04551 0.00922
9 43087 regulation of GTPase activity 6 0.05519 0.00484
10 6687 glycosphingolipid metabolism 6 0.20802 0.00758
11 30148 sphingolipid biosynthesis 5 0.218 0.00791
12 6664 glycolipid metabolism 8 0.24384 0.00228
Table Significant GO categories consist of the following genes:
  GO category GO desciption Qiagen Oligo ID Description GB acc UG cluster Gene symbol Geometric mean of ratios in Norm Geometric mean of ratios in SSc Fold difference of Geometric means p-value
1 5581 collagen H001909_01 Collagen, type IV, alpha 2 X05610 75617 COL4A2 0.774 1.455 1.88 0.16588
2 5581 collagen H001981_01 Collagen, type VI, alpha 3 X52022 80988 COL6A3 13.102 14.887 1.14 0.3969
3 5581 collagen H002090_01 Collagen, type XVI, alpha 1 M92642 26208 COL16A1 1.487 0.807 0.54 0.01286
4 5581 collagen H002160_01 Collagen, type V, alpha 2 Y14690 82985 COL5A2 2.909 7.335 2.52 0.02257
5 5581 collagen H002647_01 Collagen, type XV, alpha 1 L25286 83164 COL15A1 2.556 1.679 0.66 0.06883
6 5581 collagen H002655_01 Collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant and recessive) L02870 1640 COL7A1 1.353 1.381 1.02 0.90084
7 5581 collagen H002915_01 Collagen, type VIII, alpha 1 X57527 114599 COL8A1 1.699 4.652 2.74 0.00779
8 5581 collagen H002994_01 Collagen, type XVIII, alpha 1 AF018081 78409 COL18A1 1.233 1.081 0.88 0.55803
9 5581 collagen H003072_01 Collagen, type I, alpha 2 J03464 179573 COL1A2 2.917 9.772 3.35 0.00199
10 5581 collagen H003413_01 Lumican U21128 79914 LUM 5.429 6.831 1.26 0.38015
11 5581 collagen H003504_01 Collagen, type I, alpha 1 Z74615 172928 COL1A1 1.499 1.334 0.89 0.5702
12 5581 collagen H003593_01 Collagen, type VI, alpha 2 AL096746 159263 COL6A2 11.306 8.367 0.74 0.19054
13 5581 collagen H006623_01 Homo sapiens clone HB-2 mRNA sequence AF216077 48376   1.078 1.072 0.99 0.98024
14 5581 collagen H000708_01 Collagen, type XIX, alpha 1 D38163 89457 COL19A1 1.008 1.613 1.60 0.15001
15 5581 collagen H000774_01 Collagen, type VI, alpha 1 X15880 108885 COL6A1 7.419 14.402 1.94 0.01162
16 5581 collagen H012686_01 Collagen, type XIII, alpha 1 NM_005203 211933 COL13A1 3.087 6.268 2.03 0.12493
17 5581 collagen H015060_01 Smooth muscle cell-expressed and macrophage conditioned medium-induced protein smag-64 NM_020351 283100 LOC57086 0.419 0.612 1.46 0.01543
18 5581 collagen H001198_01 Homo sapiens, alpha-1 (VI) collagen M20776 25459   7.041 6.65 0.94 0.79953
19 5201 extracellular matrix structural constituent H001909_01 Collagen, type IV, alpha 2 X05610 75617 COL4A2 0.774 1.455 1.88 0.16588
20 5201 extracellular matrix structural constituent H001981_01 Collagen, type VI, alpha 3 X52022 80988 COL6A3 13.102 14.887 1.14 0.3969
21 5201 extracellular matrix structural constituent H002090_01 Collagen, type XVI, alpha 1 M92642 26208 COL16A1 1.487 0.807 0.54 0.01286
22 5201 extracellular matrix structural constituent H002143_01 Fibrillin 1 (Marfan syndrome) X63556 750 FBN1 8.277 5.989 0.72 0.1062
23 5201 extracellular matrix structural constituent H002160_01 Collagen, type V, alpha 2 Y14690 82985 COL5A2 2.909 7.335 2.52 0.02257
24 5201 extracellular matrix structural constituent H002196_01 Nidogen (enactin) M30269 62041 NID 1.534 1.486 0.97 0.80662
25 5201 extracellular matrix structural constituent H002647_01 Collagen, type XV, alpha 1 L25286 83164 COL15A1 2.556 1.679 0.66 0.06883
26 5201 extracellular matrix structural constituent H002655_01 Collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant and recessive) L02870 1640 COL7A1 1.353 1.381 1.02 0.90084
27 5201 extracellular matrix structural constituent H002915_01 Collagen, type VIII, alpha 1 X57527 114599 COL8A1 1.699 4.652 2.74 0.00779
28 5201 extracellular matrix structural constituent H002994_01 Collagen, type XVIII, alpha 1 AF018081 78409 COL18A1 1.233 1.081 0.88 0.55803
29 5201 extracellular matrix structural constituent H003066_01 Biglycan J04599 821 BGN 3.118 3.278 1.05 0.87448
30 5201 extracellular matrix structural constituent H003072_01 Collagen, type I, alpha 2 J03464 179573 COL1A2 2.917 9.772 3.35 0.00199
31 5201 extracellular matrix structural constituent H003413_01 Lumican U21128 79914 LUM 5.429 6.831 1.26 0.38015
32 5201 extracellular matrix structural constituent H003504_01 Collagen, type I, alpha 1 Z74615 172928 COL1A1 1.499 1.334 0.89 0.5702
33 5201 extracellular matrix structural constituent H003593_01 Collagen, type VI, alpha 2 AL096746 159263 COL6A2 11.306 8.367 0.74 0.19054
34 5201 extracellular matrix structural constituent H004275_01 Elastin microfibril interface located protein AL050138 63348 EMILIN 1.261 1.004 0.80 0.16069
35 5201 extracellular matrix structural constituent H005515_01 EGF-containing fibulin-like extracellular matrix protein 2 AJ132819 6059 EFEMP2 5.651 4.95 0.88 0.56638
36 5201 extracellular matrix structural constituent H006167_01 Mucin 4, tracheobronchial AJ242549 198267 MUC4 1.088 1.118 1.03 0.87749
37 5201 extracellular matrix structural constituent H006182_01 Matrilin 3 AJ224741 278461 MATN3 1.019 0.762 0.75 0.04621
38 5201 extracellular matrix structural constituent H006243_01 Matrilin 4 AJ007581 278489 MATN4 1.13 1.322 1.17 0.55955
39 5201 extracellular matrix structural constituent H006623_01 Homo sapiens clone HB-2 mRNA sequence AF216077 48376   1.078 1.072 0.99 0.98024
40 5201 extracellular matrix structural constituent H000708_01 Collagen, type XIX, alpha 1 D38163 89457 COL19A1 1.008 1.613 1.60 0.15001
41 5201 extracellular matrix structural constituent H000774_01 Collagen, type VI, alpha 1 X15880 108885 COL6A1 7.419 14.402 1.94 0.01162
42 5201 extracellular matrix structural constituent H011464_01 Microfibrillar-associated protein 3 AL049404 28785 MFAP3 1.662 1.851 1.11 0.59568
43 5201 extracellular matrix structural constituent H012686_01 Collagen, type XIII, alpha 1 NM_005203 211933 COL13A1 3.087 6.268 2.03 0.12493
44 5201 extracellular matrix structural constituent H000992_01 Fibulin 2 X82494 198862 FBLN2 19.293 19.864 1.03 0.92471
45 5201 extracellular matrix structural constituent H013067_01 Amelogenin (Y chromosome) M86933 1238 AMELY 1.331 1.265 0.95 0.79442
46 5201 extracellular matrix structural constituent H014507_01 P3ECSL NM_022164 173508 LIECG3 0.929 0.847 0.91 0.51546
47 5201 extracellular matrix structural constituent H015060_01 Smooth muscle cell-expressed and macrophage conditioned medium-induced protein smag-64 NM_020351 283100 LOC57086 0.419 0.612 1.46 0.01543
48 5201 extracellular matrix structural constituent H001146_01 Opticin AJ133790 241413 OPTC 2.525 5.605 2.22 0.06954
49 5201 extracellular matrix structural constituent H001149_01 Microfibrillar-associated protein 2 U19718 83551 MFAP2 3.978 6.902 1.74 0.00148
50 5201 extracellular matrix structural constituent H001198_01 Homo sapiens, alpha-1 (VI) collagen M20776 25459   7.041 6.65 0.94 0.79953
51 5201 extracellular matrix structural constituent H001200_01 Microfibril-associated glycoprotein-2 NM_003480 300946 MAGP2 10.634 11.229 1.06 0.87915
52 5201 extracellular matrix structural constituent H016066_01 Homo sapiens mRNA for MSF-FN70 (FN gene) AJ276395 321592   6.836 13.007 1.90 0.07589
53 5201 extracellular matrix structural constituent H016249_01 Homo sapiens, Similar to laminin, alpha 4, clone MGC:10389, mRNA, complete cds BC004241 327703   1.019 0.689 0.68 0.05838
54 776 kinetochore H002651_01 Presenilin 1 (Alzheimer disease 3) L76517 3260 PSEN1 1.674 1.337 0.80 0.38047
55 776 kinetochore H003796_01 Centromere protein F (350/400kD, mitosin) U30872 77204 CENPF 0.908 1.193 1.31 0.40243
56 776 kinetochore H004455_01 SMT3 (suppressor of mif two 3, yeast) homolog 1 X99584 85119 SMT3H1 1.312 0.851 0.65 0.03052
57 776 kinetochore H000555_01 MAD2 (mitotic arrest deficient, yeast, homolog)-like 1 U65410 79078 MAD2L1 3.691 14.522 3.93 0.00753
58 776 kinetochore H007906_01 Kinesin-like 4 AB017430 119324 KNSL4 0.484 0.313 0.65 0.15055
59 776 kinetochore H009464_01 Centromere protein F (350/400kD, mitosin) NM_016343 77204 CENPF 0.806 0.968 1.20 0.10591
60 776 kinetochore H010859_01 BUB3 (budding uninhibited by benzimidazoles 3, yeast) homolog AF047472 40323 BUB3 0.88 0.571 0.65 0.01436
61 776 kinetochore H014640_01 Kinetochore protein CENP-H NM_022909 200395 CENPH 0.515 0.361 0.70 0.16289
62 776 kinetochore H001444_01 Dynactin 2 (p50) U50733 84153 DCTN2 1.693 2.254 1.33 0.05946
63 6401 RNA catabolism H001873_01 Zinc finger protein homologous to Zfp-36 in mouse M92843 1665 ZFP36 1.293 1.109 0.86 0.47715
64 6401 RNA catabolism H004497_01 KIAA0116 protein D29958 182877 KIAA0116 0.341 0.537 1.57 0.00154
65 6401 RNA catabolism H006056_01 Regulator of nonsense transcripts 1 D86988 12719 RENT1 1.267 1.299 1.03 0.90558
66 6401 RNA catabolism H006885_01 Ribonuclease 6 precursor NM_003730 8297 RNASE6PL 0.712 0.438 0.62 0.03907
67 6401 RNA catabolism H008151_01 Heat shock 70kD protein 1B NM_005346 274402 HSPA1B 1.036 0.533 0.51 0.01103
68 6401 RNA catabolism H008749_01 PRO2047 protein NM_014110 284136 PRO2047 0.948 1.128 1.19 0.35127
69 6401 RNA catabolism H010646_01 Ribonuclease 6 precursor AK001769 8297 RNASE6PL 0.862 0.836 0.97 0.71042
70 6401 RNA catabolism H010958_01 Poly(A)-binding protein, cytoplasmic 4 (inducible form) U75686 169900 PABPC4 1.3 0.758 0.58 0.00593
71 6401 RNA catabolism H011931_01 Protein phosphatase 1, regulatory (inhibitor) subunit 8 U14575 78961 PPP1R8 1.351 0.949 0.70 0.21242
72 5520 insulin-like growth factor binding H002800_01 Connective tissue growth factor X78947 75511 CTGF 3.098 14.225 4.59 0.00073
73 5520 insulin-like growth factor binding H003420_01 Insulin-like growth factor binding protein 6 M62402 274313 IGFBP6 2.297 1.431 0.62 0.06015
74 5520 insulin-like growth factor binding H003735_01 Insulin-like growth factor binding protein 5 AF055033 107169 IGFBP5 1.33 1.69 1.27 0.46462
75 5520 insulin-like growth factor binding H003777_01 Insulin-like growth factor binding protein 2 (36kD) X16302 162 IGFBP2 0.195 0.401 2.06 0.09799
76 5520 insulin-like growth factor binding H000589_01 Cysteine-rich, angiogenic inducer, 61 Y11307 8867 CYR61 5.224 7.438 1.42 0.31927
77 5520 insulin-like growth factor binding H007289_01 Insulin-like growth factor binding protein 7 S75725 119206 IGFBP7 1.036 1.769 1.71 0.20545
78 5520 insulin-like growth factor binding H012536_01 Human insulin-like growth factor binding protein 5 (IGFBP5) mRNA L27560 103391   0.841 1.699 2.02 0.02933
79 4252 serine-type endopeptidase activity H001768_01 Protease, serine, 2 (trypsin 2) M27602 241561 PRSS2 0.224 0.131 0.58 0.23624
80 4252 serine-type endopeptidase activity H001780_01 Protease, serine, 4 (trypsin 4, brain) X72781 58247 PRSS4 0.566 0.794 1.40 0.28828
81 4252 serine-type endopeptidase activity H001785_01 Hepsin (transmembrane protease, serine 1) X07732 823 HPN 0.834 1.882 2.26 0.01749
82 4252 serine-type endopeptidase activity H001797_01 Protease, serine, 1 (trypsin 1) M22612 241395 PRSS1 2.029 2.174 1.07 0.5579
83 4252 serine-type endopeptidase activity H001828_01 Pancreatic elastase IIB M16653 169234 LOC51032 1.085 1.765 1.63 0.12304
84 4252 serine-type endopeptidase activity H001830_01 Transmembrane protease, serine 2 U75329 318545 TMPRSS2 1.334 1.114 0.84 0.54555
85 4252 serine-type endopeptidase activity H001920_01 Coagulation factor VII (serum prothrombin conversion accelerator) M13232 36989 F7 0.98 1.638 1.67 0.05764
86 4252 serine-type endopeptidase activity H001925_01 Granzyme M (lymphocyte met-ase 1) NM_005317 268531 GZMM 0.644 1.061 1.65 0.03318
87 4252 serine-type endopeptidase activity H002030_01 Tryptase, alpha M30038 278528 TPS1 1.225 0.924 0.75 0.07983
88 4252 serine-type endopeptidase activity H002188_01 Lipoprotein, Lp(a) X06290 119520 LPA 0.655 1.066 1.63 0.06567
89 4252 serine-type endopeptidase activity H002460_01 Plasminogen activator, tissue M15518 274404 PLAT 0.852 0.76 0.89 0.58882
90 4252 serine-type endopeptidase activity H002509_01 D component of complement (adipsin) M84526 155597 DF 1.468 0.957 0.65 0.02192
91 4252 serine-type endopeptidase activity H002528_01 Granzyme K (serine protease, granzyme 3; tryptase II) U26174 3066 GZMK 0.919 1.163 1.27 0.33764
92 4252 serine-type endopeptidase activity H002553_01 Serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), M14083 82085 SERPINE1 0.841 1.12 1.33 0.01068
93 4252 serine-type endopeptidase activity H002605_01 Mannan-binding lectin serine protease 2 X98400 119983 MASP2 0.608 0.51 0.84 0.42079
94 4252 serine-type endopeptidase activity H002927_01 Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2 Y00630 75716 SERPINB2 0.558 0.682 1.22 0.60481
95 4252 serine-type endopeptidase activity H003011_01 Complement component 1, s subcomponent J04080 169756 C1S 16.305 18.098 1.11 0.78389
96 4252 serine-type endopeptidase activity H003053_01 Kallikrein 11 AB012917 57771 KLK11 0.416 0.554 1.33 0.27282
97 4252 serine-type endopeptidase activity H003287_01 Kallikrein 5 NM_012427 50915 KLK5 1.005 1.643 1.63 0.08562
98 4252 serine-type endopeptidase activity H003337_01 B-factor, properdin L15702 69771 BF 0.614 0.963 1.57 0.11883
99 4252 serine-type endopeptidase activity H003368_01 Kallikrein 1, renal/pancreas/salivary M25629 123107 KLK1 0.86 0.863 1.00 0.9892
100 4252 serine-type endopeptidase activity H003754_01 ClpP (caseinolytic protease, ATP-dependent, proteolytic subunit, E. coli) homolog Z50853 74362 CLPP 1.219 0.922 0.76 0.0866
101 4252 serine-type endopeptidase activity H003865_01 Lactotransferrin X53961 105938 LTF 0.65 0.466 0.72 0.17982
102 4252 serine-type endopeptidase activity H003877_01 Paired basic amino acid cleaving enzyme (furin, membrane associated receptor protein) X17094 59242 PACE 1.199 0.917 0.76 0.21199
103 4252 serine-type endopeptidase activity H004648_01 Tryptase gamma 1 NM_012467 278275 TPSG1 0.816 1.161 1.42 0.06632
104 4252 serine-type endopeptidase activity H000491_01 Proprotein convertase subtilisin/kexin type 7 U33849 32978 PCSK7 1.697 1.141 0.67 0.01513
105 4252 serine-type endopeptidase activity H005647_01 Membrane-bound transcription factor protease, site 1 D42053 75890 MBTPS1 1.72 2.046 1.19 0.61228
106 4252 serine-type endopeptidase activity H006381_01 Protease, serine, 23 AF015287 325820 SPUVE 1.423 2.047 1.44 0.18652
107 4252 serine-type endopeptidase activity H007042_01 Complement C1r-like proteinase precursor, AF178985 98571 LOC51279 1.077 0.984 0.91 0.48438
108 4252 serine-type endopeptidase activity H013087_01 Rhomboid (veinlet, Drosophila)-like Y17108 137572 RHBDL 0.891 0.853 0.96 0.86092
109 4252 serine-type endopeptidase activity H015697_01 Transmembrane protease, serine 3 NM_024022 298241 TMPRSS3 0.984 0.702 0.71 0.11262
110 4252 serine-type endopeptidase activity H001308_01 Proteinase 3 (serine proteinase, neutrophil, Wegener granulomatosis autoantigen) X55668 928 PRTN3 0.819 1.211 1.48 0.216
111 4252 serine-type endopeptidase activity H001448_01 HtrA-like serine protease NM_013247 115721 OMI 1.18 1.41 1.19 0.18541
112 8287 protein serine/threonine phosphatase complex H002974_01 KIAA0015 gene product D13640 278441 KIAA0015 1.756 1.368 0.78 0.23236
113 8287 protein serine/threonine phosphatase complex H003020_01 Protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform S87759 57764 PPM1A 2.483 4.223 1.70 0.1493
114 8287 protein serine/threonine phosphatase complex H003074_01 Protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform M64929 179574 PPP2R2A 0.9 0.594 0.66 0.17157
115 8287 protein serine/threonine phosphatase complex H003642_01 Protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform Y13936 17883 PPM1G 0.759 0.902 1.19 0.29144
116 8287 protein serine/threonine phosphatase complex H000413_01 Protein phosphatase 2, regulatory subunit B (B56), epsilon isoform L76703 173328 PPP2R5E 1.03 0.825 0.80 0.24141
117 8287 protein serine/threonine phosphatase complex H000464_01 Protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform M65254 108705 PPP2R1B 1.156 1.334 1.15 0.47031
118 8287 protein serine/threonine phosphatase complex H005412_01 Protein phosphatase 2, regulatory subunit B (B56), delta isoform L76702 118244 PPP2R5D 1.372 1.085 0.79 0.21517
119 8287 protein serine/threonine phosphatase complex H006260_01 Protein phosphatase 2A 48 kDa regulatory subunit NM_013239 124942 PR48 0.8 0.978 1.22 0.40781
120 8287 protein serine/threonine phosphatase complex H000599_01 Protein phosphatase 1D magnesium-dependent, delta isoform U78305 100980 PPM1D 1.16 0.724 0.62 0.15614
121 8287 protein serine/threonine phosphatase complex H000617_01 Protein phosphatase 2, regulatory subunit B (B56), beta isoform L42374 75199 PPP2R5B 1.334 2.159 1.62 0.15054
122 8287 protein serine/threonine phosphatase complex H000644_01 Protein phosphatase 2, regulatory subunit B (B56), alpha isoform L42373 155079 PPP2R5A 0.581 0.802 1.38 0.12309
123 8287 protein serine/threonine phosphatase complex H008583_01 Homo sapiens mRNA; cDNA DKFZp761E0711 (from clone DKFZp761E0711) AL157449 110095   1.677 1.242 0.74 0.1797
124 8287 protein serine/threonine phosphatase complex H010455_01 KIAA1348 protein AB037769 232696 KIAA1348 1.084 0.986 0.91 0.23445
125 8287 protein serine/threonine phosphatase complex H014726_01 Pyruvate dehydrogenase phosphatase NM_018444 22265 PDP 1.946 1.113 0.57 0.00658
126 8287 protein serine/threonine phosphatase complex H001703_01 Protein phosphatase 2 (formerly 2A), regulatory subunit B'' (PR 72), alpha isoform and (PR 130), bet L07590 28219 PPP2R3 1.489 1.204 0.81 0.40966
127 8287 protein serine/threonine phosphatase complex H001704_01 Protein phosphatase 2, regulatory subunit B (B56), gamma isoform U37352 171734 PPP2R5C 1.056 1.61 1.52 0.01011
128 4295 trypsin activity H001768_01 Protease, serine, 2 (trypsin 2) M27602 241561 PRSS2 0.224 0.131 0.58 0.23624
129 4295 trypsin activity H001780_01 Protease, serine, 4 (trypsin 4, brain) X72781 58247 PRSS4 0.566 0.794 1.40 0.28828
130 4295 trypsin activity H001785_01 Hepsin (transmembrane protease, serine 1) X07732 823 HPN 0.834 1.882 2.26 0.01749
131 4295 trypsin activity H001797_01 Protease, serine, 1 (trypsin 1) M22612 241395 PRSS1 2.029 2.174 1.07 0.5579
132 4295 trypsin activity H001828_01 Pancreatic elastase IIB M16653 169234 LOC51032 1.085 1.765 1.63 0.12304
133 4295 trypsin activity H001830_01 Transmembrane protease, serine 2 U75329 318545 TMPRSS2 1.334 1.114 0.84 0.54555
134 4295 trypsin activity H001920_01 Coagulation factor VII (serum prothrombin conversion accelerator) M13232 36989 F7 0.98 1.638 1.67 0.05764
135 4295 trypsin activity H001925_01 Granzyme M (lymphocyte met-ase 1) NM_005317 268531 GZMM 0.644 1.061 1.65 0.03318
136 4295 trypsin activity H002030_01 Tryptase, alpha M30038 278528 TPS1 1.225 0.924 0.75 0.07983
137 4295 trypsin activity H002188_01 Lipoprotein, Lp(a) X06290 119520 LPA 0.655 1.066 1.63 0.06567
138 4295 trypsin activity H002460_01 Plasminogen activator, tissue M15518 274404 PLAT 0.852 0.76 0.89 0.58882
139 4295 trypsin activity H002509_01 D component of complement (adipsin) M84526 155597 DF 1.468 0.957 0.65 0.02192
140 4295 trypsin activity H002528_01 Granzyme K (serine protease, granzyme 3; tryptase II) U26174 3066 GZMK 0.919 1.163 1.27 0.33764
141 4295 trypsin activity H002605_01 Mannan-binding lectin serine protease 2 X98400 119983 MASP2 0.608 0.51 0.84 0.42079
142 4295 trypsin activity H003011_01 Complement component 1, s subcomponent J04080 169756 C1S 16.305 18.098 1.11 0.78389
143 4295 trypsin activity H003053_01 Kallikrein 11 AB012917 57771 KLK11 0.416 0.554 1.33 0.27282
144 4295 trypsin activity H003287_01 Kallikrein 5 NM_012427 50915 KLK5 1.005 1.643 1.63 0.08562
145 4295 trypsin activity H003337_01 B-factor, properdin L15702 69771 BF 0.614 0.963 1.57 0.11883
146 4295 trypsin activity H003368_01 Kallikrein 1, renal/pancreas/salivary M25629 123107 KLK1 0.86 0.863 1.00 0.9892
147 4295 trypsin activity H004648_01 Tryptase gamma 1 NM_012467 278275 TPSG1 0.816 1.161 1.42 0.06632
148 4295 trypsin activity H006381_01 Protease, serine, 23 AF015287 325820 SPUVE 1.423 2.047 1.44 0.18652
149 4295 trypsin activity H007042_01 Complement C1r-like proteinase precursor, AF178985 98571 LOC51279 1.077 0.984 0.91 0.48438
150 4295 trypsin activity H015697_01 Transmembrane protease, serine 3 NM_024022 298241 TMPRSS3 0.984 0.702 0.71 0.11262
151 4295 trypsin activity H001308_01 Proteinase 3 (serine proteinase, neutrophil, Wegener granulomatosis autoantigen) X55668 928 PRTN3 0.819 1.211 1.48 0.216
152 4295 trypsin activity H001448_01 HtrA-like serine protease NM_013247 115721 OMI 1.18 1.41 1.19 0.18541
153 43087 regulation of GTPase activity H004224_01 Hypothetical protein FLJ10767 AK001629 25584 FLJ10767 1.675 1.3 0.78 0.04097
154 43087 regulation of GTPase activity H004509_01 KIAA0782 protein AB018325 21264 KIAA0782 1.008 0.783 0.78 0.1811
155 43087 regulation of GTPase activity H008446_01 KIAA0167 gene product D79989 184884 KIAA0167 0.828 0.72 0.87 0.28232
156 43087 regulation of GTPase activity H009484_01 G protein-coupled receptor kinase-interactor 1 NM_014030 318339 GIT1 0.932 1.279 1.37 0.16443
157 43087 regulation of GTPase activity H001587_01 GDP dissociation inhibitor 1 X79353 74576 GDI1 1.606 1.015 0.63 0.03322
158 43087 regulation of GTPase activity H001635_01 GDP dissociation inhibitor 2 Y13286 56845 GDI2 1.474 1.137 0.77 0.12277
159 6687 glycosphingolipid metabolism H003235_01 GM2 ganglioside activator protein X62078 69743 GM2A 1.515 1.201 0.79 0.31178
160 6687 glycosphingolipid metabolism H004193_01 Sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; GM3 synthase) AB018356 225939 SIAT9 1.124 0.714 0.64 0.07436
161 6687 glycosphingolipid metabolism H006323_01 CMP-NeuAC:(beta)-N-acetylgalactosaminide (alpha)2,6-sialyltransferase member VI AB035173 109672 VI 3.293 2.391 0.73 0.27588
162 6687 glycosphingolipid metabolism H000076_01 UDP-glucose ceramide glucosyltransferase D50840 152601 UGCG 1.149 1.557 1.36 0.27117
163 6687 glycosphingolipid metabolism H000887_01 Prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) J03077 78575 PSAP 5.938 4.713 0.79 0.08217
164 6687 glycosphingolipid metabolism H001450_01 Globotriaosylceramide/CD77 synthase; Gb3/CD77 synthase; alpha1,4-galactosyltransferase; 4-N-acetylgl NM_017436 105956 A14GALT 3.059 2.119 0.69 0.26431
165 30148 sphingolipid biosynthesis H004193_01 Sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; GM3 synthase) AB018356 225939 SIAT9 1.124 0.714 0.64 0.07436
166 30148 sphingolipid biosynthesis H006323_01 CMP-NeuAC:(beta)-N-acetylgalactosaminide (alpha)2,6-sialyltransferase member VI AB035173 109672 VI 3.293 2.391 0.73 0.27588
167 30148 sphingolipid biosynthesis H000076_01 UDP-glucose ceramide glucosyltransferase D50840 152601 UGCG 1.149 1.557 1.36 0.27117
168 30148 sphingolipid biosynthesis H015734_01 Sphingosine kinase type 2 isoform AL136701 301305 SPHK2 1.457 0.927 0.64 0.1341
169 30148 sphingolipid biosynthesis H001450_01 Globotriaosylceramide/CD77 synthase; Gb3/CD77 synthase; alpha1,4-galactosyltransferase; 4-N-acetylgl NM_017436 105956 A14GALT 3.059 2.119 0.69 0.26431
170 6664 glycolipid metabolism H003235_01 GM2 ganglioside activator protein X62078 69743 GM2A 1.515 1.201 0.79 0.31178
171 6664 glycolipid metabolism H004193_01 Sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; GM3 synthase) AB018356 225939 SIAT9 1.124 0.714 0.64 0.07436
172 6664 glycolipid metabolism H006323_01 CMP-NeuAC:(beta)-N-acetylgalactosaminide (alpha)2,6-sialyltransferase member VI AB035173 109672 VI 3.293 2.391 0.73 0.27588
173 6664 glycolipid metabolism H006408_01 Alpha2,3-sialyltransferase AK001922 34578 ST3GALVI 0.717 0.581 0.81 0.33202
174 6664 glycolipid metabolism H000076_01 UDP-glucose ceramide glucosyltransferase D50840 152601 UGCG 1.149 1.557 1.36 0.27117
175 6664 glycolipid metabolism H000887_01 Prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) J03077 78575 PSAP 5.938 4.713 0.79 0.08217
176 6664 glycolipid metabolism H001148_01 Galactosylceramidase (Krabbe disease) NM_000153 273 GALC 1.388 1.872 1.35 0.2603
177 6664 glycolipid metabolism H001450_01 Globotriaosylceramide/CD77 synthase; Gb3/CD77 synthase; alpha1,4-galactosyltransferase; 4-N-acetylgl NM_017436 105956 A14GALT 3.059 2.119 0.69 0.26431