PUBLICATIONS
- Lim D, Lutucuta S, Bachireddy P, Youker K, Evans A, Entman M, Roberts R, Marian AJ. Angiotensin II Blockade Reverses Myocardial Fibrosis in a Transgenic Mouse Model of Human Hypertrophic Cardiomyopathy. Circulation; 2001;103:789-791
- Lutucuta S, Ballantyne CM, Elghannam H, Ferlic L, Gotto Jr. AM, Marian AJ. Novel Polymorphisms in the Promoter region of ABCA1 Gene and Plasma Lipids and Severity, Progression, and Regression of Coronary Atherosclerosis and Response to Therapy. Circulation Research, 2001; 88:969-973
- Nagueh SF, Bachinski L, Meyer D, Hill R, Zoghbi WA, Tam JW, Quinones MA, Roberts R, Marian AJ. Tissue Doppler imaging consistently detects myocardial abnormalities in patients with hypertrophic cardiomyopathy and provides a novel means for an early diagnosis prior to and independent of hypertrophy. Circulation: 2001; 104: 128-130
- Patel R, Nagueh SF, Tsybouleva N, Abdellatif M, Lutucuta S,.Kopelen HA, Quninoes MA, Zoghbi WA, Entman ML, Roberts R, Marian AJ. Simvastatin Induces Regression of Cardiac Hypertrophy and Fibrosis and Improves Cardiac Function in a Transgenic Rabbit Model of Human Hypertrophic Cardiomyopathy. Circulation 2001; 104:r27-r34 (Rapid track electronic publication). And 2001; 104: 317-324
- Ma K, Cilingiroglu M, Orvos JD, Ballantyne CM, Marian AJ, Chan L. Endothelial lipase is a major genetic determinant for high-density lipoprotein concentration, structure and metabolism. Proceedings of National Academy of Sciences, USA. 2003; 100: 2748-2753
- Nagueh SF, McFalls J, Meyer D, Hill R, Zoghbi WA, Tam JW, Quiñones MA, Roberts R, Marian AJ. Tissue Doppler imaging predicts the development of hypertrophic cardiomyopathy in subjects with Subclinical Disease. Circulation; 2003; 108: 395-398
- Tsybouleva N, Zhang L, Patel R, Nemoto S, DeFreitas G, Lutucuta S, , Entman M, Carabello B, Roberts R, Marian AJ. Aldosterone, through novel signaling proteins, is a fundamental molecular bridge between the genetic defect and the cardiac phenotype of familial hypertrophic cardiomyopathy. Circulation; 2004: 109: 1284-91
- Lutucuta S, Tsybouleva N, Ishiyama M, De Freitas G, Wei L, Carabello B, Marian AJ. Induction and reversal of the primary cardiac phenotype of human hypertrophic cardiomyopathy mutation cardiac troponin T-Q92 in switch on-switch off bigenic mice. JACC. 2004; 44: 2221-2230
- Sidhu JS, Rajawat YS, Rami TG, Gollob MH, Wang Z, Yuan R, Marian AJ, DeMayo FJ, Weilbacher D, Taffet GE, Carling D, Khoury DS, Roberts R. A transgenic mouse model of ventricular pre-excitation and atrioventricular re-entrant tachycardia induced by an AMPK loss of function mutation responsible for Wolff-Parkinson-White syndrome. Circulation. 2005: 111: 21-29
- Chen S, Ballantyne CM, Tan Y, Gotto, Jr. AM, Willerson JT, Marian AJ. A common PCSK9 haplotype, encompassing the G670Q cSNP, is associated with plasma low-density lipoprotein-cholesterol levels and severity of coronary atherosclerosis. JACC 2005; 45: 1611-1619
- Senthil V, Chen SN, Tsybouleva N, Halder T, Nagueh S, Willerson JT, Roberts R. Marian AJ. Prevention of cardiac hypertrophy by atorvastatin in a transgenic rabbit model of human hypertrophic cardiomyopathy. Circ. Res. 2005; 97: 285-292
- Schillinger KJ, Tsai SY, Taffet GE, Reddy AK, Marian AJ, Entman ML, Oka K, Chan L, O’Malley BW. Regulatable Atrial Natriuretic Peptide Gene Therapy for Hypertension. Proceedings of National Academy of Sciences, USA. 2005; 102: 13789 - 13794
- Marian AJ, Senthil V, Chen SN, Lombardi R. Anti-fibrotic effects of anti-oxidant N-Acetylcysteine in a mouse model of human hypertrophic cardiomyopathy mutation. J. Am. Coll. Cardiol. 2006; 47: 827-834
- Garcia-Gras, E, Lombardi R, Schneider MD, Willerson JT, Marian AJ. Suppression of canonical Wnt/b-Catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy. Journal of Clinical Investigation; 2006; 117; 2012-2021
- Osio A, Tan Y, Chen SN, Lombardi R, Roberts R, Willerson JT, Marian AJ. Myozenin 2 is a novel gene for human hypertrophic cardiomyopathy. Circ Res. 2007; 100: 766-768